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Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 4/2009, Volume 379, Issue 4, pp. 389 - 395
Journal Article
Journal Article
Journal Article
2012, First, Handbook of experimental pharmacology, ISBN 3642232736, Volume 208, xiii, 499
Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies... 
Muscarinic receptors | Biology, life sciences | Receptors | Acetylcholine | Molecular pharmacology | Biomedicine | Human Physiology | Pharmacology/Toxicology | Endocrinology | Neurobiology | Cell Biology
Book
Journal of Psychopharmacology, ISSN 0269-8811, 01/2009, Volume 23, Issue 1, pp. 65 - 73
Asenapine is a novel psychopharmacologic agent under development for the treatment of schizophrenia and bipolar disorder. We determined and compared the human... 
Schizophrenia | Affinity | Bipolar disorder | Asenapine | Human receptor | NEGATIVE SYMPTOMS | PSYCHIATRY | FOCUS | SEROTONIN RECEPTORS | DISORDERS | RISPERIDONE | schizophrenia | COGNITION | NEUROSCIENCES | CLINICAL NEUROLOGY | bipolar disorder | DOPAMINE D-3 RECEPTOR | PSYCHOSIS | ATYPICAL ANTIPSYCHOTIC-DRUG | PHARMACOLOGY & PHARMACY | asenapine | human receptor | affinity | Humans | Receptors, Serotonin - drug effects | Substrate Specificity | Receptors, Serotonin - genetics | Heterocyclic Compounds, 4 or More Rings - pharmacology | Psychotropic Drugs - therapeutic use | Receptors, Dopamine - drug effects | Clozapine - pharmacology | Histamine Release - genetics | Receptors, Muscarinic - drug effects | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Receptors, Adrenergic - drug effects | Psychotropic Drugs - pharmacology | Cloning, Molecular | Receptors, Adrenergic - genetics | Receptors, Dopamine D2 - drug effects | Inhibitory Concentration 50 | Molecular Structure | Radioligand Assay | Histamine Release - drug effects | Receptors, Muscarinic - genetics | Benzodiazepines - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Clinical Trials as Topic | Psychotropic Drugs - chemistry | Bipolar Disorder - drug therapy | Receptors, Dopamine D2 - physiology | Schizophrenia - drug therapy | Receptors, Dopamine - genetics | Histamine receptors | Drugs | Neuroleptics | Olanzapine | Acetylcholine receptors (muscarinic) | Mental disorders | Dopamine D4 receptors | Serotonin S1 receptors | Serotonin S7 receptors | Psychotropic drugs | Receptors | Histamine H2 receptors | Risperidone | Dopamine D2 receptors | Dopamine receptors | Binding | Dopamine | Serotonin | Dopamine D3 receptors | Serotonin S6 receptors | Serotonin S2 receptors | Histamine | Dopamine D1 receptors | Serotonin receptors | Receptors (physiology) | Index Medicus
Journal Article
Life Sciences, ISSN 0024-3205, 05/2007, Volume 80, Issue 24-25, pp. 2303 - 2307
Journal Article
Neuroscience, ISSN 0306-4522, 2010, Volume 169, Issue 4, pp. 1610 - 1620
Abstract We have shown that cortical acetylcholine modulates the balance between excitation and inhibition evoked in layer 5 pyramidal neurons of rat visual... 
Neurology | pyramidal neuron | acetylcholine | M1- M2- M3- M4- M5-muscarinic receptors | cortical network | Acetylcholine | Cortical network | Pyramidal neuron | GABAERGIC TRANSMISSION | SYNAPTIC-TRANSMISSION | NEUROSCIENCES | ACETYLCHOLINE-RECEPTOR | CEREBRAL-CORTEX | IN-VITRO | CORTICAL-NEURONS | M1-M2-M3-M4-M5-muscarinic receptors | AUDITORY-CORTEX | CHOLINERGIC MODULATION | POSTNATAL-DEVELOPMENT | HIPPOCAMPAL PYRAMIDAL CELLS | Pyramidal Cells - metabolism | Rats, Wistar | Receptor, Muscarinic M4 - physiology | Receptor, Muscarinic M1 - antagonists & inhibitors | Receptor, Muscarinic M3 - physiology | Receptors, Muscarinic - metabolism | Receptor, Muscarinic M1 - physiology | Excitatory Postsynaptic Potentials - drug effects | Receptor, Muscarinic M2 - physiology | Visual Cortex - physiology | Excitatory Postsynaptic Potentials - physiology | Neural Inhibition - physiology | Muscarinic Antagonists - pharmacology | Pyramidal Cells - physiology | Receptor, Muscarinic M2 - antagonists & inhibitors | Glutamic Acid - secretion | Pyramidal Cells - drug effects | Organ Culture Techniques | Inhibitory Postsynaptic Potentials - physiology | Rats | Receptor, Muscarinic M3 - antagonists & inhibitors | Animals | Glutamic Acid - metabolism | Visual Cortex - drug effects | Neural Inhibition - drug effects | Receptor, Muscarinic M4 - antagonists & inhibitors | Inhibitory Postsynaptic Potentials - drug effects | Receptors, Muscarinic - physiology | Methyl aspartate | Cell research | Neurosciences | Neurons | GABA | Glutamate | Benzodiazepines | Acetylcholine receptors (muscarinic) | Neural Inhibition | Neurons and Cognition | Visual Cortex | Muscarinic Antagonists | Receptor, Muscarinic M1 | Receptor, Muscarinic M2 | Receptor, Muscarinic M3 | Receptor, Muscarinic M4 | Glutamic Acid | Life Sciences | Receptors, Muscarinic | Excitatory Postsynaptic Potentials | Pyramidal Cells | Inhibitory Postsynaptic Potentials
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 01/2003, Volume 50, Issue 1, pp. 5 - 25
The aim of the current study is to investigate whether homology models of G‐Protein‐Coupled Receptors (GPCRs) that are based on bovine rhodopsin are reliable... 
docking | scoring | homology modeling | GPCRs | structure‐based ligand design | Docking | Scoring | Structure-based ligand design | Homology modeling | BETA ADRENERGIC-RECEPTOR | AGONIST ACTIVATION | LIGAND-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | structure-based ligand design | MUSCARINIC RECEPTOR | DELTA-OPIOID RECEPTOR | INDUCED CONFORMATIONAL-CHANGES | TRANSMEMBRANE REGIONS | BIOPHYSICS | SCORING FUNCTIONS | 3-DIMENSIONAL MODELS | BETA-ADRENERGIC RECEPTOR | Humans | Molecular Sequence Data | Heterotrimeric GTP-Binding Proteins - metabolism | Adrenergic beta-2 Receptor Agonists | Receptors, Cell Surface - antagonists & inhibitors | Drug Delivery Systems | Receptors, Adrenergic, beta-2 - chemistry | Receptors, Vasopressin - chemistry | Cattle | Computer Simulation | Receptors, Dopamine D2 - chemistry | Receptors, Cell Surface - chemistry | Databases, Factual | Rhodopsin - chemistry | Amino Acid Sequence | Computational Biology - methods | Receptors, Opioid, delta - chemistry | Receptors, Dopamine D2 - agonists | Receptors, Cell Surface - agonists | Models, Molecular | Receptor, Muscarinic M1 | Receptors, Muscarinic - chemistry | Sequence Homology, Amino Acid | Sequence Alignment | Algorithms | Animals | Receptors, Dopamine D3 | Ligands | Antidiuretic Hormone Receptor Antagonists | Dopamine D2 Receptor Antagonists | Receptors, Opioid, delta - agonists
Journal Article