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The Journal of experimental medicine, ISSN 1540-9538, 2015, Volume 212, Issue 11, pp. 1811 - 1818
Journal Article
Cancer cell, ISSN 1535-6108, 2010, Volume 17, Issue 6, pp. 584 - 596
...). The MPN is serially transplantable and we demonstrate that the hematopoietic stem cell (HSC) compartment has the unique capacity for disease initiation but does not have a significant selective competitive advantage over wild-type HSCs... 
CELLCYCLE | MYELOFIBROSIS | MURINE MODEL | POLYCYTHEMIA-VERA | ACTIVATING MUTATION | ONCOLOGY | TYROSINE KINASE JAK2 | CONDITIONAL EXPRESSION | MYELOID-LEUKEMIA | DISORDERS | QUIESCENT | ESSENTIAL THROMBOCYTHEMIA | CELL BIOLOGY | Erythropoietin - pharmacology | Gene Expression - genetics | Cell Count | Humans | Hematocrit | Hematopoietic Stem Cells - pathology | Polycythemia Vera - genetics | Gene Expression Profiling | Myeloproliferative Disorders - pathology | Spleen - drug effects | Antigens, CD - metabolism | Bone Marrow Transplantation | Megakaryocyte-Erythroid Progenitor Cells - transplantation | Polycythemia Vera - pathology | Janus Kinase 2 - antagonists & inhibitors | Disease Models, Animal | Megakaryocyte-Erythroid Progenitor Cells - metabolism | Hematopoietic Stem Cell Transplantation | Mice, Transgenic | Myeloid Progenitor Cells - pathology | Megakaryocyte-Erythroid Progenitor Cells - drug effects | Sulfonamides - pharmacology | Megakaryocyte Progenitor Cells - metabolism | Erythroid Precursor Cells - pathology | Survival Analysis | Erythroid Precursor Cells - metabolism | Mice | Megakaryocyte Progenitor Cells - pathology | Myeloproliferative Disorders - genetics | Pyrrolidines - pharmacology | Pyrrolidines - therapeutic use | Cell Differentiation - genetics | Janus Kinase 2 - metabolism | Bone Marrow Cells - drug effects | Spleen - pathology | Hematopoietic Stem Cells - drug effects | Myeloid Progenitor Cells - metabolism | Mice, Inbred C57BL | Janus Kinase 2 - genetics | Hematopoietic Stem Cells - metabolism | Myeloproliferative Disorders - drug therapy | Animals | Sulfonamides - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Bone Marrow - pathology | Heterozygote | Protein Kinase Inhibitors - pharmacology | Amino Acid Substitution | Megakaryocyte-Erythroid Progenitor Cells - pathology | Physiological aspects | Medical colleges | Analysis | Hematopoietic stem cells | Tumors
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2017, Volume 169, Issue 4, pp. 750 - 765.e17
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 2, p. e87893
...) is a key process by which cancer cells acquire invasive and metastatic phenotypes. In order to spawn macroscopic metastases, disseminated cancer cells would seem to require self-renewal capability... 
BREAST-CANCER | TRANSITION | MSCS | METASTASIS | FUSION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | FOCUS | IDENTIFICATION | TUMORS | PROGRESSION | Cell Proliferation | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Lung Neoplasms - pathology | Gene Expression Profiling | Epithelial-Mesenchymal Transition - genetics | Cell Fusion | Neoplastic Stem Cells - metabolism | Cell Shape | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Cell Differentiation | Fibroblasts - metabolism | Hybrid Cells - metabolism | Lung Neoplasms - genetics | Neoplasm Invasiveness | Spheroids, Cellular - metabolism | Bone Marrow Cells - pathology | Carcinogenesis - genetics | Mesenchymal Stromal Cells - metabolism | Epithelial Cells - pathology | Fibroblasts - pathology | Mice, SCID | Carcinogenesis - pathology | Phenotype | Animals | Hybrid Cells - pathology | Cell Line, Tumor | Mesenchymal Stromal Cells - pathology | Bone Marrow Cells - metabolism | Cell Movement | Lung cancer, Non-small cell | Development and progression | Metastasis | Vimentin | Hybrids | Transcription factors | Motility | Mesenchyme | Oct-4 protein | Brain cancer | Lung cancer | Cytology | Stem cell transplantation | Smooth muscle | Cell fusion | E-cadherin | Fibronectin | Metastases | Genotype & phenotype | Actin | Rodents | Bone marrow | Fibroblasts | Population | Subpopulations | Myeloid cells | Invasiveness | Muscles | Non-small cell lung carcinoma | Forming | Inflammation | Tumor cell lines | Gene expression | Medicine | Properties (attributes) | Bone cancer | Hospitals | Overexpression | Morphology | Stem cells | Aberration | Cancer
Journal Article
Cancer cell, ISSN 1535-6108, 2008, Volume 13, Issue 6, pp. 483 - 495
Faithful modeling of mixed-lineage leukemia in murine cells has been difficult to achieve... 
STEMCELL | CELLCYCLE | HEMATOPOIETIC-CELLS | B-CELLS | STEM-CELLS | ONCOLOGY | MLL REARRANGEMENTS | ACUTE LYMPHOBLASTIC-LEUKEMIA | ACUTE MYELOGENOUS LEUKEMIA | THERAPEUTIC TARGET | GENE-EXPRESSION PROFILES | ACUTE MYELOID-LEUKEMIA | FLT3 MUTATIONS | Translocation, Genetic | Antigens, CD34 - analysis | Myeloid-Lymphoid Leukemia Protein - metabolism | Cell Proliferation | Fetal Stem Cells - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Multipotent Stem Cells - metabolism | rac GTP-Binding Proteins - metabolism | Aneuploidy | Gene Expression Profiling | Stem Cell Transplantation | Neoplastic Stem Cells - metabolism | Time Factors | Cell Transformation, Neoplastic - genetics | rac GTP-Binding Proteins - genetics | Neoplastic Stem Cells - pathology | Cell Culture Techniques | Fetal Blood - immunology | Transduction, Genetic | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Genotype | Cell Lineage | Multipotent Stem Cells - pathology | Phenotype | Environment | Mice, Inbred NOD | Mice | Fetal Stem Cells - pathology | Oncogene Proteins, Fusion - metabolism | Species Specificity | Gene Expression Regulation, Neoplastic | Neoplastic Stem Cells - immunology | Multipotent Stem Cells - immunology | Fetal Stem Cells - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Leukemia, Experimental - pathology | Fetal Blood - metabolism | Mice, SCID | Cell Transformation, Neoplastic - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Myeloid-Lymphoid Leukemia Protein - genetics | Oncogene Proteins, Fusion - genetics | Chromosomes, Human, Pair 11 | Cell Transformation, Neoplastic - pathology | Cell Line, Transformed | Leukemia, Experimental - metabolism | Apoptosis | Leukemia, Myeloid, Acute - genetics | Cytogenetics | Models | Growth factors | Analysis | Leukemia | Stem cells
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2018, Volume 215, Issue 11, pp. 2936 - 2954
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 464, Issue 7290, pp. 852 - 857
Journal Article