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1. Full Text Mouse hepatitis virus infection remodels connexin43-mediated gap junction intercellular communication in vitro and in vivo
by Basu, Rahul and Banerjee, Kaveri and Bose, Abhishek and Sarma, Jayasri Das
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 5, pp. 2586 - 2599
Gap junctions (GJs) form intercellular channels which directly connect the cytoplasm between neighboring cells to facilitate the transfer of ions and small... 
OCULODENTODIGITAL DYSPLASIA | GLIOMA-CELLS | CONNEXIN-43 | VIROLOGY | MULTIPLE-SCLEROSIS | CORONAVIRUS INFECTION | CALCIUM WAVES | CULTURED ASTROCYTES | NONDEMYELINATING STRAINS | EXPRESSION | OSTEOBLASTIC CELLS | Connexin 43 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Brain - virology | Cell Communication | Murine hepatitis virus - growth & development | Host-Pathogen Interactions | Astrocytes - physiology | Animals | Gap Junctions - physiology | Coronavirus Infections - virology | Coronavirus Infections - pathology | Brain - pathology | Astrocytes - virology
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2. Full Text The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis
by Fehr, Anthony R and Athmer, Jeremiah and Channappanavar, Rudragouda and Phillips, Judith M and Meyerholz, David K and Perlman, Stanley
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 3, pp. 1523 - 1536
All coronaviruses encode a macrodomain containing ADP-ribose-1 ''-phosphatase (ADRP) activity within the N terminus of nonstructural protein 3 (nsp3). Previous... 
MURINE CORONAVIRUS | VIROLOGY | MOUSE HEPATITIS-VIRUS | NEUROTROPIC CORONAVIRUS | MACRO DOMAIN | CENTRAL-NERVOUS-SYSTEM | ADP-RIBOSE | REVERSE GENETICS | RESPIRATORY-SYNDROME CORONAVIRUS | T-CELLS | INFECTIOUS CDNA | Body Weight | Virulence Factors - genetics | Encephalitis, Viral - virology | Virulence | Male | Murine hepatitis virus - growth & development | Mutation, Missense | Viral Load | Leukocytes - immunology | Disease Models, Animal | Mice, Inbred C57BL | Cytokines - secretion | Mutant Proteins - genetics | Viral Nonstructural Proteins - genetics | Mutant Proteins - metabolism | Murine hepatitis virus - pathogenicity | Point Mutation | Animals | Survival Analysis | Brain - pathology | Viral Nonstructural Proteins - metabolism | Virulence Factors - metabolism | Encephalitis, Viral - pathology | Brain - immunology | Murine hepatitis virus - genetics
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3. Full Text Achieving a Golden Mean: Mechanisms by Which Coronaviruses Ensure Synthesis of the Correct Stoichiometric Ratios of Viral Proteins
by Ewan P. Plant and Rasa Rakauskaitė and Deborah R. Taylor and Jonathan D. Dinman
Journal of Virology, ISSN 0022-538X, 05/2010, Volume 84, Issue 9, pp. 4330 - 4340
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
RIBOSOMAL FRAMESHIFTING EFFICIENCY | DOUBLE-STRANDED-RNA | VIRUS | VIROLOGY | TRANSCRIPTION | TY1 RETROTRANSPOSITION | PSEUDOKNOT | COMPONENT | TRANSLATION | MUTATIONAL ANALYSIS | INFECTIOUS CDNA | Protein Biosynthesis | Open Reading Frames | Models, Molecular | Murine hepatitis virus - growth & development | Murine hepatitis virus - pathogenicity | Murine hepatitis virus - physiology | SARS Virus - pathogenicity | SARS Virus - growth & development | Animals | Frameshifting, Ribosomal | RNA, Viral - genetics | SARS Virus - genetics | Gene Expression Regulation, Viral | SARS Virus - physiology | Mutation | Nucleic Acid Conformation | Viral Proteins - biosynthesis | Murine hepatitis virus - genetics | Virus-Cell Interactions
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4. Full Text The nucleocapsid protein of coronaviruses acts as a viral suppressor of RNA silencing in mammalian cells
by Cui, Lei and Wang, Haiying and Ji, Yanxi and Yang, Jie and Xu, Shan and Huang, Xingyu and Wang, Zidao and Qin, Lei and Tien, Po and Zhou, Xi and Guo, Deyin and Chen, Yu
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 17, pp. 9029 - 9043
RNA interference (RNAi) is a process of eukaryotic posttranscriptional gene silencing that functions in antiviral immunity in plants, nematodes, and insects.... 
I INTERFERON ANTAGONIST | DOUBLE-STRANDED-RNA | VIROLOGY | MOUSE HEPATITIS-VIRUS | SR-RICH MOTIF | ACCESSORY PROTEIN | SARS CORONAVIRUS | BINDING DOMAIN | DIMERIZATION DOMAIN | ACUTE RESPIRATORY SYNDROME | ANTIVIRAL IMMUNITY | Amino Acid Sequence | Cell Line | RNA, Small Interfering - genetics | Argonaute Proteins - genetics | Ribonuclease III - genetics | Severe Acute Respiratory Syndrome - virology | Nucleocapsid Proteins - biosynthesis | Humans | L Cells (Cell Line) | Murine hepatitis virus - growth & development | Coronavirus - immunology | Murine hepatitis virus - immunology | DEAD-box RNA Helicases - genetics | Sequence Alignment | Animals | Nucleocapsid Proteins - genetics | RNA Interference | Base Sequence | HEK293 Cells | Coronavirus - genetics | Severe Acute Respiratory Syndrome - genetics | Mice | Murine hepatitis virus - genetics
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5. Full Text Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus
by Mangale, Vrushali and Marro, Brett S and Plaisted, Warren C and Walsh, Craig M and Lane, Thomas E
Virology, ISSN 0042-6822, 11/2017, Volume 511, pp. 49 - 55
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the... 
Neural progenitor cells | Viral receptor | Cytopathology | Mouse hepatitis virus | VIRAL MODEL | MOUSE HEPATITIS-VIRUS | COMMITTED PROGENITOR CELLS | RECEPTOR | AUTOIMMUNE ENCEPHALOMYELITIS | TRANSPLANTATION | VIROLOGY | MULTIPLE-SCLEROSIS | LOCOMOTOR RECOVERY | MEDIATED SUPPRESSION | MICE | Gene Expression | Induced Pluripotent Stem Cells - physiology | Neural Stem Cells - virology | Histocompatibility Antigens Class II - biosynthesis | Mice, Transgenic | Murine hepatitis virus - growth & development | Interferon-gamma - metabolism | Murine hepatitis virus - immunology | Neural Stem Cells - immunology | Animals | Carcinoembryonic Antigen - biosynthesis | Cell Differentiation | Histocompatibility Antigens Class I - biosynthesis | Mice | Virus diseases | Disease susceptibility | Genetic engineering | Health aspects | CEA (Oncology) | Stem cells | Hepatitis | Medical colleges | Microbiology | mouse hepatitis virus | viral receptor | cytopathology
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6. Full Text Cyclosporin A inhibits the replication of diverse coronaviruses
by de Wilde, Adriaan H and Zevenhoven-Dobbe, Jessika C and van der Meer, Yvonne and Thiel, Volker and Narayanan, Krishna and Makino, Shinji and Snijder, Eric J and van Hemert, Martijn J
Journal of General Virology, ISSN 0022-1317, 11/2011, Volume 92, Issue 11, pp. 2542 - 2548
Low micromolar, non-cytotoxic concentrations of cyclosporin A (CsA) strongly affected the replication of severe acute respiratory syndrome coronavirus... 
POTENT INHIBITOR | C VIRUS-REPLICATION | IN-VITRO | PROTEIN | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DEBIO-025 | CHLOROQUINE | HEPATITIS-C | EXPRESSION | RESPIRATORY SYNDROME CORONAVIRUS | CYCLOPHILIN | Cell Line | Coronavirus 229E, Human - drug effects | Green Fluorescent Proteins - metabolism | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cyclosporine - pharmacology | Humans | SARS Virus - drug effects | Murine hepatitis virus - drug effects | Green Fluorescent Proteins - genetics | Murine hepatitis virus - growth & development | Viral Load | SARS Virus - growth & development | Animals | Genes, Reporter | Coronavirus 229E, Human - growth & development | Animal | Short Communication
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7. Full Text Remyelination is correlated with regulatory T cell induction following human embryoid body-derived neural precursor cell transplantation in a viral model of multiple sclerosis
by Plaisted, Warren C and Zavala, Angel and Hingco, Edna and Tran, Ha and Coleman, Ronald and Lane, Thomas E and Loring, Jeanne F and Walsh, Craig M
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, p. e0157620
We have recently described sustained clinical recovery associated with dampened neuroinflammation and remyelination following transplantation of neural... 
RECOVERY | DEMYELINATION | CONVERSION | MULTIDISCIPLINARY SCIENCES | DISEASE | NERVOUS-SYSTEM INFLAMMATION | DIFFERENTIATION | CORONAVIRUS | RAT MODEL | AUTOIMMUNE ENCEPHALOMYELITIS | NEUROPROTECTION | Forkhead Transcription Factors - immunology | Cell- and Tissue-Based Therapy - methods | Human Embryonic Stem Cells - cytology | Humans | Male | Murine hepatitis virus - growth & development | Neural Stem Cells - cytology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Neural Stem Cells - immunology | Embryoid Bodies - cytology | Human Embryonic Stem Cells - immunology | Neural Stem Cells - transplantation | Cell Differentiation | Hepatitis, Viral, Animal - virology | Hepatitis, Viral, Animal - therapy | CD4 Antigens - genetics | Disease Models, Animal | Biomarkers - metabolism | Hepatitis, Viral, Animal - immunology | Hepatitis, Viral, Animal - pathology | CD4 Antigens - immunology | Gene Expression | Myelin Sheath - immunology | Lymphocyte Activation | Mice, Inbred C57BL | Forkhead Transcription Factors - genetics | Murine hepatitis virus - pathogenicity | Organ Specificity | Coronavirus Infections - immunology | Multiple Sclerosis - therapy | Animals | Coronavirus Infections - virology | Coronavirus Infections - therapy | Coronavirus Infections - pathology | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Mice | Embryoid Bodies - immunology | Cell culture | Multiple sclerosis | Spinal cord | Transplants & implants | Embryo cells | Central nervous system | Stem cell transplantation | Viruses | Nervous system | Transplantation | Lymphocytes T | Biochemistry | Recovery | Hepatitis | Immunology | Demyelination | Lymphocytes | Precursors | Rodents | Neural cell transplants | Cell cycle | Foxp3 protein | Physiology | Immunoregulation | Inflammation | Gene expression | CD4 antigen | Medicine | Myelination | Brain research | Stem cells | Molecular biology | Differentiation | Pluripotency
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8. Full Text Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions
by Al-Mulla, Hawaa M. N and Turrell, Lauren and Smith, Nicola M and Payne, Luke and Baliji, Surendranath and Züst, Roland and Thiel, Volker and Baker, Susan C and Siddell, Stuart G and Neuman, Benjamin W
mBio, ISSN 2161-2129, 04/2014, Volume 5, Issue 2, p. e01107
Positive-stranded viruses synthesize their RNA in membrane-bound organelles, but it is not clear how this benefits the virus or the host. For coronaviruses,... 
LOCALIZATION | MUTANTS | RNA-SYNTHESIS | GENETIC-ANALYSIS | PROTEIN | MOUSE HEPATITIS-VIRUS | COMPLEXES | MICROBIOLOGY | POLYPROTEIN | VIRAL REPLICATION | SARS-CORONAVIRUS | Temperature | Cells, Cultured | Viral Nonstructural Proteins - genetics | Murine hepatitis virus - growth & development | Microscopy, Electron | Murine hepatitis virus - physiology | Cytoplasmic Vesicles - virology | Host-Pathogen Interactions | Animals | Virus Replication | Viral Nonstructural Proteins - metabolism | Mice | Mutation
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9. Full Text Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential
by Michael Zasloff and A. Paige Adams and Bernard Beckerman and Ann Campbell and Ziying Han and Erik Luijten and Isaura Meza and Justin Julander and Abhijit Mishra and Wei Qu and John M. Taylor and Scott C. Weaver and Gerard C. L. Wong
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 38, pp. 15978 - 15983
Antiviral compounds that increase the resistance of host tissues represent an attractive class of therapeutic. Here, we show that squalamine, a compound... 
Hepatocytes | Liver | Humans | Antivirals | Viruses | Lipids | Infections | Cell membranes | Endothelial cells | P branes | Innate immunity | Hepatitis B virus | Dengue virus | Eastern equine encephalitis virus | Yellow fever virus | FEVER VIRUS-INFECTION | MURINE CYTOMEGALOVIRUS-INFECTION | hepatitis B virus | MULTIDISCIPLINARY SCIENCES | dengue virus | HAMSTER MESOCRICETUS-AURATUS | MATRIX DOMAIN | YELLOW-FEVER | GAG MEMBRANE-BINDING | VACCINE CANDIDATES | yellow fever virus | innate immunity | eastern equine encephalitis virus | EASTERN EQUINE ENCEPHALITIS | ANGIOGENESIS INHIBITOR | Hepatitis B virus - growth & development | Male | Virus Diseases - virology | Cell Membrane - chemistry | Cholestanols - chemistry | Virus Diseases - drug therapy | Antiviral Agents - chemistry | X-Ray Diffraction | Anti-Bacterial Agents - chemistry | Mesocricetus | Female | Hepatitis Delta Virus - drug effects | Molecular Structure | rac1 GTP-Binding Protein - chemistry | Cell Membrane - drug effects | Hepatocytes - drug effects | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cricetinae | Hepatitis Delta Virus - growth & development | Cells, Cultured | Scattering, Small Angle | Muromegalovirus - growth & development | Muromegalovirus - drug effects | Cholestanols - pharmacology | Hepatitis B virus - drug effects | Animals | Hepatocytes - virology | Anti-Bacterial Agents - pharmacology | Mice | Mice, Inbred BALB C | Antiviral agents | Research | Health aspects | Biological Sciences
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10. Full Text Enzymatic and viability RT‐qPCR assays for evaluation of enterovirus, hepatitis A virus and norovirus inactivation: Implications for public health risk assessment
by Monteiro, S and Santos, R
Journal of Applied Microbiology, ISSN 1364-5072, 04/2018, Volume 124, Issue 4, pp. 965 - 976
Aim To assess the potential of a viability dye and an enzymatic reverse transcription quantitative PCR (RT‐qPCR) pretreatment to discriminate between... 
viruses | enzymatic PCR | infectivity | heat inactivation | viability PCR | public health | LISTERIA-MONOCYTOGENES | ETHIDIUM MONOAZIDE TREATMENT | FRESH-CUT VEGETABLES | QUANTITATIVE PCR | MICROBIOLOGY | REAL-TIME PCR | ENTERIC VIRUSES | REVERSE-TRANSCRIPTION-PCR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MICROBIAL INDICATORS | MURINE NOROVIRUS-1 | PROPIDIUM MONOAZIDE | Norovirus - chemistry | Norovirus - physiology | Caliciviridae Infections - virology | Ribonucleases - chemistry | Hepatitis A virus - genetics | Humans | Real-Time Polymerase Chain Reaction - methods | Enterovirus - isolation & purification | Hot Temperature | Reverse Transcriptase Polymerase Chain Reaction | Hepatitis A virus - physiology | Enterovirus - chemistry | Enterovirus - genetics | Enterovirus Infections - virology | Norovirus - growth & development | Enterovirus - growth & development | Hepatitis A - virology | Hepatitis A virus - growth & development | Hepatitis A virus - chemistry | Virus Inactivation | Norovirus - genetics | Hepatitis A virus | Surface active agents | Risk assessment | Diagnosis | Ribonuclease | Health aspects | Hepatitis A | Public health | Cell culture | Dyes | Deactivation | Triton | Health risks | Reverse transcription | Viruses | Surfactants | Inactivation | Assaying | Hepatitis | Enteroviruses | Ribonuclease IV | Infectious diseases | Infectivity | Plaque assay | Pretreatment | Pollutants | Health risk assessment | Viability
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11. Full Text Mouse Hepatitis Virus Stem-Loop 4 Functions as a Spacer Element Required To Drive Subgenomic RNA Synthesis
by Dong Yang and Pinghua Liu and David P. Giedroc and Julian Leibowitz
Journal of Virology, ISSN 0022-538X, 09/2011, Volume 85, Issue 17, pp. 9199 - 9209
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
5'-UNTRANSLATED REGION | REPLICATION | VIROLOGY | MESSENGER-RNA | VIRAL TRANSCRIPTION | TRANSCRIPTION-REGULATING SEQUENCES | MURINE CORONAVIRUSES | CIS-ACTING ELEMENT | CORONAVIRUS TRANSCRIPTION | LEADER RNA | BINDING PROTEIN | Sequence Deletion | Open Reading Frames | Models, Molecular | Viral Plaque Assay | Murine hepatitis virus - growth & development | Microbial Viability | Murine hepatitis virus - physiology | Animals | RNA, Viral - genetics | Base Pairing | Virus Replication | 5' Untranslated Regions | Transcription, Genetic | RNA, Viral - metabolism | Mutation | Nucleic Acid Conformation | Murine hepatitis virus - genetics | Suppression, Genetic | Genome and Regulation of Viral Gene Expression
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12. Full Text Organ-Specific Attenuation of Murine Hepatitis Virus Strain A59 by Replacement of Catalytic Residues in the Putative Viral Cyclic Phosphodiesterase ns2
by Jessica K. Roth-Cross and Helen Stokes and Guohui Chang and Ming Ming Chua and Volker Thiel and Susan R. Weiss and Alexander E. Gorbalenya and Stuart G. Siddell
Journal of Virology, ISSN 0022-538X, 04/2009, Volume 83, Issue 8, pp. 3743 - 3753
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ACUTE-RESPIRATORY-SYNDROME | IN-VITRO | VIROLOGY | PROTEIN SECONDARY STRUCTURE | SPIKE PROTEIN | NUCLEOCAPSID PROTEIN | NONSTRUCTURAL PROTEIN-3 | VACCINIA VIRUS | SYNDROME CORONAVIRUS | SARS-CORONAVIRUS | STRUCTURE PREDICTION | Fibroblasts - virology | Liver - virology | Mutagenesis, Site-Directed | Phosphoric Diester Hydrolases - metabolism | Cells, Cultured | Brain - virology | Murine hepatitis virus - growth & development | Phosphoric Diester Hydrolases - genetics | Mutation, Missense | Murine hepatitis virus - pathogenicity | Murine hepatitis virus - enzymology | Animals | Coronavirus Infections - virology | Amino Acid Substitution - genetics | Mice | Index Medicus | Genome and Regulation of Viral Gene Expression
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13. Full Text The Small Envelope Protein E Is Not Essential for Murine Coronavirus Replication
by Lili Kuo and Paul S. Masters
Journal of Virology, ISSN 0022-538X, 04/2003, Volume 77, Issue 8, pp. 4597 - 4608
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
INTERNAL RIBOSOME ENTRY | VIROLOGY | MOUSE HEPATITIS-VIRUS | TRANSMISSIBLE GASTROENTERITIS CORONAVIRUS | PARTICLES | TARGETED RNA RECOMBINATION | MEMBRANE-PROTEIN | VIRION ENVELOPE | INFECTED-CELLS | REVERSE GENETICS | GOLGI-COMPLEX | Amino Acid Sequence | Viral Envelope Proteins - genetics | Viral Plaque Assay | Murine hepatitis virus - growth & development | Murine hepatitis virus - physiology | Animals | RNA, Viral - genetics | Virus Replication | Recombination, Genetic | Base Sequence | Gene Deletion | Viral Envelope Proteins - metabolism | Mice | Murine hepatitis virus - genetics | Structure and Assembly
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14. Full Text An Optimal cis-Replication Stem-Loop IV in the 5′ Untranslated Region of the Mouse Coronavirus Genome Extends 16 Nucleotides into Open Reading Frame 1
by Bo-Jhih Guan and Hung-Yi Wu and David A. Brian
Journal of Virology, ISSN 0022-538X, 06/2011, Volume 85, Issue 11, pp. 5593 - 5605
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
MURINE CORONAVIRUS | 5'-UNTRANSLATED REGION | 3' END | PROTEIN | VIROLOGY | HEPATITIS-VIRUS | DEFECTIVE INTERFERING RNA | ACTING ELEMENT | SECONDARY STRUCTURE | PERSISTENT INFECTION | RESPIRATORY-SYNDROME CORONAVIRUS | Cell Line | Open Reading Frames | Viral Plaque Assay | Murine hepatitis virus - growth & development | Microbial Viability | Murine hepatitis virus - physiology | Animals | RNA, Viral - genetics | Virus Replication | 5' Untranslated Regions | Recombination, Genetic | Coronavirus, Bovine - genetics | Murine hepatitis virus - genetics | Genome and Regulation of Viral Gene Expression
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