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1. Full Text STING-Dependent 2′-5′ Oligoadenylate Synthetase-Like Production Is Required for Intracellular Mycobacterium leprae Survival
by De Toledo-Pinto, Thiago Gomes and Ferreira, Anna Beatriz Robottom and Ribeiro-Alves, Marcelo and Rodrigues, Luciana Silva and Batista-Silva, Leonardo Ribeiro and Silva, Bruno Jorge De Andrade and Lemes, Robertha Mariana Rodrigues and Martinez, Alejandra Nóbrega and Sandoval, Felipe Galvan and Alvarado-Arnez, Lucia Elena and Rosa, Patrícia Sammarco and Shannon, Edward Joseph and Pessolani, Maria Cristina Vidal and Pinheiro, Roberta Olmo and Antunes, Srgio Luís Gomes and Sarno, Euzenir Nunes and Lara, Flávio Alves and Williams, DIana Lynn and Ozório Moraes, Milton
The Journal of infectious diseases, ISSN 0022-1899, 07/2016, Volume 214, Issue 2, pp. 311 - 320
Leprosy | Cytoplasmic DNA sensing | Mycobacterium leprae | Autophagy | Type I IFN | OASL | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | 2',5'-Oligoadenylate Synthetase - metabolism | Leprosy - microbiology | Humans | Cells, Cultured | Leprosy - pathology | Gene Expression Profiling | Microbial Viability | Gene Knockdown Techniques | Host-Pathogen Interactions | Epithelial Cells - microbiology | Membrane Proteins - metabolism | Mycobacterium bovis - physiology | Schwann Cells - microbiology | Macrophages - microbiology | Mycobacterium leprae - physiology | Mycobacterial infections | Genetic aspects | Research | Gene expression | Ligases | Index Medicus | Abridged Index Medicus
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2. Full Text Genome-Wide Comparison of Medieval and Modern Mycobacterium leprae
by Verena J. Schuenemann and Pushpendra Singh and Thomas A. Mendum and Ben Krause-Kyora and Günter Jäger and Kirsten I. Bos and Alexander Herbig and Christos Economou and Andrej Benjak and Philippe Busso and Almut Nebel and Jesper L. Boldsen and Anna Kjellström and Huihai Wu and Graham R. Stewart and G. Michael Taylor and Peter Bauer and Oona Y.-C. Lee and Houdini H. T. Wu and David E. Minnikin and Gurdyal S. Besra and Katie Tucker and Simon Roffey and Samba O. Sow and Stewart T. Cole and Kay Nieselt and Johannes Krause
Science (American Association for the Advancement of Science), ISSN 0036-8075, 7/2013, Volume 341, Issue 6142, pp. 179 - 183
Pathogens | Mycobacterium leprae | DNA | REPORTS | Leprosy | Mycolic acids | Evolution | Genomes | Skeleton | Nucleotides | Genotypes | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Mycobacterium leprae - classification | DNA, Bacterial - isolation & purification | Leprosy - microbiology | History, Medieval | Humans | Bone and Bones - microbiology | United Kingdom | DNA, Bacterial - chemistry | Mycobacterium leprae - genetics | Phylogeny | Mycolic Acids - chemistry | Genome, Bacterial - genetics | Sweden | DNA, Bacterial - genetics | Leprosy - history | Tooth - microbiology | Denmark | Endemic Diseases - history | Leprosy - epidemiology | Mycobacterium leprae - isolation & purification | Evolution, Molecular | Genome-wide association studies | Genetic aspects | Biological markers | Observations | Genetic markers | European history | Genomics | Dispersal | Index Medicus | Drugs | Antiquities | Virulence | Deoxyribonucleic acid | Historic | Links | Sequencing | Strain
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3. Full Text Comparative genomic and phylogeographic analysis of Mycobacterium leprae
by Zidane, Nora and Macdonald, Murdo and Busso, Philippe and Stefani, Mariane M and Monot, Marc and Matsuoka, Masanori and Khamispour, Ali and Taylor, G Michael and Mays, Simon and Singh, Pushpendra and Dowlati, Yahya and Lockwood, Diana and Banu, Sayera and Sherafi, Diana and Harshman, Keith and Gattiker, Alexandre and Jianping, Shen and Watson, Claire and Rea, Thomas H and Thomas, Jérôme and Rougemont, Jacques and Cole, Stewart T and Donoghue, Helen D and Brennan, Patrick J and Honoré, Nadine and Paniz-Mondolfi, Alberto and Vera-Cabrera, Lucio and Spencer, John S and Bouwman, Abi and Garnier, Thierry and Sapkota, Bishwa Raj
Nature genetics, ISSN 1061-4036, 12/2009, Volume 41, Issue 12, pp. 1282 - 1289
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Geography | Mycobacterium leprae - classification | Genes, Bacterial | Genome, Bacterial | Leprosy - microbiology | Recombination, Genetic | Humans | Mycobacterium leprae - genetics | Polymorphism, Single Nucleotide | Phylogeny | Leprosy - genetics | Usage | Mycobacterium leprae | Leprosy | Causes of | Genetic aspects | Research | Nucleotide sequencing | Single nucleotide polymorphisms | Health aspects | Studies | Genetic testing | Genomics | Deoxyribonucleic acid--DNA | Index Medicus
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4. Full Text Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
by Benjak, Andrej and Avanzi, Charlotte and Singh, Pushpendra and Loiseau, Chloé and Girma, Selfu and Busso, Philippe and Fontes, Amanda N. Brum and Miyamoto, Yuji and Namisato, Masako and Bobosha, Kidist and Salgado, Claudio G and Da Silva, Moisés B and Bouth, Raquel C and Frade, Marco A. C and Filho, Fred Bernardes and Barreto, Josafá G and Nery, José A.C and Bührer-Sékula, Samira and Lupien, Andréanne and Al-Samie, Abdul R and Al-Qubati, Yasin and Alkubati, Abdul S and Bretzel, Gisela and Vera-Cabrera, Lucio and Sakho, Fatoumata and Johnson, Christian R and Kodio, Mamoudou and Fomba, Abdoulaye and Sow, Samba O and Gado, Moussa and Konaté, Ousmane and Stefani, Mariane M.A and Penna, Gerson O and Suffys, Philip N and Sarno, Euzenir Nunes and Moraes, Milton O and Rosa, Patricia S and Baptista, Ida M.F. DIas and Spencer, John S and Aseffa, Abraham and Matsuoka, Masanori and Kai, Masanori and Cole, Stewart T
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 352 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Microbial Sensitivity Tests | Genome, Bacterial | Anti-Infective Agents - pharmacology | Humans | Mycobacterium leprae - drug effects | DNA, Bacterial - chemistry | Mycobacterium leprae - genetics | Codon, Nonsense | Phylogeny | Drug Resistance, Bacterial - genetics | Mycobacterium leprae - isolation & purification | Nucleotide sequence | Positive selection | Leprosy | Antimicrobial agents | Genomes | Drug resistance | Antiinfectives and antibacterials | Gene sequencing | Antibiotics | Antibiotic resistance | Skin | Mutation | Antimicrobial resistance | Deoxyribonucleic acid--DNA | Index Medicus
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5. Full Text M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
by van der Wel, Nicole and Hava, David and Houben, Diane and Fluitsma, Donna and van Zon, Maaike and Pierson, Jason and Brenner, Michael and Peters, Peter J
Cell (Cambridge), ISSN 0092-8674, 2007, Volume 129, Issue 7, pp. 1287 - 1298
CELLBIO | HUMDISEASE | MICROBIO | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Immunohistochemistry | Cell Proliferation | Intracellular Membranes - physiology | Humans | Myeloid Cells - physiology | Phagosomes - physiology | Myeloid Cells - ultrastructure | Lysosomes - physiology | Cell Movement - physiology | Intracellular Membranes - ultrastructure | Mycobacterium tuberculosis - physiology | Mycobacterium - ultrastructure | Phagosomes - ultrastructure | Membrane Proteins - metabolism | Mycobacterium leprae - physiology | Biomarkers - metabolism | Mycobacterium leprae - ultrastructure | Microscopy, Electron, Transmission | Host-Parasite Interactions - physiology | Mycobacterium - physiology | Cells, Cultured | Cytosol - ultrastructure | Mycobacterium tuberculosis - ultrastructure | Mycobacterium leprae - genetics | Gene Expression Regulation, Bacterial - physiology | Mycobacterium - genetics | Cell Compartmentation - physiology | Cell Division - physiology | Lysosomes - ultrastructure | Cell Death - physiology | Cytosol - physiology | Antigen Presentation - physiology | Myeloid Cells - microbiology | Mycobacterium tuberculosis - genetics | Tuberculosis | Index Medicus
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6. Full Text Drug-resistant M leprae
by Saunderson, Paul R., MD, MRCP
Clinics in dermatology, ISSN 0738-081X, 2016, Volume 34, Issue 1, pp. 79 - 81
Dermatology | Life Sciences & Biomedicine | Science & Technology | Leprostatic Agents - therapeutic use | Drug Resistance, Bacterial | Leprosy - drug therapy | Humans | Mycobacterium leprae - drug effects | Leprostatic Agents - pharmacology | Leprosy | Drug resistance | Index Medicus
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7. Full Text Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae
by Eiglmeier, K and Honoré, N and Woods, S. A and Caudron, B and Cole, S. T
Molecular microbiology, ISSN 0950-382X, 01/1993, Volume 7, Issue 2, pp. 197 - 206
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics | Bacteriology | Chromosome Walking | Cosmids | Genome, Bacterial | DNA, Bacterial - genetics | In Situ Hybridization | Gene Library | DNA Fingerprinting | Repetitive Sequences, Nucleic Acid | Chromosome Mapping | Mycobacterium leprae - genetics | Chromosomes, Bacterial | Index Medicus
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8. Full Text A S52P mutation in the ‘α‐crystallin domain’ of Mycobacterium leprae HSP18 reduces its oligomeric size and chaperone function
by Nandi, Sandip K and Rehna, Elengikal A. A and Panda, Alok K and Shiburaj, Sugathan and Dharmalingam, Kuppamuthu and Biswas, Ashis
The FEBS journal, ISSN 1742-464X, 12/2013, Volume 280, Issue 23, pp. 5994 - 6009
Mycobacterium leprae HSP18 | small heat shock protein | molecular chaperone | point mutation | α‐crystallin domain | α-crystallin domain | Mycobacterium leprae HSP18 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Molecular Chaperones - metabolism | Mutagenesis, Site-Directed | Mycobacterium leprae | Heat-Shock Proteins - metabolism | Protein Multimerization | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Mutant Proteins - genetics | Molecular Sequence Data | Mutant Proteins - metabolism | Mutation - genetics | alpha-Crystallins - genetics | alpha-Crystallins - metabolism | Protein Folding | Sequence Homology, Amino Acid | Heat-Shock Proteins - genetics | Mutant Proteins - chemistry | Bacterial Proteins - metabolism | Heat-Shock Proteins - chemistry | Index Medicus
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9. Mycobacterium leprae: Genes, pseudogenes and genetic diversity
by Singh, Pushpendra and Cole, Stewart T
Future microbiology, ISSN 1746-0913, 01/2011, Volume 6, Issue 1, pp. 57 - 71
leprosy | molecular epidemiology | drug-resistance | Mycobacterium leprae | pseudogene | phylogeography | Life Sciences & Biomedicine | Microbiology | Science & Technology | Genetic Variation | Genes, Bacterial | Genome, Bacterial | Pseudogenes | Base Composition | Leprosy - microbiology | Humans | Mycobacterium leprae - drug effects | Mycobacterium leprae - genetics | Polymorphism, Single Nucleotide | Drug Resistance, Multiple, Bacterial - genetics | DNA Transposable Elements
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