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Journal Article
Nature Medicine, ISSN 1078-8956, 11/2010, Volume 16, Issue 11, pp. 1299 - 1304
Bitter taste receptors (TAS2Rs) on the tongue probably evolved to evoke signals for avoiding ingestion of plant toxins. We found expression of TAS2Rs on human... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | CONTRACTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXATION | CELL BIOLOGY | HETEROGENEITY | LACTONES | ASTHMA | CHANNELS | MAMMALIAN TASTE | EXPRESSION | SPARKS | Asthma - metabolism | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Bronchi - physiopathology | Myocytes, Smooth Muscle - pathology | RNA, Messenger - metabolism | Airway Obstruction - metabolism | Bronchi - drug effects | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Muscle Relaxation - physiology | Bronchoconstriction - drug effects | Bronchi - metabolism | Bronchi - pathology | Myocytes, Smooth Muscle - metabolism | Membrane Potentials - drug effects | Bronchoconstriction - physiology | Asthma - physiopathology | Cell Separation | RNA, Messenger - genetics | Airway Obstruction - physiopathology | Muscle, Smooth - metabolism | Membrane Potentials - physiology | Taste - physiology | Gene Expression Regulation - drug effects | Animals | Taste - drug effects | Asthma - complications | Calcium Signaling - drug effects | Airway Obstruction - pathology | Muscle, Smooth - physiopathology | Mice | Receptors, G-Protein-Coupled - genetics | Muscle Relaxation - drug effects | Muscle, Smooth - pathology | Saccharin - pharmacology | Taste buds | Care and treatment | Usage | Animal models in research | Physiological aspects | Smooth muscle | Genetic aspects | Airway obstruction (Medicine) | Research | Risk factors | Signal transduction | Taste | Calcium | Cellular biology | Respiratory diseases
Journal Article
Circulation, ISSN 0009-7322, 05/2009, Volume 119, Issue 19, pp. 2578 - 2586
Journal Article
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 01/2016, Volume 356, Issue 1, pp. 53 - 63
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0131582
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2012, Volume 303, Issue 11, pp. 956 - 966
Activation of taste receptors (TAS2Rs) by bitter taste agonists has been reported to cause bronchodilation. The aim of this study was to extend the information... 
Bronchodilation | Prostaglandins | Airway smooth muscle | Asthma | ACTIVATION | PHYSIOLOGY | POTASSIUM CHANNELS | INDUCED BRONCHODILATION | airway smooth muscle | asthma | ANTAGONISM | RESPONSES | BK CHANNELS | TONE | RESPIRATORY SYSTEM | OBSTRUCTION | prostaglandins | bronchodilation | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Respiratory Mucosa - drug effects | Receptors, G-Protein-Coupled - metabolism | Albuterol - pharmacology | Male | Trachea - drug effects | Large-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | Trachea - metabolism | Receptors, G-Protein-Coupled - agonists | Chloroquine - pharmacology | Muscle, Smooth - drug effects | Large-Conductance Calcium-Activated Potassium Channels - physiology | Charybdotoxin - pharmacology | Trachea - physiology | Indoles - pharmacology | Muscle, Smooth - physiology | Cholinergic Agonists - pharmacology | Gene Expression | Guinea Pigs | Bronchodilator Agents - pharmacology | Indomethacin - pharmacology | Peptides - pharmacology | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Receptors, G-Protein-Coupled - genetics | Muscle Relaxation - drug effects | In Vitro Techniques | Quaternary Ammonium Compounds - pharmacology | Physiological aspects | Taste | Genetic aspects | Research | Drug therapy | Trachea | Bronchodilator agents
Journal Article
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2014, Volume 740, Issue Jul 15, pp. 302 - 311
Journal Article