X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
nadh, nadph oxidoreductases - antagonists & inhibitors (1094) 1094
animals (1083) 1083
nadh, nadph oxidoreductases - metabolism (819) 819
humans (583) 583
biochemistry & molecular biology (464) 464
rats (402) 402
kinetics (355) 355
enzyme inhibitors - pharmacology (351) 351
index medicus (331) 331
nadph oxidases (293) 293
male (287) 287
oxidation-reduction (283) 283
mice (224) 224
multienzyme complexes - antagonists & inhibitors (209) 209
in vitro techniques (204) 204
superoxides - metabolism (198) 198
cattle (193) 193
oxidative stress (177) 177
reactive oxygen species - metabolism (172) 172
nadh, nadph oxidoreductases - genetics (161) 161
multienzyme complexes - metabolism (159) 159
cells, cultured (148) 148
structure-activity relationship (146) 146
electron transport complex i (145) 145
pharmacology & pharmacy (140) 140
nadph oxidase 1 (132) 132
nad - metabolism (129) 129
female (126) 126
cell biology (125) 125
nadph oxidase (124) 124
nadh oxidase (123) 123
biophysics (122) 122
chemistry, medicinal (122) 122
binding sites (107) 107
dose-response relationship, drug (106) 106
enzyme inhibitors - chemistry (102) 102
neutrophils - enzymology (100) 100
onium compounds - pharmacology (100) 100
superoxide (99) 99
mitochondria - enzymology (98) 98
research article (98) 98
activation (97) 97
electron transport (97) 97
nadh, nadph oxidoreductases - chemistry (97) 97
neutrophils - drug effects (97) 97
enzymes (96) 96
mitochondria (95) 95
electron transport - drug effects (93) 93
rotenone - pharmacology (93) 93
enzyme activation (90) 90
hydrogen-ion concentration (88) 88
mitochondria - drug effects (88) 88
mitochondria - metabolism (87) 87
trypanothione reductase (85) 85
cell membrane - enzymology (83) 83
cell line (80) 80
oxygen consumption - drug effects (80) 80
expression (79) 79
mitochondria, heart - enzymology (79) 79
inhibition (77) 77
nadph oxidases - metabolism (77) 77
oxidases (76) 76
time factors (76) 76
molecular sequence data (75) 75
nadp - metabolism (75) 75
tetradecanoylphorbol acetate - pharmacology (75) 75
neutrophils - metabolism (74) 74
purification (74) 74
nadh, nadph oxidoreductases - blood (72) 72
reactive oxygen species (72) 72
hydrogen peroxide - metabolism (71) 71
cells (70) 70
enzyme activation - drug effects (70) 70
substrate specificity (69) 69
amino acid sequence (68) 68
free radicals (68) 68
liver - enzymology (68) 68
apoptosis (67) 67
metabolism (67) 67
molecular structure (67) 67
phosphorylation (67) 67
oxidoreductases - antagonists & inhibitors (66) 66
physiological aspects (66) 66
rats, sprague-dawley (66) 66
models, molecular (65) 65
rats, wistar (65) 65
trypanosoma-cruzi (65) 65
nadh dehydrogenase (64) 64
drug design (63) 63
research (63) 63
trypanosoma cruzi - enzymology (63) 63
nadh, nadph oxidoreductases - isolation & purification (62) 62
glutathione-reductase (61) 61
analysis (60) 60
quinone reductases - antagonists & inhibitors (60) 60
enzyme inhibitors (58) 58
inhibitors (58) 58
molecular weight (58) 58
peripheral vascular disease (58) 58
proteins (58) 58
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1683) 1683
Japanese (23) 23
Russian (21) 21
German (16) 16
French (7) 7
Chinese (3) 3
Italian (3) 3
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of the American Society of Nephrology, ISSN 1046-6673, 06/2014, Volume 25, Issue 6, pp. 1237 - 1254
Journal Article
Diabetologia, ISSN 0012-186X, 05/2017, Volume 60, Issue 5, pp. 927 - 937
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2012, Volume 53, Issue 2, pp. 289 - 296
Reactive oxygen species (ROS) play a key role in chronic liver injury and fibrosis. Homologs of NADPH oxidases (NOXs) are major sources of ROS, but the exact... 
NADPH oxidase 4 | Liver fibrosis | Stellate cell activation | Hepatocyte apoptosis | NADPH OXIDASE | ACTIVATION | TGF-BETA | ISOFORMS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | FIBROGENESIS | MECHANISMS | HEPATIC STELLATE CELLS | ENDOCRINOLOGY & METABOLISM | NAD(P)H OXIDASES | STRESS | Liver - pathology | Pyrazoles - therapeutic use | Liver - enzymology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Bile Ducts - metabolism | Humans | NADPH Oxidases - metabolism | Hepatitis, Autoimmune - drug therapy | Hepatocytes - pathology | Smad3 Protein - metabolism | Liver Cirrhosis - enzymology | Hepatic Stellate Cells - cytology | Hepatitis, Autoimmune - pathology | Fas Ligand Protein - pharmacology | Ligation | Liver - drug effects | Gene Deletion | NADPH Oxidases - genetics | NADH, NADPH Oxidoreductases - metabolism | Hepatocytes - drug effects | Hepatic Stellate Cells - drug effects | Pyrazoles - pharmacology | Pyridines - therapeutic use | Liver Cirrhosis - drug therapy | NADH, NADPH Oxidoreductases - genetics | Bile Ducts - drug effects | NADPH Oxidases - antagonists & inhibitors | Rats | Bile Ducts - surgery | NADPH Oxidase 4 | NADPH Oxidase 1 | Reactive Oxygen Species - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Liver Cirrhosis - pathology | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Pyridines - pharmacology | Dactinomycin - pharmacology | Transforming Growth Factor beta - metabolism | Hepatitis, Autoimmune - enzymology | Hepatocytes - enzymology | Oxidases | Phosphates | Niacinamide | Purines | Liver diseases | Analysis | Liver | Fibrosis | Bone morphogenetic proteins | Transforming growth factors | Muscle proteins | Apoptosis | stellate cell activation | liver fibrosis | hepatocyte apoptosis | nicotinamide adenine dinucleotide phosphate reduced oxidase 4
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0129743
Reactive oxygen species (ROS) produced by nicotinamide adenine dinucleotide phosphate oxidase (NOX) play a key role in liver injury and fibrosis. Previous... 
TRANSFORMATION | NADPH OXIDASE | HEPATOCYTE APOPTOSIS | OXIDATIVE STRESS | SIGNALING PATHWAYS | HEDGEHOG PATHWAY | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | NAD(P)H OXIDASES | PROLIFERATION | EXPRESSION | NADPH Oxidases - chemistry | Reactive Oxygen Species - metabolism | Humans | NADPH Oxidases - metabolism | Hedgehog Proteins - metabolism | Hepatic Stellate Cells - metabolism | Platelet-Derived Growth Factor - genetics | Myofibroblasts - metabolism | Carbon Tetrachloride Poisoning - metabolism | Hedgehog Proteins - genetics | Hepatitis - genetics | Hepatitis - metabolism | Liver Cirrhosis - metabolism | NADPH Oxidases - genetics | NADH, NADPH Oxidoreductases - metabolism | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | Myofibroblasts - pathology | NADH, NADPH Oxidoreductases - genetics | Signal Transduction | NADPH Oxidases - antagonists & inhibitors | Hepatitis - pathology | NADPH Oxidase 4 | Pyrazoles - metabolism | Carbon Tetrachloride Poisoning - pathology | NADPH Oxidase 1 | Mice, Knockout | Platelet-Derived Growth Factor - metabolism | Animals | Pyridines - metabolism | Liver Cirrhosis - pathology | Carbon Tetrachloride Poisoning - genetics | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Niacinamide | Platelet-derived growth factor | Carbon tetrachloride | Fibrosis | Inflammation | Comparative analysis | Liver cirrhosis | Phosphates | Oxidative stress | Pathogenesis | Liver | Genes | Lipid peroxidation | Activation | NAD(P)H oxidase | Lipopolysaccharides | Veterinarians | Hepatitis | Cell activation | NOX4 protein | Rodents | Cell cycle | Peroxidation | Medical research | Stellate cells | Enzymes | NADPH-diaphorase | Adenine | CCL4 protein | Medicine | Cirrhosis | Signaling | Injury prevention | Inhibitors | Hedgehog protein | Nicotinamide adenine dinucleotide | Nicotinamide | Laboratory animals | Plastics | Apoptosis | Bile
Journal Article
Stroke, ISSN 0039-2499, 2007, Volume 38, Issue 11, pp. 3000 - 3006
Background and Purpose - Cerebral ischemia/reperfusion is associated with reactive oxygen species (ROS) generation, and NADPH oxidases are important sources of... 
Oxidative stress | Ischemia/reperfusion | RhoA | Statins | Endothelium | REDUCTASE INHIBITORS | endothelium | FOCAL CEREBRAL-ISCHEMIA | NEURONAL DAMAGE | RAT MODEL | CLINICAL NEUROLOGY | FREE-RADICALS | IN-VITRO | statins | ENDOTHELIAL-CELLS | ischemia/ reperfusion | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | SUPEROXIDE-DISMUTASE | oxidative stress | Infarction, Middle Cerebral Artery - physiopathology | Cell Hypoxia - physiology | Reactive Oxygen Species - metabolism | Blood-Brain Barrier - physiopathology | Male | Protein Transport - physiology | Protein Transport - drug effects | Stroke - physiopathology | rho-Associated Kinases - antagonists & inhibitors | Brain Edema - enzymology | MAP Kinase Signaling System - genetics | rho-Associated Kinases - metabolism | NADH, NADPH Oxidoreductases - metabolism | Disease Models, Animal | NADH, NADPH Oxidoreductases - genetics | Brain Edema - etiology | Endothelial Cells - metabolism | Reperfusion Injury - enzymology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Enzyme Activation - drug effects | NADPH Oxidase 1 | Mice, Knockout | Stroke - enzymology | Animals | Blood-Brain Barrier - enzymology | MAP Kinase Signaling System - drug effects | Brain Edema - physiopathology | Reperfusion Injury - physiopathology | rac1 GTP-Binding Protein - antagonists & inhibitors | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Infarction, Middle Cerebral Artery - enzymology | Enzyme Activation - physiology | Sus scrofa | rac1 GTP-Binding Protein - metabolism
Journal Article
Journal Article
Journal Article
Clinical Science, ISSN 0143-5221, 02/2013, Volume 124, Issue 3, pp. 191 - 202
Nox (NADPH oxidase)-derived ROS (reactive oxygen species) have been implicated in the development of diabetic nephropathy. Of the Nox isoforms in the kidney,... 
Oxidative stress | Diabetes | NADPH oxidase | NOX inhibitor | Kidney | db/db mouse | KIDNEY-DISEASE | MEDICINE, RESEARCH & EXPERIMENTAL | DB/DB MICE | MECHANISMS | NEPHROPATHY | FAMILY | kidney | INDUCED OXIDATIVE STRESS | NOX4 | COMPLICATIONS | HYPERTENSION | diabetes | oxidative stress | NADPH OXIDASE INHIBITOR | Gene Expression Regulation, Enzymologic - drug effects | Superoxide Dismutase - genetics | Kidney - pathology | Diabetic Nephropathies - etiology | NADPH Oxidases - metabolism | Body Weight - drug effects | Male | Kidney - metabolism | Diabetic Nephropathies - physiopathology | NADPH Oxidases - genetics | Thiobarbituric Acid Reactive Substances - analysis | Blood Pressure - drug effects | Albuminuria - urine | NADH, NADPH Oxidoreductases - metabolism | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Type 2 - complications | Superoxide Dismutase - metabolism | Disease Models, Animal | Pyrazoles - pharmacology | NADH, NADPH Oxidoreductases - genetics | Kidney - drug effects | Blood Glucose - analysis | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Diabetes Mellitus, Type 2 - urine | NADPH Oxidase 4 | Albuminuria - prevention & control | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | NADPH Oxidase 1 | Diabetes Mellitus, Type 2 - blood | Animals | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Superoxide Dismutase-1 | Vascular Cell Adhesion Molecule-1 - metabolism | Transforming Growth Factor beta - metabolism | Pyridones - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 05/2012, Volume 16, Issue 10, pp. 133 - 1045
Aim: Oxidative stress has long been considered as a major contributing factor in the pathogenesis of Parkinson's disease. However, molecular sources for... 
Original Research Communications | CROSS-TALK | 6-HYDROXYDOPAMINE NEUROTOXICITY | CATALYTIC SUBUNIT | SUPEROXIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | SMOOTH-MUSCLE-CELLS | NAD(P)H OXIDASE-1 | COLON EPITHELIAL-CELLS | SUBSTANTIA-NIGRA | UP-REGULATION | NOX1 | Reactive Oxygen Species - metabolism | Oxidative Stress | Dopaminergic Neurons - pathology | Humans | Corpus Striatum - metabolism | Cell Nucleus - metabolism | Oxidopamine - pharmacology | Parkinson Disease - metabolism | Cell Death - drug effects | NADH, NADPH Oxidoreductases - metabolism | Cell Line | NADH, NADPH Oxidoreductases - genetics | Gene Expression | Parkinson Disease - pathology | Gene Silencing | Rats | Parkinson Disease - genetics | NADPH Oxidase 1 | Protein Transport | Dopaminergic Neurons - enzymology | Animals | rac1 GTP-Binding Protein - antagonists & inhibitors | NADH, NADPH Oxidoreductases - antagonists & inhibitors | DNA Damage | rac1 GTP-Binding Protein - metabolism | Oxidative stress | Parkinson's disease | NADP (Coenzyme) | Causes of | Development and progression | Research | Chemical properties | Dopaminergic mechanisms | Enzyme activation | Reactive oxygen species | Dopamine | Neurodegenerative diseases | DNA damage | Substantia nigra | 6-Hydroxydopamine | Rac1 protein | NAD(P)H oxidase | Antioxidants | Neurodegeneration | Neostriatum | Movement disorders
Journal Article