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Multiple sclerosis, ISSN 1352-4585, 1995
Journal
The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 8077 - 8087
Sulfatide, a major lipid component of myelin sheath, participates in diverse cellular events of the CNS, and its cellular level has recently been implicated in... 
L-SELECTIN | AUTOIMMUNITY | ALZHEIMERS-DISEASE | IN-VIVO | METACHROMATIC LEUKODYSTROPHY | CENTRAL-NERVOUS-SYSTEM | MICROGLIAL CELLS | IMMUNOLOGY | CEREBROSPINAL-FLUID | EXPRESSION | T-CELLS | Inflammation - chemically induced | Brain Diseases - metabolism | Inflammation - pathology | Microglia - metabolism | Antigens, CD1d - immunology | NF-kappa B - immunology | Transcription Factor AP-1 - immunology | MAP Kinase Kinase 4 - immunology | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Transcription Factor AP-1 - metabolism | Enzyme Activation - immunology | Extracellular Signal-Regulated MAP Kinases - immunology | Brain Diseases - chemically induced | L-Selectin - metabolism | Brain Diseases - immunology | L-Selectin - immunology | MAP Kinase Kinase 4 - metabolism | Microglia - immunology | Time Factors | Natural Killer T-Cells - metabolism | Inflammation Mediators - metabolism | Natural Killer T-Cells - pathology | Antigens, CD1d - genetics | Microglia - pathology | Sulfoglycosphingolipids - toxicity | p38 Mitogen-Activated Protein Kinases - metabolism | Sulfoglycosphingolipids - chemistry | Inflammation Mediators - immunology | Myelin Sheath - immunology | Sulfoglycosphingolipids - immunology | p38 Mitogen-Activated Protein Kinases - genetics | Inflammation - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Antigens, CD1d - metabolism | Animals | Brain Diseases - pathology | Down-Regulation - immunology | Inflammation - genetics | Mice | Myelin Sheath - chemistry | Enzyme Activation - genetics | Natural Killer T-Cells - immunology
Journal Article
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7374, pp. 538 - 541
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2008, Volume 205, Issue 7, pp. 1535 - 1541
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2008, Volume 205, Issue 7, pp. 1517 - 1522
Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR-BETA | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TH2 CELLS | MULTIPLE-SCLEROSIS | IFN-GAMMA | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | DIFFERENTIATION | INDUCTION | IMMUNOLOGY | T-H-17 CELLS | T-BET | Dendritic Cells - immunology | Humans | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Interleukin-23 - genetics | Encephalomyelitis, Autoimmune, Experimental - genetics | Disease Susceptibility | Macrophages - pathology | Interleukin-17 - genetics | Interleukin-12 Subunit p35 - genetics | Interleukin-23 - immunology | Mice, Knockout | Models, Immunological | Up-Regulation - immunology | Uveitis - immunology | Mice | Uveitis - genetics | Proteins - antagonists & inhibitors | Eye - pathology | Chemokines, CXC - immunology | Interleukin-17 - immunology | Autoimmunity - genetics | Neutralization Tests | Adoptive Transfer | Paralysis - pathology | Th1 Cells - immunology | Central Nervous System - immunology | Eye - immunology | Nitric Oxide Synthase Type II - immunology | Female | Interferon-gamma - genetics | Macrophages - immunology | Neutrophils - pathology | Inflammation Mediators - immunology | Cell Line | Encephalomyelitis, Autoimmune, Experimental - pathology | Myelin Sheath - immunology | Myelin Sheath - pathology | Gene Expression Regulation - immunology | Uveitis - prevention & control | Mice, Inbred C57BL | Neutrophils - immunology | Paralysis - immunology | Up-Regulation - genetics | Proteins - immunology | Antibodies - pharmacology | Gene Expression Regulation - drug effects | Animals | Interleukin-12 Subunit p35 - immunology | Interleukin-17 - antagonists & inhibitors | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Antigens - immunology | Autoimmunity - drug effects | Uveitis - pathology | Commentaries
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 06/2017, Volume 88, Issue 6, pp. 465 - 473
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e54722
Background: Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory... 
IN-VITRO | MULTIPLE-SCLEROSIS | MICROGLIA | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | DEVELOPING OLIGODENDROCYTES | LIPOPOLYSACCHARIDE | INJURY | REMYELINATION | CENTRAL-NERVOUS-SYSTEM | DEGENERATION | Free Radical Scavengers - pharmacology | Neuritis - metabolism | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Pyruvates - pharmacology | Oxidative Stress | Myelin Sheath - drug effects | Demyelinating Diseases - metabolism | Cerebellum - immunology | Microglia - immunology | Oligodendroglia - physiology | Interleukin-1beta - metabolism | Demyelinating Diseases - immunology | Inflammation Mediators - metabolism | Interleukin-6 - metabolism | Interleukin-1beta - secretion | Cytokines - metabolism | Microglia - drug effects | Myelin Sheath - immunology | Myelin Sheath - pathology | Tissue Culture Techniques | Cerebellum - metabolism | Mice, Inbred C57BL | Tumor Necrosis Factor-alpha - secretion | Interleukin-6 - secretion | Cerebellum - pathology | Animals | Neuritis - immunology | Interferon-beta - pharmacology | Axons - pathology | Lipopolysaccharides - pharmacology | Allopurinol - pharmacology | Mice | Axons - immunology | Nitric Oxide Synthase Type II - metabolism | Oxidases | Oxidative stress | Nervous system diseases | Multiple sclerosis | Hostages | Inflammation | Biological response modifiers | Molybdenum compounds | Tumor necrosis factor | Nitric oxide | Models | Interferon | Mitogens | Tumor necrosis factor receptors | Cerebellum | Neuroprotection | Reactive oxygen species | Biomedical research | Pathogenesis | β-Interferon | Pyruvic acid | Nervous system | Activation | Damage prevention | Blockage | Lipopolysaccharides | Interleukin 6 | Antioxidants | Mitochondria | Demyelination | Neurodegeneration | Rodents | Neurofilaments | Degeneration | Damage accumulation | Brain diseases | Free radicals | Cytokines | Neurodegenerative diseases | Myelin | Medical treatment | Allopurinol | Cultures | Tumor necrosis factor-α | Xanthine | Spheroids | Nitric-oxide synthase | Microglia | Neurological diseases | Brain research | Inhibitors | Microscopy | Xanthine oxidase | Apoptosis
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 12/2015, Volume 130, Issue 6, pp. 765 - 781
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155897
Over half of adults are seropositive for JC polyomavirus (JCV), but rare individuals develop progressive multifocal leukoencephalopathy (PML), a demyelinating... 
PATHOGENESIS | PYRAMIDAL NEURONS | VIRUS-DNA | EFALIZUMAB | REPLICATION | SEQUENCES | NONCODING CONTROL REGION | MULTIDISCIPLINARY SCIENCES | REARRANGEMENT PATTERNS | GENE-EXPRESSION | PSORIASIS PATIENTS | Myelin Sheath - pathology | Viral Fusion Proteins - genetics | JC Virus - genetics | Humans | Viral Regulatory and Accessory Proteins - genetics | Brain - virology | Leukoencephalopathy, Progressive Multifocal - virology | Male | JC Virus - physiology | Macaca mulatta | Myelin Sheath - metabolism | Brain - metabolism | Animals | Virulence - genetics | Virus Replication | Myelin Sheath - virology | Brain - pathology | JC Virus - pathogenicity | Female | Aged | Mutation | Immunocompromised host | Health aspects | Immunity | Analysis | Risk factors | Leukoencephalopathy, Progressive multifocal | Brain | VP1 protein | Multiple sclerosis | Biomedical research | Capsid protein | Destruction | Laboratories | Neuropathology | Pathogenesis | Central nervous system | Spatial discrimination | Viruses | Nervous system | Infections | Regulatory sequences | Leukoencephalopathy | Progressive multifocal leukoencephalopathy | Histopathology | Immunology | Acquired immune deficiency syndrome--AIDS | Demyelination | Autopsy | Coding | Life cycle engineering | Lesions | Localization | Deoxyribonucleic acid--DNA | CD11 antigen | Immune system | Autopsies | Psoriasis | Myelin | Neurons | Immunomodulation | Spatial analysis | Gene expression | Substantia alba | Patients | Neurology | Pathology | Brain research | Correlation analysis | Monoclonal antibodies | Adults | Life cycles | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | DNA
Journal Article