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Trends in endocrinology and metabolism, ISSN 1043-2760, 09/2014, Volume 25, Issue 9, pp. 452 - 463
Highlights • Endothelial cells express four NADPH oxidase isoforms: NOX1, 2, 4, and 5. • NOX1, 2, and 5 make superoxide and cause endothelial dysfunction and vascular disease... 
Endocrinology & Metabolism | hyperlipidemia | NADPH oxidases | vascular disease | selective NOX1/2 inhibitors | inflammation | reactive oxygen species | hypertension | diabetes | endothelial dysfunction | Hypertension | Vascular disease | Selective NOX1/2 inhibitors | Reactive oxygen species | Hyperlipidemia | Endothelial dysfunction | Inflammation | Diabetes | Life Sciences & Biomedicine | Science & Technology | NADPH Oxidases - chemistry | Membrane Glycoproteins - metabolism | Humans | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Endothelium, Vascular - enzymology | Molecular Targeted Therapy | Membrane Glycoproteins - antagonists & inhibitors | NADPH Oxidases - genetics | Membrane Proteins - metabolism | Vascular Diseases - drug therapy | Membrane Proteins - genetics | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Mice, Transgenic | NADPH Oxidase 5 | NADPH Oxidase 4 | Vascular Diseases - enzymology | Enzyme Inhibitors - therapeutic use | NADPH Oxidase 2 | NADPH Oxidase 1 | Cardiovascular Agents - pharmacology | Membrane Glycoproteins - genetics | Mice, Knockout | Cardiovascular Agents - therapeutic use | Animals | Membrane Proteins - antagonists & inhibitors | Models, Biological | Oxidases | Blood circulation disorders | Superoxide | Peroxides | Endothelium | Index Medicus
Journal Article
Journal Article
PLoS pathogens, ISSN 1553-7374, 02/2011, Volume 7, Issue 2, pp. e1001271 - e1001271
...), Nox2-containing NADPH oxidase, is a novel pharmacological target against the lung inflammation caused by influenza A viruses. Male WT (C57BL/6) and Nox2(-/y... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Oxidoreductases - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Orthomyxoviridae Infections - complications | NADPH Oxidases - metabolism | Pneumonia - pathology | Pneumonia - prevention & control | Male | Oxidoreductases - physiology | Lung - enzymology | Orthomyxoviridae Infections - genetics | Membrane Glycoproteins - physiology | Membrane Glycoproteins - antagonists & inhibitors | Influenza A virus - pathogenicity | NADPH Oxidases - genetics | Bronchoalveolar Lavage Fluid - cytology | Lung - metabolism | Pneumonia - genetics | Influenza A virus - physiology | Lung - pathology | Pneumonia - etiology | Bronchoalveolar Lavage Fluid - virology | Macrophages - pathology | Oxidoreductases - metabolism | Orthomyxoviridae Infections - metabolism | Oxidoreductases - genetics | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Orthomyxoviridae Infections - pathology | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Enzyme Activation - drug effects | Enzyme Inhibitors - therapeutic use | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Animals | Macrophages - drug effects | Mice | Enzyme Activation - physiology | NADPH Oxidases - physiology | Lung - immunology | Oxidases | Influenza viruses | Lung diseases | Physiological aspects | Research | Health aspects | Risk factors | Proteins | Pandemics | Lungs | Cytokines | Rodents | Index Medicus
Journal Article