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nad glycohydrolase (154) 154
animals (133) 133
biochemistry & molecular biology (126) 126
humans (101) 101
cyclic adp-ribose (79) 79
nad (74) 74
adp-ribosyl cyclase (72) 72
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nad+ nucleosidase - metabolism (61) 61
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nad+ glycohydrolase (41) 41
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nad+ nucleosidase - chemistry (26) 26
antigens, differentiation - metabolism (25) 25
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pertussis toxin (23) 23
cells, cultured (22) 22
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activation (21) 21
adenosine diphosphate ribose - analogs & derivatives (20) 20
adp-ribosyltransferase (20) 20
analysis (20) 20
antigen cd38 (20) 20
cyclase activity (20) 20
n-glycosyl hydrolases - metabolism (20) 20
adp-ribosyl cyclase - metabolism (19) 19
human erythrocytes (19) 19
nad+-glycohydrolase (19) 19
poly polymerases - metabolism (19) 19
signal transduction (19) 19
substrate specificity (19) 19
base sequence (18) 18
islet-activating protein (18) 18
nad - analogs & derivatives (18) 18
nadase (18) 18
nicotinamide adenine-dinucleotide (18) 18
crystal-structure (17) 17
cyclase (17) 17
identification (17) 17
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cattle (16) 16
hl-60 cells (16) 16
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oncology (15) 15
ribosylation (15) 15
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adp-ribose (14) 14
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bacterial proteins - metabolism (14) 14
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adp ribose transferases - metabolism (13) 13
ca2+ release (13) 13
cloning, molecular (13) 13
inositol trisphosphate (13) 13
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surface (13) 13
surface antigen cd38 (13) 13
adenine-nucleotides (12) 12
adp-ribosyl cyclase 1 - metabolism (12) 12
antigens, cd - metabolism (12) 12
binding (12) 12
bordetella-pertussis (12) 12
calcium-mobilizing metabolite (12) 12
nad+ nucleosidase - antagonists & inhibitors (12) 12
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retinoic acid (12) 12
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Autophagy, ISSN 1554-8627, 02/2020, Volume 16, Issue 2, pp. 334 - 346
Autophagy selectively targets invading bacteria to defend cells, whereas bacterial pathogens counteract autophagy to survive in cells. The initiation of... 
NAD-glycohydrolase | PIK3C3 | RAB GTPase | Autophagy | group A Streptococcus
Journal Article
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 8, pp. 2107 - 2150
Starting from 4-amino-8-quinoline carboxamide lead and scaffold hopping to the chemically more tractable quinazoline, a systematic exploration of the... 
NAD | CD38 inhibitor | Nicotinamide adenine dinucleotide | CD38 | NAD glycohydrolase | CELLS | DESIGN | CHEMISTRY, MEDICINAL | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | IDENTIFICATION | DISCOVERY | BIOLOGICAL EVALUATION | TOOL | Medicine, Experimental | Quinoline | Medical research | Analysis
Journal Article
Cellular Microbiology, ISSN 1462-5814, 09/2015, Volume 17, Issue 9, pp. 1376 - 1390
Streptococcus pyogenes uses the cytolysin streptolysin O (SLO) to translocate an enzyme, the S.pyogenesNAD(+) glycohydrolase (SPN), into the host cell cytosol.... 
APOPTOSIS | POLY(ADP-RIBOSE) POLYMERASE PARP | ACTIVATION | GROUP-A STREPTOCOCCUS | STREPTOLYSIN-O | NAD(+) GLYCOHYDROLASE | MICROBIOLOGY | DEATH | CYTOLYSIN-MEDIATED TRANSLOCATION | PORE-FORMING TOXINS | HELICOBACTER-PYLORI | CELL BIOLOGY | Enzymes | Rodents | Bacteriology
Journal Article
Journal Article
TOXINS, ISSN 2072-6651, 08/2019, Volume 11, Issue 8, p. 437
Pertussis toxin (PT) is a multimeric complex of six proteins. The PTS1 subunit is an ADP-ribosyltransferase that inactivates the alpha subunit of... 
translocation | CHEMICAL CHAPERONES | retrograde transport | S1 SUBUNIT | NAD GLYCOHYDROLASE | ERAD | chaperone | ADENINE-NUCLEOTIDES | ISLET-ACTIVATING PROTEIN | ADP-RIBOSYLATION | endocytosis | AB toxin | ENDOPLASMIC-RETICULUM | TOXICOLOGY | BORDETELLA-PERTUSSIS | endoplasmic reticulum | CHOLERA-TOXIN
Journal Article
Journal Article