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FASEB Journal, ISSN 0892-6638, 2000, Volume 14, Issue 10, pp. 1455 - 1463
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2017, Volume 114, Issue 16, pp. E3243 - E3250
Rett syndrome (RTT) is an X-linked neurological disorder caused by mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. The majority of RTT missense... 
MeCP2 | Intellectual disability | TBL proteins | NCoR/SMRT | Rett syndrome | SEVERE MENTAL-RETARDATION | MULTIDISCIPLINARY SCIENCES | SYMPTOMS | FEATURES | CHROMOSOMAL-PROTEIN | DNA | PURIFICATION | DUPLICATION | MUTATIONS | BINDING | intellectual disability | Genetic aspects | Gene mutations | Health aspects | Biological Sciences | PNAS Plus | SMRT | NCoR
Journal Article
Cell Regeneration, ISSN 2045-9769, 06/2019, Volume 8, Issue 1, pp. 21 - 29
Class IIa histone deacetylases (HDACs) are a subfamily of HDACs with important functions in development and adult tissue homeostasis. As opposed to other... 
iPSCs | Class IIa HDACs | Somatic cell reprogramming | Mesenchymal-to-epithelial transition | NCoR/SMRT co-repressors | Pluripotency
Journal Article
Cell Biology International, ISSN 1065-6995, 02/2017, Volume 41, Issue 2, pp. 204 - 212
Journal Article
Genes and Development, ISSN 0890-9369, 12/2018, Volume 32, Issue 23-24, pp. 1514 - 1524
Duplication of the X-linked MECP2 gene causes a severe neurological syndrome whose molecular basis is poorly understood. To determine the contribution of known... 
histone deacetylase 3 | NCoR | MeCP2 | COMPLEX | RETT-SYNDROME | N-COR | HISTONE-DEACETYLASE ACTIVITY | TAU | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | CHROMOSOMAL-PROTEIN | REPRESSION | GENETICS & HEREDITY | MUTATIONS | MOLECULAR-BASIS | BINDING | Research Paper
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2006, Volume 398, Issue 3, pp. 461 - 467
In eukaryotic cells, the Ccr4-Not complex can regulate mRNA metabolism at various levels. Previously, we showed that promoter targeting of the CNOT2 subunit... 
Ccr4-Not complex | Histone deacetylase | Chromatin | Silencing mediator for retinoic acid receptor and thyroid-hormone receptor (SMRT)/nuclear hormone receptor co-repressor (NCoR) | Protein-protein interaction | Transcription regulation | transcription regulation | SIGNALING PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-COR | receptor (SMRT)/nuclear hormone receptor co-repressor (NCoR) | COMPONENTS | PROTEIN INTERACTS | chromatin | histone deacetylase | NUCLEAR HORMONE-RECEPTORS | RECEPTOR COREPRESSOR COMPLEX | YEAST | IN-VIVO | protein-protein interaction | II HISTONE DEACETYLASES | MESSENGER-RNA METABOLISM | silencing mediator for retinoic acid receptor and thyroid-hormone | Cell Line | Protein Subunits | Histone Deacetylases - genetics | Nuclear Receptor Co-Repressor 2 | Down-Regulation | Humans | Nuclear Receptor Co-Repressor 1 | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - metabolism | Two-Hybrid System Techniques | Transcription, Genetic | Nuclear Proteins - genetics | Repressor Proteins - metabolism | SANT, SWI3, ADA2, N-CoR and TFIIIB | SMRT, silencing mediator for retinoic acid receptor and thyroid-hormone receptor | TBLR1, TBL-related 1 | silencing mediator for retinoic acid receptor and thyroid-hormone receptor (SMRT) | protein–protein interaction | mSin3A, murine Sin3A | ERα, oestrogen receptor α | RD1, repression domain 1 | SAGA, Spt-Ada-Gcn5-acetyltransferase | Ccr4–Not complex | HEK-293T cells, HEK-293 cells (human embryonic kidney cells) expressing the large T-antigen of SV40 (simian virus 40) | LexA, Lex A repressor | CRD1, cell cycle regulatory domain 1 | RID, receptor interaction domain | MyoD, myogenic differentiation antigen D | HDAC, histone deacetylase | NCoR, nuclear hormone receptor co-repressor | Gcn5, general control of amino acid synthesis protein 5 | GPS2, G-protein pathway suppressor 2 | TSA, trichostatin A | Bcl-6, B-cell lymphocytic-leukaemia proto-oncogene 6 | DBD, DNA-binding domain | pol II, RNA polymerase II | TBL1, transducin β-like protein 1 | nuclear hormone receptor co-repressor (NCoR) | Caf1, Ccr4-associated factor 1 | Sin3A, Swi-independent 3A | CMV, cytomegalovirus | RXRβ, retinoic X receptor β | TFIID, transcription factor II D
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2017, Volume 114, Issue 15, pp. 3981 - 3986
ZBTB transcription factors orchestrate gene transcription during tissue development. However, their roles in glioblastoma (GBM) remain unexplored. Here,... 
BCL6 | NCoR | AXL | Glioblastoma multiforme | ZBTB | glioblastoma multiforme | MULTIDISCIPLINARY SCIENCES | CELL-GROWTH | BTB DOMAIN | BREAST-CANCER | B-CELLS | IN-VITRO | GROWTH ARREST | PROBE LEVEL | INHIBITOR | HUMAN GLIOBLASTOMA-MULTIFORME | Biological Sciences
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2012, Volume 134, Issue 2, pp. 569 - 581
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 18, pp. 13444 - 13453
Pregnant women show a low level of protein S (PS) in plasma, which is known to be a risk for deep venous thrombosis. 17 beta-Estradiol (E-2), an estrogen that... 
C4B-BINDING PROTEIN | S DEFICIENCY | TRANSCRIPTION FACTORS | PATHWAYS | BREAST-CANCER CELLS | K-DEPENDENT PROTEIN | HISTONE DEACETYLASES | SP1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROMOTER | BINDING | Gene Regulation | RIP140 | NCoR-SMRT | PROS1 | Estrogen
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 03/2009, Volume 23, Issue 6, pp. 681 - 693
Journal Article
BBA - General Subjects, ISSN 0304-4165, 07/2013, Volume 1830, Issue 7, pp. 3876 - 3881
Journal Article
BMC research notes, ISSN 1756-0500, 06/2019, Volume 12, Issue 1, pp. 343 - 6
The NCoR-1 and NCoR-2 corepressors are products of an early gene duplication near the beginning of vertebrate evolution and play both overlapping and divergent... 
Physiological aspects | Messenger RNA | Vertebrates | Alternative splicing | Placenta | Exons | Evolution | Gene duplication | mRNA | Kinases | Nuclear hormone receptors | Transcriptional regulation | Nuclear receptors | Corepressors | Alternative mRNA splicing
Journal Article