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Circulation Research, ISSN 0009-7330, 04/2016, Volume 118, Issue 7, pp. 1143 - 1150
This “Controversies in Cardiovascular Research” article evaluates the evidence for and against the hypothesis that the circulating blood level of growth... 
myocardium | myokines | pathological hypertrophy | aging | growth factors | GDF11 | CARDIAC & CARDIOVASCULAR SYSTEMS | ATROPHY | FAILURE | SKELETAL-MUSCLE | HYPERTROPHY | MYOSTATIN | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AGE | Recombinant Proteins - therapeutic use | Single-Blind Method | Cachexia - chemically induced | Humans | Myostatin - physiology | Growth Differentiation Factors - toxicity | Bone Morphogenetic Proteins - blood | Muscle, Skeletal - injuries | Growth Differentiation Factors - blood | Growth Differentiation Factors - deficiency | Bone Morphogenetic Proteins - toxicity | Muscles - pathology | Parabiosis | Muscular Diseases - physiopathology | Growth Differentiation Factors - pharmacology | Muscular Diseases - drug therapy | Myostatin - toxicity | Bone Morphogenetic Proteins - deficiency | Models, Animal | Myostatin - therapeutic use | Drug Evaluation, Preclinical | Bone Morphogenetic Proteins - pharmacology | Smad2 Protein - physiology | Growth Differentiation Factors - therapeutic use | Reproducibility of Results | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Myocardium - pathology | Muscle, Skeletal - physiology | Aging - pathology | Aging - blood | Regeneration - drug effects | Animals | Heart - drug effects | Recombinant Proteins - toxicity | Bone Morphogenetic Proteins - therapeutic use | Smad3 Protein - physiology | Hypertrophy | Index Medicus | Myokines | Aging | Pathological Hypertrophy | Growth Factors | Cytokines
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 28, pp. 43442 - 43460
Cachexia affects the majority of cancer patients, with currently no effective treatments. Cachexia is defined by increased fatigue and loss of muscle function... 
Chemotherapy | Mitochondria | Cachexia | Muscle wasting | MAPKs | SKELETAL-MUSCLE ATROPHY | 1ST-LINE TREATMENT | OXIDATIVE STRESS | UBIQUITIN-PROTEASOME SYSTEM | mitochondria | cachexia | chemotherapy | muscle wasting | METASTATIC COLORECTAL-CANCER | CELL BIOLOGY | COLON-CANCER | LUNG-CANCER | TUMOR-BEARING MICE | GENE-EXPRESSION | UP-REGULATION | Activin Receptors, Type II - metabolism | Up-Regulation | Cachexia - chemically induced | Humans | Male | Muscular Atrophy - chemically induced | Fluorouracil - therapeutic use | Body Composition - drug effects | Colorectal Neoplasms - drug therapy | Muscle Fatigue - drug effects | Muscle, Skeletal - drug effects | Leucovorin - therapeutic use | Flavonoids - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Cachexia - metabolism | Colorectal Neoplasms - metabolism | Camptothecin - analogs & derivatives | Cell Line | MAP Kinase Kinase 1 - antagonists & inhibitors | Camptothecin - therapeutic use | Mitochondria - metabolism | Myoblasts | Myostatin - antagonists & inhibitors | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice | Protein Kinase Inhibitors - pharmacology | Muscle, Skeletal - pathology | Organoplatinum Compounds - therapeutic use | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
Neurology, ISSN 0028-3878, 12/2014, Volume 83, Issue 24, pp. 2239 - 2246
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2010, Volume 391, Issue 3, pp. 1548 - 1554
Journal Article
Pharmacological Research, ISSN 1043-6618, 06/2013, Volume 72, pp. 9 - 24
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2016, Volume 237, pp. 1 - 13
Journal Article
Diabetologia, ISSN 0012-186X, 1/2012, Volume 55, Issue 1, pp. 183 - 193
Although myostatin-null (Mstn −/−) mice fail to accumulate fat in adipose tissue when fed a high-fat diet (HFD), little is known about the molecular... 
Fatty acid oxidation | White adipose tissue | Human Physiology | COX-2 | Prostaglandin | Metabolic Diseases | UCP1 | Internal Medicine | Brown adipose tissue | PPARβ | Medicine & Public Health | Myostatin | sActRIIB | SActRIIB | ADIPOCYTES | PPAR beta | DEFICIENT MICE | IIB RECEPTOR | INSULIN SENSITIVITY | SKELETAL-MUSCLE | NONSHIVERING THERMOGENESIS | ENERGY-EXPENDITURE | BETA SUPERFAMILY MEMBER | MASS | MUTATION | ENDOCRINOLOGY & METABOLISM | Lipolysis - drug effects | Diet, High-Fat - adverse effects | Male | Muscle, Skeletal - metabolism | Gene Expression Profiling | Molecular Targeted Therapy | RNA, Messenger - metabolism | Anti-Obesity Agents - therapeutic use | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Oxidation-Reduction - drug effects | Myostatin - genetics | Obesity - etiology | Myostatin - metabolism | Fatty Acids - metabolism | Activin Receptors, Type II - chemistry | Adiposity - drug effects | Mice, Inbred C57BL | Solubility | Adipose Tissue, Brown - pathology | Mice, Knockout | Myostatin - antagonists & inhibitors | Obesity - metabolism | Obesity - pathology | Gene Expression Regulation - drug effects | Muscle Proteins - genetics | Anti-Obesity Agents - chemistry | Animals | Obesity - prevention & control | Activin Receptors, Type II - therapeutic use | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Obesity | Medical colleges | Enzymes | Prostaglandins | Genes | Oxidation-reduction reaction | Genetic aspects | Mitochondrial DNA | Gene expression | Fatty acids | Index Medicus
Journal Article
Lancet Diabetes & Endocrinology, The, ISSN 2213-8587, 2015, Volume 3, Issue 12, pp. 948 - 957
Journal Article
Expert review of cardiovascular therapy, 02/2018, Volume 16, Issue 2, p. 133
Sarcopenia is a common feature, and affects 20-47% of patients with heart failure (HF). Sarcopenia is also an independent predictor of impaired functional... 
Heart Failure - complications | Sarcopenia - physiopathology | Exercise | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Humans | Dietary Supplements | Sarcopenia - therapy | Adrenergic beta-Antagonists - therapeutic use | Heart Failure - drug therapy | Myostatin - antagonists & inhibitors
Journal Article
Journal Article