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Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9973, pp. 1075 - 1086
Summary Background There is a high medical need for an interferon-free, all-oral, short-duration therapy for hepatitis C virus (HCV) that is highly effective... 
Internal Medicine | SUSTAINED VIROLOGICAL RESPONSE | MEDICINE, GENERAL & INTERNAL | PLUS RIBAVIRIN | HCV NS5A INHIBITOR | SOFOSBUVIR | TREATMENT-EXPERIENCED PATIENTS | DISEASE BURDEN | DOUBLE-BLIND | SIMEPREVIR | INTERFERON-ALPHA 2A | TREATMENT-NAIVE PATIENTS | Humans | Middle Aged | Hepacivirus - genetics | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Male | RNA, Viral - blood | Interferons - therapeutic use | Hepatitis C, Chronic - complications | Polyethylene Glycols - therapeutic use | Viral Load | Young Adult | Ribavirin - administration & dosage | Treatment Failure | Aged, 80 and over | Adult | Female | Drug Therapy, Combination | Liver Cirrhosis - etiology | Drug Administration Schedule | Quinoxalines - administration & dosage | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Adolescent | Aged | Medical colleges | Protease inhibitors | Proteases | Clinical trials | Product development | Biological response modifiers | Hepatitis C virus | Health aspects | Liver cirrhosis | Ribavirin | Comparative studies | Hepatitis | Genotype & phenotype | Interferon | Drug therapy | Index Medicus | Abridged Index Medicus | Life Sciences | Infectious Medicine | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Infektionsmedicin
Journal Article
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 01/2011, Volume 154, Issue 2, pp. 103 - 103
Background: Insulin replacement in diabetes often requires prandial intervention to reach hemoglobin A(1c) (HbA(1c)) targets. Objective: To test whether... 
NPH INSULIN | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | ORAL-THERAPY | ADD-ON | GLUCOSE-LOWERING DRUGS | COMBINATION THERAPY | PARALLEL-GROUP | NAIVE PEOPLE | OPEN-LABEL | TO-TARGET TRIAL | Metformin - therapeutic use | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Body Weight - drug effects | Male | Thiazolidinediones - administration & dosage | Peptides - administration & dosage | Thiazolidinediones - therapeutic use | Hypoglycemic Agents - administration & dosage | Injections, Subcutaneous | Sensitivity and Specificity | Venoms - administration & dosage | Female | Insulin - analogs & derivatives | Metformin - administration & dosage | Drug Therapy, Combination | Hypoglycemic Agents - therapeutic use | Insulin, Long-Acting | Double-Blind Method | Drug Administration Schedule | Venoms - adverse effects | Insulin - administration & dosage | Diabetes Mellitus, Type 2 - blood | Insulin Glargine | Venoms - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - therapeutic use | Peptides - adverse effects | Peptides - therapeutic use | Type 2 diabetes | Glycosylated hemoglobin | Physiological aspects | Research | Diagnosis | Drug therapy | Injections | Side effects | Clinical trials | Diabetes | Hypoglycemia | Insulin | Weight | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2011, Volume 29, Issue 21, pp. 2866 - 2874
Purpose The results of the Iressa Pan-Asia Study (IPASS), which compared gefitinib and carboplatin/paclitaxel in previously untreated never-smokers and light... 
TRIAL | CHEMOTHERAPY-NAIVE PATIENTS | FACTOR-RECEPTOR GENE | PLACEBO | ONCOLOGY-GROUP | ONCOLOGY | TYROSINE KINASE | SENSITIVITY | EGFR MUTATIONS | MOLECULAR PREDICTORS | PREVIOUSLY TREATED PATIENTS | Immunohistochemistry | Lung Neoplasms - drug therapy | Predictive Value of Tests | Adenocarcinoma - pathology | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Time Factors | Gefitinib | Odds Ratio | Paclitaxel - administration & dosage | Adenocarcinoma - chemistry | Precision Medicine | ErbB Receptors - antagonists & inhibitors | Lung Neoplasms - chemistry | Risk Assessment | Risk Factors | Carboplatin - administration & dosage | In Situ Hybridization, Fluorescence | Logistic Models | Survival Rate | Adenocarcinoma - drug therapy | Biomarkers, Tumor - genetics | Mutation | Carcinoma, Non-Small-Cell Lung - chemistry | Adenocarcinoma of Lung | ErbB Receptors - genetics | Lung Neoplasms - pathology | Patient Selection | Female | Adenocarcinoma - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Biomarkers, Tumor - analysis | Carcinoma, Non-Small-Cell Lung - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Gene Dosage | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Asia | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | ErbB Receptors - analysis | Adenocarcinoma - mortality | Index Medicus
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 8, pp. 714 - 725
Journal Article