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PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180154
Ion channels regulate a variety of physiological processes and represent an important class of drug target. Among the many methods of studying ion channel... 
TARGET | DYE | KV1.3 | NA(V)1.7 | MODULATORS | MULTIDISCIPLINARY SCIENCES | EXTREME PAIN DISORDER | PATCH-CLAMP | MUTATIONS | Cricetulus | High-Throughput Screening Assays - instrumentation | NAV1.3 Voltage-Gated Sodium Channel - genetics | NAV1.1 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.4 Voltage-Gated Sodium Channel - metabolism | Kv1.3 Potassium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - metabolism | NAV1.3 Voltage-Gated Sodium Channel - metabolism | Patch-Clamp Techniques - methods | Kv1.3 Potassium Channel - deficiency | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Sodium Channels - metabolism | NAV1.7 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - genetics | Drug Evaluation, Preclinical | Transgenes | Potassium Channel Blockers - pharmacology | CHO Cells | High-Throughput Screening Assays - methods | Gene Expression | NAV1.4 Voltage-Gated Sodium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - genetics | Rats | Sodium Channel Blockers - pharmacology | Membrane Potentials - physiology | Animals | T-Lymphocytes - cytology | NAV1.6 Voltage-Gated Sodium Channel - metabolism | NAV1.7 Voltage-Gated Sodium Channel - metabolism | NAV1.6 Voltage-Gated Sodium Channel - genetics | Sodium Channels - genetics | Primary Cell Culture | Patch-Clamp Techniques - instrumentation | Ion channels | Information management | Drug discovery | T cells | Modules | Electrophysiology | Patching | Lymphocytes T | Boundaries | Assaying | Channels | Step voltage | Immunology | Pain | Lymphocytes | Sodium channels (voltage-gated) | Physiology | Potassium channels (voltage-gated) | Gold | Platforms | Data points | Automation | Cloning | Pharmacology | Sodium | Antigen-presenting cells | Ligands | Mutation | Recording | Potassium
Journal Article
Journal Article
蛋白质与细胞:英文版, ISSN 1674-800X, 2017, Volume 8, Issue 6, pp. 401 - 438
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0178589
Background Temporomandibular disorders (TMDs) have the highest prevalence in women of reproductive age. The role of estrogen in TMDs and especially in TMDs... 
HUMAN PROSTATE-CANCER | RAT | TEMPOROMANDIBULAR-JOINT | MULTIDISCIPLINARY SCIENCES | ESTROGEN | NEURONS | INFLAMMATORY PAIN | NA(V)1.7 PN1 | SEX-DIFFERENCES | PC12 CELLS | DORSAL-HORN | Estradiol - analogs & derivatives | Luciferases - metabolism | Estrous Cycle - physiology | Receptors, G-Protein-Coupled - metabolism | Temporomandibular Joint Dysfunction Syndrome - genetics | Trigeminal Ganglion - drug effects | Temporomandibular Joint Dysfunction Syndrome - metabolism | Temporomandibular Joint - pathology | Hyperalgesia - pathology | Luciferases - genetics | Estrogen Receptor beta - metabolism | Estrogen Receptor Antagonists - pharmacology | Estrogen Receptor beta - genetics | Temporomandibular Joint - innervation | Nociception - drug effects | Estrogen Receptor alpha - metabolism | Female | NAV1.7 Voltage-Gated Sodium Channel - genetics | Temporomandibular Joint - metabolism | Estrogen Receptor beta - antagonists & inhibitors | Estradiol - pharmacology | Genes, Reporter | Estradiol - metabolism | Promoter Regions, Genetic | Hyperalgesia - metabolism | Ovariectomy | Trigeminal Ganglion - pathology | Gene Expression Regulation | Rats | Trigeminal Ganglion - metabolism | Estrogen Receptor alpha - antagonists & inhibitors | Temporomandibular Joint Dysfunction Syndrome - pathology | Rats, Sprague-Dawley | Freund's Adjuvant | Temporomandibular Joint - drug effects | Animals | Estrogen Receptor alpha - genetics | Hyperalgesia - genetics | NAV1.7 Voltage-Gated Sodium Channel - metabolism | Receptors, G-Protein-Coupled - genetics | Temporomandibular Joint Dysfunction Syndrome - chemically induced | Care and treatment | Ganglionic blocking agents | Receptors | Estrogen | Nerve growth factor | Dosage and administration | Temporomandibular joint disorders | Drug therapy | Health aspects | Estrogens | Genes | Menopause | Disorders | Estrogen receptors | Temporomandibular joint | 17β-Estradiol | Estrus cycle | Kinases | Guanine nucleotide-binding protein | Assaying | Pain | Smear | Sodium channels (voltage-gated) | Potassium channels (voltage-gated) | Age | Enzyme-linked immunosorbent assay | Food | Head | Pain perception | Estrus | Thresholds | Neurons | Vagina | Inflammation | Real time | Polymerase chain reaction | Sex hormones | Sodium | Food intake | Pheochromocytoma cells | Perception | Plasma levels | Mutation | Trigeminal ganglion
Journal Article
Science, ISSN 0036-8075, 12/2015, Volume 350, Issue 6267, pp. aac5464 - aac5464
Journal Article
Journal Article