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Metabolic bone disease & related research, ISSN 0221-8747, 1984
Journal
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7519 - 12
In silico network-based methods have shown promising results in the field of drug development. Yet, most of networks used in the previous research have not... 
SYSTEM | DATABASE | RENIN | GENE | PATHWAY | MULTIDISCIPLINARY SCIENCES | TISSUE | KEGG | NEBIVOLOL | HYPERTENSION | BLOOD-PRESSURE | Hematologic Diseases - pathology | Liver - pathology | Metabolic Diseases - pathology | Respiratory Tract Diseases - metabolism | Kidney - pathology | Skin - metabolism | Hematologic Diseases - metabolism | Humans | Muscle, Skeletal - metabolism | Respiratory Tract Diseases - drug therapy | Respiratory Tract Diseases - genetics | Brain - metabolism | Musculoskeletal Diseases - pathology | Kidney - metabolism | Liver - drug effects | Muscle, Skeletal - drug effects | Myocardium - metabolism | Nervous System Diseases - metabolism | Nutrition Disorders - pathology | Computational Biology - methods | Kidney - drug effects | Liver - metabolism | Nervous System Diseases - drug therapy | Connective Tissue Diseases - metabolism | Neoplasms - drug therapy | Brain - drug effects | Connective Tissue Diseases - drug therapy | Connective Tissue Diseases - pathology | Lung - drug effects | Brain - pathology | Hematologic Diseases - genetics | Prescription Drugs - pharmacokinetics | Digestive System Diseases - pathology | Neoplasms - metabolism | Cardiovascular Diseases - drug therapy | Drugs, Investigational - pharmacokinetics | Respiratory Tract Diseases - pathology | Hematologic Diseases - drug therapy | Metabolic Diseases - drug therapy | Cardiovascular Diseases - pathology | Nervous System Diseases - genetics | Cardiovascular Diseases - genetics | Musculoskeletal Diseases - genetics | Neoplasms - genetics | Lung - metabolism | Skin - pathology | Nervous System Diseases - pathology | Lung - pathology | Musculoskeletal Diseases - drug therapy | Cardiovascular Diseases - metabolism | Musculoskeletal Diseases - metabolism | Nutrition Disorders - drug therapy | Nutrition Disorders - genetics | Myocardium - pathology | Organ Specificity | Digestive System Diseases - genetics | Algorithms | Digestive System Diseases - drug therapy | Nutrition Disorders - metabolism | Metabolic Diseases - metabolism | Digestive System Diseases - metabolism | Metabolic Diseases - genetics | Connective Tissue Diseases - genetics | Muscle, Skeletal - pathology | Neoplasms - pathology | Skin - drug effects | Drug development | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2008, Volume 105, Issue 13, pp. 5266 - 5270
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9560 - 9565
The SNP (c.1142G > A;p.R381Q) in the IL-23 receptor (IL23R) confers protection from multiple inflammatory diseases, representing one of the most significant... 
T lymphocytes | Receptors | Cytokines | HEK293 cells | Secretion | Memory | Cell lines | HeLa cells | Inflammation | Cells | Crohn's disease | Psoriasis | Ulcerative colitis | MULTIDISCIPLINARY SCIENCES | DISTINCT | INTERLEUKIN-23 | CYTOKINE | IL-23 | BOWEL-DISEASE | INTESTINAL INFLAMMATION | psoriasis | IL-17 | HUMAN TH17 CELLS | cytokines | ulcerative colitis | DIFFERENTIATION | GENOME-WIDE ASSOCIATION | Luciferases - metabolism | Humans | Inflammatory Bowel Diseases - immunology | Interleukin-17 - immunology | Immunoblotting | Interferon-gamma - metabolism | Inflammatory Bowel Diseases - metabolism | Interleukins - metabolism | Luciferases - genetics | CD4-Positive T-Lymphocytes - immunology | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Th17 Cells - drug effects | Flow Cytometry | Th17 Cells - metabolism | Interleukins - immunology | HEK293 Cells | Inflammatory Bowel Diseases - genetics | CD8-Positive T-Lymphocytes - metabolism | Polymorphism, Single Nucleotide - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Receptors, Interleukin - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Receptors, Interleukin - genetics | Interleukin-17 - metabolism | Interleukin-23 - pharmacology | Signal Transduction - drug effects | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Th17 Cells - immunology | Cell Proliferation - drug effects | HeLa Cells | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | Signal transduction | Genetics | T cell receptors | Inflammatory diseases | Polymorphism | Index Medicus | Autoimmunity | Transcription | CD8 antigen | Helper cells | Stat3 protein | Interleukin 22 | Interleukin 23 | Lymphocytes T | Single-nucleotide polymorphism | Gene polymorphism | Interleukin 17 | CD4 antigen | Cell activation | Arginine | Autoimmune diseases | Glutamine | Biological Sciences
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 08/2014, Volume 73, Issue 8, pp. 1522 - 1528
Objective The primary objective of this prospective case-control study was to assess the diagnostic value of several intra-articular and periarticular... 
ASYMPTOMATIC METATARSOPHALANGEAL JOINTS | TOPHI | TASK-FORCE | SYNOVIAL-FLUID | DISEASE | EVIDENCE BASED RECOMMENDATIONS | PART II | RHEUMATOLOGY | SONOGRAPHIC ASSESSMENT | ULTRASONOGRAPHY | HYALINE CARTILAGE | Metacarpal Bones - metabolism | Prospective Studies | Humans | Middle Aged | Male | Case-Control Studies | Uric Acid - chemistry | Reference Standards | Metacarpal Bones - diagnostic imaging | Cartilage, Articular - metabolism | Tendons - diagnostic imaging | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Metatarsal Bones - diagnostic imaging | Joints - metabolism | Ultrasonography - methods | Cartilage, Articular - diagnostic imaging | Musculoskeletal Diseases - etiology | Reproducibility of Results | Ultrasonography - statistics & numerical data | Uric Acid - metabolism | Musculoskeletal Diseases - metabolism | Tendons - metabolism | Crystallization | Joints - diagnostic imaging | Metatarsal Bones - metabolism | Gout - diagnostic imaging | Gout - metabolism | Musculoskeletal Diseases - diagnostic imaging | Gout - complications | Aged | Observer Variation | Ultrasonography - standards | Musculoskeletal diseases | Usage | Care and treatment | Sensitivity analysis | Diagnosis | Ultrasonic waves | Studies | Validity | Ultrasonic imaging | Disease | Laboratories | Rheumatism | Arthritis | Agreements | Clinical medicine | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2016, Volume 11, Issue 2, pp. e0147818 - e0147818
Rhabdomyolysis is common in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) and other metabolic myopathies, but its pathogenic basis is poorly... 
SKELETAL-MUSCLE | MAGNETIC-RESONANCE-SPECTROSCOPY | ACID BETA-OXIDATION | MAXIMAL FAT OXIDATION | FATIGUE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | KINASE | RESISTANCE | DUCHENNE MUSCULAR-DYSTROPHY | MITOCHONDRIAL MYOPATHIES | Mitochondrial Diseases - pathology | Humans | Muscle Fibers, Fast-Twitch - metabolism | Mitochondrial Diseases - metabolism | Rhabdomyolysis - complications | Male | Muscle Fibers, Slow-Twitch - metabolism | Adenosine Triphosphate - biosynthesis | Case-Control Studies | Mitochondrial Diseases - complications | Exercise | Lipid Metabolism, Inborn Errors - pathology | Muscular Diseases - physiopathology | Rhabdomyolysis - pathology | Adult | Female | Lipid Metabolism, Inborn Errors - metabolism | Acyl-CoA Dehydrogenase, Long-Chain - metabolism | Muscular Diseases - metabolism | Oxidative Phosphorylation | Rhabdomyolysis - physiopathology | Mitochondria - metabolism | Muscular Diseases - pathology | Models, Statistical | Acetylcarnitine - blood | Rhabdomyolysis - metabolism | Lipid Metabolism, Inborn Errors - physiopathology | Phosphates - metabolism | Muscle Fibers, Slow-Twitch - pathology | Adolescent | Muscle Fibers, Fast-Twitch - pathology | Muscular Diseases - complications | Phosphocreatine - metabolism | Lipid Metabolism, Inborn Errors - complications | Mitochondrial Diseases - physiopathology | Acyl-CoA Dehydrogenase, Long-Chain - deficiency | Physiological aspects | Cycling | Research | Rhabdomyolysis | Risk factors | Phosphates | Pediatrics | Neurosciences | Nuclear magnetic resonance--NMR | Laboratories | Oxidative metabolism | Homeostasis | Chains | Dehydrogenase | Muscular dystrophy | Acyl-CoA dehydrogenase | Defects | Mitochondria | Child development | Energy | Metabolites | Rodents | Workloads | Mathematical models | Bioinformatics | Enzymes | Departments | Phosphorus | Phosphocreatine | Earth science | Metabolism | Medical screening | Patients | Fatty acids | Carnitine | Children & youth | Energy balance | Musculoskeletal system | Chemistry | Hypotheses | Hospitals | Bicycles | Quadriceps muscle | Respiration | ATP | Metabolic disorders | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 452 - 455
Journal Article
世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2014, Volume 20, Issue 26, pp. 8525 - 8534
AIM:To develop an animal model that encompasses the different facets of non-alcoholic steatohepatitis(NASH),which has been a challenge.METHODS:In this study,we... 
steatohepatitis | Gender | Non-alcoholic | differences | Gender differences | Inflammasome | Non-alcoholic steatohepatitis | High fat diet | FIBROSIS | CHOLESTEROL | CHRONIC HEPATITIS-C | NONALCOHOLIC STEATOHEPATITIS | LIVER-DISEASE | PATHOGENESIS | HEPATOCELLULAR-CARCINOMA | ANIMAL-MODELS | MICE | SEX-DIFFERENCES | GASTROENTEROLOGY & HEPATOLOGY | Tumor Necrosis Factor-alpha - metabolism | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Inflammasomes - metabolism | Actins - metabolism | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | Caspase 1 - metabolism | Male | Alanine Transaminase - blood | Insulin - blood | RNA, Messenger - metabolism | Actins - genetics | DNA-Binding Proteins - metabolism | Liver - immunology | Collagen Type I - genetics | Time Factors | Interleukin-1beta - metabolism | Inflammation Mediators - metabolism | Liver Cirrhosis - metabolism | Female | Chemokine CCL2 - metabolism | Weight Gain | Liver Cirrhosis - etiology | Procollagen - genetics | Collagen Type I - metabolism | Fructose - adverse effects | Non-alcoholic Fatty Liver Disease - genetics | Liver - metabolism | Mice, Inbred C57BL | Non-alcoholic Fatty Liver Disease - immunology | Insulin Resistance | Chemokine CCL2 - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Procollagen - metabolism | DNA-Binding Proteins - genetics | Inflammasomes - genetics | Animals | Inflammasomes - immunology | Sex Factors | Triglycerides - blood | Liver Cirrhosis - pathology | Dietary Sucrose - adverse effects | Blood Glucose - metabolism | Index Medicus | Original
Journal Article
Journal Article