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Journal Article
Biomaterials, ISSN 0142-9612, 2006, Volume 27, Issue 28, pp. 4881 - 4893
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2004, Volume 24, Issue 12, pp. 2320 - 2325
OBJECTIVE—Atherosclerosis is a chronic inflammatory response of the arterial wall to injury. High-mobility group box 1 (HMGB1) is a DNA-binding protein, which... 
High-mobility group box 1 | Inflammation | Cytokines | Macrophages | Atherosclerosis | atherosclerosis | RHEUMATOID-ARTHRITIS | PROTEIN-KINASE-C | PHOSPHATIDYLINOSITOL 3-KINASE | IFN-GAMMA | VASCULAR-LESIONS | NECROSIS-FACTOR-ALPHA | macrophages | SMOOTH-MUSCLE | high-mobility group box 1 | inflammation | SIGNALING PATHWAY | PERIPHERAL VASCULAR DISEASE | cytokines | TNF-ALPHA | END-PRODUCTS RAGE | HEMATOLOGY | Endothelium, Vascular - cytology | Monocytes - cytology | Humans | Myocytes, Smooth Muscle - pathology | Monocytes - metabolism | Protein Transport - physiology | HMGB1 Protein - immunology | Aorta, Thoracic - chemistry | Cytokines - physiology | Endothelium, Vascular - chemistry | HMGB1 Protein - genetics | HMGB1 Protein - secretion | RNA, Messenger - biosynthesis | HMGB1 Protein - metabolism | Muscle, Smooth, Vascular - chemistry | Aorta, Abdominal - pathology | Aorta, Abdominal - metabolism | Inflammation Mediators - physiology | Myocytes, Smooth Muscle - metabolism | Aorta, Thoracic - pathology | Muscle, Smooth, Vascular - physiology | Tunica Intima - chemistry | Macrophage Activation - physiology | Macrophages - physiology | Tunica Intima - physiology | Cells, Cultured | Myocytes, Smooth Muscle - physiology | Aorta, Thoracic - metabolism | Gene Expression Regulation - physiology | Myocytes, Smooth Muscle - chemistry | Immunohistochemistry - methods | Monocytes - chemistry | Muscle, Smooth, Vascular - pathology | Tunica Intima - pathology | Aorta, Abdominal - chemistry | Endothelium, Vascular - pathology | Arteriosclerosis - metabolism | Arteriosclerosis - pathology
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2016, Volume 66, Issue 5, pp. 1553 - 1564.e6
Abstract Objective Abdominal aortic aneurysm (AAA) is a frequent, potentially life-threatening, disease that can only be treated by surgical means such as open... 
Surgery | SURGERY | MYOCARDIN | RISK-FACTORS | ABDOMINAL AORTIC-ANEURYSM | PHENOTYPIC MODULATION | INFLAMMATION | UNIQUE | PERIPHERAL VASCULAR DISEASE | PATHOPHYSIOLOGY | Inflammation - pathology | Vascular Remodeling | Humans | Myocytes, Smooth Muscle - pathology | Cell Dedifferentiation | Aortic Aneurysm, Abdominal - diagnostic imaging | Popliteal Artery - chemistry | Extracellular Matrix - chemistry | Aortic Aneurysm, Abdominal - metabolism | Extracellular Matrix Proteins - analysis | Aortography - methods | Inflammation - metabolism | Transforming Growth Factor beta - analysis | Aorta, Abdominal - diagnostic imaging | Inflammation Mediators - analysis | Kruppel-Like Transcription Factors - analysis | Muscle, Smooth, Vascular - chemistry | Aneurysm - diagnostic imaging | Aorta, Abdominal - pathology | Inflammation - diagnostic imaging | Dilatation, Pathologic | Aneurysm - metabolism | Aortic Aneurysm, Abdominal - pathology | Angiogenic Proteins - analysis | Biomarkers - analysis | Myocytes, Smooth Muscle - chemistry | Aneurysm - pathology | Popliteal Artery - diagnostic imaging | Computed Tomography Angiography | Muscle, Smooth, Vascular - pathology | Phenotype | Aorta, Abdominal - chemistry | Popliteal Artery - pathology | Extracellular Matrix - pathology | Medicine, Experimental | Aneurysms | Medical research | Cells | Immunohistochemistry | Endothelial growth factors | Analysis | Smooth muscle | Bone morphogenetic proteins
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2008, Volume 283, Issue 27, pp. 18505 - 18512
Smooth muscle contraction is initiated by a rise in intracellular calcium, leading to activation of smooth muscle myosin light chain kinase (MLCK) via... 
HEART | CATALYTIC SUBUNIT | CONTRACTION | CALMODULIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALCIUM | COMPONENTS | SITES | ISCHEMIA | IDENTIFICATION | CELL | Calmodulin - genetics | Myosin-Light-Chain Kinase - genetics | Rats, Wistar | Calcium - metabolism | Multienzyme Complexes - metabolism | Adenosine Triphosphate - genetics | Male | AMP-Activated Protein Kinases | Vasoconstriction - physiology | Phenylephrine - pharmacology | Cattle | Adenosine Triphosphate - metabolism | Potassium Chloride - pharmacology | Phosphorylation - drug effects | Aorta - enzymology | Myosin-Light-Chain Kinase - chemistry | Protein-Serine-Threonine Kinases - metabolism | Vasoconstrictor Agents - pharmacology | Muscle Tonus - physiology | Calmodulin - metabolism | Calcium-Calmodulin-Dependent Protein Kinases - genetics | Myocytes, Smooth Muscle - enzymology | Myosin-Light-Chain Kinase - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Rats | Multienzyme Complexes - genetics | Muscle Tonus - drug effects | Myocytes, Smooth Muscle - chemistry | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Vasoconstriction - drug effects | Muscle, Smooth - chemistry | Mice, Knockout | Multienzyme Complexes - chemistry | Calcium-Calmodulin-Dependent Protein Kinases - chemistry | Animals | Naphthalimides - pharmacology | Muscle Contraction - drug effects | Chickens | Muscle Contraction - physiology | Aorta - chemistry | Benzimidazoles - pharmacology | Mice | Protein-Serine-Threonine Kinases - chemistry | Adenosine Triphosphate - chemistry | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Muscle, Smooth - enzymology
Journal Article
Lab on a Chip, ISSN 1473-0197, 2018, Volume 18, Issue 13, pp. 1875 - 1883
Smooth muscle cell (SMC) heterogeneity plays an important role in vascular remodeling, a life-threatening hallmark of many vascular diseases. However, the... 
Journal Article
Journal Article