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NATURE, ISSN 0028-0836, 01/2017, Volume 541, Issue 7637, pp. 371 - 371
Internal bases in mRNA can be subjected to modifications that influence the fate of mRNA in cells. One of the most prevalent modified bases is found at the 5'... 
DEMETHYLASE | METHYLOME | N-6-METHYLADENOSINE | ALKBH5 | PROTEIN | DATABASE | MULTIDISCIPLINARY SCIENCES | ARGONAUTE | CELL | SEQ | CLIP
Journal Article
by Wang, X and Feng, J and Xue, Y and Guan, ZY and Zhang, DL and Liu, Z and Gong, Z and Wang, Q and Huang, JB and Tang, C and Zou, TT and Yin, P
NATURE, ISSN 0028-0836, 06/2016, Volume 534, Issue 7608, pp. 575 - 575
Chemical modifications of RNA have essential roles in a vast range of cellular processes(1-3). N-6-methyladenosine (m(6)A) is an abundant internal modification... 
WIDESPREAD | N-6-METHYLADENOSINE | N6-METHYLADENOSINE | METHYLTRANSFERASE | MESSENGER-RNA METHYLATION | DNA | EPITRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | NUCLEAR-RNA | REVEALS
Journal Article
NATURE, ISSN 0028-0836, 12/2017, Volume 552, Issue 7683, pp. 126 - 126
N-6-methyladenosine (m(6)A) is an abundant internal RNA modification in both coding(1) and non-coding RNAs2,3 that is catalysed by the METTL3-METTL14... 
TRANSCRIPTION FACTORS | ATLAS | N-6-METHYLADENOSINE | ELEMENTS | MESSENGER-RNA TRANSLATION | METHYLATION | INHIBITION | MULTIDISCIPLINARY SCIENCES | TARGETS | BINDING | MURINE
Journal Article
CANCER CELL, ISSN 1535-6108, 04/2017, Volume 31, Issue 4, pp. 591 - 591
The dynamic and reversible N-6-methyladenosine (m(6)A) RNA modification installed and erased by N-6-methyltransferases and demethylases regulates gene... 
N-6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | TRANSCRIPTOME | ONCOLOGY | GLIOMA | CROSS-LINKING | NUCLEAR-RNA | BINDING PROTEIN HUR | TRANSLATION | PROMOTES | REVEALS | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 08/2017, Volume 548, Issue 7667, pp. 338 - 338
N-6-methyladenosine (m(6)A) is the most common and abundant messenger RNA modification, modulated by 'writers', 'erasers' and 'readers' of this mark(1,2). In... 
DEGRADATION DYNAMICS | N-6-METHYLADENOSINE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION REGULATION | RESOLUTION | UPDATE | MODEL | NAIVE
Journal Article
NATURE, ISSN 0028-0836, 03/2017, Volume 543, Issue 7646, pp. 573 - 573
Cell proliferation and survival require the faithful maintenance and propagation of genetic information, which are threatened by the ubiquitous sources of DNA... 
POLYMERASE-KAPPA | N-6-METHYLADENOSINE | LOCALIZATION | REPAIR | N6-METHYLADENOSINE | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | MOUSE | TRANSCRIPTION | POL-KAPPA | NUCLEAR-RNA
Journal Article
by Liu, N and Parisien, M and Dai, Q and Zheng, GQ and He, C and Pan, T
RNA, ISSN 1355-8382, 12/2013, Volume 19, Issue 12, pp. 1848 - 1856
N-6-methyladenosine (m(6)A) is the most abundant modification in mammalian mRNA and long noncoding RNA (lncRNA). Recent discoveries of two m(6)A demethylases... 
RNA modification | RECOGNITION | SEQUENCE SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUANTITATION | N-6-methyladenosine | RESIDUES | single nucleotide resolution
Journal Article
RNA, ISSN 1355-8382, 10/2018, Volume 24, Issue 10, pp. 1339 - 1350
N-6-methyladenosine (m(6)A) modifications in RNAs play important roles in regulating many different aspects of gene expression. While m(6)As can have direct... 
RNA modification | N6-METHYLADENOSINE | METHYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING | exoribonuclease | N-6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | STRUCTURAL BASIS | translation | ribosome | YTH domain | NUCLEAR-RNA | BINDING | N-6-methyladenosine (mA) | REVEALS
Journal Article
NATURE, ISSN 0028-0836, 05/2012, Volume 485, Issue 7397, pp. 201 - U84
An extensive repertoire of modifications is known to underlie the versatile coding, structural and catalytic functions of RNA, but it remains largely uncharted... 
HALF-LIFE | IN-VITRO | IMMUNOSPECIFIC RETENTION | MESSENGER-RNA | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | RIBONUCLEIC-ACID | NUCLEIC-ACID COMPLEXES | N-6-METHYLADENOSINE RESIDUES | METHYLATED CONSTITUENTS | FACTOR-ALPHA
Journal Article
by Cui, Q and Shi, HL and Ye, P and Li, L and Qu, QH and Sun, GQ and Sun, GH and Lu, ZK and Huang, Y and Yang, CG and Riggs, AD and He, C and Shi, YH
CELL REPORTS, ISSN 2211-1247, 03/2017, Volume 18, Issue 11, pp. 2622 - 2634
RNA modifications play critical roles in important biological processes. However, the functions of N-6-methyladenosine (m(6)A) mRNA modification in cancer... 
N-6-METHYLADENOSINE | ADENOSYL-L-METHIONINE | CANCER RISK | SUSCEPTIBILITY VARIANTS | METHYLTRANSFERASE | MESSENGER-RNA | SEX DETERMINATION | 5' TERMINUS | NUCLEAR-RNA | EXPRESSION | CELL BIOLOGY
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2016, Volume 113, Issue 14, pp. E2047 - E2056
N-6-methyladenosine (m(6)A) modification of mRNA plays a role in regulating embryonic stem cell pluripotency. However, the physiological signals that determine... 
TUMOR HYPOXIA | MULTIDISCIPLINARY SCIENCES | hypoxia-inducible factors | self-renewal | CHEMOTHERAPY | pluripotency factors | DEMETHYLASE | INDUCIBLE FACTORS | N-6-METHYLADENOSINE | MAINTENANCE | FACTOR-1 | metastasis | tumorigenesis | EXPRESSION
Journal Article
Annual Review of Genetics, ISSN 0066-4197, 11/2018, Volume 52, Issue 1, pp. 349 - 372
Journal Article
NATURE, ISSN 0028-0836, 12/2016, Volume 540, Issue 7632, pp. 242 - 242
N-6-methyladenosine RNA (m(6)A) is a prevalent messenger RNA modification in vertebrates. Although its functions in the regulation of post-transcriptional gene... 
N-6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | GENE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAMMALIAN RNA | NUCLEAR-RNA | SACCHAROMYCES-CEREVISIAE | EXPRESSION | CENTRAL COMPLEX | REVEALS
Journal Article
by Li, XY and Xiong, XS and Wang, K and Wang, LX and Shu, XT and Ma, SQ and Yi, CQ
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 05/2016, Volume 12, Issue 5, pp. 311 - 311
N-1-Methyladenosine (m(1)A) is a prevalent post-transcriptional RNA modification, yet little is known about its abundance, topology and dynamics in mRNA. Here,... 
N-6-METHYLADENOSINE | N6-METHYLADENOSINE | METHYLTRANSFERASE | MESSENGER-RNA METHYLATION | OXIDATIVE DEMETHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR-RNA | BASE MODIFICATION | RIBOSOMAL-RNA | ALKYLATION DAMAGE | 1-METHYLADENOSINE
Journal Article
by Wen, J and Lv, RT and Ma, HH and Shen, HJ and He, CX and Wang, JH and Jiao, FF and Liu, H and Yang, PY and Tan, L and Lan, F and Shi, YJGN and He, C and Shi, Y and Diao, JB
MOLECULAR CELL, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 1028 - 1028
N-6-methyladenosine (m(6)A) is an abundant modification in eukaryotic mRNA, regulating mRNA dynamics by influencing mRNA stability, splicing, export, and... 
TRANSITION | N-6-METHYLADENOSINE | NUCLEOTIDES | N6-METHYLADENOSINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEX DETERMINATION | IDENTIFICATION | TRANSLATION | DROSOPHILA | PRE-MESSENGER-RNA | REVEALS | CELL BIOLOGY
Journal Article
SCIENCE, ISSN 0036-8075, 01/2019, Volume 363, Issue 6423, pp. 141 - 141
N-6-methyladenosine (m(6)A), a major modification of messenger RNAs (mRNAs), plays critical roles in RNA metabolism and function. In addition to the internal... 
N-6-METHYLADENOSINE | METHYLATION | PROTEIN | MESSENGER-RNA | MA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | GENE-EXPRESSION | TRANSLATION INITIATION | MECHANISMS | BINDING
Journal Article
NATURE, ISSN 0028-0836, 03/2018, Volume 555, Issue 7695, pp. 256 - 256
The TGF beta pathway has essential roles in embryonic development, organ homeostasis, tissue repair and disease(1,2). These diverse effects are mediated... 
N-6-METHYLADENOSINE | PROTEIN INTERACTIONS | QUANTITATIVE PROTEOMICS | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | TRANSCRIPTION | DEFINITIVE ENDODERM | NANOG | DIFFERENTIATION | TRANSLATION
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 02/2018, Volume 14, Issue 2
Polyomaviruses are a family of small DNA tumor viruses that includes several pathogenic human members, including Merkel cell polyomavirus, BK virus and JC... 
N6-METHYLADENOSINE | METHYLATION | SEQUENCES | MICROBIOLOGY | IDENTIFICATION | TRANSLATION | HYDROLASE | N-6-METHYLADENOSINE | SARCOMA-VIRUS | VIROLOGY | 3-DEAZAADENOSINE | INFECTION | PARASITOLOGY
Journal Article
by Chen, K and Lu, ZK and Wang, X and Fu, Y and Luo, GZ and Liu, N and Han, DL and Dominissini, D and Dai, Q and Pan, T and He, C
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 01/2015, Volume 54, Issue 5, pp. 1587 - 1590
N-6-methyladenosine (m(6)A) is an abundant internal modification in eukaryotic mRNA and plays regulatory roles in mRNA metabolism. However, methods to... 
RNA modification | N6-METHYLADENOSINE | IMMUNOSPECIFIC RETENTION | PAR-CLIP | N-6-methyladenosine | photo-crosslinking | BINDING PROTEIN | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | transcriptome sequencing | MESSENGER-RNA METHYLATION | SITES | RIBONUCLEIC-ACID | NUCLEIC-ACID COMPLEXES | REVEALS
Journal Article
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