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Tetrahedron Letters, ISSN 0040-4039, 12/2016, Volume 57, Issue 52, pp. 5924 - 5927
In our hands, access to 2 novel peptidomimetic scaffolds, based on -alkylated pyrroldin-2,5-diones and piperidin-2,6-diones, proved to be much more challenging... 
N-Alkylation | Piperidin-2,6-dione | Peptidomimetics
Journal Article
Nature Communications, ISSN 2041-1723, 11/2014, Volume 5, Issue 1, p. 5602
The selective conversion of carbon-oxygen bonds into carbon-nitrogen bonds to form amines is one of the most important chemical transformations for the... 
AMINATION | COMPLEX | ACTIVATION | HYDROGENATION | REACTIVITY | N-ALKYLATION | ALDEHYDES | METAL CATALYSIS | EFFICIENT | MULTIDISCIPLINARY SCIENCES
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2019, Volume 2019, Issue 44, pp. 7372 - 7377
Until now, the substitution of alcohols by N‐nucleophiles via TBN‐catalyzed dehydrogenation was not known. Herein, we reported a TBN catalyzed dehydrative... 
TBN | N‐alkylation | TEMPO | Substitution | Alcohols
Journal Article
SCIENCE, ISSN 0036-8075, 08/2007, Volume 317, Issue 5839, pp. 790 - 792
Given the widespread importance of amides in biochemical and chemical systems, an efficient synthesis that avoids wasteful use of stoichiometric coupling... 
ELECTRON-RICH | DEHYDROGENATION | NITRILES | CONVERSION | MULTIDISCIPLINARY SCIENCES | ESTERS | RUTHENIUM COMPLEXES | AMIDATION | LACTAMS | CATALYZED N-ALKYLATION
Journal Article
Zeitschrift für Kristallographie - New Crystal Structures, ISSN 1433-7266, 12/2018, Volume 234, Issue 1, pp. 105 - 107
O, triclinic, 1̄ (no. 2), = 10.2233(9) Å, = 10.2902(9) Å, = 24.2253(19) Å, = 86.607(7)°, = 88.529(7)°, = 62.515(9)°, = 2256.9(4) Å , = 8, ) = 0.0425, ) =... 
1848646 | AMINES | N-ALKYLATION | CRYSTALLOGRAPHY
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 09/2019, Volume 21, Issue 17, pp. 7073 - 7077
An efficient strategy for N/O-(deutero)alkylation of indoles and phenols with alkoxides/alcohols as the alkylation reagents is described. The consecutive... 
DRUG | CHEMISTRY, ORGANIC | AMINES | DEUTERIUM | DISCOVERY | CATALYZED N-ALKYLATION
Journal Article
Chemical Communications, ISSN 1359-7345, 07/2015, Volume 51, Issue 59, pp. 11907 - 11910
An efficient Lewis acid-assisted, iron-catalyzed amination of alcohols using borrowing hydrogen methodology was developed. In particular, silver fluoride was... 
(HETERO)AROMATIC AMINES | IRIDIUM | VERSATILE | BORROWING HYDROGEN | TRANSITION-METAL | COMPLEXES | N-ALKYLATION | SULFONAMIDES | CHEMISTRY, MULTIDISCIPLINARY | SELECTIVE ALKYLATION | EFFICIENT CATALYSTS
Journal Article
Organic Letters, ISSN 1523-7060, 06/2016, Volume 18, Issue 11, pp. 2580 - 2583
A strategy for the synthesis of quinazolinones via acceptorless coupling of o-aminobenzamides with methanol has been accomplished in the presence of the... 
FUNCTIONAL BIPYRIDONATE LIGAND | ALCOHOLS | OXIDATION | KETONES | METHYLATION | CATALYTIC-SYSTEM | CHEMISTRY, ORGANIC | HYDROGEN-PRODUCTION | N-ALKYLATION | IRIDIUM COMPLEX | WATER
Journal Article
Science, ISSN 0036-8075, 8/2010, Volume 329, Issue 5992, pp. 635 - 636
Alcohols are relatively common starting materials for chemical reactions, even though they are quite unreactive. For example, reactions that would substitute... 
Amines | Ruthenium | Catalysts | Hydrogen | Halides | PERSPECTIVES | Tetrahedrons | Iridium | Aldehydes | Nucleophiles | Alcohols | BORROWING HYDROGEN METHODOLOGY | SULFONAMIDES | AMINES | MULTIDISCIPLINARY SCIENCES | CATALYZED N-ALKYLATION
Journal Article
Organic Letters, ISSN 1523-7060, 03/2017, Volume 19, Issue 5, pp. 1080 - 1083
An ionic cobalt–PNP complex is developed for the efficient α-alkylation of ketones with primary alcohols for the first time. A broad range of ketone and... 
ASYMMETRIC TRANSFER HYDROGENATION | MILD REACTION CONDITIONS | SELECTIVE HYDROGENATION | C BOND FORMATION | BRANCHED PRODUCTS | PINCER COMPLEXES | CHEMISTRY, ORGANIC | N-ALKYLATION | AROMATIC-AMINES | IRIDIUM CATALYSTS | ASTERISK-LR COMPLEX
Journal Article
Organic Letters, ISSN 1523-7060, 09/2013, Volume 15, Issue 17, pp. 4600 - 4603
Copper-catalyzed cross-dehydrogenative coupling (CDC) reactions of (benzo)thiazoles with cyclic ethers were developed under mild conditions. In particular, the... 
AZOLES | AMINATION | ACTIVATION | HETEROARENES | DIRECT ARYLATION | HETEROCYCLES | CHEMISTRY, ORGANIC | N-ALKYLATION | BENZOXAZOLES | H BOND FUNCTIONALIZATION | RADICAL-ADDITION
Journal Article
Organic Letters, ISSN 1523-7060, 07/2016, Volume 18, Issue 14, pp. 3462 - 3465
Efficient alkylations of amines by alcohols catalyzed by well-defined Co­(II) complexes are described that are stabilized by a PCP ligand... 
BORROWING HYDROGEN METHODOLOGY | SECONDARY ALCOHOLS | (HETERO)AROMATIC AMINES | MILD REACTION CONDITIONS | TERTIARY-AMINES | ACCEPTORLESS DEHYDROGENATION | CHEMISTRY, ORGANIC | N-ALKYLATION | IRIDIUM COMPLEX | SELECTIVE ALKYLATION | EFFICIENT CATALYSTS
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 03/2017, Volume 53, Issue 22, pp. 3265 - 3268
A novel rhenium complex bearing a non-innocent PNP pincer ligand was prepared. This novel catalyst is active in hydrogen autotransfer reactions to form new C-C... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2016, Volume 138, Issue 48, pp. 15543 - 15546
This study represents the first example an environmentally benign, sustainable, and practical synthesis of substituted quinolines and pyrimidines using... 
BORROWING HYDROGEN METHODOLOGY | SECONDARY ALCOHOLS | ALPHA-ALKYLATION | N-ALKYLATION | BOND FORMATION | RUTHENIUM | GAMMA-AMINO-ALCOHOLS | IRIDIUM COMPLEX | CHEMISTRY, MULTIDISCIPLINARY | AROMATIC-AMINES | C-H | Pyrimidines | Usage | Analysis | Chemical bonds | Amides | Chemical properties | Chemical synthesis
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 07/2015, Volume 51, Issue 59, pp. 11907 - 11910
An efficient Lewis acid-assisted, iron-catalyzed amination of alcohols using borrowing hydrogen methodology was developed. In particular, silver fluoride was... 
Lewis acid | Silver | Additives | Fluorides | Methodology | Alcohols
Journal Article
Green Chemistry, ISSN 1463-9262, 2007, Volume 9, Issue 5, pp. 411 - 420
In 2005, the ACS Green Chemistry Institute (GCI) and the global pharmaceutical corporations developed the ACS GCI Pharmaceutical Roundtable to encourage the... 
ALCOHOLS | OXIDATION | MITSUNOBU REACTION | CATALYZED HYDROGENATION | N-ALKYLATION | ASYMMETRIC HYDROGENATION | FLUORINATION | TRIPHENYLPHOSPHINE | CHEMISTRY, MULTIDISCIPLINARY | REDUCTIVE AMINATION | AMINO-ACID-DERIVATIVES | Pharmaceutical industry | green development
Journal Article
Chem. Sci, ISSN 2041-6520, 2014, Volume 5, Issue 2, pp. 649 - 655
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 09/2011, Volume 15, Issue 5, pp. 1052 - 1062
A recent development for the efficient and environmentally friendly synthesis of aliphatic amines is the transition-metal-catalyzed redox-neutral coupling of... 
OXIDATION | CHEMISTRY, ORGANIC | N-ALKYLATION | CHEMISTRY, APPLIED | DIMETHYLSULFOXIDE | VERSATILE
Journal Article
Journal of the Serbian Chemical Society, ISSN 0352-5139, 2019, Volume 84, Issue 7, pp. 639 - 647
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel... 
piperidine | analgesics | dopaminergic | heterocycles | piperazine | N-alkylation
Journal Article
Organic Letters, ISSN 1523-7060, 08/2018, Volume 20, Issue 15, pp. 4397 - 4400
Tetrakis­(dimethylamido)­diboron and tetrahydroxydiboron are herein reported as new catalysts for the synthesis of aryl amides by catalytic condensation of... 
PALLADIUM | AMIDE-BOND | CARBON | NITRILE | CHEMISTRY, ORGANIC | N-ALKYLATION | CONDENSATION | ALPHA | TRANSAMIDATION | EFFICIENT | HYDRATION
Journal Article
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