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1. Full Text Consensus Statement for Standard of Care in Spinal Muscular Atrophy
by Wang, Ching H and Finkel, Richard S and Bertini, Enrico S and Schroth, Mary and Simonds, Anita and Wong, Brenda and Aloysius, Annie and Morrison, Leslie and Main, Marion and Crawford, Thomas O and Trela, Anthony and Participants of the International Conference on SMA Standard of Care
Journal of child neurology, ISSN 0883-0738, 08/2007, Volume 22, Issue 8, pp. 1027 - 1049
Standard of care | Consensus statement | Spinal muscular atrophy | Muscular Atrophy, Spinal - diagnosis | Postoperative Complications - etiology | Gastrointestinal Diseases - physiopathology | Humans | Gastrointestinal Diseases - etiology | Postoperative Complications - prevention & control | Respiratory Insufficiency - etiology | Respiratory Paralysis - therapy | Respiratory Paralysis - physiopathology | Deglutition Disorders - therapy | Child Nutrition Disorders - etiology | Respiratory Paralysis - etiology | Child Nutrition Disorders - physiopathology | Gait Disorders, Neurologic - physiopathology | Child Nutrition Disorders - prevention & control | Deglutition Disorders - etiology | Child | Deglutition Disorders - physiopathology | Respiratory Insufficiency - physiopathology | Diagnosis, Differential | Gastrointestinal Diseases - therapy | Respiratory Insufficiency - therapy | Consensus | Gait Disorders, Neurologic - therapy | Muscular Atrophy, Spinal - therapy | Muscular Atrophy, Spinal - complications | Gait Disorders, Neurologic - etiology | Index Medicus
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2. Full Text Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
by Mendell, Jerry R and Al-Zaidy, Samiah and Shell, Richard and Arnold, W. Dave and Rodino-Klapac, Louise R and Prior, Thomas W and Lowes, Linda and Alfano, Lindsay and Berry, Katherine and Church, Kathleen and Kissel, John T and Nagendran, Sukumar and L’Italien, James and Sproule, Douglas M and Wells, Courtney and Cardenas, Jessica A and Heitzer, Marjet D and Kaspar, Allan and Kaspar, Brian K and Corcoran, Sarah and Braun, Lyndsey and Likhite, Shibi and Miranda, Carlos and Meyer, Kathrin and Foust, K.D and Burghes, Arthur H.M
The New England journal of medicine, ISSN 0028-4793, 11/2017, Volume 377, Issue 18, pp. 1713 - 1722
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Spinal Muscular Atrophies of Childhood - genetics | Humans | Infant | Male | Dependovirus | Respiration, Artificial | Spinal Muscular Atrophies of Childhood - therapy | Disease-Free Survival | Liver Diseases - etiology | Survival of Motor Neuron 1 Protein - genetics | Female | Spinal Muscular Atrophies of Childhood - physiopathology | Historically Controlled Study | Infusions, Intravenous | Genetic Vectors | Nutritional Support | Motor Skills | Infant, Newborn | Cohort Studies | Genetic Therapy - adverse effects | Neuromuscular diseases | Intravenous administration | Cell survival | Gene transfer | Neurons | SMN protein | Nervous system | Patients | Children & youth | Spinal muscular atrophy | Proteins | Motor neuron diseases | Children | Gene therapy | Neuromuscular system | Prednisolone | Age | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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3. Full Text Cellular and molecular mechanisms of muscle atrophy
by Bonaldo, Paolo and Sandri, Marco
Disease models & mechanisms, ISSN 1754-8403, 01/2013, Volume 6, Issue 1, pp. 25 - 39
Pathology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cytokines - metabolism | Muscular Atrophy - metabolism | Signal Transduction | Humans | Muscular Atrophy - pathology | Ubiquitin - metabolism | Homeostasis | Mice, Transgenic | Muscle, Skeletal - metabolism | Muscular Atrophy - genetics | Autophagy | Mice, Knockout | Animals | Lysosomes - metabolism | Models, Biological | Inflammation Mediators - metabolism | Muscle Proteins - metabolism | Mice | Muscle, Skeletal - pathology | Myostatin - metabolism | Proteasome Endopeptidase Complex - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Muscular Atrophy - etiology | Index Medicus | Review
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4. Full Text Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy
by Wishart, Thomas M and Mutsaers, Chantal A and Riessland, Markus and Reimer, Michell M and Hunter, Gillian and Hannam, Marie L and Eaton, Samantha L and Fuller, Heidi R and Roche, Sarah L and Somers, Eilidh and Morse, Robert and Young, Philip J and Lamont, Douglas J and Hammerschmidt, Matthias and Joshi, Anagha and Hohenstein, Peter and Morris, Glenn E and Parson, Simon H and Skehel, Paul A and Becker, Thomas and Robinson, Iain M and Becker, Catherina G and Wirth, Brunhilde and Gillingwater, Thomas H
The Journal of clinical investigation, ISSN 0021-9738, 04/2014, Volume 124, Issue 4, pp. 1821 - 1834
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Spinal Cord - metabolism | Alternative Splicing | Humans | Ubiquitin - metabolism | Homeostasis | Muscle, Skeletal - metabolism | RNA, Messenger - metabolism | Muscular Atrophy, Spinal - genetics | Isoenzymes - metabolism | Mice, Mutant Strains | Survival of Motor Neuron 1 Protein - genetics | Disease Models, Animal | Ubiquitin-Activating Enzymes - genetics | Muscular Atrophy, Spinal - metabolism | Signal Transduction | Isoenzymes - genetics | Drosophila | RNA, Messenger - genetics | Rats | Mice, Transgenic | Zebrafish | Survival of Motor Neuron 1 Protein - metabolism | Muscular Atrophy, Spinal - etiology | Ubiquitin-Activating Enzymes - metabolism | beta Catenin - metabolism | Mice, Knockout | Animals | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Mice | Index Medicus | Abridged Index Medicus
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5. Full Text Advanced glycation end‐products induce skeletal muscle atrophy and dysfunction in diabetic mice via a RAGE‐mediated, AMPK‐down‐regulated, Akt pathway
by Chiu, Chen‐Yuan and Yang, Rong‐Sen and Sheu, Meei‐Ling and Chan, Ding‐Cheng and Yang, Ting‐Hua and Tsai, Keh‐Sung and Chiang, Chih‐Kang and Liu, Shing‐Hwa
The Journal of pathology, ISSN 0022-3417, 02/2016, Volume 238, Issue 3, pp. 470 - 482
advanced glycation end‐products | alagebrium chloride | diabetic myopathy | advanced glycation end-products | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | AMP-Activated Protein Kinases - metabolism | MAP Kinase Signaling System - physiology | Humans | Atrophy - pathology | Male | Case-Control Studies | Muscular Diseases - etiology | Muscle Proteins - metabolism | Muscle Weakness - pathology | Diabetes Mellitus - etiology | Muscle Fatigue - physiology | Muscle Weakness - etiology | Down-Regulation | Muscular Diseases - pathology | SKP Cullin F-Box Protein Ligases - metabolism | Atrophy - etiology | Muscle, Skeletal - physiology | Regeneration - physiology | Animals | Diabetes Mellitus, Experimental - etiology | Glycation End Products, Advanced - metabolism | Muscle Fibers, Skeletal - pathology | Receptor for Advanced Glycation End Products - physiology | Signal Transduction - physiology | Aged | Mice | Thiazoles - pharmacology | Muscle, Skeletal - pathology | Muscles | Health aspects | Diabetes | Index Medicus
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6. Full Text Oxidative stress and disuse muscle atrophy: cause or consequence?
by Powers, Scott K and Smuder, Ashley J and Judge, Andrew R
Current opinion in clinical nutrition and metabolic care, ISSN 1363-1950, 05/2012, Volume 15, Issue 3, pp. 240 - 245
Antioxidants | Oxidants | Calpain | Caspase-3 | Muscle protein synthesis | Proteasome | Reactive oxygen species rebox | Endocrinology & Metabolism | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Muscular Disorders, Atrophic - metabolism | Muscular Disorders, Atrophic - complications | Reactive Oxygen Species - metabolism | Muscular Atrophy - metabolism | Oxidative Stress | Signal Transduction | Humans | Muscular Atrophy - pathology | Muscle, Skeletal - metabolism | Proteolysis | Muscle Proteins - metabolism | Muscular Disorders, Atrophic - pathology | Muscle, Skeletal - pathology | Muscular Atrophy - etiology | Index Medicus | muscle protein synthesis | proteasome | calpain | antioxidants | reactive oxygen species | oxidants | redox | caspase-3
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7. Full Text Emerging therapies and challenges in spinal muscular atrophy
by Farrar, Michelle A and Park, Susanna B and Vucic, Steve and Carey, Kate A and Turner, Bradley J and Gillingwater, Thomas H and Swoboda, Kathryn J and Kiernan, Matthew C
Annals of neurology, ISSN 0364-5134, 03/2017, Volume 81, Issue 3, pp. 355 - 368
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Muscular Atrophy, Spinal - genetics | Animals | Muscular Atrophy, Spinal - etiology | Humans | Muscular Atrophy, Spinal - therapy | Medical screening | Index Medicus | Reviews | Review
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8. Full Text Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
by Sandri, Marco and Sandri, Claudia and Gilbert, Alex and Skurk, Carsten and Calabria, Elisa and Picard, Anne and Walsh, Kenneth and Schiaffino, Stefano and Lecker, Stewart H and Goldberg, Alfred L
Cell (Cambridge), ISSN 0092-8674, 04/2004, Volume 117, Issue 3, pp. 399 - 412
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ligases - genetics | Protein-Serine-Threonine Kinases | Muscle, Skeletal - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Muscle Cells - enzymology | SKP Cullin F-Box Protein Ligases | Muscle Proteins | RNA Interference | Glucocorticoids - metabolism | Cloning, Molecular | Adenoviridae - genetics | Fasting - metabolism | Muscular Atrophy - etiology | Proto-Oncogene Proteins - metabolism | Promoter Regions, Genetic | Muscular Atrophy - metabolism | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Ligases - metabolism | Muscular Atrophy - genetics | Transcription Factors - genetics | Proto-Oncogene Proteins c-akt | Transcription Factors - metabolism | Animals | Models, Biological | Mice | Muscle, Skeletal - pathology | Genetic Vectors | Insulin-Like Growth Factor I - metabolism | Ligases | Analysis | Genetic transcription | Index Medicus
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