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Journal of Clinical Investigation, ISSN 0021-9738, 06/2014, Volume 124, Issue 6, pp. 2651 - 2667
Duchenne muscular dystrophy (DMD) is caused by mutations in the gene encoding dystrophin, which results in dysfunctional signaling pathways within muscle.... 
MEDICINE, RESEARCH & EXPERIMENTAL | SKELETAL-MUSCLE | MDX MOUSE | MESSENGER-RNAS | CENTRONUCLEAR MYOPATHY | GLYCOPROTEIN COMPLEX | C2C12 MYOBLAST | TUMOR-SUPPRESSOR | CELL-PROLIFERATION | MYOBLAST FUSION | PROTEIN-KINASE B | Muscular Dystrophy, Animal - genetics | Up-Regulation | Humans | Male | MicroRNAs - metabolism | Muscle, Skeletal - metabolism | Muscle Fibers, Skeletal - metabolism | Muscular Dystrophy, Animal - pathology | Guanine Nucleotide Exchange Factors - metabolism | Base Sequence | Mice, Inbred mdx | Muscular Dystrophy, Animal - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Mice, Inbred C57BL | PTEN Phosphohydrolase - metabolism | Mice, Transgenic | Muscular Dystrophy, Duchenne - pathology | Nerve Tissue Proteins - genetics | Sequence Homology, Nucleic Acid | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Muscle Fibers, Skeletal - pathology | Mice | MicroRNAs - genetics | Muscular Dystrophy, Duchenne - metabolism | Muscle, Skeletal - pathology | Muscular Dystrophy, Duchenne - genetics | MicroRNA | Cellular signal transduction | Genetic aspects | Diagnosis | Properties | Genetic regulation | Muscular dystrophy | Muscular system | Mutation | Rodents | Index Medicus | Abridged Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16105 - 16105
Journal Article
Journal Article
Science Signaling, ISSN 1945-0877, 08/2012, Volume 5, Issue 236, pp. ra56 - ra56
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 9/2011, Volume 333, Issue 6048, pp. 1440 - 1445
We report that in heart cells, physiologic stretch rapidly activates reduced-form nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2) to... 
Reactive oxygen species | Quantification | Microtubules | Duchenne muscular dystrophy | REPORTS | Fluorescence | Myocardium | Cardiomyopathies | Physiological regulation | T tests | Heart diseases | NADPH OXIDASE | PRESSURE | CALCIUM SPARKS | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | VENTRICULAR MYOCYTES | AXIAL STRETCH | INHIBITOR | FAILURE | RETICULUM CA2+ LEAK | MDX MICE | Electric Stimulation | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Calcium - metabolism | Muscular Dystrophy, Animal - physiopathology | NADPH Oxidases - metabolism | Ryanodine Receptor Calcium Release Channel - metabolism | Microtubules - metabolism | Membrane Glycoproteins - antagonists & inhibitors | Mice, Inbred mdx | Muscular Dystrophy, Animal - metabolism | Sarcoplasmic Reticulum - metabolism | Sarcolemma - metabolism | Calcium Signaling | Myocardial Contraction | Oxidation-Reduction | Signal Transduction | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Rats | NADPH Oxidase 2 | Rats, Sprague-Dawley | Mechanotransduction, Cellular | Animals | Myocytes, Cardiac - physiology | Myocytes, Cardiac - metabolism | Mice | Physiological aspects | Calcium channels | Cellular signal transduction | Research | Properties | Heart cells | Heart | Signal transduction | Enzymes | Cardiomyocytes | Biochemistry | Cellular biology | Index Medicus | Phosphates | Receptors | Sarcoplasmic reticulum | Oxidase | Nicotinamide adenine dinucleotide | Bursting | Tuning
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 49, pp. 19183 - 19187
The overlapping histological and biochemical features underlying the beneficial effect of deacetylase inhibitors and NO donors in dystrophic muscles suggest an... 
Artificial satellites | Duchenne muscular dystrophy | Muscles | Small interfering RNA | Histones | Oxides | Muscular dystrophies | Pharmacology | Skeletal muscle | Myoblasts | Epigenetic | RECRUITMENT | COMPLEX | SKELETAL-MUSCLE MASS | FUSION | epigenetic | MULTIDISCIPLINARY SCIENCES | INDUCTION | MDX MICE | SYNTHASE | SIGNALING PATHWAY | GENE-EXPRESSION | skeletal muscle | FOLLISTATIN | Muscular Dystrophy, Animal - drug therapy | Epigenesis, Genetic | Muscle, Skeletal - cytology | Muscular Dystrophy, Animal - pathology | Repressor Proteins - antagonists & inhibitors | Mice, Inbred mdx | Muscular Dystrophy, Animal - metabolism | Myoblasts - cytology | Benzamides - pharmacology | Repressor Proteins - metabolism | Nitrogen - metabolism | Histone Deacetylases - genetics | Muscular Dystrophy, Duchenne - drug therapy | Mice, Inbred C57BL | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Repressor Proteins - genetics | Histone Deacetylase 2 | Histone Deacetylases - metabolism | Muscular Dystrophy, Duchenne - pathology | Satellite Cells, Skeletal Muscle - enzymology | Animals | Histone Deacetylase Inhibitors | Mice | Muscular Dystrophy, Duchenne - metabolism | Pyridines - pharmacology | RNA, Small Interfering | Nitric Oxide - metabolism | Myoblasts - enzymology | Musculoskeletal system | Biochemistry | Mutation | Gene expression | Rodents | Nitric oxide