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The Journal of immunology (1950), ISSN 1550-6606, 11/2009, Volume 183, Issue 10, pp. 6681 - 6688
The alpha 7 nicotinic acetylcholine receptor (nAChR) was recently described as an anti-inflammatory target in both macrophages and T cells. Its expression by... 
Life Sciences & Biomedicine | Immunology | Science & Technology | GATA3 Transcription Factor - agonists | T-Box Domain Proteins - antagonists & inhibitors | Encephalomyelitis, Autoimmune, Experimental - immunology | NF-kappa B - metabolism | Interferon-gamma - metabolism | Interleukin-4 - agonists | RNA, Messenger - metabolism | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | GATA3 Transcription Factor - metabolism | Th1 Cells - drug effects | Antigen-Presenting Cells - metabolism | NF-kappa B - antagonists & inhibitors | Antigen-Presenting Cells - drug effects | Myelin-Oligodendrocyte Glycoprotein | T-Box Domain Proteins - metabolism | Interleukins - antagonists & inhibitors | Mice, Knockout | Spinal Cord - immunology | Interleukin-4 - immunology | Receptors, Nicotinic - immunology | Glycoproteins - immunology | Mice | alpha7 Nicotinic Acetylcholine Receptor | Tumor Necrosis Factor-alpha - metabolism | RNA, Messenger - immunology | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - metabolism | GATA3 Transcription Factor - immunology | Interleukin-17 - immunology | NF-kappa B - immunology | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Nicotine - pharmacology | Spinal Cord - pathology | Interleukins - immunology | Interferon-gamma - antagonists & inhibitors | Female | RNA, Messenger - drug effects | Receptors, Nicotinic - drug effects | Interleukin-4 - metabolism | Mice, Inbred C57BL | Antigen-Presenting Cells - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Interferon-gamma - immunology | Cell Proliferation - drug effects | Receptors, Nicotinic - genetics | CD4-Positive T-Lymphocytes - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Journal of the peripheral nervous system, ISSN 1085-9489, 03/2012, Volume 17, Issue 1, pp. 62 - 71
Neurofascin‐186 (NF186), neuronal cell adhesion molecule (NrCAM), and gliomedin are adhesion molecules playing a central role in the formation of nodes of... 
myelin | Guillain‐Barré syndrome | molecular immunogene | ganglioside | peripheral neuropathology | Ganglioside | Myelin | Peripheral neuropathology | Molecular immunogene | Guillain-Barré syndrome | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Contactins - immunology | Neural Cell Adhesion Molecules - immunology | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - blood | Ranvier's Nodes - immunology | Autoantibodies - blood | Humans | Middle Aged | Child, Preschool | Infant | Male | Cell Adhesion Molecules - immunology | Young Adult | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - immunology | Immunoglobulin G - immunology | Guillain-Barre Syndrome - blood | Adult | Female | Child | Nerve Growth Factors - immunology | Nerve Tissue Proteins | Membrane Proteins | Autoantibodies - immunology | Guillain-Barre Syndrome - immunology | Autoantigens - immunology | Adolescent | Aged | Viral antibodies | Autoimmunity | Antigens | Immunoglobulins | Autoantibodies | Adsorption | Guillain-Barre syndrome | Analysis | Immunoglobulin G | Antibodies | Antigenic determinants | Immunoglobulin M | Animal models | Inflammation | Epitopes | Polyneuropathy | Disease control | Cell adhesion molecules | Demyelination | Etiology | contactin | Nodes of Ranvier | NODAL protein | Index Medicus | Life Sciences | Biomolecules | Biochemistry, Molecular Biology
Journal Article
Journal Article
The Journal of immunology (1950), ISSN 0022-1767, 01/2007, Volume 178, Issue 2, pp. 1068 - 1076
Journal Article
Immunology letters, ISSN 0165-2478, 2017, Volume 183, pp. 79 - 85
.... • Molecular mimicry between myelin proteins and endogenous retroviral proteins proposed as a basis... 
Allergy and Immunology | Autoimmunity | Human endogenous retroviruses | Multiple sclerosis | Molecular mimicry | HLA DR2 haplotype | Myelin proteins | Life Sciences & Biomedicine | Immunology | Science & Technology | Myelin-Oligodendrocyte Glycoprotein - immunology | Pregnancy Proteins - chemistry | Gene Products, env - immunology | Humans | Male | Pregnancy Proteins - metabolism | Endogenous Retroviruses - chemistry | Gene Products, env - metabolism | Molecular Mimicry | Endogenous Retroviruses - metabolism | T-Lymphocytes - metabolism | Myelin Basic Protein - chemistry | Peptide Fragments - immunology | Viral Envelope Proteins - metabolism | Myelin Proteins - immunology | Female | Multiple Sclerosis - metabolism | Amino Acid Sequence | Computational Biology - methods | Peptide Fragments - metabolism | Myelin Basic Protein - metabolism | HLA-DR2 Antigen - metabolism | Pregnancy Proteins - immunology | Myelin Basic Protein - immunology | HLA-DR2 Antigen - immunology | Sequence Homology, Amino Acid | Myelin Proteins - chemistry | Myelin-Oligodendrocyte Glycoprotein - chemistry | Peptide Fragments - chemistry | Myelin-Oligodendrocyte Glycoprotein - metabolism | Gene Products, env - chemistry | Viral Envelope Proteins - chemistry | Multiple Sclerosis - pathology | Protein Binding | T-Lymphocytes - immunology | Multiple Sclerosis - etiology | Myelin Proteins - metabolism | Antigenic determinants | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 09/2015, Volume 6, Issue 1, pp. 8164 - 8164
.... Here we show that fibrinogen, a central blood coagulation protein deposited in the CNS after blood-brain barrier disruption, induces encephalitogenic adaptive immune responses and peripheral... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Myelin-Oligodendrocyte Glycoprotein - immunology | Cell Proliferation | Chemokine CCL2 - immunology | Demyelinating Diseases - genetics | Encephalomyelitis, Autoimmune, Experimental - immunology | Gene Expression Profiling | Brain - metabolism | Autoimmunity - immunology | Demyelinating Diseases - immunology | Fibrinogen - pharmacology | Receptors, Antigen, T-Cell - immunology | Fibrinogen - immunology | Receptors, Chemokine - genetics | DNA-Binding Proteins - immunology | Rats | Antigen Presentation - genetics | Antigen Presentation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microglia | Brain - drug effects | Genes, MHC Class II - genetics | Spinal Cord - immunology | Fibrin | Adaptive Immunity - drug effects | Brain - pathology | Mice | CX3C Chemokine Receptor 1 | Blood-Brain Barrier | Spinal Cord - drug effects | Spinal Cord - metabolism | Autoimmunity - genetics | Genes, MHC Class II - immunology | Homeodomain Proteins - immunology | Th1 Cells - immunology | Adaptive Immunity - genetics | CD11b Antigen - genetics | Flow Cytometry | Spinal Cord - pathology | Chemokine CXCL10 - immunology | Adaptive Immunity - immunology | Macrophages - immunology | CD11b Antigen - immunology | Receptors, Chemokine - immunology | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | Chemokine CXCL10 - genetics | Antigen Presentation - drug effects | Brain - immunology | Autoimmunity - drug effects | Chemokines | Index Medicus
Journal Article
Brain (London, England : 1878), ISSN 0006-8950, 09/2004, Volume 127, Issue 9, pp. 1928 - 1941
The reasons for the eventual failure of repair mechanisms in multiple sclerosis are unknown. The presence of precursor and immature oligodendrocytes in some... 
Multiple sclerosis | Jagged | Oligodendrocyte | Remyelination | Notch | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Oligodendroglia - metabolism | RNA, Messenger - immunology | Stem Cells - immunology | Gene Expression - genetics | Receptors, Cell Surface - analysis | Lac Operon - genetics | RNA, Messenger - metabolism | Stem Cells - metabolism | Schwann Cells - immunology | Membrane Proteins - analysis | Aging - immunology | Cerebellum - immunology | Oligodendroglia - immunology | Astrocytes - immunology | Serrate-Jagged Proteins | Female | Membrane Proteins - metabolism | Rhombencephalon - immunology | Transcription Factors - immunology | Macrophages - immunology | Jagged-1 Protein | Multiple Sclerosis - metabolism | Myelin Sheath - physiology | Calcium-Binding Proteins | Intercellular Signaling Peptides and Proteins | Intracellular Signaling Peptides and Proteins | Rats | Receptors, Cell Surface - metabolism | Membrane Proteins - immunology | Mice, Transgenic | Rats, Sprague-Dawley | Receptors, Cell Surface - immunology | Mice, Knockout | Trigeminal Ganglion - immunology | Transcription Factors - metabolism | Animals | Multiple Sclerosis - immunology | Mice | Transcription Factors - analysis | Receptor, Notch1 | Axons - immunology | Brain - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 39, pp. 28301 - 28308
...€ The M-protein is expressed on the cell membrane and secreted into the blood. We previously showed that ligand-toxin conjugates (LTC... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Recombinant Fusion Proteins - immunology | Hemolysin Proteins - immunology | Hemolysin Proteins - genetics | Bacterial Proteins - chemistry | Peptides - genetics | Multiple Myeloma - immunology | Antineoplastic Agents - therapeutic use | Myelin Basic Protein - genetics | Myelin Basic Protein - chemistry | Bacterial Toxins - genetics | Antibodies, Monoclonal - immunology | Gene Expression | Ricin - therapeutic use | Antineoplastic Agents - immunology | Bacterial Toxins - immunology | Peptides - immunology | Recombinant Fusion Proteins - chemistry | Hemolysin Proteins - therapeutic use | Bacterial Toxins - chemistry | Bacterial Toxins - therapeutic use | Myelin Basic Protein - immunology | Immunotoxins - therapeutic use | Models, Biological | Hybridomas | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Ligands | Ricin - genetics | Mice | Bacillus thuringiensis - chemistry | Recombinant Fusion Proteins - therapeutic use | Hemolysin Proteins - chemistry | Myeloma Proteins - genetics | Bacterial Proteins - therapeutic use | Multiple Myeloma - drug therapy | Ricin - chemistry | Bacillus thuringiensis - genetics | Endotoxins - chemistry | Bacterial Proteins - immunology | Myeloma Proteins - immunology | Bacillus thuringiensis - immunology | Immunotoxins - immunology | Peptides - chemistry | Endotoxins - genetics | Bacterial Proteins - genetics | Drug Resistance, Neoplasm - immunology | Antineoplastic Agents - chemistry | Ricin - immunology | Endotoxins - therapeutic use | Immunotoxins - genetics | Animals | Endotoxins - immunology | Myeloma Proteins - antagonists & inhibitors | Myelin Basic Protein - therapeutic use | Peptides - therapeutic use | Index Medicus
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 05/2013, Volume 190, Issue 9, pp. 4595 - 4607
...), reduces disease severity. This suggested that activators of SIRT1, a highly conserved NAD-dependent protein deacetylase, might have immune-modulating or neuroprotective therapeutic effects in EAE... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Myelin-Oligodendrocyte Glycoprotein - immunology | Spinal Cord - drug effects | Spinal Cord - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Apoptosis - drug effects | NAD - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Brain-Derived Neurotrophic Factor - immunology | Stilbenes - pharmacology | Demyelinating Diseases - metabolism | Inflammation - metabolism | Neuroprotective Agents - pharmacology | Inflammation - drug therapy | Demyelinating Diseases - immunology | Female | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Neurons - drug effects | NAD - metabolism | Demyelinating Diseases - drug therapy | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Neurons - immunology | Sirtuin 1 - biosynthesis | Axons - drug effects | Axons - metabolism | Inflammation - immunology | Spinal Cord - immunology | Animals | Apoptosis - immunology | Sirtuin 1 - immunology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Axons - immunology | Index Medicus | Abridged Index Medicus | Neuroprotection | Sirtuin1 (SIRT1) | Inflammation | Multiple sclerosis (MS) | Demyelination | Experimental Autoimmune Encephalomyelitis (EAE)
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 10/2018, Volume 115, Issue 42, pp. E9849 - E9858
Journal Article