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1. Full Text Myasthenia gravis: subgroup classification and therapeutic strategies
by Gilhus, Nils Erik, Prof and Verschuuren, Jan J, Prof
Lancet Neurology, The, ISSN 1474-4422, 2015, Volume 14, Issue 10, pp. 1023 - 1036
Summary Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and fatigue, is B-cell mediated, and is associated with antibodies... 
Neurology | PROTEIN 4 | INTRAVENOUS IMMUNOGLOBULIN | RYANODINE RECEPTOR ANTIBODIES | DOUBLE-BLIND | CLINICAL CHARACTERISTICS | RANDOMIZED-TRIAL | PLACEBO-CONTROLLED TRIAL | ACETYLCHOLINE-RECEPTOR | MYCOPHENOLATE-MOFETIL | CLINICAL NEUROLOGY | MUSCLE-SPECIFIC KINASE | Myasthenia Gravis - classification | Myasthenia Gravis - immunology | Myasthenia Gravis - drug therapy | Humans | Myasthenia gravis | Azathioprine | Health aspects | Analysis | Studies | Immunoglobulins | Autoimmune diseases | Rodents
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2. Full Text Randomized Trial of Thymectomy in Myasthenia Gravis
by Wolfe, Gil I and Kaminski, Henry J and Aban, Inmaculada B and Minisman, Greg and Kuo, Hui-Chien and Marx, Alexander and Ströbel, Philipp and Mazia, Claudio and Oger, Joel and Cea, J. Gabriel and Heckmann, Jeannine M and Evoli, Amelia and Nix, Wilfred and Ciafaloni, Emma and Antonini, Giovanni and Witoonpanich, Rawiphan and King, John O and Beydoun, Said R and Chalk, Colin H and Barboi, Alexandru C and Amato, Anthony A and Shaibani, Aziz I and Katirji, Bashar and Lecky, Bryan R.F and Buckley, Camilla and Vincent, Angela and Dias-Tosta, Elza and Yoshikawa, Hiroaki and Waddington-Cruz, Márcia and Pulley, Michael T and Rivner, Michael H and Kostera-Pruszczyk, Anna and Pascuzzi, Robert M and Jackson, Carlayne E and Garcia Ramos, Guillermo S and Verschuuren, Jan J.G.M and Massey, Janice M and Kissel, John T and Werneck, Lineu C and Benatar, Michael and Barohn, Richard J and Tandan, Rup and Mozaffar, Tahseen and Conwit, Robin and Odenkirchen, Joanne and Sonett, Joshua R and Jaretzki, Alfred and Newsom-Davis, John and Cutter, Gary R and MGTX Study Grp and MGTX Study Group
The New England Journal of Medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 6, pp. 511 - 522
In patients with nonthymomatous myasthenia gravis, thymectomy plus prednisone was associated with better clinical outcomes than prednisone alone. Patients... 
MEDICINE, GENERAL & INTERNAL | EXTENDED THYMECTOMY | THORACOSCOPIC THYMECTOMY | Severity of Illness Index | Single-Blind Method | Glucocorticoids - administration & dosage | Myasthenia Gravis - classification | Prednisone - administration & dosage | Humans | Middle Aged | Male | Treatment Outcome | Combined Modality Therapy | Hospitalization | Young Adult | Thymectomy | Adolescent | Adult | Female | Aged | Myasthenia Gravis - drug therapy | Myasthenia Gravis - surgery | Treatment outcome | Usage | Care and treatment | Myasthenia gravis | Analysis | Clinical trials | Prednisone | Dosage and administration | Lymphatic system | Neuromuscular diseases | Patients | Quality of life | Neurological diseases | Immunosuppression | Surgery | Neuromuscular junctions | Myasthenia | Azathioprine
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3. Full Text Myasthenia gravis: an update for the clinician
by Sieb, J. P
Clinical & Experimental Immunology, ISSN 0009-9104, 03/2014, Volume 175, Issue 3, pp. 408 - 418
Summary This paper provides a thorough overview of the current advances in diagnosis and therapy of myasthenia gravis (MG). Nowadays the term ‘myasthenia... 
myasthenia gravis | diagnostics | neuroimmunology | therapy/immunotherapy | Myasthenia gravis | Therapy/immunotherapy | Diagnostics | Neuroimmunology | therapy | IMMUNOLOGY | REFRACTORY MYASTHENIA | COMPLETE STABLE REMISSION | PLASMA-EXCHANGE | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | CELL-ACTIVATING FACTOR | NEUROMYELITIS-OPTICA | immunotherapy | DOUBLE-BLIND | ANTISENSE TREATMENT | ANTI-MUSK | MYCOPHENOLATE-MOFETIL | Myasthenia Gravis - epidemiology | Myasthenia Gravis - diagnosis | Myasthenia Gravis - drug therapy | Myasthenia Gravis - etiology | Humans | Autoimmune diseases | Medical prognosis | Immune system | Review
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4. Full Text Nivolumab-related myasthenia gravis with myositis and myocarditis in Japan
by Suzuki, Shigeaki and Ishikawa, Nobuhisa and Konoeda, Fumie and Seki, Nobuhiko and Fukushima, Satoshi and Takahashi, Kikuko and Uhara, Hisashi and Hasegawa, Yoshikazu and Inomata, Shinichiro and Otani, Yasushi and Yokota, Kenji and Hirose, Takashi and Tanaka, Ryo and Suzuki, Norihiro and Matsui, Makoto
Neurology, ISSN 0028-3878, 08/2017, Volume 89, Issue 11, pp. 1127 - 1134
OBJECTIVE:To report the clinical features of myasthenia gravis (MG) induced by treatment with immune checkpoint inhibitors using 2-year safety databases based... 
PATIENT | MELANOMA | EXACERBATION | CLINICAL NEUROLOGY | Myasthenia Gravis - complications | Myocarditis - chemically induced | Autoantibodies - blood | Humans | Immunosuppressive Agents - therapeutic use | Ipilimumab | Middle Aged | Myocarditis - drug therapy | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Myositis - chemically induced | Antineoplastic Agents - therapeutic use | Myositis - complications | Activities of Daily Living | Databases, Pharmaceutical | Neoplasms - blood | Antineoplastic Agents - adverse effects | Aged, 80 and over | Female | Myositis - drug therapy | Creatine Kinase - blood | Myasthenia Gravis - blood | Myocarditis - complications | Japan | Treatment Outcome | Biomarkers - blood | Myocarditis - blood | Myositis - blood | Myasthenia Gravis - chemically induced | Neoplasms - drug therapy | Nivolumab | Aged | Myasthenia Gravis - drug therapy
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5. Full Text Myasthenia gravis: from autoantibodies to therapy
by Mantegazza, Renato and Bernasconi, Pia and Cavalcante, Paola
Current opinion in neurology, ISSN 1350-7540, 10/2018, Volume 31, Issue 5, pp. 517 - 525
Purpose of review The current article reviews the recent advances in the field of myasthenia gravis, which span from autoantibody profiling and pathogenic... 
ANTIBODIES | treatment | CELLS | thymus | PROTEIN 4 | INCREASED EXPRESSION | MUSK | myasthenia gravis | PERIPHERAL-BLOOD | NEUROSCIENCES | CLINICAL NEUROLOGY | IMMUNIZATION | innate immunity | TARGETS | HAPLOTYPE | autoantibodies | RECEPTORS 7 | Autoimmunity | Autoantibodies - immunology | Phenotype | Humans | Immunosuppressive Agents - therapeutic use | Myasthenia Gravis - therapy | Myasthenia Gravis - immunology | Myasthenia Gravis - drug therapy | Precision Medicine | Drug therapy | Development and progression | Myasthenia gravis
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6. Full Text Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review
by Hehir, Michael K and Hobson-Webb, Lisa D and Benatar, Michael and Barnett, Carolina and Silvestri, Nicholas J and Howard, James F and Howard, Diantha and Visser, Amy and Crum, Brian A and Nowak, Richard and Beekman, Rachel and Kumar, Aditya and Ruzhansky, Katherine and Chen, I-Hweii Amy and Pulley, Michael T and LaBoy, Shannon M and Fellman, Melissa A and Greene, Shane M and Pasnoor, Mamatha and Burns, Ted M
Neurology, ISSN 0028-3878, 09/2017, Volume 89, Issue 10, pp. 1069 - 1077
OBJECTIVE:To evaluate the efficacy of rituximab in treatment of anti-muscle-specific kinase (MuSK) myasthenia gravis (MG). METHODS:This was a multicenter,... 
MANAGEMENT | CLINICAL FINDINGS | RECOMMENDATIONS | CLINICAL NEUROLOGY | Severity of Illness Index | Single-Blind Method | Autoantibodies - metabolism | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Receptor Protein-Tyrosine Kinases - immunology | Male | Treatment Outcome | Rituximab - therapeutic use | Anti-Inflammatory Agents - therapeutic use | Adult | Female | Receptors, Cholinergic - immunology | Myasthenia Gravis - immunology | Myasthenia Gravis - drug therapy | Prednisone - therapeutic use | Immunologic Factors - therapeutic use
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7. Full Text Myasthenia gravis: Past, present, and future
by Conti-Fine, Bianca M and Milani, Monica and Kaminski, Henry J
Journal of Clinical Investigation, ISSN 0021-9738, 11/2006, Volume 116, Issue 11, pp. 2843 - 2854
Myasthenia gravis (MG) is an autoimmune syndrome caused by the failure of neuromuscular transmission, which results from the binding of autoantibodies to... 
MEDICINE, RESEARCH & EXPERIMENTAL | MUSCLE ACETYLCHOLINE-RECEPTOR | IMMUNE-RESPONSE | INTERFERON-GAMMA | DENDRITIC CELLS | AUTOIMMUNE MYASTHENIA | TYROSINE KINASE MUSK | EXTRAOCULAR-MUSCLE | PLACEBO-CONTROLLED TRIAL | NEUROMUSCULAR-JUNCTION | CD4(+)CD25(+) T-CELLS | Lymphocytes - metabolism | History, 17th Century | Myasthenia Gravis - history | History, 21st Century | Receptors, Cholinergic - metabolism | Neuromuscular Junction - metabolism | History, 20th Century | Humans | Immunosuppressive Agents - therapeutic use | Myasthenia Gravis - diagnosis | Neuromuscular Junction - immunology | Animals | Lymphocytes - immunology | History, 19th Century | Receptors, Cholinergic - immunology | Myasthenia Gravis - immunology | Myasthenia Gravis - drug therapy | Neuromuscular Junction - pathology | Proteins | Autoimmunity | Autoantibodies | Myasthenia gravis | Protein binding | Science in Medicine
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8. Full Text Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
by Howard, James F and Utsugisawa, Kimiaki and Benatar, Michael and Murai, Hiroyuki and Barohn, Richard J and Illa, Isabel and Jacob, Saiju and Vissing, John and Burns, Ted M and Kissel, John T and Muppidi, Srikanth and Nowak, Richard J and O'Brien, Fanny and Wang, Jing-Jing and Mantegazza, Renato and Mazia, Claudio Gabriel and Wilken, Miguel and Ortea, Carolina and Saba, Juliet and Rugiero, Marcelo and Bettini, Mariela and Vidal, Gonzalo and Vidal, Nuria and Garcia, Rebekah and Garcia, Sonia and Garcia, Alejandra Dalila and Lamont, Phillipa and Leong, Wai-Kuen and Boterhoven, Heidi and Fyfe, Beverly and Roberts, Leslie and Jasinarachchi, Mahi and Willlems, Natasha and Wanschitz, Julia and Löscher, Wolfgang and De Bleecker, Jan and Van den Abeele, Guy and de Koning, Kathy and De Mey, Katrien and Mercelis, Rudy and Wagemaekers, Linda and Mahieu, Delphine and Van Damme, Philip and Smetcoren, Charlotte and Stevens, Olivier and Verjans, Sarah and D'Hondt, Ann and Tilkin, Petra and Alves de Siqueira Carvalho, Alzira and Hasan, Rosa and Dias Brockhausen, Igor and Feder, David and Ambrosio, Daniel and Melo, Ana Paula and Rocha, Rosana and Rosa, Bruno and Veiga, Thabata and Augusto da Silva, Luiz and Gonçalves Geraldo, Jordana and da Penha Morita Ananias, Maria and Nogueira Coelho, Erica and Paiva, Gabriel and Pozo, Marina and Prando, Natalia and Dada Martineli Torres, Debora and Fernanda Butinhao, Cristiani and Coelho, Erica and Renata Cubas Volpe, Luciana and Duran, Gustavo and Gomes da Silva, Tamires Cristina and Otavio Maia Gonçalves, Luiz and Pazetto, Lucas Eduardo and Souza Duca, Luciana and Suriane Fialho, Tomás Augusto and Gheller Friedrich, Maurício André and Guerreiro, Alexandre and Mohr, Henrique and Pereira Martins, Maurer and da Cruz Pacheco, Daiane and Macagnan, Ana Paula and de Cassia Santos, Aline and Bulle Oliveira, Acary Souza and Amaral de Andrade, Ana Carolina and Annes, Marcelo and Cavalcante Lino, Valeria and Pinto, Wladimir and Miranda, Carolina and Carrara, Fernanda and Souza, Iandra and Genge, Angela and Massie, Rami and Campbell, Natasha and Bril, Vera and Katzberg, Hans and Soltani, Mehran and Ng, Eduardo and Siddiqi, Zaeem and Phan, Celile and Blackmore, Derrick and Vohanka, Stanislav and ... and REGAIN Study Grp and REGAIN Study Group
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 976 - 986
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a... 
TRIAL | ENDPLATE | LOCALIZATION | COMPLEMENT INHIBITOR ECULIZUMAB | DAILY LIVING PROFILE | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | ACETYLCHOLINE-RECEPTOR | END-PLATE | CLINICAL NEUROLOGY | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Double-Blind Method | Myasthenia Gravis - blood | Outcome Assessment (Health Care) | Autoantibodies - blood | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized - administration & dosage | Myasthenia Gravis - physiopathology | Antibodies, Monoclonal, Humanized - pharmacology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Myasthenia Gravis - drug therapy | Drug Resistance | Studies | Neurology | Immunoglobulins | Activities of daily living | Myasthenia gravis | Transplants & implants | Neuromuscular junctions | Myasthenia | Patients
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