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Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6606 - 6606
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 12/2015, Volume 176, pp. 225 - 231
(Araceae) is a horticulture plant also used by some traditional medicine practitioners in the treatment of diarrhoea and other gastrointestinal disorders. This... 
Mechanisms of action | Araceae | α2-adrenoceptors | Muscarinic receptors | Caladium bicolor | Antidiarrhoeal activity | adrenoceptors | TRANSIT | CHEMISTRY, MEDICINAL | CHOLERA | DIARRHEAL DISEASES | AGONISTS | PLANT SCIENCES | INTESTINAL INFLAMMATION | alpha-adrenoceptors | PROSTAGLANDINS | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | MICE | RICINOLEIC ACID | WATER | Plant Extracts - toxicity | Muscarinic Agonists - pharmacology | Plant Extracts - pharmacology | Male | Toxicity Tests, Acute | Muscarinic Antagonists - therapeutic use | Diarrhea - chemically induced | Adrenergic alpha-2 Receptor Agonists - pharmacology | Yohimbine - pharmacology | Antidiarrheals - pharmacology | Adrenergic alpha-2 Receptor Agonists - therapeutic use | Muscarinic Antagonists - pharmacology | Water - chemistry | Female | Phytotherapy | Plant Leaves - chemistry | Muscarinic Antagonists - toxicity | Rats | Gastrointestinal Transit - drug effects | Adrenergic alpha-2 Receptor Antagonists - pharmacology | Adrenergic alpha-2 Receptor Agonists - toxicity | Animals | Antidiarrheals - therapeutic use | Castor Oil | Gastric Emptying - drug effects | Pilocarpine - pharmacology | Diarrhea - metabolism | Diarrhea - drug therapy | Intestinal Secretions - metabolism | Mice | Antidiarrheals - toxicity | Plant Extracts - therapeutic use | Gastrointestinal diseases | Medicine, Botanic | Medicine, Herbal | Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 10/2012, Volume 76, Issue 2, pp. 396 - 409
Adhesive contact between pre- and postsynaptic neurons initiates synapse formation during brain development and provides a natural means of transsynaptic... 
RELEASE PROBABILITY | AMPA RECEPTORS | TISSUE-PLASMINOGEN ACTIVATOR | NMDA RECEPTORS | VISUAL-CORTEX | MATRIX-METALLOPROTEINASE | CELL-ADHESION MOLECULES | LONG-TERM POTENTIATION | NEUROSCIENCES | INHIBITORY SYNAPSE FORMATION | PLASTICITY | Electric Stimulation | Synaptic Transmission - genetics | Dark Adaptation - genetics | Status Epilepticus - chemically induced | Dendrites - ultrastructure | Green Fluorescent Proteins - genetics | Pilocarpine - toxicity | Matrix Metalloproteinase 9 - metabolism | Muscarinic Agonists - toxicity | Excitatory Amino Acid Agents - pharmacology | Synaptic Transmission - drug effects | Excitatory Postsynaptic Potentials - genetics | Organ Culture Techniques | Disease Models, Animal | Animals, Newborn | Glutamic Acid - pharmacology | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Signal Transduction - genetics | Mutation - genetics | Cell Adhesion Molecules, Neuronal - genetics | Microscopy, Confocal | Patch-Clamp Techniques | Signal Transduction - drug effects | Luminescent Proteins - genetics | Mice | Synaptic Transmission - physiology | Cercopithecus aethiops | Neurons - cytology | Threonine - metabolism | Cerebral Cortex - cytology | Excitatory Postsynaptic Potentials - drug effects | Transfection | Potassium Chloride - pharmacology | Threonine - genetics | Neurons - physiology | Female | Cell Adhesion Molecules, Neuronal - metabolism | Neurons - drug effects | Plant Lectins - genetics | Dendrites - metabolism | Biotinylation | Vesicular Glutamate Transport Protein 1 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Electroporation | Photons | Hippocampus - cytology | Pregnancy | Animals | Neural Cell Adhesion Molecules - metabolism | Quaternary Ammonium Compounds - metabolism | Signal Transduction - physiology | Plant Lectins - metabolism | Pyridinium Compounds - metabolism | Luminescent Proteins - metabolism | Methyl aspartate | Neurons | Neurosciences | Proteins | Studies | Brain | Autism | Net losses | Kinases | Index Medicus | Adhesives
Journal Article
Neuron, ISSN 0896-6273, 10/2012, Volume 76, Issue 2, pp. 410 - 422
Neuroligin (NLG), a postsynaptic adhesion molecule, is involved in the formation of synapses by binding to a cognate presynaptic ligand, neurexin. Here we... 
AMYLOID-BETA PEPTIDES | ALPHA-SECRETASE | SLICE CULTURES | SYNAPTIC FUNCTION | INHIBITORY SYNAPSES | PILOCARPINE MODEL | STATUS EPILEPTICUS | CELL-ADHESION | GAMMA-SECRETASE | NEUROSCIENCES | N-CADHERIN | Synaptosomes - drug effects | Rats, Wistar | Embryo, Mammalian | Humans | Status Epilepticus - chemically induced | Male | Dendritic Spines - metabolism | Green Fluorescent Proteins - genetics | Pilocarpine - toxicity | Synaptosomes - metabolism | Membrane Proteins - deficiency | Muscarinic Agonists - toxicity | Neurons - ultrastructure | Transfection | Proteolysis | Cell Adhesion Molecules, Neuronal - metabolism | RNA Interference - physiology | Organ Culture Techniques | Disease Models, Animal | Animals, Newborn | Green Fluorescent Proteins - metabolism | Biotinylation | Gene Expression Regulation - genetics | Cerebellum - metabolism | Dipeptides - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Status Epilepticus - pathology | ADAM Proteins - deficiency | ADAM10 Protein | Rats | Hippocampus - cytology | Nerve Tissue Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Neural Cell Adhesion Molecules - metabolism | Amyloid Precursor Protein Secretases - deficiency | Mice | Mice, Inbred BALB C | Status Epilepticus - metabolism | Methyl aspartate | Brain | Neurosciences | Evolutionary biology | Proteases | Neurons | Epilepsy | Medical law | Universities and colleges | Seizures (Medicine) | Proteins | Autism | Cell culture | Polypeptides | Brain research | Plasmids | Rodents | Science | Index Medicus | Indexing in process
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2011, Volume 31, Issue 42, pp. 14850 - 14860
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 12/2012, Volume 697, Issue 1-3, pp. 73 - 80
Benzylquinolone carboxylic acid (BQCA) is a recently described cholinergic muscarinic M receptor positive allosteric modulator having potential as cognitive... 
M1 positive allosteric modulator | BQCA | Muscarinic receptor | Rat | Memory | M | positive allosteric modulator | Memory - drug effects | Carboxylic Acids - toxicity | Cricetulus | Calcium - metabolism | Muscarinic Agonists - pharmacology | Nootropic Agents - metabolism | Motor Activity - drug effects | Male | Quinolones - pharmacology | Brain - metabolism | Cholinergic Fibers - metabolism | Dose-Response Relationship, Drug | Scopolamine Hydrobromide - pharmacology | Muscarinic Agonists - toxicity | Transfection | Receptor, Muscarinic M1 - drug effects | Muscarinic Antagonists - pharmacology | Muscarinic Agonists - metabolism | Behavior, Animal - drug effects | Carboxylic Acids - administration & dosage | Cholinergic Fibers - drug effects | CHO Cells | Carboxylic Acids - pharmacology | Cricetinae | Muscarinic Agonists - administration & dosage | Quinolones - toxicity | Salivation - drug effects | Quinuclidines - pharmacology | Injections, Intraperitoneal | Quinolones - metabolism | Rats | Thiophenes - pharmacology | Maze Learning - drug effects | Rats, Sprague-Dawley | Brain - drug effects | Nootropic Agents - toxicity | Receptor, Muscarinic M1 - genetics | Quinolones - administration & dosage | Animals | Microdialysis | Nootropic Agents - administration & dosage | Carboxylic Acids - metabolism | Nootropic Agents - pharmacology | Receptor, Muscarinic M1 - metabolism | Index Medicus | Potentiation | Brain | Animal models | Acetylcholine receptors (muscarinic) | Neurodegenerative diseases | Cognitive ability | Spontaneous alternation | Data processing | Locomotion | Allosteric properties | Side effects | carboxylic acids | Dementia disorders | Alzheimer's disease | Communication | Neuroscience | Cognitive science
Journal Article