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Nature Cell Biology, ISSN 1465-7392, 02/2004, Volume 6, Issue 2, pp. 154 - 161
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2017, Volume 37, Issue 1, pp. 26 - 34
The importance of maintaining contractile function in aortic smooth muscle cells (SMCs) is evident by the fact that heterozygous mutations in the major... 
mutation | thoracic aorta | aortic aneurysm | aortic dissection | vascular smooth muscle cells | Marfan syndrome | LIGHT-CHAIN KINASE | ACTIN POLYMERIZATION | DOMAIN-STRUCTURE | TGFBR2 MUTATIONS | MYOSIN HEAVY-CHAIN | BETA RECEPTOR | MARFAN-SYNDROME | MOUSE MODEL | DISEASE | PERIPHERAL VASCULAR DISEASE | PATENT DUCTUS-ARTERIOSUS | HEMATOLOGY | Myosin-Light-Chain Kinase - genetics | Aneurysm, Dissecting - genetics | Aortic Aneurysm, Thoracic - genetics | Genetic Testing | Muscle, Smooth, Vascular - metabolism | Pulsatile Flow | Humans | Actins - metabolism | Myocytes, Smooth Muscle - pathology | Myosin Heavy Chains - genetics | Cyclic GMP-Dependent Protein Kinase Type I - genetics | Muscle, Smooth, Vascular - physiopathology | Myosin Heavy Chains - metabolism | Actins - genetics | Cyclic GMP-Dependent Protein Kinase Type I - metabolism | Aneurysm, Dissecting - physiopathology | Aortic Aneurysm, Thoracic - pathology | Dilatation, Pathologic | Myocytes, Smooth Muscle - metabolism | Calcium-Binding Proteins - metabolism | Vasoconstriction - genetics | Elastin - metabolism | Aneurysm, Dissecting - metabolism | Myosin-Light-Chain Kinase - metabolism | Heredity | Aneurysm, Dissecting - pathology | Genetic Markers | Aortic Aneurysm, Thoracic - physiopathology | Mechanotransduction, Cellular | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Aortic Aneurysm, Thoracic - metabolism | Mutation | Calcium-Binding Proteins - genetics | elastin-contractile unit | Contractile Function | Vascular Biology | Aneurysm | Genetics | vascular smooth muscle cell | Aortic Dissection | thoracic
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 16, pp. 12037 - 12046
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2011, Volume 30, Issue 4, pp. 636 - 651
Journal Article
Carcinogenesis, ISSN 0143-3334, 2012, Volume 33, Issue 5, pp. 976 - 985
Transforming growth factor-beta (TGF-beta) signaling regulates many diverse cellular activities through both canonical (SMAD-dependent) and non-canonical... 
ONCOLOGY | LEUCINE-RICH ALPHA-2-GLYCOPROTEIN | N-MYC | TUMOR-SUPPRESSOR | RECEPTOR | DIFFERENTIATION | MICRORNAS | MYOSIN-II | EXPRESSION | CANCER | CHROMOSOMAL IMBALANCES | Oncogene Proteins - genetics | Up-Regulation | Phosphorylation | Myosin Light Chains - genetics | Humans | Glycoproteins - metabolism | MicroRNAs - metabolism | Cell Movement - genetics | rho-Associated Kinases - antagonists & inhibitors | rho-Associated Kinases - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Neuroblastoma - pathology | Glycoproteins - genetics | Signal Transduction | Neoplasm Invasiveness | Down-Regulation | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Neuroblastoma - genetics | Glycoproteins - antagonists & inhibitors | Oncogene Proteins - metabolism | rho-Associated Kinases - genetics | Nuclear Proteins - metabolism | Transcription Factors - genetics | Disease Progression | Transcription Factors - metabolism | Transforming Growth Factor beta - genetics | Cell Line, Tumor | MicroRNAs - genetics | Myosin Light Chains - metabolism | Neuroblastoma - metabolism | Protein Processing, Post-Translational | Transforming Growth Factor beta - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | 1-Phosphatidylinositol 3-kinase | Biology, Genetics and Epigenetics
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5566
Pyruvate kinase M2 (PKM2) is expressed at high levels during embryonic development and tumour progression and is important for cell growth. However, it is not... 
ACTIVATION | INHIBITION | METABOLISM | MULTIDISCIPLINARY SCIENCES | PYRUVATE-KINASE M2 | DEGRADATION | ISOFORM | BETA-CATENIN | PROMOTES | LIGHT-CHAIN PHOSPHORYLATION | GENE-TRANSCRIPTION | Cell Cycle - genetics | Phosphorylation | Proto-Oncogene Proteins p21(ras) | Aurora Kinase B - metabolism | Myosin Light Chains - genetics | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | rho-Associated Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Cell Transformation, Neoplastic - genetics | Cytokinesis - physiology | Membrane Proteins - metabolism | Cardiac Myosins - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Amides - pharmacology | Proto-Oncogene Proteins - metabolism | Cell Proliferation - genetics | Pyruvate Kinase - metabolism | Membrane Proteins - genetics | Cardiac Myosins - genetics | HCT116 Cells | Carrier Proteins - antagonists & inhibitors | Brain Neoplasms - genetics | Thyroid Hormones - genetics | Carrier Proteins - genetics | Leupeptins - pharmacology | Pyruvate Kinase - antagonists & inhibitors | Animals | Carrier Proteins - metabolism | Membrane Proteins - antagonists & inhibitors | Mitosis - physiology | Mice, Nude | Thyroid Hormones - metabolism | Cell Line, Tumor | Mice | Myosin Light Chains - metabolism | Pyridines - pharmacology | RNA, Small Interfering | Pyruvate Kinase - genetics
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2009, Volume 179, Issue 3, pp. 194 - 204
Journal Article
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 7/2011, Volume 462, Issue 1, pp. 119 - 134
Journal Article