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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 09/2002, Volume 91, Issue 5, pp. 406 - 413
ABSTRACT—Angiotensin II (Ang II)–stimulated hypertrophy of vascular smooth muscle cells is mediated by reactive oxygen species (ROS) derived from NAD(P)H... 
Reactive oxygen species | Vascular smooth muscle | Angiotensin II | Rac | NAD(P)H oxidase | NADPH-OXIDASE | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | vascular smooth muscle | PHOSPHATIDYLINOSITOL 3-KINASE | GUANOSINE TRIPHOSPHATASES | SUPEROXIDE ANION PRODUCTION | GROWTH-FACTOR RECEPTOR | angiotensin II | reactive oxygen species | ENDOTHELIAL-CELLS | REQUIRES | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | SMOOTH-MUSCLE CELLS | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | Maleimides - pharmacology | rac GTP-Binding Proteins - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Time Factors | Protein Kinase C - metabolism | src-Family Kinases - metabolism | Indoles - pharmacology | Chromones - pharmacology | NADH, NADPH Oxidoreductases - metabolism | NADH, NADPH Oxidoreductases - drug effects | Muscle, Smooth, Vascular - drug effects | Pyrazoles - pharmacology | NADPH Oxidases | Angiotensin II - pharmacology | src-Family Kinases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Pyrimidines - pharmacology | Muscle, Smooth, Vascular - cytology | Rats, Sprague-Dawley | Hydrogen Peroxide - metabolism | Animals | Androstadienes - pharmacology | Signal Transduction - drug effects | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 04/2010, Volume 106, Issue 6, pp. 1117 - 1128
RATIONAL:AMP-activated protein kinase (AMPK) is an energy sensor and ubiquitously expressed in vascular cells. Recent studies suggest that AMPK activation... 
NF-κ | AMPK | NAD(P)H oxidase | Proteasome | NF-κB | NAD(P)H Oxidase
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2006, Volume 26, Issue 12, pp. 2688 - 2695
Journal Article
by Wang, SX and Zhang, M and Liang, B and Xu, J and Xie, ZL and Liu, C and Viollet, B and Yan, DG and Zou, MH
CIRCULATION RESEARCH, ISSN 0009-7330, 04/2010, Volume 106, Issue 6, pp. 1117 - 1128
Rational: AMP-activated protein kinase (AMPK) is an energy sensor and ubiquitously expressed in vascular cells. Recent studies suggest that AMPK activation... 
proteasome | NADPH OXIDASE | CARDIAC & CARDIOVASCULAR SYSTEMS | HEAT-SHOCK-PROTEIN-90 | PHOSPHORYLATION | BETA-CELL APOPTOSIS | NECROSIS-FACTOR-ALPHA | PROTEIN-KINASE ACTIVATION | NAD(P)H oxidase | SYNTHASE | NF-kappa B | AMPK | PERIPHERAL VASCULAR DISEASE | HIGH-GLUCOSE | HEMATOLOGY | NF-KAPPA-B
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2007, Volume 27, Issue 12, pp. 2627 - 2633
OBJECTIVE—Hyperglycemia is the main determinant of long-term diabetic complications, mainly through induction of oxidative stress. NAD(P)H oxidase is a major... 
Rosiglitazone | Oxidative stress | AMPK | Diabetes | NAD(P)H oxidase | RESPIRATORY BURST | ACTIVATED PROTEIN-KINASE | RECEPTOR-GAMMA | VEIN ENDOTHELIAL-CELLS | DIABETIC-PATIENTS | SKELETAL-MUSCLE | SIGNALING PATHWAY | INSULIN-RESISTANCE | NITRIC-OXIDE | rosiglitazone | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | diabetes | oxidative stress | CORONARY-ARTERY-DISEASE | Enzyme Activators - pharmacology | Phosphorylation | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | PPAR gamma - drug effects | Humans | NADPH Oxidases - metabolism | Multienzyme Complexes - metabolism | Male | Muscle, Skeletal - metabolism | PPAR gamma - metabolism | Phosphoproteins - metabolism | AMP-Activated Protein Kinases | Transfection | RNA Interference | Protein Kinase C - metabolism | Muscle, Skeletal - drug effects | Thiazolidinediones - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Muscle, Skeletal - enzymology | Endothelial Cells - metabolism | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Rats | Multienzyme Complexes - genetics | Protein Kinase C - antagonists & inhibitors | Antioxidants - pharmacology | NADPH Oxidase 2 | Rats, Sprague-Dawley | Protein Transport | Animals | Signal Transduction - drug effects | Glucose - metabolism | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Oxidative Stress - drug effects | Endothelial Cells - enzymology | rac1 GTP-Binding Protein - metabolism | Endothelial Cells - drug effects | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2001, Volume 89, Issue 5, pp. 408 - 414
We previously reported enhanced expression of the p67 and gp91 components of NAD(P)H oxidase in angiotensin (Ang) II–induced hypertension, suggesting de novo... 
gp91 | p47 | Superoxide | Angiotensin II | NAD(P)H oxidase
Journal Article
CIRCULATION RESEARCH, ISSN 0009-7330, 12/2002, Volume 91, Issue 12, pp. 1160 - 1167
Vascular endothelial growth factor (VEGF) induces angiogenesis by stimulating endothelial cell proliferation and migration, primarily through the receptor... 
GP91PHOX | NADPH OXIDASE | CELLS | endothelial cells | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | angiogenesis | ANGIOTENSIN-II | H2O2 | NAD(P)H oxidase | INHIBITION | vascular endothelial growth factor | reactive oxygen species | DISEASE | PERIPHERAL VASCULAR DISEASE | SUPEROXIDE PRODUCTION | RECEPTORS | HEMATOLOGY | Endothelium, Vascular - cytology | Free Radical Scavengers - pharmacology | Neovascularization, Physiologic - drug effects | Vascular Endothelial Growth Factor A | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Vascular Endothelial Growth Factors | Humans | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Endothelial Growth Factors - pharmacology | Cell Movement - physiology | Intercellular Signaling Peptides and Proteins - physiology | Membrane Glycoproteins - antagonists & inhibitors | Genes, Dominant | Superoxides - metabolism | Female | Lymphokines - pharmacology | Phosphorylation - drug effects | Genes, Reporter | Endothelial Growth Factors - physiology | Oligonucleotides, Antisense - pharmacology | Lymphokines - physiology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | NADPH Oxidase 2 | Subcellular Fractions - metabolism | Cell Division - drug effects | Membrane Glycoproteins - genetics | Mice, Knockout | Cell Division - physiology | Cell Movement - drug effects | Neovascularization, Physiologic - physiology | Animals | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Intercellular Signaling Peptides and Proteins - pharmacology | Signal Transduction - physiology | Mice | rac1 GTP-Binding Protein - biosynthesis | rac1 GTP-Binding Protein - genetics | Index Medicus
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 12/2002, Volume 91, Issue 12, pp. 1160 - 1167
ABSTRACT—Vascular endothelial growth factor (VEGF) induces angiogenesis by stimulating endothelial cell proliferation and migration, primarily through the... 
Angiogenesis | Reactive oxygen species | Vascular endothelial growth factor | Endothelial cells | NAD(P)H oxidase
Journal Article
CIRCULATION, ISSN 0009-7322, 05/2005, Volume 111, Issue 18, pp. 2347 - 2355
Background - Neovascularization is potentially important for the treatment of ischemic heart and limb disease. We reported that reactive oxygen species (ROS)... 
PROGENITOR CELLS | NADPH OXIDASE | CARDIAC & CARDIOVASCULAR SYSTEMS | angiogenesis | MECHANISMS | NAD(P)H oxidase | ischemia | ARTERIOGENESIS | IN-VITRO | vascular endothelial growth factor | reactive oxygen species | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | BBZ/WOR DIABETIC-RAT | MICE | MEDIATORS | HEMATOLOGY | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Journal of Molecular Catalysis. B, Enzymatic, ISSN 1381-1177, 12/2016, Volume 134, pp. 331 - 339
Biocatalytic oxidations can offer clear advantages compared to chemically catalyzed oxidations in terms of chemo, regio and stereoselectivity as well as a... 
NADH(P)H oxidase | Biooxidation | Co-factor regeneration | Oxidoreductase | L-GLUTAMATE | CHEMISTRY, PHYSICAL | H2O-FORMING NADH OXIDASE | STREPTOCOCCUS-FAECALIS 10C1 | PEROXIDASE | REDUCTION | ALCOHOL-DEHYDROGENASE | NAD(+) REGENERATION | MOLECULAR-CLONING | WHOLE-CELL BIOCATALYST | ENZYMATIC OXIDATION
Journal Article