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ChemBioChem, ISSN 1439-4227, 07/2017, Volume 18, Issue 13, pp. 1155 - 1171
About 2–3 million years ago, Alu‐mediated deletion of a critical exon in the CMAH gene became fixed in the hominin lineage ancestral to humans, possibly... 
diseases | Homo sapiens | sialic acids | evolution | CMAH | CHEMISTRY, MEDICINAL | DEAMINATED NEURAMINIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN XENO-AUTOANTIBODIES | NONHUMAN SIALIC-ACID | 1ST 2 STEPS | BIFUNCTIONAL ENZYME CATALYZES | HANGANUTZIU-DEICHER ANTIGEN | VERTEBRATE AMINO-SUGARS | ACYL SIDE-CHAIN | ERYTHROCYTE BINDING ANTIGEN | DUCHENNE MUSCULAR-DYSTROPHY | Mixed Function Oxygenases - deficiency | Neoplasms - metabolism | Humans | Hearing Loss - immunology | Autoantibodies - biosynthesis | Muscular Dystrophies - genetics | Hearing Loss - metabolism | Neoplasms - genetics | Muscular Dystrophies - immunology | Neuraminic Acids - immunology | Gene Expression | Disease Susceptibility | Muscular Dystrophies - metabolism | Insulin Resistance | Neuraminic Acids - chemistry | Pan troglodytes | Hearing Loss - pathology | Muscular Dystrophies - pathology | Mixed Function Oxygenases - immunology | Biological Evolution | Hearing Loss - genetics | Animals | Neoplasms - immunology | Neuraminic Acids - metabolism | Mice | Mutation | Genome | Mixed Function Oxygenases - genetics | Neoplasms - pathology | Human evolution | Physiological aspects | Analysis | Chimpanzees | Antibodies | Gene deletion | Inactivation | Muscular dystrophy | Meat | Ethics | Clonal deletion | Primates | Deletion | Immune system | Pathogens | Hunting | Wound healing | Deactivation | Reproductive isolation | Inflammation | Sialic acids | Insulin | Hearing loss | Acids | Healing | Dystrophy | Cancer
Journal Article
Human Gene Therapy, ISSN 1043-0342, 06/2017, Volume 28, Issue 6, pp. 493 - 509
Use of adeno-associated virus (AAV) to transduce genes into skeletal muscles can be associated with T-cell responses to viral capsid and/or to transgenic... 
Research Articles | gene therapy | muscular dystrophy | PD1 | neuromuscular junction | AAV | lymphocyte | CT GALNAC TRANSFERASE | GLUCOCORTICOID TREATMENT | MEDICINE, RESEARCH & EXPERIMENTAL | MEDIATED GENE-TRANSFER | DEFICIENT MICE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | VASCULAR DELIVERY | IMMUNE-RESPONSES | HEMOPHILIA-B | MOUSE MODEL | FACTOR-IX | GENETICS & HEREDITY | DUCHENNE MUSCULAR-DYSTROPHY | Dependovirus - genetics | CD8-Positive T-Lymphocytes - pathology | Genetic Vectors - administration & dosage | Muscular Dystrophies - therapy | Macaca mulatta | Muscular Dystrophies - genetics | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Immunity, Cellular - drug effects | Muscle, Skeletal - immunology | Muscle, Skeletal - drug effects | Muscular Dystrophies - immunology | N-Acetylgalactosaminyltransferases - genetics | Cell Death | Capsid Proteins - immunology | Transgenes | Immunosuppressive Agents - pharmacology | Programmed Cell Death 1 Ligand 2 Protein - agonists | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - immunology | Administration, Oral | Programmed Cell Death 1 Ligand 2 Protein - genetics | Programmed Cell Death 1 Receptor - agonists | Dependovirus - immunology | Injections, Intramuscular | Muscular Dystrophies - pathology | Programmed Cell Death 1 Ligand 2 Protein - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | CD8-Positive T-Lymphocytes - drug effects | N-Acetylgalactosaminyltransferases - immunology | Prednisone - pharmacology | Muscle, Skeletal - pathology | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - genetics | Capsid Proteins - genetics | Genetic Therapy - methods | Injections, Intra-Arterial | Gene transfer | Immunoregulation | CD8 antigen | Mortality | Transgenic | Antibodies | Muscles | Caspase | Viruses | Lymphocytes T | Prednisone | Caspase-3 | Skeletal muscle | Proteins | Musculoskeletal system | Lymphocytes | Cell death | Foxp3 protein | Ligands | Infiltration | Apoptosis
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