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Mutation Research - Genetic Toxicology and Environmental Mutagenesis, ISSN 1383-5718, 08/2012, Volume 747, Issue 1, pp. 36 - 45
The Ames microplate format (MPF™) test, which uses liquid media and in 384-well microplates with a readout based on a colour-change, has been used for over 10... 
Ames pre-incubation test | Ames MPF test | Weak-positive compounds | Comparative study | STRAINS | ESCHERICHIA-COLI | SALMONELLA-TYPHIMURIUM TA102 | MUTAGENICITY | GENOTOXICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CARCINOGENICITY | GENETICS & HEREDITY | TOXICOLOGY | Index Medicus | Databases | Ames test | Mutagenesis | Genotoxicity | Agar | Mutagenicity | Drug development | Pharmaceuticals
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 06/2016, Volume 77, pp. 13 - 24
Journal Article
Journal Article
Toxicologic Pathology, ISSN 0192-6233, 6/2011, Volume 39, Issue 4, pp. 716 - 744
Journal Article
Nucleic Acid Therapeutics, ISSN 2159-3337, 12/2016, Volume 26, Issue 6, pp. 363 - 371
Registration of pharmaceuticals requires an assessment of their genotoxic potential using in vitro and in vivo tests outlined in the International Conference... 
genotoxicity | hPBL | micronucleus | siRNA-GalNAc conjugate | Ames | comet | MUTAGENS | MEDICINE, RESEARCH & EXPERIMENTAL | OUTER-MEMBRANE | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | OLIGONUCLEOTIDE | CARCINOGENS | Glycoconjugates - metabolism | Cricetulus | Glycoconjugates - chemistry | Humans | Glycoconjugates - pharmacology | Bone Marrow - physiology | Acetylgalactosamine - metabolism | Micronucleus Tests | RNA, Small Interfering - chemistry | Endocytosis | Lymphocytes - physiology | DNA Breaks, Double-Stranded - drug effects | Biotransformation | Mutagenicity Tests | Bone Marrow - drug effects | CHO Cells | RNA, Small Interfering - pharmacology | Rats | RNA Cleavage | Acetylgalactosamine - chemistry | Hep G2 Cells | Animals | Lymphocytes - drug effects | HeLa Cells | Primary Cell Culture | Acetylgalactosamine - pharmacology | RNA, Small Interfering - metabolism | Cell culture | Conjugates | N-Acetylgalactosamine | Media (culture) | DNA damage | Genotoxicity | Gram-positive bacteria | Antisense | Nucleotides | Kinases | Assaying | Dosage | Proteins | Biomedical materials | Transfection | Metabolites | E coli | Lymphocytes | Ribose | Peripheral blood | Cell cycle | Bone marrow | Biocompatibility | Bacteria | Phosphorothioate | Chromosomes | Deoxyribonucleic acid--DNA | Biodegradation | Mass spectroscopy | CD3 antigen | Exposure | siRNA | Organic chemistry | Bone mass | Ames test | Reagents | Lysis | Culture media | In vivo methods and tests | Lymphomas | Mutation | Laboratory animals | Mass spectrometry | Pharmaceuticals
Journal Article
Journal Article
Environmental Science and Pollution Research, ISSN 0944-1344, 11/2015, Volume 22, Issue 21, pp. 16358 - 16370
River sediments may contain a huge variety of environmental contaminants and play a key role in the ecological status of aquatic ecosystems. Contaminants... 
umuC test | Environmental Health | Sediment | Soxhlet extract | Ecotoxicology | Environment, general | Fish acute toxicity test | Ames test | Environment | Mutagenicity | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Luminescent bacteria test | Algae growth inhibition test | Environmental Chemistry | Atmospheric Protection/Air Quality Control/Air Pollution | Daphnia acute toxicity test | Lemna growth inhibition test | DREDGED MATERIAL | DANIO-RERIO | TESTS | FRESH-WATER SEDIMENTS | QUALITY | DANUBE RIVER | ELBE ESTUARY | RISK | EFFECT-DIRECTED ANALYSIS | CONTACT ASSAY | ENVIRONMENTAL SCIENCES | Microbial Viability - drug effects | Risk Assessment | Toxicity Tests, Acute - standards | Zebrafish | Lethal Dose 50 | Toxicity Tests, Acute - methods | Water Pollutants, Chemical - analysis | Salmonella typhimurium | Reference Standards | Animals | Water Pollutants, Chemical - toxicity | Aliivibrio fischeri | Chlorophyta | Rivers - chemistry | Daphnia | Geologic Sediments - chemistry | Analysis | Dimethyl sulfoxide | DNA polymerases | Bacteria | River sediments | Rivers | Batteries | Investigations | Contamination | Studies | Environmental science | Mutagenesis | Contaminated sediments | Biological assays | Index Medicus | Miljövetenskap | Geovetenskap och miljövetenskap | Naturvetenskap | Enviromental Science | Natural Sciences | Earth and Related Environmental Sciences | Environmental Sciences
Journal Article