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Cell, ISSN 0092-8674, 09/2016, Volume 167, Issue 1, pp. 187 - 202.e17
Journal Article
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 07/2010, Volume 54, Issue 3, pp. 236 - 240
Objectives: Innate immunity genes polymorphisms are known to be involved in the multifactorial susceptibility to HIV-1 infection. Recently it has been... 
HIV-1 | NALP3/NLRP3/CIAS1 | genetics | innate immunity | inflammasome | NALP1/NLRP1 | IL-1beta | polymorphisms | IMMUNITY | INFECTIOUS DISEASES | CCL3L1 | IMMUNOLOGY | NALP3 INFLAMMASOME | DISEASE
Journal Article
by Li, Q and Tian, Y and Wang, ZF and Liu, SB and Mi, WL and Ma, HJ and Wu, GC and Wang, J and Yu, J and Wang, YQ
NEUROSCIENCE, ISSN 0306-4522, 12/2013, Volume 254, pp. 230 - 240
Neuroinflammation plays an important role in nerve-injury-induced neuropathic pain, but the explicit molecular mechanisms of neuroinflammation in neuropathic... 
CYTOKINES | MINOCYCLINE | ACTIVATION | RATS | LIPID MEDIATORS | NERVE INJURY | NEUROSCIENCES | caspase | neuropathic pain | MOLECULAR PLATFORM | NALP1 inflammasome | TRAUMATIC BRAIN-INJURY | LIPOXIN | aspirin-triggered-15-epi-lipoxin A4 | IL-1-BETA | interleukin
Journal Article
Immunity, ISSN 1074-7613, 12/2012, Volume 37, Issue 6, pp. 1009 - 1023
Cytopenias are key prognostic indicators of life-threatening infection, contributing to immunosuppression and mortality. Here we define a role for... 
NALP1 | LETHAL TOXIN | IN-VIVO | DISEASE | BINDING-PROTEIN | DEATH | INFECTION | IMMUNOLOGY | TIR DOMAIN | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | CASPASE-1 ACTIVATION | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | Dermatitis - immunology | Pancytopenia - immunology | Caspase 1 - metabolism | Interferon-gamma - metabolism | Hematopoiesis - drug effects | Inflammation - metabolism | T-Lymphocytes - metabolism | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Hematopoietic Stem Cells - virology | Hematopoietic Stem Cells - drug effects | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Pancytopenia - metabolism | Hematopoiesis - immunology | Animals | CARD Signaling Adaptor Proteins | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | T-Lymphocytes - immunology | Fluorouracil - pharmacology | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Interleukin-18 - metabolism | Apoptosis | Dermatitis - metabolism | Chemotherapy | Research | Health aspects | Oncology, Experimental | Immunotherapy | Cancer | Proteins | Medical research | Disease | Councils | Bone marrow | Infections | Grants | Kinases | pyroptosis | inflammasome | IL-18 | progenitor cells | NLRP1 | cytopenia | IL-1β | sepsis
Journal Article
Cell Metabolism, ISSN 1550-4131, 2011, Volume 13, Issue 5, pp. 540 - 549
We show that mice with a targeted deficiency in the gene encoding the lipogenic transcription factor SREBP-1a are resistant to endotoxic shock and systemic... 
GAMMA | CECAL LIGATION | GENE | CHOLESTEROL | ROLES | INFLAMMASOME | ENDOCRINOLOGY & METABOLISM | RESISTANCE | TYPHIMURIUM | RECEPTORS | CASPASE-1 ACTIVATION | CELL BIOLOGY | RNA, Small Interfering - genetics | Salmonella Infections - immunology | Caspase 1 - metabolism | Male | Salmonella Infections - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Apoptosis Regulatory Proteins - genetics | Bone Marrow | Macrophages - immunology | Interleukin-1beta - secretion | Salmonella Infections - pathology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Inflammasomes | Salmonella typhimurium - immunology | Mice, Inbred C57BL | RNA, Messenger - genetics | Lipid Metabolism | Macrophages - cytology | Sterol Regulatory Element Binding Protein 1 - physiology | Enzyme Activation - drug effects | Immunity, Innate | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Synthesis | Molecular genetics | Genes | Physiological aspects | Septic shock | Chemical properties | Genetic transcription | Macrophages | Mitogens | Fatty acids | Protein binding | Steroids | Nlrp1 | SREBP-1a deficiency | Nalp1 | Inflammasome | lipogenesis | Macrophage
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 10, pp. 3935 - 3940
NLRP1 (NLR family, pyrin domain-containing 1) is a contributor to innate immunity involved in intracellular sensing of pathogens, as well as danger signals... 
Proteins | Hydrolysis | Cell death | Teeth | Control loops | Fluorescence | Ligands | Ice | Goods and services tax | Monomers | apoptosis | DEATH | NALP1 | innate immunity | CASPASE-1 ACTIVATION | MULTIDISCIPLINARY SCIENCES
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 50, pp. 88179 - 88188
Genetic variants are linked to vitiligo and associated autoimmune diseases. We performed a meta-analysis to evaluate the effects of the rs12150220, rs2670660,... 
Autoimmune disease | Vitiligo | NLRP1 | Meta-analysis | Polymorphism | RHEUMATOID-ARTHRITIS | vitiligo | meta-analysis | RISK | polymorphism | autoimmune disease | GENE POLYMORPHISMS | CELL BIOLOGY | NALP1 | GENERALIZED VITILIGO | PREDISPOSITION | GENOME-WIDE
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 07/2013, Volume 81, Issue 7, pp. 1266 - 1270
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2011, Volume 70, Issue 4, pp. 668 - 674
Journal Article