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Stem Cells, ISSN 1066-5099, 03/2010, Volume 28, Issue 3, pp. 564 - 572
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types. Chondrogenesis is induced in hMSCs cultured as a... 
Cell shape | Rac1 | Chondrogenesis | Smooth muscle cells | N-cadherin | Mesenchymal stem cells | MYOBLAST FUSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ADHESION | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | CYTOSKELETAL TENSION | DIFFERENTIATION | RHO-GTPASES | PROTEINS | HEMATOLOGY | MODULATION | MAMMARY EPITHELIAL-CELLS | Chondrocytes - cytology | Chondrogenesis - drug effects | Cadherins - metabolism | Humans | Extracellular Matrix - metabolism | Antigens, CD - genetics | Cell Lineage - drug effects | Transforming Growth Factor beta3 - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cadherins - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Cell Adhesion - genetics | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Mesenchymal Stromal Cells - metabolism | Up-Regulation - genetics | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion - drug effects | Cell Lineage - physiology | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Muscle Development - drug effects | rac1 GTP-Binding Protein - drug effects | Cell Differentiation - drug effects | Cell Shape - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus
Journal Article
Science, ISSN 0036-8075, 06/2016, Volume 352, Issue 6292, pp. 1436 - 1443
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2016, Volume 24, Issue 6, pp. 795 - 806
NAD availability decreases with age and in certain disease conditions. Nicotinamide mononucleotide (NMN), a key NAD intermediate, has been shown to enhance NAD... 
NAD | NAD+ precursor | insulin sensitivity | eye function | anti-aging | mitochondria | aging | nicotinamide mononucleotide | glucose metabolism | NMN | energy metabolism | precursor | LIFE-SPAN | STEM-CELLS | ACTIVATION | MITOCHONDRIAL | NAD BIOSYNTHESIS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | RIBOSIDE | SIRT1 | ADIPOSE-TISSUE | CELL BIOLOGY | Darkness | Aging - drug effects | Male | Muscle, Skeletal - metabolism | Nicotinamide Mononucleotide - administration & dosage | Aging - genetics | Time Factors | Lipids - blood | Muscle, Skeletal - drug effects | Cell Respiration - drug effects | Myeloid Cells - drug effects | Weight Gain - drug effects | NAD - metabolism | Physical Conditioning, Animal | Food | Lymphocytes - metabolism | Insulin - pharmacology | Administration, Oral | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Gene Expression Regulation - drug effects | Eating - drug effects | Bone Density - drug effects | Animals | Aging - physiology | Lymphocytes - drug effects | Myeloid Cells - metabolism | Nicotinamide Mononucleotide - pharmacology | Drinking - drug effects | Nicotinamide Mononucleotide - blood | Energy Metabolism - drug effects | Niacinamide | Medical colleges | Exercise | Pharmacy | Genes | Body weight | Physiological aspects | Muscles | Mice | Ophthalmology | Gene expression | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2016, Volume 22, Issue 1, pp. 78 - 83
Senescent cells (SCs) accumulate with age and after genotoxic stress, such as total-body irradiation (TBI)(1-6). Clearance of SCs in a progeroid mouse model... 
MEDICINE, RESEARCH & EXPERIMENTAL | SECRETORY PHENOTYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | P16(INK4A) | CELLULAR SENESCENCE | FAMILY | CELL BIOLOGY | POTENT | IN-VIVO | IONIZING-RADIATION | INHIBITOR | EXPRESSION | Whole-Body Irradiation | Apoptosis - drug effects | Humans | bcl-X Protein - genetics | Hematopoietic Stem Cells - pathology | Muscle, Skeletal - cytology | RNA, Messenger - metabolism | Gene Knockdown Techniques | Myoblasts - drug effects | Cyclin-Dependent Kinase Inhibitor p16 - drug effects | Cellular Senescence | Ganciclovir - pharmacology | Antineoplastic Agents - pharmacology | Colony-Forming Units Assay | RNA, Messenger - drug effects | Hematopoietic Stem Cells - drug effects | Cell Line | Cell Survival - drug effects | Antiviral Agents - pharmacology | Aniline Compounds - pharmacology | Rejuvenation | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Myoblasts - pathology | Sulfonamides - pharmacology | Blotting, Western | B-Lymphocytes - drug effects | Animals | Cell Cycle | Microscopy | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Mice | DNA Damage | Proto-Oncogene Proteins c-bcl-2 - genetics | Physiological aspects | Aging | Genetic aspects | Research | Hematopoietic stem cells | Cells | Bone marrow | Cytotoxicity | Senescence | Molecular biology | Stem cells | Apoptosis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E291 - E299
Protein transduction domains (PTDs) are powerful nongenetic tools that allow intracellular delivery of conjugated cargoes to modify cell behavior. Their use in... 
Human embryonic stem cells | Transduction | Cell-penetrating peptides | Differentiation | Heparin-binding domain | differentiation | transduction | MULTIDISCIPLINARY SCIENCES | MECHANISMS | HEPARIN | MAMMALIAN-CELLS | IPS CELLS | PLURIPOTENT STEM-CELLS | cell-penetrating peptides | heparin-binding domain | MACROPINOCYTOSIS | GROWTH-FACTOR | PROTEINS | human embryonic stem cells | NIH 3T3 Cells | Homeodomain Proteins - metabolism | Human Embryonic Stem Cells - cytology | Humans | Mouse Embryonic Stem Cells - cytology | Mouse Embryonic Stem Cells - drug effects | Mouse Embryonic Stem Cells - metabolism | Drug Delivery Systems | Nanoparticles | Human Embryonic Stem Cells - drug effects | Integrases - metabolism | Cell Membrane - metabolism | Cell Membrane - drug effects | Cell-Penetrating Peptides - chemistry | Induced Pluripotent Stem Cells - metabolism | Protein Structure, Tertiary | Detergents - pharmacology | Human Embryonic Stem Cells - metabolism | Nanog Homeobox Protein | Induced Pluripotent Stem Cells - drug effects | Glycosaminoglycans - metabolism | Endocytosis - drug effects | Solubility | MyoD Protein - metabolism | Nucleic Acids - metabolism | Trypsin - metabolism | Amino Acid Motifs | Animals | Muscle Development - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Genome | Cell-Penetrating Peptides - metabolism | Physiological aspects | Physiological research | Cellular signal transduction | Glycosaminoglycans | Research | Proteins | Peptides | Cytoplasm | Binding sites | Stem cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2006, Volume 25, Issue 24, pp. 5826 - 5839
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 04/2012, Volume 8, Issue 4, pp. 1440 - 1449
The importance of mesenchymal stem cells (MSC) in vascular regeneration is becoming increasingly recognized. However, few in vitro studies have been performed... 
Mesenchymal stem cell | Elasticity | Vascular differentiation | Nanofiber | 3-D matrix | HYDROGELS | MATERIALS SCIENCE, BIOMATERIALS | STIFFNESS | ENGINEERING, BIOMEDICAL | EXTRACELLULAR-MATRIX | SCAFFOLDS | Cross-Linking Reagents - pharmacology | Up-Regulation - radiation effects | Tensile Strength - drug effects | Elastic Modulus - drug effects | Polyethylene Glycols - chemistry | Methacrylates - chemistry | Spectroscopy, Fourier Transform Infrared | Tissue Scaffolds - chemistry | Polymerization - drug effects | Mesenchymal Stromal Cells - cytology | Ultraviolet Rays | Time Factors | Polymerase Chain Reaction | Compressive Strength - drug effects | Compressive Strength - radiation effects | Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology | Porosity - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Biomarkers - metabolism | Cell Differentiation - radiation effects | Nanofibers - chemistry | Mesenchymal Stromal Cells - drug effects | Nanofibers - ultrastructure | Polymerization - radiation effects | Endothelial Cells - metabolism | Mesenchymal Stromal Cells - metabolism | Rats | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Elasticity - drug effects | Endothelial Cells - radiation effects | Materials Testing | Elasticity - radiation effects | Muscle, Smooth, Vascular - cytology | Tensile Strength - radiation effects | Porosity - radiation effects | Elastic Modulus - radiation effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Animals | Cell Differentiation - drug effects | Endothelial Cells - cytology | Gene Expression Regulation - radiation effects | Endothelial Cells - drug effects | Actin | Polyethylene glycol | Stem cells | Smooth muscle | Muscle proteins | Polyols | Nanotechnology | Endothelium | Index Medicus | mesenchymal stem cell | vascular differentiation | 3D matrix | nanofiber
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2009, Volume 5, Issue 3, pp. 298 - 309
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2014, Volume 19, Issue 1, pp. 96 - 108
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) regulates metabolic genes in skeletal muscle and... 
SKELETAL-MUSCLE | PPAR-ALPHA | MITOCHONDRIAL UNCOUPLING PROTEIN | INSULIN-RESISTANCE | COACTIVATOR PGC-1 | IN-VIVO | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | LIVER-DISEASE | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | CELL BIOLOGY | Organ Specificity - drug effects | Transcription, Genetic - drug effects | Metabolic Diseases - pathology | Adipocytes, Brown - metabolism | Humans | Adipose Tissue, White - metabolism | Cardiovascular Diseases - pathology | Organ Specificity - genetics | Adipocytes, White - drug effects | Adipose Tissue, White - cytology | Exercise | Liver - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Oxidation-Reduction - drug effects | Weight Gain - drug effects | Physical Conditioning, Animal | Aminoisobutyric Acids - pharmacology | Induced Pluripotent Stem Cells - metabolism | Adipocytes, Brown - pathology | Glucose Tolerance Test | Cardiovascular Diseases - metabolism | Induced Pluripotent Stem Cells - drug effects | Adipocytes, Brown - drug effects | Liver - metabolism | Risk Factors | Aminoisobutyric Acids - blood | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Adipose Tissue, Brown - cytology | Phenotype | Adipocytes, White - pathology | Animals | Metabolic Diseases - metabolism | Cell Differentiation - drug effects | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | PPAR alpha - metabolism | Adipocytes, White - metabolism | Adipose Tissue, White - drug effects | Index Medicus
Journal Article