X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (859) 859
Publication (134) 134
Newspaper Article (17) 17
Book Review (11) 11
Book Chapter (8) 8
Conference Proceeding (5) 5
Book / eBook (4) 4
Newsletter (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
negative cooperativity (437) 437
index medicus (413) 413
biochemistry & molecular biology (326) 326
humans (286) 286
animals (254) 254
proteins (163) 163
kinetics (155) 155
protein binding (144) 144
research (139) 139
binding sites (138) 138
cell biology (118) 118
escherichia-coli (117) 117
models, molecular (116) 116
ligands (112) 112
biophysics (110) 110
research article (110) 110
signal transduction (109) 109
multidisciplinary sciences (107) 107
crystal-structure (106) 106
biology (105) 105
binding (104) 104
gram-negative bacteria (100) 100
protein conformation (98) 98
analysis (91) 91
article (89) 89
physiological aspects (87) 87
negative feedback (82) 82
biochemistry (80) 80
models, biological (79) 79
amino acid sequence (77) 77
gene expression (77) 77
mutation (76) 76
science (74) 74
bacteria (73) 73
molecular sequence data (73) 73
medicine (72) 72
enzymes (68) 68
protein structure, tertiary (67) 67
mice (64) 64
dimerization (62) 62
activation (61) 61
insulin - metabolism (56) 56
cooperativity (55) 55
genetic aspects (54) 54
receptor, insulin - metabolism (54) 54
allosteric regulation (52) 52
microbiology (52) 52
structural basis (52) 52
expression (48) 48
phosphorylation (48) 48
e coli (47) 47
receptors (47) 47
feedback (46) 46
insulin (46) 46
kinases (46) 46
protein (46) 46
ligand-binding (43) 43
protein multimerization (43) 43
mechanism (42) 42
rats (42) 42
dna (40) 40
endocrinology & metabolism (40) 40
pharmacology & pharmacy (40) 40
structure (40) 40
crystallography, x-ray (39) 39
genes (39) 39
molecular biology (39) 39
escherichia coli (37) 37
computer simulation (36) 36
female (36) 36
bacterial proteins - metabolism (35) 35
catalysis (35) 35
gene-expression (34) 34
escherichia coli - metabolism (33) 33
male (33) 33
thermodynamics (33) 33
dynamics (32) 32
escherichia coli - genetics (32) 32
escherichia coli proteins - metabolism (32) 32
life sciences (32) 32
substrate specificity (32) 32
transcription factors (32) 32
biochemical research methods (31) 31
cell line (31) 31
crystal structure (31) 31
dna-binding proteins - metabolism (31) 31
mathematical & computational biology (31) 31
negative regulation (31) 31
physiology (31) 31
cancer (30) 30
cells (30) 30
chemical properties (30) 30
mathematical models (30) 30
structure-activity relationship (30) 30
biological sciences (29) 29
cell membrane - metabolism (29) 29
gene (29) 29
protein structure, secondary (29) 29
protein-coupled receptors (29) 29
temperature (29) 29
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Molecular BioSystems, ISSN 1742-206X, 2014, Volume 10, Issue 7, pp. 1824 - 1832
Cooperativity of ligand-receptor binding influences the input-output behavior of a biochemical system and thus is an important determinant of its physiological... 
SIGNAL-TRANSDUCTION | GROWTH-FACTOR RECEPTOR | NEGATIVE COOPERATIVITY | LIGAND-BINDING | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE CASCADE | MODEL | LAMPREY HEMOGLOBIN | ESTROGEN-RECEPTOR | EGF RECEPTOR | Proteins - metabolism | Models, Chemical | Allosteric Regulation | Protein Binding | Ligands | Kinetics | Proteins - chemistry | Binding Sites | Dimerization
Journal Article
ACS Synthetic Biology, ISSN 2161-5063, 06/2019, Volume 8, Issue 6, pp. 1294 - 1302
Positive cooperativity in receptor ligand binding plays an important role in cell signaling as it generates an ultrasensitive response, a requirement for... 
positive feedback | negative and positive cooperativity | bistability | bifurcation analysis | NETWORK | ACTIVATION | BIOCHEMICAL RESEARCH METHODS | BISTABLE SWITCHES | FEEDBACK LOOP | ULTRASENSITIVITY | HETEROGENEITY | TOGGLE SWITCH | MEMORY | MULTISITE PROTEIN-PHOSPHORYLATION | EXPRESSION
Journal Article
Physical Review Letters, ISSN 0031-9007, 06/2016, Volume 116, Issue 25, pp. 258104 - 258104
Negative autoregulation is universally found across organisms. In the bacterium Escherichia coli, transcription factors often repress their own expression to... 
HSP90 | DESIGN | PHYSICS, MULTIDISCIPLINARY | STABILITY | ESCHERICHIA-COLI | SENSITIVITY | COMMON | PROTEINS | EXPRESSION | RESIDUES | FEEDBACK | Mutations | Networks | Negative feedback | Genes | Mathematical models | Robustness | Speciation | Strength
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 4093 - 13
Bacterial communities have rich social lives. A well-established interaction involves the exchange of a public good in Pseudomonas populations, where the... 
MICROBES | GRAM-NEGATIVE BACTERIA | GAME DYNAMICS | AERUGINOSA | EVOLUTION | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | SIDEROPHORE | SELECTION | PYOVERDIN-PRODUCING PSEUDOMONAS | SOCIOBIOLOGY | Metapopulations | Social interactions | Pyoverdine | Public good | Quantitative Biology - Populations and Evolution
Journal Article
Journal of Physical Chemistry Letters, ISSN 1948-7185, 03/2019, Volume 10, Issue 6, pp. 1272 - 1278
Pin1 is a two-domain peptidyl-prolyl isomerase (PPIase) associated with neurodegeneration and tumorigenesis. The two domains, a WW and a PPIase domain, are... 
PATHWAYS | STRUCTURAL BASIS | NEGATIVE REGULATION | MATERIALS SCIENCE, MULTIDISCIPLINARY | ISOMERIZATION | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | PROLYL | SUBSTRATE RECOGNITION
Journal Article
BIOSCIENCE REPORTS, ISSN 0144-8463, 09/2019, Volume 39, Issue 9, p. BSR20191874
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 02/2017, Volume 56, Issue 6, pp. 845 - 855
Journal Article
Biochemical Society transactions, ISSN 0300-5127, 2/2012, Volume 40, Issue 1, pp. 15 - 19
Scatchard analyses of the binding of EGF to its receptor yield concave up Scatchard plots, indicative of some type of heterogenity in ligand binding affinity.... 
negative cooperativity | EGF receptor | saturation binding isotherms
Journal Article