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1. Full Text Novel mechanism of activation of NADPH oxidase 5: Calcium sensitization via phosphorylation
by Jagnandan, Davin and Church, Jarrod E and Banfi, Botond and Stuehr, Dennis J and Marrero, Mario B and Fulton, David J. R
The Journal of biological chemistry, ISSN 0021-9258, 03/2007, Volume 282, Issue 9, pp. 6494 - 6507
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Endoplasmic Reticulum - enzymology | Phosphorylation | Reactive Oxygen Species - metabolism | Tetradecanoylphorbol Acetate - pharmacology | Membrane Proteins - genetics | Humans | NADPH Oxidases - metabolism | Cercopithecus aethiops | Calcium - analysis | NADPH Oxidase 5 | Animals | Transfection | NADPH Oxidases - genetics | Membrane Proteins - metabolism | Enzyme Activation | COS Cells | Amino Acid Substitution | Index Medicus
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2. Full Text Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 Is Mediated via Calcium/Calmodulin-Dependent, Rac-1–Independent Pathways in Human Endothelial Cells
by Montezano, Augusto C and Burger, Dylan and Paravicini, Tamara M and Chignalia, Andreia Z and Yusuf, Hiba and Almasri, Mahmoud and He, Ying and Callera, Glaucia E and He, Gang and Krause, Karl-Heinz and Lambeth, David and Quinn, Mark T and Touyz, Rhian M
Circulation research, ISSN 0009-7330, 04/2010, Volume 106, Issue 8, pp. 1363 - 1373
ERK1/2 | Reactive oxygen species | Vasoactive peptides | Vascular cells | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Vertebrates: cardiovascular system | Phosphorylation | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | RNA, Messenger - metabolism | Pyrones - pharmacology | Quinolines - pharmacology | Diltiazem - pharmacology | RNA Interference | Time Factors | Superoxides - metabolism | NADPH Oxidases - genetics | Membrane Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Calmodulin - metabolism | Angiotensin II - metabolism | Endothelin-1 - metabolism | Membrane Proteins - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | NADPH Oxidase 5 | Calcium Channel Blockers - pharmacology | Gene Expression Regulation, Enzymologic | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | rac1 GTP-Binding Protein - antagonists & inhibitors | Enzyme Activation | Proliferating Cell Nuclear Antigen - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Calmodulin - antagonists & inhibitors | Endothelial Cells - enzymology | Inflammation - enzymology | rac1 GTP-Binding Protein - metabolism | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | vascular cells | vasoactive peptides | ERK1
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3. Full Text Mechanism of Ca2+ Activation of the NADPH Oxidase 5 (NOX5)
by Botond Bánfi and Fabiana Tirone and Isabelle Durussel and Judit Knisz and Patryk Moskwa and Gergely Zoltán Molnár and Karl-Heinz Krause and Jos A. Cox
The Journal of biological chemistry, ISSN 0021-9258, 04/2004, Volume 279, Issue 18, pp. 18583 - 18591
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Calcium - pharmacology | Humans | NADPH Oxidases - metabolism | NADPH Oxidase 5 | Enzyme Activation - drug effects | Cell-Free System | Superoxides - metabolism | Melitten - pharmacology | Protein Conformation | Membrane Proteins - metabolism | Kinetics | Melitten - metabolism | Binding Sites | Index Medicus
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4. Full Text Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels
by Pandey, Deepesh and Patel, Anand and Patel, Vijay and Chen, Feng and Qian, Jin and Wang, Yusi and Barman, Scott A and Venema, Richard C and Stepp, David W and Daniel Rudic, R and Fulton, David J. R
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 05/2012, Volume 302, Issue 10, pp. H1919 - H1928
Nox5 splice variants | Reactive oxygen species | Extracellular signalregulated kinase | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Endothelium, Vascular - cytology | Cell Proliferation | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | Membrane Proteins - genetics | Blood Vessels - metabolism | Humans | Cells, Cultured | NADPH Oxidases - metabolism | NADPH Oxidase 5 | Muscle, Smooth, Vascular - cytology | RNA, Messenger - metabolism | Blood Vessels - cytology | Endothelium, Vascular - metabolism | Isoenzymes - metabolism | NADPH Oxidases - genetics | Signal Transduction - physiology | Membrane Proteins - metabolism | Blood vessels | Research | Vascular smooth muscle | Extracellular signal-regulated kinases | EF hand proteins | Proteins | Cellular biology | Smooth muscle | Ribonucleic acid--RNA | Gene expression | Endothelium | Index Medicus | Vascular Biology and Microcirculation | extracellular signal-regulated kinase | reactive oxygen species
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5. Full Text Endothelial NADPH oxidases: which NOX to target in vascular disease?
by Drummond, Grant R and Sobey, Christopher G
Trends in endocrinology and metabolism, ISSN 1043-2760, 2014, Volume 25, Issue 9, pp. 452 - 463
Endocrinology & Metabolism | hyperlipidemia | NADPH oxidases | vascular disease | selective NOX1/2 inhibitors | inflammation | reactive oxygen species | hypertension | diabetes | endothelial dysfunction | Hypertension | Vascular disease | Selective NOX1/2 inhibitors | Reactive oxygen species | Hyperlipidemia | Endothelial dysfunction | Inflammation | Diabetes | Life Sciences & Biomedicine | Science & Technology | NADPH Oxidases - chemistry | Membrane Glycoproteins - metabolism | Humans | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Endothelium, Vascular - enzymology | Molecular Targeted Therapy | Membrane Glycoproteins - antagonists & inhibitors | NADPH Oxidases - genetics | Membrane Proteins - metabolism | Vascular Diseases - drug therapy | Membrane Proteins - genetics | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Mice, Transgenic | NADPH Oxidase 5 | NADPH Oxidase 4 | Vascular Diseases - enzymology | Enzyme Inhibitors - therapeutic use | NADPH Oxidase 2 | NADPH Oxidase 1 | Cardiovascular Agents - pharmacology | Membrane Glycoproteins - genetics | Mice, Knockout | Cardiovascular Agents - therapeutic use | Animals | Membrane Proteins - antagonists & inhibitors | Models, Biological | Oxidases | Blood circulation disorders | Superoxide | Peroxides | Endothelium | Index Medicus
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6. Full Text Implications of NADPH oxidase 5 in vascular diseases
by Marqués, Javier and Cortés, Adriana and Pejenaute, Álvaro and Zalba, Guillermo
The international journal of biochemistry & cell biology, ISSN 1357-2725, 11/2020, Volume 128, pp. 105851 - 105851
Endothelial dysfunction | NADPH oxidase 5 | Oxidative stress | Inflammation | Vascular diseases | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Hypertension | Oxidases | Analysis | Genomics | Atherosclerosis | Endothelium | Index Medicus
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7. Full Text NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27Kip1 expression in malignant melanoma and other human tumors
by Antony, Smitha and Jiang, Guojian and Wu, Yongzhong and Meitzler, Jennifer L and Makhlouf, Hala R and Haines, Diana C and Butcher, Donna and Hoon, Dave S and Ji, Jiuping and Zhang, Yiping and Juhasz, Agnes and Lu, Jiamo and Liu, Han and Dahan, Iris and Konate, Mariam and Roy, Krishnendu K and Doroshow, James H
Molecular carcinogenesis, ISSN 0899-1987, 12/2017, Volume 56, Issue 12, pp. 2643 - 2662
cell growth | reactive oxygen species (ROS) | tumor microarray (TMA) | DNA damage | NADPH oxidase | Akt/GSK3 signaling | Cell proliferation | Phosphorylation | Oxygen | Oxidase | Melanoma | AKT protein | Lymphoma | NAD(P)H oxidase | Skin cancer | Signal transduction | Signaling | Hypoxia-inducible factor 1a | Cell growth | Pathways | Cascades | Cyclin-dependent kinase inhibitor p27 | Prostate cancer | Prostate | Tumors | Cancer | Index Medicus | Akt | GSK3 signaling
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8. Full Text 5‐Hydroxytryptamine (5‐HT)‐exacerbated DSS‐induced colitis is associated with elevated NADPH oxidase expression in the colon
by Dong, Shizhen and Chen, Menglu and Dai, Faliang and Xuan, Qingxia and Chen, Pan and Feng, Dandan and Gao, Lei and Zhu, Chendi and Chang, Yongchao and Chu, Fong‐Fong and Gao, Qiang
Journal of cellular biochemistry, ISSN 0730-2312, 06/2019, Volume 120, Issue 6, pp. 9230 - 9242
Nox4 | 5‐hydroxytryptamine | colitis | NADPH oxidases | Nox2 | dextran sulfate sodium | 5-hydroxytryptamine | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Oxidases | Immunohistochemistry | Dextran | Colon cancer | RNA | Analysis | Genes | Genetic research | Colitis | Sulfates | Gene expression | Epithelial cells | Colorectal cancer | mRNA | Leukocytes | Macrophages | NAD(P)H oxidase | Proteins | NOX4 gene | NOX4 protein | CYBB protein | Dextran sulfate | Peroxidase | Colon | Erosion | Ribonucleic acid--RNA | Epithelium | Inflammatory bowel disease | Polymerase chain reaction | White blood cells | Sodium | Protein expression | Mice | Infiltration | Cancer | Index Medicus
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9. Full Text Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation
by Qian, Jin and Chen, Feng and Kovalenkov, Yevgeniy and Pandey, Deepesh and Moseley, M. Arthur and Foster, Matthew W and Black, Stephen M and Venema, Richard C and Stepp, David W and Fulton, David J.R
Free radical biology & medicine, ISSN 0891-5849, 05/2012, Volume 52, Issue 9, pp. 1806 - 1819
Reactive oxygen species | Free radicals | Nox5 | Nitric oxide | NADPH oxidase | S-nitrosylation | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Line | Phosphorylation | Reactive Oxygen Species - metabolism | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | Cercopithecus aethiops | Nitric Oxide - physiology | NADPH Oxidase 5 | Blotting, Western | Animals | Nitroso Compounds - metabolism | Mass Spectrometry | Membrane Proteins - metabolism | Nitric Oxide Donors - pharmacology | COS Cells | Index Medicus | Reactive Oxygen Species
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