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Journal of Investigative Dermatology, ISSN 0022-202X, 04/2019, Volume 139, Issue 4, pp. 756 - 759
Large-giant congenital melanocytic nevi have been well characterized clinically, yet questions remain about the heterogenous phenotypes observed. Martins da... 
N-RAS | MELANOMA | DERMATOLOGY
Journal Article
by Shi, HB and Kong, XJ and Ribas, A and Lo, RS
CANCER RESEARCH, ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5067 - 5074
B-V600E-RAF mutation is found in 50% to 60% of melanomas, and the novel agents PLX4032/vemurafenib and GSK2118436 that inhibit the B-V600E-RAF kinase achieve a... 
SIGNALING PATHWAYS | ACTIVATION | MEK | ONCOLOGY | N-RAS | IN-VIVO | ACQUIRED-RESISTANCE | BRAF | AKT | VIVO ANTITUMOR-ACTIVITY | HUMAN CANCER
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 03/2016, Volume 22, Issue 9, pp. 2771 - 2778
Journal Article
Cancer Research, ISSN 0008-5472, 05/2012, Volume 72, Issue 10, pp. 2457 - 2467
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 09/2019, Volume 55, Issue 75, pp. 11183 - 11186
Reversible S-palmitoylation is a key regulatory mechanism of protein function and localization. There is increasing evidence that S-acylation is not restricted... 
IDENTIFICATION | CHROMATOGRAPHY | N-RAS | ASSOCIATION | CHEMISTRY, MULTIDISCIPLINARY | REVEALS
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 01/2012, Volume 13, Issue 1, pp. 39 - 51
Journal Article
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 9, pp. 2244 - 2256
Combined treatment of metastatic melanoma with BRAF and MEK inhibitors has improved survival, but the emergence of resistance represents an important clinical... 
BRAF-MUTANT | ERK INHIBITOR | ONCOLOGY | N-RAS | PROTEIN-KINASE | GROWTH | ACQUIRED-RESISTANCE | CELL-PROLIFERATION | DRUG-RESISTANCE | MUTATIONS | EXPRESSION
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2016, Issue 9, pp. 2771 - 2778
AIM: To investigate the targeted inhibition of proliferation and migration of SW620 human colon cancer cells by upregulating mi RNA-145(mi R-145).METHODS:... 
cancer;Targeted | therapy;N-ras;Lentiviral | vector | mi | RNA-145;Colorectal
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2019, Volume 30, Issue 9, pp. 1108 - 1117
HRAS, NRAS, and KRAS isoforms are almost identical proteins that are ubiquitously expressed and activate a common set of effectors. In vivo studies have... 
ONCOGENIC K-RAS | REPLACEMENT | CELLS | H-RAS | N-RAS | PATHWAY | ACTIVATE RAF-1 | PROLIFERATION | MUTATIONS | CANCER | CELL BIOLOGY
Journal Article
British Journal of Dermatology, ISSN 0007-0963, 04/2011, Volume 164, Issue 4, pp. 776 - 784
Journal Article