X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1480) 1480
humans (1341) 1341
n-myc (889) 889
neuroblastoma (740) 740
oncology (720) 720
n-myc proto-oncogene protein (669) 669
neuroblastoma - genetics (642) 642
animals (560) 560
nuclear proteins - genetics (552) 552
oncogene proteins - genetics (538) 538
neuroblastoma - pathology (513) 513
expression (432) 432
cell line, tumor (429) 429
mice (409) 409
cancer (394) 394
female (367) 367
neuroblastoma - metabolism (363) 363
gene amplification (349) 349
c-myc (348) 348
cell biology (342) 342
male (329) 329
infant (315) 315
prognosis (313) 313
tumors (300) 300
gene expression regulation, neoplastic (299) 299
biochemistry & molecular biology (292) 292
child (279) 279
child, preschool (267) 267
mycn (266) 266
gene expression (253) 253
apoptosis (248) 248
proto-oncogene proteins c-myc - genetics (247) 247
amplification (246) 246
nuclear proteins - metabolism (237) 237
differentiation (222) 222
proto-oncogene proteins c-myc - metabolism (217) 217
oncogene proteins - metabolism (213) 213
gene (183) 183
genetics & heredity (180) 180
research (180) 180
tumor cells, cultured (171) 171
cell proliferation (166) 166
genetic aspects (165) 165
proteins (159) 159
genes (156) 156
neoplasms (155) 155
pediatrics (155) 155
genes, myc (147) 147
neuroblastoma - drug therapy (144) 144
article (139) 139
cells (137) 137
gene-expression (135) 135
reverse transcriptase polymerase chain reaction (129) 129
neuroblastoma - mortality (127) 127
signal transduction (127) 127
neoplasm staging (123) 123
oncogene (121) 121
cell cycle (120) 120
analysis (119) 119
pathology (119) 119
mice, transgenic (118) 118
n-myc proto-oncogene protein - genetics (118) 118
adolescent (116) 116
mutation (114) 114
myc (113) 113
growth (112) 112
proto-oncogene proteins - genetics (110) 110
rna, messenger - genetics (110) 110
cell differentiation (109) 109
transfection (109) 109
infant, newborn (104) 104
immunohistochemistry (101) 101
protein (101) 101
blotting, western (100) 100
risk factors (97) 97
molecular sequence data (94) 94
gene expression profiling (92) 92
biology (91) 91
in situ hybridization, fluorescence (91) 91
base sequence (90) 90
health aspects (90) 90
transcription, genetic (90) 90
apoptosis - drug effects (89) 89
multidisciplinary sciences (88) 88
in-vivo (86) 86
research article (86) 86
oncogenes (84) 84
physiological aspects (84) 84
proliferation (84) 84
transgenic mice (83) 83
phosphorylation (82) 82
rna, messenger - metabolism (82) 82
genetics (81) 81
neuro-blastoma (81) 81
progression (81) 81
n-myc proto-oncogene protein - metabolism (80) 80
chemotherapy (79) 79
children (79) 79
neuroblastoma - diagnosis (79) 79
proto-oncogene proteins c-myc - physiology (79) 79
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
by Kool, Marcel and Jones, David T.W and Jäger, Natalie and Northcott, Paul A and Pugh, Trevor J and Hovestadt, Volker and Piro, Rosario M and Esparza, L. Adriana and Markant, Shirley L and Remke, Marc and Milde, Till and Bourdeaut, Franck and Ryzhova, Marina and Sturm, Dominik and Pfaff, Elke and Stark, Sebastian and Hutter, Sonja and Şeker-Cin, Huriye and Johann, Pascal and Bender, Sebastian and Schmidt, Christin and Schmidt, Sabine and Rausch, Tobias and Shih, David and Reimand, Jüri and Sieber, Laura and Wittmann, Andrea and Linke, Linda and Witt, Olaf and Witt, Hendrik and Weber, Ursula D and Zapatka, Marc and König, Rainer and Beroukhim, Rameen and Bergthold, Guillaume and van Sluis, Peter and Volckmann, Richard and Koster, Jan and Versteeg, Rogier and Wolf, Stephan and Lawerenz, Chris and Bartholomae, Cynthia C and von Kalle, Christof and Unterberg, Andreas and Herold-Mende, Christel and Hofer, Silvia and Kulozik, Andreas E and von Deimling, Andreas and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Hasselblatt, Martin and Crawford, John R and Grant, Gerald A and Jabado, Nada and Perry, Arie and Cowdrey, Cynthia and Croul, Sydney and Zadeh, Gelareh and Korbel, Jan O and Doz, Francois and Delattre, Olivier and Bader, Gary D and McCabe, Martin G and Collins, V. Peter and Kieran, Mark W and Cho, Yoon-Jae and Pomeroy, Scott L and Brors, Benedikt and Taylor, Michael D and Schüller, Ulrich and Korshunov, Andrey and Eils, Roland and Wechsler-Reya, Robert J and Lichter, Peter and Pfister, Stefan M and ICGC PedBrain Tumor Project
Cancer Cell, ISSN 1535-6108, 03/2014, Volume 25, Issue 3, pp. 393 - 405
Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven medulloblastoma (SHH-MB). Clinical response is highly variable. To... 
NERVOUS-SYSTEM | TERT PROMOTER MUTATIONS | ONCOLOGY | GROWTH | HEDGEHOG PATHWAY INHIBITOR | ITRACONAZOLE | PEDIATRIC MEDULLOBLASTOMA | CANCER | TUMORS | MOUSE MODELS | ADULT | CELL BIOLOGY | Neoplasm Transplantation | Oncogene Proteins - genetics | Humans | Zinc Finger Protein Gli2 | Child, Preschool | Molecular Sequence Data | Infant | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - therapeutic use | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Young Adult | Telomerase - genetics | Hedgehog Proteins - genetics | Base Sequence | Smoothened Receptor | Adult | Female | N-Myc Proto-Oncogene Protein | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Child | Pyridines - therapeutic use | Cerebellar Neoplasms - drug therapy | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Cerebellar Neoplasms - genetics | Mice, SCID | Phosphatidylinositol 3-Kinases - genetics | DEAD-box RNA Helicases - genetics | Drug Resistance, Neoplasm - genetics | Animals | Adolescent | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice, Inbred NOD | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Genetic aspects | Nucleotide sequencing | Analysis | Medulloblastoma | Genomics | DNA sequencing | Index Medicus
Journal Article
Journal Article
Nature genetics, ISSN 1061-4036, 2012, Volume 44, Issue 11, pp. 1199 - 1206
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 700 - 704
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2016, Volume 30, Issue 4, pp. 563 - 577
The transition from castration-resistant prostate adenocarcinoma (CRPC) to neuroendocrine prostate cancer (NEPC) has emerged as an important mechanism of... 
castration-resistant prostate adenocarcinoma | prostate cancer organoid | N-Myc | genetically engineered mouse | neuroendocrine prostate cancer | Aurora kinase A | EZH2 | REARRANGEMENT | INACTIVATION | GENOMICS | PROTEIN | ONCOLOGY | ADENOCARCINOMA | MOUSE MODEL | SMALL-CELL CARCINOMA | PTEN | DIFFERENTIATION | IDENTIFICATION | CELL BIOLOGY | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Prostatic Neoplasms - metabolism | Humans | N-Myc Proto-Oncogene Protein - genetics | Male | Genes, myc | Prostatic Neoplasms, Castration-Resistant - genetics | Prostatic Neoplasms, Castration-Resistant - pathology | Heterografts | Prostatic Neoplasms - genetics | Transcription, Genetic | N-Myc Proto-Oncogene Protein - biosynthesis | Prostatic Neoplasms - drug therapy | Neuroendocrine Tumors - pathology | Prostatic Neoplasms - pathology | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Signal Transduction | Neuroendocrine Tumors - metabolism | Mice, Transgenic | Prostatic Neoplasms, Castration-Resistant - drug therapy | Pyrimidines - pharmacology | Prostatic Neoplasms, Castration-Resistant - metabolism | Neuroendocrine Tumors - genetics | Azepines - pharmacology | Animals | N-Myc Proto-Oncogene Protein - metabolism | Neuroendocrine Tumors - drug therapy | Mice | Protein Kinase Inhibitors - pharmacology | Development and progression | Genetic aspects | Genetic engineering | Genetic transcription | Prostate cancer | Genetically modified organisms | Index Medicus
Journal Article
Cancer Discovery, ISSN 2159-8274, 03/2013, Volume 3, Issue 3, pp. 309 - 323
Bromodomain inhibition comprises a promising therapeutic strategy in cancer, particularly for hematologic malignancies. To date, however, genomic biomarkers to... 
ANAPLASTIC LYMPHOMA KINASE | CELL LUNG-CANCER | DRUG-SENSITIVITY | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | THERAPEUTIC TARGET | N-MYC | C-MYC | ALK KINASE | ACUTE MYELOID-LEUKEMIA | ACTIVATING MUTATIONS | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Apoptosis - drug effects | Humans | Transcription Factors - deficiency | Apoptosis - genetics | Molecular Targeted Therapy | Transfection | Nuclear Proteins - deficiency | Cell Cycle Checkpoints - genetics | Female | N-Myc Proto-Oncogene Protein | Cell Growth Processes - genetics | Nuclear Proteins - genetics | Child | Neuroblastoma - pathology | Protein Structure, Tertiary | Promoter Regions, Genetic | Neuroblastoma - genetics | Oncogene Proteins - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Down-Regulation - drug effects | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Gene Amplification | Cell Cycle Checkpoints - drug effects | Neuroblastoma - drug therapy | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Neuroblastoma - metabolism | Proto-Oncogene Proteins c-myc - genetics | RNA, Small Interfering - administration & dosage | Index Medicus | neuroblastoma | BET bromodomain inhibitor | MYCN | JQ1 | BRD4
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 247 - 256
MicroRNAs (miRNAs) are increasingly implicated in regulating the malignant progression of cancer. Here we show that miR-9, which is upregulated in breast... 
ADHESION | STEM-CELLS | INVASION | N-MYC | C-MYC | TUMOR ANGIOGENESIS | HUMAN BREAST-CANCER | MESENCHYMAL TRANSITION | EXPRESSION | MAMMARY EPITHELIAL-CELLS | CELL BIOLOGY | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Protein Binding - genetics | Cell Proliferation | MicroRNAs - antagonists & inhibitors | Cadherins - metabolism | Gene Expression - genetics | Humans | 3' Untranslated Regions - genetics | Vascular Endothelial Growth Factor A - genetics | N-Myc Proto-Oncogene Protein | Cadherins - genetics | Oncogene Proteins - metabolism | Vascular Endothelial Growth Factor A - blood | Epithelial Cells - pathology | DNA - metabolism | Neuroblastoma - diagnosis | beta Catenin - metabolism | Down-Regulation - genetics | Cell Line, Tumor | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Neuroblastoma - metabolism | Proto-Oncogene Proteins c-myc - genetics | Histones - metabolism | MicroRNAs - physiology | Neoplasms - metabolism | Epithelial Cells - metabolism | Vimentin - metabolism | Lung Neoplasms - pathology | Breast Neoplasms - metabolism | Neovascularization, Pathologic - pathology | Neoplasms - blood | Transfection | Lung Neoplasms - secondary | Neoplasm Invasiveness - pathology | Female | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Neuroblastoma - pathology | Cell Line | Neuroblastoma - genetics | Nuclear Proteins - metabolism | Gene Dosage | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | beta Catenin - genetics | Neoplasm Metastasis - genetics | Animals | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Signal Transduction - physiology | Transplantation, Heterologous - pathology | Neoplasm Invasiveness - genetics | Neoplasms - pathology | MicroRNA | Physiological aspects | Cadherins | Development and progression | Genetic aspects | Metastasis | Research | Oncogenes | Index Medicus
Journal Article