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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2013, Volume 110, Issue 24, pp. E2209 - E2218
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple... 
Carbohydrates | Animal models | Infectious diseases | Malaria | Immunotherapy | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plasmodium berghei - immunology | Gram-Positive Bacteria - physiology | Acetylglucosamine - immunology | Plasmodium berghei - physiology | Bacterial Capsules - metabolism | Humans | Antibodies, Bacterial - pharmacology | Mycoses - microbiology | Host-Pathogen Interactions - drug effects | Gram-Negative Bacteria - immunology | Host-Pathogen Interactions - immunology | Fungi - immunology | Time Factors | Bacterial Infections - immunology | Immunoglobulin G - immunology | Fungi - physiology | Immunoglobulin G - pharmacology | Gram-Positive Bacteria - immunology | Gram-Negative Bacteria - physiology | Antibodies, Monoclonal - immunology | Bacterial Infections - microbiology | Staphylococcus aureus - metabolism | Mycoses - prevention & control | Opsonin Proteins - immunology | Antibodies, Monoclonal - pharmacology | Malaria - immunology | Mice, Inbred C57BL | Protein Binding - immunology | Malaria - prevention & control | Bacterial Infections - prevention & control | Animals | Malaria - parasitology | Survival Analysis | Antibodies, Bacterial - immunology | Staphylococcus aureus - immunology | Mice | Mycoses - immunology | Bacterial Capsules - immunology | carbohydrates | Biological Sciences | animal models | PNAS Plus | immunotherapy | infectious diseases | malaria
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2014, Volume 193, Issue 6, pp. 3013 - 3022
Helicobacter pylori incites a futile inflammatory response, which is the key feature of its immunopathogenesis. This leads to the ability of this bacterial... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Helicobacter pylori - immunology | Gastric Mucosa - microbiology | Nitric Oxide Synthase Type II - biosynthesis | Humans | Antigens, Bacterial - immunology | Helicobacter pylori - pathogenicity | Th1 Cells - immunology | Antigens, Bacterial - genetics | MAP Kinase Signaling System - immunology | NF-E2-Related Factor 2 - immunology | Heme Oxygenase-1 - genetics | Signal Transduction - immunology | Gastritis - microbiology | Bacterial Proteins - immunology | Phosphorylation - immunology | Macrophages - immunology | Cell Line | Heme Oxygenase-1 - biosynthesis | Stomach - pathology | Membrane Proteins - genetics | Mice, Inbred C57BL | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Phagocytosis - immunology | Membrane Proteins - immunology | Gastric Mucosa - cytology | Helicobacter Infections - immunology | Imidazoles - pharmacology | Inflammation - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Heme Oxygenase-1 - antagonists & inhibitors | Macrophages - enzymology | Mice, Knockout | Gastric Mucosa - immunology | Membrane Proteins - biosynthesis | Animals | Membrane Proteins - antagonists & inhibitors | Gastritis - immunology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Heme Oxygenase-1 - immunology | Th17 Cells - immunology | Interleukin-10 - biosynthesis | Mice | Pyridines - pharmacology | Stomach - microbiology | Helicobacter Infections - microbiology | Life Sciences
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 312 - 322.e7
Background The mechanism underlying severe asthma with fungal sensitization (SAFS) is unknown. IL-33 is important in fungus-induced asthma exacerbations, but... 
Allergy and Immunology | steroid resistance | Severe asthma | innate immunity | IL-33 | fungal sensitization | pediatric | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Interleukin-1 Receptor-Like 1 Protein | Anti-Asthmatic Agents - therapeutic use | Humans | Receptors, Interleukin - deficiency | Interleukin-13 - immunology | Omalizumab | Male | Th2 Cells - immunology | Interleukins - genetics | Interleukin-13 - genetics | Immunoglobulin E - immunology | Immunoglobulin E - genetics | Interleukins - immunology | Asthma - immunology | Female | Antibodies, Anti-Idiotypic - therapeutic use | Child | Th2 Cells - pathology | Disease Models, Animal | Animals, Newborn | Severity of Illness Index | Pyroglyphidae - chemistry | Antibodies, Monoclonal, Humanized - therapeutic use | Skin Tests | Receptors, Interleukin - immunology | Interleukin-33 | Asthma - drug therapy | Receptors, Interleukin - genetics | Alternaria - immunology | Cladosporium - immunology | Animals | Asthma - complications | Aspergillus fumigatus - immunology | Budesonide - therapeutic use | Mycoses - pathology | Adolescent | Mycoses - drug therapy | Mice | Mycoses - complications | Asthma - pathology | Mycoses - immunology | Pyroglyphidae - immunology | Pediatrics | Asthma in children | Fungi | Cytokines | Mortality | Smooth muscle | Inflammation | Allergies | Morbidity | Asthma | Milk | ABPA, Allergic bronchopulmonary aspergillosis | ICOS, Inducible costimulator | SPT, Skin prick test | sIgE, Specific IgE | BAL, Bronchoalveolar lavage | HDM, House dust mite | SAFS, Severe asthma with fungal sensitization | MMP-9, Matrix metalloproteinase 9 | Asthma and Lower Airway Disease | STRA, Severe therapy-resistant asthma | ILC, Innate lymphoid cell | AHR, Airway hyperresponsiveness
Journal Article
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 10/2011, Volume 166, Issue 1, pp. 1 - 15
Summary While interleukin (IL)‐1β plays an important role in combating the invading pathogen as part of the innate immune response, its dysregulation is... 
infections | NLRP3 | interleukin‐1 | innate immunity | inflammasome | Innate immunity | Interleukin-1 | Infections | Inflammasome | Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Enzyme Precursors - genetics | Gout - drug therapy | Mycoses - microbiology | Caspase 1 - metabolism | Virus Diseases - virology | Caspase 1 - immunology | Interleukin-1beta - genetics | Signal Transduction - immunology | Bacterial Infections - immunology | Inflammation - drug therapy | Interleukin-1beta - metabolism | Diabetes Mellitus, Type 2 - immunology | Gout - immunology | Hereditary Autoinflammatory Diseases - pathology | Bacterial Infections - microbiology | Carrier Proteins - immunology | Molecular Targeted Therapy - methods | Virus Diseases - immunology | Anti-Inflammatory Agents - pharmacology | Enzyme Precursors - immunology | Gene Expression Regulation | Hereditary Autoinflammatory Diseases - immunology | Interleukin-1beta - immunology | Mice, Transgenic | Inflammation - immunology | Immunity, Innate | Hereditary Autoinflammatory Diseases - drug therapy | Inflammasomes - genetics | Neoplasms - drug therapy | Carrier Proteins - genetics | Enzyme Precursors - metabolism | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | Gout - pathology | Neoplasms - immunology | Inflammasomes - immunology | Mice | Diabetes Mellitus, Type 2 - pathology | Enzyme Activation | Diabetes Mellitus, Type 2 - drug therapy | Neoplasms - pathology | Mycoses - immunology | Medical research | Immune system | Infection | Pathogens | Immune response | Diabetes mellitus | Gout | Interleukin 1 | Cancer | Caspase-1 | interleukin-1 | Review
Journal Article