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1. Full Text Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump
by Burger, Herman and Tol, H and Boersma, Anton and Brok, Mariël and Wiemer, Erik and Stoter, Gerrit and Nooter, Kees
Blood, ISSN 0006-4971, 01/2004, Volume 104, Issue 9, pp. 2940 - 2942
Binding, Competitive | Breast Neoplasms/drug therapy/pathology | Humans | Mycotoxins/analogs & derivatives/pharmacology | Substrate Specificity | Drug Resistance, Neoplasm | ATP-Binding Cassette Transporters/metabolism | Mitoxantrone/metabolism | Pyrimidines/metabolism | Doxorubicin/metabolism | Piperazines/metabolism | Cell Line, Tumor | Neoplasm Proteins/metabolism | Carbon Radioisotopes | Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Chemotherapy | Pharmacology. Drug treatments | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Antineoplastic agents | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Mitoxantrone - metabolism | Piperazines - metabolism | Neoplasm Proteins - metabolism | Breast Neoplasms - drug therapy | Imatinib Mesylate | Pyrimidines - metabolism | Breast Neoplasms - pathology | ATP-Binding Cassette Transporters - metabolism | Doxorubicin - metabolism | Benzamides | Mycotoxins - analogs & derivatives | Mycotoxins - pharmacology | Index Medicus | Abridged Index Medicus
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2. Full Text The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
by Kasper, L and Konig, A and Koenig, P.A and Gresnigt, M.S and Westman, J and mmond, R.A and Lionakis, M.S and Gross, O and Ruland, J and Naglik, J.R and Hube, B
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 4260 - 20
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Inflammation - pathology | Leukocytes, Mononuclear - metabolism | Inflammasomes - metabolism | Humans | Actins - metabolism | Fungal Proteins - toxicity | Caspase 1 - metabolism | Necrosis | Interleukin-1beta - metabolism | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Female | Phagocytes - cytology | Cell Death - drug effects | Dendritic Cells - metabolism | Phagosomes - drug effects | Leukocytes, Mononuclear - drug effects | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Phagocytes - drug effects | Mice, Inbred C57BL | Phagosomes - metabolism | Phagocytes - metabolism | Mycotoxins - toxicity | Potassium - pharmacology | Macrophages - metabolism | Animals | Leukocytes, Mononuclear - cytology | Macrophages - drug effects | Bone Marrow Cells - metabolism | Efflux | Pathogens | Cytolysis | Dendritic cells | Immune clearance | Opportunist infection | Leukocytes (mononuclear) | Glucose | Macrophages | Caspase-1 | Fungi | Phagocytes | Cell activation | Cell death | Hyphae | Lysis | Potassium | Immune system | Apoptosis | Index Medicus
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3. Full Text Metabolism of the Fusarium Mycotoxins T‑2 Toxin and HT‑2 Toxin in Wheat
by Nathanail, Alexis V and Varga, Elisabeth and Meng-Reiterer, Jacqueline and Bueschl, Christoph and Michlmayr, Herbert and Malachova, Alexandra and Fruhmann, Philipp and Jestoi, Marika and Peltonen, Kimmo and Adam, Gerhard and Lemmens, Marc and Schuhmacher, Rainer and Berthiller, Franz
Journal of agricultural and food chemistry, ISSN 0021-8561, 09/2015, Volume 63, Issue 35, pp. 7862 - 7872
liquid chromatography-high resolution mass spectrometry | stable isotopes | cereals | masked mycotoxins | trichothecenes | metabolomics | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | T-2 Toxin - metabolism | Metabolomics | Mycotoxins - analysis | Fusarium - chemistry | Food Contamination - analysis | Chromatography, High Pressure Liquid | T-2 Toxin - analogs & derivatives | Tandem Mass Spectrometry | Isotope Labeling | Mycotoxins - metabolism | T-2 Toxin - analysis | Triticum - chemistry | Triticum - microbiology | Fusarium - metabolism | Index Medicus | liquid chromatography−high resolution mass spectrometry
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4. Full Text Secondary metabolism: regulation and role in fungal biology
by Fox, Ellen M and Howlett, Barbara J
Current opinion in microbiology, ISSN 1369-5274, 2008, Volume 11, Issue 6, pp. 481 - 487
Pathology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Mycotoxins - biosynthesis | Anti-Bacterial Agents - biosynthesis | Biosynthetic Pathways - genetics | Fungi - metabolism | Antibiosis | Fungi - genetics | Physiological aspects | Laws, regulations and rules | Genomics | Plant metabolites | Index Medicus
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5. Full Text Candidalysin is a fungal peptide toxin critical for mucosal infection
by Moyes, David L and Wilson, Duncan and Richardson, Jonathan P and Mogavero, Selene and Tang, Shirley X and Wernecke, Julia and Höfs, Sarah and Gratacap, Remi L and Robbins, Jon and Runglall, Manohursingh and Murciano, Celia and Blagojevic, Mariana and Thavaraj, Selvam and Förster, Toni M and Hebecker, Betty and Kasper, Lydia and Vizcay, Gema and Iancu, Simona I and Kichik, Nessim and Häder, Antje and Kurzai, Oliver and Luo, Ting and Krüger, Thomas and Kniemeyer, Olaf and Cota, Ernesto and Bader, Oliver and Wheeler, Robert T and Gutsmann, Thomas and Hube, Bernhard and Naglik, Julian R
Nature (London), ISSN 0028-0836, 04/2016, Volume 532, Issue 7597, pp. 64 - 68
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Virulence - drug effects | Virulence Factors - genetics | Calcium - metabolism | Epithelial Cells - drug effects | Humans | Fungal Proteins - toxicity | Candida albicans - metabolism | Candidiasis - microbiology | Cytotoxins - toxicity | Host-Pathogen Interactions - immunology | Cytotoxins - metabolism | Mycotoxins - metabolism | Mycotoxins - genetics | Candidiasis - pathology | Virulence Factors - toxicity | Candida albicans - pathogenicity | Epithelial Cells - pathology | Fungal Proteins - genetics | Candida albicans - immunology | Mycotoxins - toxicity | Candidiasis - metabolism | Mucous Membrane - pathology | Signal Transduction - drug effects | Cell Membrane Permeability - drug effects | Epithelial Cells - immunology | Virulence Factors - metabolism | Cytotoxins - genetics | Mucous Membrane - microbiology | Fungal Proteins - metabolism | Candida albicans | Fungi | Physiological aspects | Mucous membrane | Proteins | Yeast | Peptides | Cytokines | Pathogenesis | Toxins | Fungal infections | Index Medicus
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6. Full Text Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in pigs
by Nagl, Veronika and Woechtl, Bettina and Schwartz-Zimmermann, Heidi Elisabeth and Hennig-Pauka, Isabel and Moll, Wulf-Dieter and Adam, Gerhard and Berthiller, Franz
Toxicology letters, ISSN 0378-4274, 08/2014, Volume 229, Issue 1, pp. 190 - 197
Conjugated mycotoxins | ADME | Swine | Gut | Life Sciences & Biomedicine | Toxicology | Science & Technology | Reproducibility of Results | Glucosides - urine | Injections, Intravenous | Administration, Oral | Biological Availability | Male | Trichothecenes - pharmacokinetics | Glucosides - pharmacokinetics | Chromatography, High Pressure Liquid | Weight Loss - drug effects | Glucosides - metabolism | Intestinal Absorption | Vomiting - chemically induced | Animals | Feces - chemistry | Trichothecenes - metabolism | Biotransformation | Mass Spectrometry | Anorexia - chemically induced | Indicators and Reagents | Mycotoxins - metabolism | Trichothecenes - urine | Physiological aspects | Cells | Index Medicus | Urine | Pigs | Metabolites | Mycotoxins | Biocompatibility | Digestion | Feces | Metabolism
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7. Full Text Protein kinase FgSch9 serves as a mediator of the target of rapamycin and high osmolarity glycerol pathways and regulates multiple stress responses and secondary metabolism in Fusarium graminearum
by Gu, Qin and Zhang, Chengqi and Yu, Fangwei and Yin, Yanni and Shim, Won‐Bo and Ma, Zhonghua
Environmental microbiology, ISSN 1462-2912, 08/2015, Volume 17, Issue 8, pp. 2661 - 2676
Life Sciences & Biomedicine | Microbiology | Science & Technology | Protein Kinases - metabolism | Osmotic Pressure | Oxidative Stress | TOR Serine-Threonine Kinases - metabolism | Virulence | Fusarium - enzymology | Secondary Metabolism | Mycotoxins - biosynthesis | Transcription Factors - metabolism | Osmolar Concentration | Glycerol - metabolism | Hyphae - metabolism | Spores, Fungal - metabolism | Cell Wall - metabolism | Fusarium - genetics | Fusarium - pathogenicity | Fungal Proteins - metabolism | Glycerin | Genetic research | Physiological aspects | Glycerol | Protein kinases | Analysis | Mutation | Kinases | Metabolism | Index Medicus
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8. Full Text Zearalenone-16‑O‑glucoside: A New Masked Mycotoxin
by Kovalsky Paris, Maria Paula and Schweiger, Wolfgang and Hametner, Christian and Stückler, Romana and Muehlbauer, Gary J and Varga, Elisabeth and Krska, Rudolf and Berthiller, Franz and Adam, Gerhard
Journal of agricultural and food chemistry, ISSN 0021-8561, 02/2014, Volume 62, Issue 5, pp. 1181 - 1189
xenoestrogen | zearalenone | Fusarium | barley | Brachypodium | heterologous expression | wheat | UDP-glucosyltransferase | yeast | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Brachypodium - metabolism | Food Contamination | Humans | Male | Intestines - metabolism | Hordeum - chemistry | Triticum - metabolism | Glucosyltransferases - metabolism | Hordeum - enzymology | Microbiota | Glucosides - chemistry | Adult | Female | Mycotoxins - metabolism | Plant Proteins - metabolism | Brachypodium - chemistry | Glucosyltransferases - genetics | Bacteria - metabolism | Mycotoxins - chemistry | Hordeum - metabolism | Zearalenone - chemistry | Glucosides - metabolism | Plant Proteins - genetics | Intestines - microbiology | Zearalenone - metabolism | Triticum - chemistry | Hordeum - genetics | Index Medicus
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9. Full Text Cellular compartmentalization of secondary metabolism
by Kistler, H. Corby and Broz, Karen
Frontiers in microbiology, ISSN 1664-302X, 2015, Volume 6, pp. 68 - 68
Polyketide | Terpene | Mycotoxin | Penicillin | Deoxynivalenol | Non-ribosomal peptide | Aflatoxin | Life Sciences & Biomedicine | Microbiology | Science & Technology | mycotoxin | terpenoid | aflatoxin | Penicillin G | polyketide
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