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Addiction, ISSN 0965-2140, 2014, Volume 109, Issue 8, pp. 1338 - 1352
Aims To perform wastewater analyses to assess spatial differences and temporal changes of illicit drug use in a large European population. Design Analyses of... 
drugs of abuse | Amphetamine | cocaine | methamphetamine | ecstasy | cannabis | sewage | Ecstasy | Cannabis | Sewage | Methamphetamine | Cocaine | Drugs of abuse | METABOLITES | AUSTRALIA | PHARMACEUTICALS | PSYCHIATRY | SEWAGE WATER | CITIES | SUBSTANCE ABUSE | ABUSE | SYSTEMS | CONSUMPTION | Substance Abuse Detection - methods | Cocaine - metabolism | Humans | Sewage - analysis | Street Drugs - metabolism | Time Factors | Substance-Related Disorders - epidemiology | Mass Spectrometry | Waste Disposal, Fluid - statistics & numerical data | Amphetamines - analysis | Chromatography, Liquid | Cannabinoids - metabolism | Street Drugs - analysis | Cocaine - analysis | Sewage - chemistry | Substance-Related Disorders - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - analysis | Environmental Monitoring - methods | Europe - epidemiology | Water Pollutants, Chemical - chemistry | Substance Abuse Detection - statistics & numerical data | Water Pollutants, Chemical - analysis | Methamphetamine - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Methamphetamine - analysis | Waste Disposal, Fluid - methods | Amphetamines - metabolism | Environmental Monitoring - statistics & numerical data | Cannabinoids - analysis | Population Surveillance | Drug abuse | Purification | Analysis | Illegal drugs | Marijuana | Liquid chromatography | Wastewater | Mass spectrometry | Methamphetamines | Water treatment | Drug use | Research Reports | Medical and Health Sciences | Medicin och hälsovetenskap | Beroendelära | Hälsovetenskaper | Substance Abuse | Health Sciences
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2008, Volume 154, Issue 2, pp. 358 - 368
Journal Article
Science, ISSN 0036-8075, 9/2002, Volume 297, Issue 5590, pp. 2260 - 2263
The prevailing view is that the popular recreational drug (±)3,4-methyl-enedioxymethamphetamine (MDMA, or "ecstasy") is a selective serotonin neurotoxin in... 
Brain | Axons | Neurotoxicity | Animals | Caudate nucleus | Neurons | Humans | Primates | Reports | Dosage | Synapses | METABOLITES | COGNITIVE PERFORMANCE | METHYLENEDIOXYMETHAMPHETAMINE MDMA | RAT | RHESUS-MONKEYS | MULTIDISCIPLINARY SCIENCES | 3,4-METHYLENEDIOXYMETHAMPHETAMINE | HUMANS | SYSTEMS | CENTRAL SEROTONERGIC NEURONS | BRAIN | Tyrosine 3-Monooxygenase - metabolism | Membrane Glycoproteins - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - adverse effects | Motor Activity - drug effects | Male | Serotonin Plasma Membrane Transport Proteins | Corpus Striatum - metabolism | Corpus Striatum - ultrastructure | Brain - metabolism | Axons - ultrastructure | Brain - ultrastructure | Tremor - chemically induced | Female | Membrane Transport Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Dopamine - metabolism | Dopamine Plasma Membrane Transport Proteins | Hallucinogens - adverse effects | N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage | 3,4-Dihydroxyphenylacetic Acid - metabolism | Hallucinogens - administration & dosage | Hallucinogens - toxicity | Axons - drug effects | Axons - metabolism | Saimiri | Hydroxyindoleacetic Acid - metabolism | Nerve Tissue Proteins | Parkinsonian Disorders - chemically induced | Symporters - metabolism | Brain - drug effects | Papio | Autoradiography | Norepinephrine Plasma Membrane Transport Proteins | Carrier Proteins - metabolism | Norepinephrine - metabolism | Serotonin - metabolism | Corpus Striatum - drug effects | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Nerve Degeneration | Drug abuse | Parkinson's disease | Serotonin | Depression, Mental | Research | Squirrel monkeys | Risk factors | Neurotoxic agents | Ecstasy | Neurology | Side effects
Journal Article
Therapeutic Drug Monitoring, ISSN 0163-4356, 04/2004, Volume 26, Issue 2, pp. 137 - 144
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0179199 - e0179199
Background Ecstasy (Ec) use produces hyperthermia, excessive sweating, intense thirst, an inappropriate antidiuretic hormone secretion (SIADH) and a... 
IN-VITRO | TEMPERATURE | MDMA ECSTASY | MULTIDISCIPLINARY SCIENCES | HYPONATREMIA | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | VASOPRESSIN | DYSFUNCTION | Free Radical Scavengers - pharmacology | Reactive Oxygen Species - metabolism | Rats, Wistar | Glutathione - metabolism | Male | Epithelial Sodium Channels - metabolism | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Kidney - metabolism | Kidney Tubules, Collecting - drug effects | Solute Carrier Family 12, Member 1 - metabolism | Kidney - drug effects | Hallucinogens - toxicity | Water - metabolism | Thiobarbituric Acid Reactive Substances - metabolism | Blotting, Western | Rhabdomyolysis - prevention & control | Aquaporin 2 - metabolism | Kidney Tubules, Collecting - metabolism | Animals | Acetylcysteine - pharmacology | Muscle Fibers, Skeletal - pathology | Rhabdomyolysis - chemically induced | Allopurinol - pharmacology | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Oxidative Stress - drug effects | Oxidative stress | Care and treatment | Patient outcomes | Allopurinol | Acetylcysteine | Dosage and administration | Rhabdomyolysis | Health aspects | Ecstasy | Reactive oxygen species | Nephrology | Laboratories | Toxicity | Lithium | MDMA | Allografts | Metabolites | Rodents | Chlorides | Rheumatism | Water absorption | Thiobarbituric acid | Thirst | Damage | Aquaporin 2 | Glutathione | Urine | Medical research | Edema | Sweating | Hyponatremia | Kidneys | Secretion | Ducts | Rats | Vasopressin | Medicine | Inhibitors | Sodium | Amphetamines | Hyperthermia | Potassium | Transporter | Index Medicus
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 1/2017, Volume 390, Issue 1, pp. 15 - 24
3,4-Methylenedioxy-N-methylamphetamine (MDMA) has been shown to be effective in the treatment of post-traumatic stress disorder (PTSD) in numerous clinical... 
Neurosciences | Biomedicine | Monoamine receptors | Neurochemical profile | MDMA analogues | Monoamine transporters | Pharmacology/Toxicology | 3,4-Methylenedioxy- N -methylamphetamine (MDMA) | 3,4-Methylenedioxy-N-methylamphetamine (MDMA) | POSTTRAUMATIC-STRESS-DISORDER | NICOTINIC RECEPTORS | NOREPINEPHRINE | ECSTASY | DRUGS | DOPAMINE | PHARMACOLOGY & PHARMACY | 3,4-METHYLENEDIOXYMETHAMPHETAMINE-ASSISTED PSYCHOTHERAPY | SEROTONIN | INDUCED NEUROTOXICITY | UP-REGULATION | Tyrosine 3-Monooxygenase - metabolism | Vesicular Monoamine Transport Proteins - metabolism | Receptors, Serotonin, 5-HT2 - chemistry | Stress Disorders, Post-Traumatic - metabolism | Humans | Neurotransmitter Uptake Inhibitors - pharmacology | Benzofurans - pharmacology | Serotonin 5-HT2 Receptor Agonists - pharmacology | Receptors, Serotonin, 5-HT2 - drug effects | Structure-Activity Relationship | Receptors, Serotonin, 5-HT2 - metabolism | Neurotransmitter Uptake Inhibitors - metabolism | Benzofurans - chemistry | Catechol O-Methyltransferase - metabolism | Monoamine Oxidase - chemistry | Indoles - metabolism | Tyrosine 3-Monooxygenase - chemistry | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Indoles - pharmacology | N-Methyl-3,4-methylenedioxyamphetamine - chemistry | Radioligand Assay | Serotonin 5-HT2 Receptor Agonists - metabolism | Binding Sites | Monoamine Oxidase Inhibitors - pharmacology | Vesicular Monoamine Transport Proteins - chemistry | Vesicular Monoamine Transport Proteins - antagonists & inhibitors | Serotonin 5-HT2 Receptor Agonists - chemistry | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Neurotransmitter Uptake Inhibitors - chemistry | Monoamine Oxidase Inhibitors - metabolism | Protein Binding | Protein Conformation | Monoamine Oxidase Inhibitors - chemistry | Catechol O-Methyltransferase - chemistry | Indoles - chemistry | Benzofurans - metabolism | Monoamine Oxidase - metabolism | Monoamine oxidase | Batteries | Methamphetamine | Ecstasy (Drug) | Resveratrol | Post-traumatic stress disorder
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2012, Volume 37, Issue 5, pp. 1192 - 1203
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2007, Volume 189, Issue 4, pp. 489 - 503
3,4-Methylenedioxymethamphetamine (MDMA, designated as “Ecstasy” if illicitly marketed in tablet form) induces significant decrements in neuronal serotonin... 
Ecstasy | Biomedicine | Dopamine | Serotonin | Reuptake inhibitors | Transporters | Norepinephrine | Pharmacology/Toxicology | Trace amine receptors | Psychiatry | Monoamines | MDMA | norepinephrine | NONHUMAN-PRIMATES | SUBSTITUTED AMPHETAMINES | transporters | PSYCHIATRY | ecstasy | TRACE AMINES | MONOAMINE TRANSPORTERS | trace amine receptors | NEUROSCIENCES | serotonin | METHYLENEDIOXYMETHAMPHETAMINE MDMA | RAT-BRAIN SLICES | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | PARA-CHLOROAMPHETAMINE | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | reuptake inhibitors | dopamine | ABUSED DRUG MDMA | monoamines | Dopamine Plasma Membrane Transport Proteins - metabolism | Temperature | Dopamine Plasma Membrane Transport Proteins - drug effects | Stereoisomerism | Humans | Brain - metabolism | Dose-Response Relationship, Drug | Serotonin Agents - toxicity | Serotonin Plasma Membrane Transport Proteins - drug effects | Transfection | N-Methyl-3,4-methylenedioxyamphetamine - chemistry | Dopamine - metabolism | Binding, Competitive | Cell Line | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Serotonin Agents - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - genetics | Brain - drug effects | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Neurotoxicity Syndromes - etiology | Serotonin Plasma Membrane Transport Proteins - metabolism | Norepinephrine - metabolism | Norepinephrine Plasma Membrane Transport Proteins - drug effects | Serotonin Agents - chemistry | Serotonin - metabolism | Neurotoxicity Syndromes - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Kinetics | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - drug effects | Primates | Brain | Neurotransmitters | Neurotoxicity | Neurons
Journal Article
Neurotoxicology, ISSN 0161-813X, 01/2013, Volume 34, Issue 1, pp. 254 - 263
► “Ecstasy” (MDMA) and DOI promoted neurotoxicity in a time- and concentration-dependent manner in cultured hippocampus neurons. ► MDMA and DOI mediated... 
Amphetamines | Caspases | Hallucinogens | Hippocampus | 5-HT2A-receptors | AIF | MDMA | DOI | Apoptosis | receptors | 5-HT | COGNITIVE PERFORMANCE | RAT CORTICAL-NEURONS | MEMORY IMPAIRMENT | NEUROSCIENCES | CELL-DEATH | MDMA ECSTASY | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DENTATE GYRUS | USERS | BRAIN-SEROTONIN NEURONS | L-Lactate Dehydrogenase - metabolism | Neurons - pathology | Rats, Wistar | Caspase 3 - metabolism | Caspase 8 - metabolism | Hippocampus - drug effects | Dose-Response Relationship, Drug | Neurotoxicity Syndromes - pathology | Time Factors | Neurons - metabolism | Receptor, Serotonin, 5-HT2A - drug effects | Neurons - drug effects | Apoptosis Inducing Factor - metabolism | Biomarkers - metabolism | Cell Survival - drug effects | Hippocampus - embryology | Hallucinogens - toxicity | Cytochromes c - metabolism | Cells, Cultured | Rats | Hippocampus - pathology | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Gestational Age | Blotting, Western | Neurotoxicity Syndromes - etiology | Hippocampus - metabolism | Animals | Amphetamines - toxicity | Neurotoxicity Syndromes - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Primary Cell Culture | Receptor, Serotonin, 5-HT2A - metabolism | Cytochrome c | Neurosciences | Universities and colleges | Neurons | Methamphetamine | Ecstasy (Drug) | Neurologi | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Neurology
Journal Article