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Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7468, pp. 512 - 516
Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defence mechanism against invading microbes, including the... 
MYCOBACTERIUM-TUBERCULOSIS | ASSOCIATIONS | MULTIDISCIPLINARY SCIENCES | P62/SQSTM1 | DISEASE | SUSCEPTIBILITY | MITOPHAGY | DEFICIENT MICE | AUTOPHAGY | BODY FORMATION | DROSOPHILA | Ubiquitin - analysis | Drosophila melanogaster - immunology | Tuberculosis - enzymology | Mycobacterium tuberculosis - immunology | Symbiosis - immunology | Ubiquitin - metabolism | Male | Tuberculosis - microbiology | Drosophila melanogaster - genetics | Autophagy - immunology | Drosophila melanogaster - metabolism | Ubiquitin-Protein Ligases - immunology | Female | Lysine - metabolism | Mycobacterium tuberculosis - metabolism | Macrophages - microbiology | Polyubiquitin - chemistry | Tuberculosis - pathology | Polyubiquitin - metabolism | Salmonella typhimurium - immunology | Mice, Inbred C57BL | Ubiquitin - chemistry | Ubiquitin-Protein Ligases - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Ubiquitin-Protein Ligases - chemistry | Mitochondrial Degradation | Tuberculosis - immunology | Immunity, Innate - immunology | Drosophila melanogaster - microbiology | Models, Immunological | Animals | Mycobacterium marinum - immunology | Bone Marrow Cells - microbiology | Ubiquitin-Protein Ligases - deficiency | Mice | Mycobacterium tuberculosis - growth & development | Mitochondria | Tuberculosis | Bacterial infections | Microbiology | Homeostasis | Bacteria | Infections | Autophagy | Index Medicus
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2009, Volume 360, Issue 23, pp. 2397 - 2405
Journal Article
Science, ISSN 0036-8075, 1/2005, Volume 307, Issue 5707, pp. 223 - 227
The incidence of tuberculosis has been increasing substantially on a worldwide basis over the past decade, but no tuberculosis-specific drugs have been... 
Antibacterials | Mycobacterium tuberculosis | Lungs | Half lives | Antituberculars | Multidrug resistant tuberculosis | Infections | Dosage | Bacterial load | Pharmacokinetics | Research Article | ANTITUBERCULOSIS AGENTS | MULTIDISCIPLINARY SCIENCES | Antitubercular Agents - chemistry | Humans | Drug Resistance, Bacterial | Molecular Sequence Data | Male | Tuberculosis - microbiology | Mycobacterium tuberculosis - drug effects | Quinolines - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Quinolines - pharmacokinetics | Tuberculosis, Multidrug-Resistant - microbiology | Enzyme Inhibitors - chemistry | Tuberculosis - drug therapy | Bacterial Proton-Translocating ATPases - antagonists & inhibitors | Drug Evaluation, Preclinical | Drug Therapy, Combination | Mycobacterium smegmatis - enzymology | Antitubercular Agents - therapeutic use | Amino Acid Sequence | Mycobacterium smegmatis - growth & development | Bacterial Proton-Translocating ATPases - chemistry | Bacterial Proton-Translocating ATPases - metabolism | Quinolines - chemistry | Antitubercular Agents - pharmacology | Enzyme Inhibitors - pharmacology | Enzyme Inhibitors - therapeutic use | Point Mutation | Animals | Antitubercular Agents - pharmacokinetics | Mycobacterium tuberculosis - enzymology | Mycobacterium smegmatis - drug effects | Diarylquinolines | Mice | Protein Subunits - antagonists & inhibitors | Protein Subunits - chemistry | Quinolines - therapeutic use | Mycobacterium tuberculosis - growth & development | Tuberculosis, Multidrug-Resistant - drug therapy | Care and treatment | Usage | Tuberculosis | Respiratory agents | Research | Adenosine triphosphatase | Clinical trials | Drug resistance | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 27, pp. 12239 - 12244
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 47, pp. 20004 - 20009
The emergence of multidrug-resistant (MDR) tuberculosis (TB) highlights the urgent need to understand the mechanisms of resistance to the drugs used to treat... 
Tuberculosis | Mycobacterium tuberculosis | Complementary DNA | Genes | Antituberculars | Aminoglycosides | Promoter regions | Multidrug resistant tuberculosis | Genetic mutation | Start codon | SURVIVAL | SMEGMATIS | PROTEIN | PRODUCER | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | AMIKACIN | PROMOTER | EXPRESSION | MOLECULAR ANALYSIS | Acetyltransferases - pharmacology | Humans | Acetyltransferases - therapeutic use | Tuberculosis, Multidrug-Resistant - genetics | Antigens, Bacterial - genetics | Mycobacterium tuberculosis - drug effects | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Mycobacterium tuberculosis - physiology | Transcription, Genetic | Tuberculosis, Multidrug-Resistant - enzymology | Antitubercular Agents - therapeutic use | Promoter Regions, Genetic | Drug Resistance, Multiple, Bacterial - physiology | Antitubercular Agents - pharmacology | Bacterial Proteins - genetics | Kanamycin - therapeutic use | Amikacin - pharmacology | Kanamycin - pharmacology | Amikacin - therapeutic use | Mycobacterium tuberculosis - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Antigens, Bacterial - metabolism | Tuberculosis, Multidrug-Resistant - drug therapy | Drug resistance in microorganisms | Pharmacogenetics | Kanamycin | Dosage and administration | Research | Properties | Drug therapy | Proteins | Medical treatment | Bacteria | Mutation | Drug resistance | Ribonucleic acid--RNA | Drugs | Amikacin | Transcription | Minimum inhibitory concentration | Clinical isolates | Lead | Acetyltransferase | Promoters | Index Medicus | Biological Sciences
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Journal Article
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