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Revista Espanola de Cardiologia, ISSN 0300-8932, 02/2019, Volume 72, Issue 2, pp. 138 - 144
Introduction and objectives: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. The current challenge relies on the accurate... 
MYBPC3 | Pathogenic variant | Truncated protein | Hypertrophic cardiomyopathy
Journal Article
REVISTA ESPANOLA DE CARDIOLOGIA, ISSN 0300-8932, 02/2019, Volume 72, Issue 2, pp. 138 - 144
Introduction and objectives: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. The current challenge relies on the accurate... 
MYBPC3 | Pathogenic variant | BINDING-PROTEIN-C | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | GUIDELINES | RISK | MYOCARDIAL CRYPTS | PREVALENCE | Truncated protein | MYBPC3 MUTATION | HCM | GENE | SEQUENCE | Hypertrophic cardiomyopathy
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2018, Volume 475, Issue 24, pp. 3933 - 3948
The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in... 
MYBPC3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | PHENOTYPES | MUTATIONS | DOMAINS | CMYBP-C
Journal Article
Revista Española de Cardiología, ISSN 0300-8932, 2016, Volume 70, Issue 2, pp. 105 - 114
Resumen Introducción y objetivos Las mutaciones en MYBPC3 son causa de miocardiopatía hipertrófica (MCH). A pesar de que la mayoría de ellas producen una... 
Cardiovascular | Miocardiopatía | Mutación en MYBPC3 | Truncated protein | Hipertrofia | Muerte súbita | Cardiomyopathy | Sudden death | MYBPC3 mutation | Proteína truncada | Hypertrophy
Journal Article
Revista Espanola de Cardiologia, ISSN 0300-8932, 02/2017, Volume 70, Issue 2, pp. 105 - 114
Introduction and objectives Mutations in MYBPC3 are the cause of hypertrophic cardiomyopathy (HCM). Although most lead to a truncating protein, the severity of... 
Truncated protein | Cardiomyopathy | Sudden death | MYBPC3 mutation | Hypertrophy
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 03/2018, Volume 122, Issue 7, pp. 918 - 920
Although I currently lead a team of cardiovascular investigators at the University of Cincinnati, my beginnings were humble, as I came from a farming family in... 
HEMATOLOGY | PERIPHERAL VASCULAR DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYBPC3 | early career | hypertrophic cardiomyopathy | myosin binding protein-C | India
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2012, Volume 52, Issue 6, pp. 1299 - 1307
Abstract Hypertrophic cardiomyopathy (HCM) is frequently caused by mutations in MYBPC3 encoding cardiac myosin-binding protein C (cMyBP-C). The mechanisms... 
Cardiovascular | Diastolic dysfunction | Ca2+ sensitivity | Ca2+ transient | Mouse model | Hypertrophy | MYOCARDIUM | BINDING-PROTEIN-C | CARDIAC & CARDIOVASCULAR SYSTEMS | FAMILIAL HYPERTROPHIC CARDIOMYOPATHY | UBIQUITIN-PROTEASOME SYSTEM | MYOCYTES | PHOSPHORYLATION | MECHANISMS | CELL BIOLOGY | GENE | MESSENGER-RNA DECAY | EXPRESSION | Cardiomyopathy, Hypertrophic - genetics | Echocardiography | Diastole | Calcium - metabolism | Cardiomyopathy, Hypertrophic - metabolism | Mice, Transgenic | Gene Knock-In Techniques | Carrier Proteins - genetics | Animals | Heart Ventricles - physiopathology | Cardiomyopathy, Hypertrophic - physiopathology | Myocytes, Cardiac - metabolism | Heterozygote | Heart Ventricles - metabolism | Mice | Myofibrils - metabolism | Mutation | Gene Order | cTnI, cardiac troponin I | Mybpc3, mouse cardiac myosin-binding protein C gene | PKA, cAMP-dependent protein kinase A | max F, maximal Ca2+-activated force | KI, homozygous Mybpc3-targeted knock-in mice | MYBPC3, human cardiac myosin-binding protein C gene | Het, heterozygous Mybpc3-targeted knock-in mice | PLB, phospholamban | KO, homozygous Mybpc3-targeted knock-out mice | Ca2+ exchanger | SERCA2, SR-Ca2+ ATPase | HCM, hypertrophic cardiomyopathy | NCX, Na+ | SL, sarcomere length | SR, sarcoplasmic reticulum | cMyBP-C, cardiac myosin-binding protein C | nH, Hill coefficient | pCa50, log of [Ca2+] required for 50% of maximal activation | LVH, left ventricular hypertrophy | CSQ, calsequestrin | Original
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 03/2019, Volume 10, p. 239
Journal Article
Revista Española de Cardiología, ISSN 0300-8932, 02/2019, Volume 72, Issue 2, pp. 138 - 144
La miocardiopatía hipertrófica (MCH) es la enfermedad cardiaca hereditaria más frecuente. El desafío actual radica en la clasificación precisa de la... 
MYBPC3 | Pathogenic variant | Truncated protein | Miocardiopatía hipertrófica | Hypertrophic cardiomyopathy | Variante patogénica | Proteína truncada
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7
Cardiomyopathy is a major cause of heart failure and sudden cardiac death; several mutations in sarcomeric protein genes have been associated with this... 
MYBPC3 | HYPERTROPHIC CARDIOMYOPATHY | PROTEIN | MULTIDISCIPLINARY SCIENCES | SOUTH-ASIA | TNNI3 | TNNT2 MUTATIONS | TAIL DOMAIN | FEATURES
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 08/2017, Volume 8, p. 558
Journal Article
Journal Article
Revista Española de Cardiología (English Edition), ISSN 1885-5857, 02/2017, Volume 70, Issue 2, pp. 105 - 114
Journal Article