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Oncogene, ISSN 0950-9232, 04/2015, Volume 34, Issue 17, pp. 2156 - 2166
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and metastasis. Although multiple cellular miRNAs have been identified to regulate... 
PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | E-CADHERIN | CANCER STEM-CELLS | ENCODED MICRORNAS | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | INVASION | ONCOLOGY | TARGETING PTEN | GENETICS & HEREDITY | EXPRESSION | EPSTEIN-BARR-VIRUS | Nasopharyngeal Neoplasms - genetics | Nasopharyngeal Neoplasms - metabolism | Carcinoma | Herpesvirus 4, Human - genetics | Humans | Nasopharyngeal Neoplasms - virology | Glycogen Synthase Kinase 3 beta | Phosphatidylinositol 3-Kinases - metabolism | RNA, Neoplasm - metabolism | Proto-Oncogene Proteins c-akt - genetics | Nasopharyngeal Neoplasms - pathology | Neoplasm Metastasis | Cell Nucleus - metabolism | RNA, Viral - genetics | Cell Nucleus - pathology | Epithelial-Mesenchymal Transition | Epstein-Barr Virus Infections - genetics | Female | RNA, Viral - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | PTEN Phosphohydrolase - genetics | Nasopharyngeal Carcinoma | Neoplasm Invasiveness | PTEN Phosphohydrolase - biosynthesis | Signal Transduction - genetics | Glycogen Synthase Kinase 3 - metabolism | Epstein-Barr Virus Infections - pathology | Phosphatidylinositol 3-Kinases - genetics | Cell Nucleus - genetics | Glycogen Synthase Kinase 3 - genetics | RNA, Neoplasm - genetics | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | MicroRNA | Biological products | Innovations | Development and progression | Epstein-Barr virus | Genetic aspects | Nasopharyngeal cancer | Gene expression | Health aspects | Cellular biology | Metastasis | Cancer
Journal Article
International Journal of Radiation Biology, ISSN 0955-3002, 05/2019, Volume 95, Issue 5, pp. 597 - 606
Purpose: Radioresistance is an important factor for unsatisfactory prognosis in Nasopharyngeal carcinoma (NPC) patients. Ubiquitous mitochondrial creatine... 
CKMT1 | nasopharyngeal carcinoma | radiosensitivity | STAT3 | REPAIR | MITOCHONDRIAL CREATINE-KINASE | NUCLEAR SCIENCE & TECHNOLOGY | POOR-PROGNOSIS | RADIORESISTANCE | GROWTH | BIOLOGY | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
BMC Cancer, ISSN 1471-2407, 03/2016, Volume 16, Issue 1, p. 190
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e78355
Approximately 30% of patients with Epstein-Barr virus (EBV)-positive advanced nasopharyngeal carcinoma (NPC) display chemoresistance to cisplatin-based... 
CANCER-CELLS | B-CELLS | SURVIVAL | MEMBRANE-PROTEIN 1 | MULTIDISCIPLINARY SCIENCES | EBV | MIR-21 | LATENCY | LIGAND | EXPRESSION | LINES | RNA-Binding Proteins - genetics | Carcinoma | Apoptosis - drug effects | Humans | Nasopharyngeal Neoplasms - virology | MicroRNAs - metabolism | Viral Matrix Proteins - pharmacology | Tetrazolium Salts | Forkhead Transcription Factors - metabolism | Luciferases | Thiazoles | Apoptosis Regulatory Proteins - genetics | Inhibitory Concentration 50 | Viral Matrix Proteins - metabolism | Colony-Forming Units Assay | Gene Expression Regulation, Neoplastic - drug effects | Nasopharyngeal Neoplasms - drug therapy | Real-Time Polymerase Chain Reaction | RNA-Binding Proteins - antagonists & inhibitors | Cell Line | Nasopharyngeal Carcinoma | Cisplatin - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Drug Resistance, Neoplasm - genetics | Fas Ligand Protein - antagonists & inhibitors | Cisplatin - therapeutic use | Signal Transduction - drug effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Fluorescent Antibody Technique | MicroRNAs - genetics | Fas Ligand Protein - genetics | Forkhead Box Protein O3 | Infection | Prognosis | MicroRNA | Tumor necrosis factor | Epstein-Barr virus | B cells | Health aspects | Cisplatin | Apoptosis | Cancer | Cell proliferation | Laboratories | Genes | Crosstalk | Chemoresistance | Viruses | Oncology | Homology | AKT protein | Infections | Metastasis | Proteins | Nasopharyngeal carcinoma | Disease resistance | Signal transduction | Coding | Tumor necrosis factor-TNF | Tumorigenesis | Bioindicators | FOXO3 protein | MiRNA | Ribonucleic acid--RNA | 1-Phosphatidylinositol 3-kinase | Membrane proteins | Medicine | Signaling | Chemotherapy | FasL protein | Cell death | MicroRNAs | Medical prognosis | Cell lines | Biomarkers | Ligands | Latent membrane protein 1 | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0166766
Background Treatment of nasopharyngeal carcinoma requires the application of high dosages of radiation, leading to severe long-term complications in the... 
HYDROXYCHLOROQUINE | APOPTOSIS | 5-FLUOROURACIL | IN-VITRO | INHIBITION | MULTIDISCIPLINARY SCIENCES | INDUCTION | CONTRIBUTES | EPSTEIN-BARR-VIRUS | CHEMOTHERAPY | TEMOZOLOMIDE | RNA, Small Interfering - genetics | Apoptosis - drug effects | Apoptosis - radiation effects | Epithelial Cells - drug effects | Humans | Autophagy-Related Protein 5 - genetics | Autophagy - drug effects | Chloroquine - pharmacology | Nasopharyngeal Neoplasms - radiotherapy | RNA Interference | Autophagy - genetics | Nasopharyngeal Neoplasms - drug therapy | Autophagy-Related Proteins - genetics | Carcinoma - drug therapy | In Situ Nick-End Labeling | Epithelial Cells - radiation effects | Nasopharyngeal Carcinoma | Radiation-Sensitizing Agents - pharmacology | Ubiquitin-Conjugating Enzymes - genetics | Carcinoma - radiotherapy | Autophagy-Related Protein 7 - genetics | Nasal Mucosa - cytology | Beclin-1 - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Cell Proliferation - radiation effects | Autophagy (Cytology) | Care and treatment | Chemotherapy | Chloroquine | Patient outcomes | Causes of | Development and progression | Nasopharyngeal cancer | Drug resistance | Health aspects | Cancer | Pediatrics | Biotechnology | Xenotransplantation | Colorectal cancer | Radiation | Oncology | Autophagy | Cancer therapies | Experiments | Proteins | Nasopharyngeal carcinoma | Cell growth | Xenografts | Sensitizing | Radiation effects | Hematology | Complications | Tumor cells | Melanoma | siRNA | Tumor cell lines | Electron microscopy | Cell lines | Stem cells | Irradiation | In vivo methods and tests | Immunofluorescence | Phagocytosis | Apoptosis
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 382, Issue 1, pp. 21 - 31
Highlights • LMP1 up-regulates HIF-1A transcription and post-transcription in NPC cells. • Down-regulation of RNA-destabilizing proteins contributes to... 
Hematology, Oncology and Palliative Medicine | LMP-1 | Nasopharyngeal carcinoma | EBV | HIF-1α | HIF-1 alpha | TRISTETRAPROLIN | TRANSCRIPTION | FACTOR-I | KAPPA-B | MESSENGER-RNA | GENE | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | HIF-1-ALPHA | BINDING | EPSTEIN-BARR-VIRUS | Nasopharyngeal Neoplasms - genetics | RNA-Binding Proteins - genetics | Up-Regulation | Nasopharyngeal Neoplasms - metabolism | Viral Matrix Proteins - genetics | Herpesvirus 4, Human - genetics | Humans | Carcinoma - virology | Gene Expression Regulation, Neoplastic | Nasopharyngeal Neoplasms - virology | NF-kappa B - metabolism | RNA, Messenger - metabolism | Transfection | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Epstein-Barr Virus Infections - genetics | Tristetraprolin - metabolism | Transcription, Genetic | Viral Matrix Proteins - metabolism | 3' Untranslated Regions | Binding Sites | STAT3 Transcription Factor - metabolism | Nasopharyngeal Carcinoma | Epstein-Barr Virus Infections - virology | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | RNA, Messenger - genetics | Extracellular Signal-Regulated MAP Kinases | RNA Stability | Host-Pathogen Interactions | Tristetraprolin - genetics | Cell Line, Tumor | Carcinoma - genetics | Carcinoma - metabolism | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | Cell Transformation, Viral | RNA-Binding Proteins - metabolism | RNA | Colleges & universities | Viruses | Infections | Kinases | Gene expression | Proteins | Angiogenesis | Hepatitis | Cell growth | Mutagenesis | Plasmids | Rodents | MicroRNAs | Conflicts of interest | Epigenetics | Hypoxia | Mutation | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 1, pp. 64 - 70
Previously, we confirmed the anti-tumor effects of sodium butyrate (NaBu) in nasopharyngeal carcinoma (NPC). However, its molecular mechanisms have not be... 
Nasopharyngeal carcinoma | AKT/mTOR | Sodium butyrate | Autophagy | Apoptosis
Journal Article
Cell Cycle, ISSN 1538-4101, 11/2019, Volume 18, Issue 21, pp. 3044 - 3053
Objective: In this study, long non-coding RNA urothelial carcinoma associated 1 (lncRNA UCA1) in nasopharyngeal carcinoma (NPC) and its effect on the malignant... 
Nasopharyngeal carcinoma | Colony formation | UCA1
Journal Article