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Nature cell biology, ISSN 1476-4679, 11/2019, Volume 21, Issue 11, pp. 1413 - 1424
Tumours depend on altered rates of protein synthesis for growth and survival, which suggests that mechanisms controlling mRNA translation may be exploitable... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Biosynthesis | Cell Proliferation | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Male | Eukaryotic Initiation Factor-2B - genetics | HEK293 Cells | Eukaryotic Initiation Factor-2 - metabolism | Female | Colorectal Neoplasms - metabolism | Protein-Serine-Threonine Kinases - metabolism | Adenomatous Polyposis Coli Protein - genetics | Colorectal Neoplasms - mortality | Signal Transduction | Colon - pathology | HCT116 Cells | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-myc - metabolism | Colon - metabolism | Xenograft Model Antitumor Assays | Feedback, Physiological | Animals | Eukaryotic Initiation Factor-2 - genetics | Adenomatous Polyposis Coli Protein - metabolism | Survival Analysis | Cell Line, Tumor | Eukaryotic Initiation Factor-2B - metabolism | Mice | Proto-Oncogene Proteins c-myc - genetics | Colorectal Neoplasms - pathology | Eukaryotic Initiation Factor-2B - antagonists & inhibitors | Cell Movement | Phosphorylation | Colorectal carcinoma | Energy sources | Amino acids | Feedback loops | mRNA | Myc protein | Nucleotides | Kinases | Proteins | Negative feedback | Energy resources | Organoids | Feedback | Intestine | Dependence | Adenomatous polyposis coli protein | Translation | Translation initiation | Protein biosynthesis | Adenomatous polyposis coli | Depletion | Protein synthesis | Control theory | Tumors | Apoptosis | Index Medicus | eIF2α | translation | colorectal cancer | APC | eIF2B5 | MYC
Journal Article
Oncology letters, ISSN 1792-1074, 2017, Volume 14, Issue 2, pp. 1403 - 1410
Zinc finger and BTB domain containing 7A (ZBTB7A) is aberrantly expressed in breast cancer, but the involvement of ZBTB7A in breast cancer remains... 
Zinc finger and BTB domain containing 7A | Negative feedback | Breast cancer | Metastasis | Transforming growth factor-β1 | Life Sciences & Biomedicine | Oncology | Science & Technology
Journal Article
Nucleic acids research, ISSN 1362-4962, 08/2018, Volume 46, Issue 14, pp. 7339 - 7353
.... Biochemical and functional characterization of this target demonstrated that RBS1 polypeptide physically interacts with a predicted thermodynamically stable stem-loop upregulating mRNA translation... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Gene expression | Protein interaction | RNA and RNA-protein complexes
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2018, Volume 115, Issue 31, pp. 7869 - 7878
Journal Article
PloS one, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e35440 - e35440
Background: The majority of human cancer deaths are caused by metastasis. The metastatic dissemination is initiated by the breakdown of epithelial cell... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Epithelial-Mesenchymal Transition - physiology | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Repressor Proteins - genetics | MicroRNAs - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Epithelial-Mesenchymal Transition - genetics | Reverse Transcriptase Polymerase Chain Reaction | Zinc Finger E-box Binding Homeobox 2 | Cell Movement - genetics | Cell Movement - physiology | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Twist-Related Protein 1 - genetics | Cell Line, Tumor | MicroRNAs - genetics | Nuclear Proteins - genetics | Twist-Related Protein 1 - metabolism | Snail Family Transcription Factors | Repressor Proteins - metabolism | Zinc Finger E-box-Binding Homeobox 1 | MicroRNA | Analysis | Stem cells | Development and progression | Genetic transcription | DNA binding proteins | Metastasis | Cell differentiation | Health aspects | Regulators | Transcription factors | Mesenchyme | Epithelial cells | Leukemia | Homeostasis | Switching theory | Feedback loops | Metastases | Negative feedback | Feedback | Cooperation | Cell cycle | Plasticity | miRNA | Life sciences | Computer simulation | Breast cancer | Gene expression | MicroRNAs | Computer applications | Cytoskeleton | Plastic properties | Control theory | Snail protein | Prostate cancer | Cancer | Index Medicus
Journal Article