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PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, pp. e0181461 - e0181461
Irisin is a myokine encoded in its precursor fibronectin type III domain containing 5 (FNDC5). It is abundantly expressed in cardiac and skeletal muscle, and... 
FNDC5 | MESSENGER-RNA EXPRESSION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MYOSTATIN | TROPONIN-T | SECRETORY ORGAN | HUMAN SKELETAL-MUSCLE | EXERCISE | ADIPOSE-TISSUE | Troponin T - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Zebrafish Proteins - metabolism | Down-Regulation | Heart - physiology | RNA, Messenger - genetics | Peptides - genetics | Muscle, Skeletal - metabolism | Peptides - deficiency | RNA, Messenger - metabolism | Troponin C - genetics | Zebrafish - genetics | Gene Knockdown Techniques | Zebrafish Proteins - deficiency | Animals | Peptides - metabolism | Zebrafish - metabolism | Myocytes, Cardiac - metabolism | Myostatin - genetics | Zebrafish - physiology | Zebrafish Proteins - genetics | Muscles | Physiological aspects | Myostatin | Messenger RNA | Research | Zebra fish | Veterinary colleges | Heart attacks | Laboratories | Cardiomyopathy | Tissues | Veterinary medicine | Modulators | Fibronectin | Proteins | Exercise | Coding | Rodents | Calcium-binding protein | Physiology | Heart diseases | Cardiovascular system | Cytokines | Cardiac muscle | Immunomodulation | Zebrafish | siRNA | Metabolism | Gene expression | Skeletal muscle | Heart rate | Musculoskeletal system | Troponin | Stem cells | Diabetes | Immunoreactivity | Cardiac output | In vitro methods and tests | Troponin C | Endocrinology | Index Medicus
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 2015, Volume 309, Issue 11, pp. H1947 - H1963
There are 160,000 cancer patients worldwide treated with particle radiotherapy (RT). With the advent of proton, and high (H) charge (Z) and energy (E) HZE... 
Gene expression molecular signaling | Cardiac physiology | Cardiomyocyte | Radiation biology | gene expression molecular signaling | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ATOMIC-BOMB SURVIVORS | ENDOTHELIAL DYSFUNCTION | MYOCARDIAL-INFARCTION | COMPLETE ATRIOVENTRICULAR-BLOCK | cardiac physiology | INDUCED HEART-DISEASE | GAMMA-IRRADIATION | radiation biology | TRANSCRIPTION FACTOR GATA4 | cardiomyocyte | PERIPHERAL VASCULAR DISEASE | ACTIVATED PROTEIN-KINASES | IONIZING-RADIATION | EXPRESSION CHANGES | Whole-Body Irradiation | Oligonucleotide Array Sequence Analysis | Transcription, Genetic - radiation effects | Male | Transcriptome - radiation effects | Time Factors | Signal Transduction - radiation effects | Real-Time Polymerase Chain Reaction | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Radiotherapy, High-Energy - adverse effects | GATA4 Transcription Factor - metabolism | Risk Assessment | Mice, Inbred C57BL | Cells, Cultured | GATA4 Transcription Factor - genetics | Gene Expression Profiling - methods | Iron Radioisotopes - toxicity | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - radiation effects | Fibrosis | Gene Expression Regulation - radiation effects | Gene Regulatory Networks - radiation effects | Myocytes, Cardiac - metabolism | Mitogen-Activated Protein Kinases - genetics | Enzyme Activation | Cluster Analysis | Mitogen-Activated Protein Kinases - metabolism | Analysis | Genes | Heart cells | Radiation | Physiological aspects | Genetic research | Cellular signal transduction | Gene expression | Ionizing radiation | Genetic aspects | Observations | Health aspects | Heart | Cardiomyocytes | Radiation therapy | Molecular biology | Cell cycle | Index Medicus | Signaling and Stress Response
Journal Article
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 04/2018, Volume 9
Cardiac myocyte contraction is initiated by a set of intricately orchestrated electrical impulses, collectively known as action potentials (APs). Voltage-gated... 
epilepsy | ANKYRIN-G | PHYSIOLOGY | DRAVET SYNDROME | BETA-1 SUBUNIT | MOLECULAR DETERMINANTS | FEBRILE SEIZURES | VENTRICULAR MYOCYTES | SUDDEN UNEXPECTED DEATH | BRUGADA-SYNDROME | sodium channel | electrophysiology | arrhythmia | cell adhesion | FUNCTIONAL EXPRESSION | NEURONAL EXCITABILITY | B subunit
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 34, pp. 13839 - 13844
The adult mammalian heart has limited potential for regeneration. Thus, after injury, cardiomyocytes are permanently lost, and contractility is diminished. In... 
Heart | Regeneration | Transcription factors | Ligation | Alleles | Fibrosis | Myocardium | Photoreceptors | Left coronary artery | Cardiac output | Cardiac fibrosis | Cardiomyopathy | Cell cycle | TRANSCRIPTION FACTORS | F-ACTIN | cell cycle | ORGAN SIZE CONTROL | MULTIDISCIPLINARY SCIENCES | CARDIOMYOCYTE PROLIFERATION | ZEBRAFISH HEART REGENERATION | MIR-15 FAMILY | TEAD/TEF FAMILY | cardiac fibrosis | SIGNALING PATHWAY | IN-VIVO | cardiomyopathy | HOLT-ORAM-SYNDROME | Echocardiography | Heart - physiology | Myocardial Contraction - physiology | Mice, Transgenic | DNA Primers - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Phosphoproteins - metabolism | Regeneration - physiology | Blotting, Western | Mutation, Missense - genetics | Tetrazolium Salts | Transcription Factors - metabolism | Myocardial Contraction - genetics | Animals | Histological Techniques | Myocytes, Cardiac - physiology | Adaptor Proteins, Signal Transducing - genetics | Myocytes, Cardiac - metabolism | Signal Transduction - physiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Protein-Serine-Threonine Kinases - metabolism | Proteins | Molecular genetics | Heart cells | Cellular control mechanisms | Physiological aspects | Genetic aspects | Regeneration (Biology) | Research | Signal transduction | Tissue engineering | Rodents | Cardiomyocytes | Insulin-like growth factors | Index Medicus | Biological Sciences
Journal Article
Circulation Research, ISSN 0009-7330, 07/2014, Volume 115, Issue 3, pp. 354 - 363
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2007, Volume 104, Issue 35, pp. 14068 - 14073
Journal Article