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Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 5, pp. e1004114 - e1004114
Trypanosomatid parasites are the causative agents of many neglected tropical diseases and there is currently considerable interest in targeting endogenous... 
MECHANISM | NITROGEN-CONTAINING BISPHOSPHONATES | TRYPANOSOMA-CRUZI | MICROBIOLOGY | CRYSTALLOGRAPHY | MODEL | FARNESYL DIPHOSPHATE SYNTHASE | IN-VITRO | VIROLOGY | ISOPRENOID BIOSYNTHESIS | INHIBITORS | CHOLESTEROL-BIOSYNTHESIS | PARASITOLOGY | Polyisoprenyl Phosphates - chemistry | Sesquiterpenes - metabolism | Humans | Cercopithecus aethiops | Crystallography, X-Ray | Trypanocidal Agents - chemistry | Trypanosoma cruzi - enzymology | Farnesyl-Diphosphate Farnesyltransferase - chemistry | Enzyme Inhibitors - chemistry | Trypanocidal Agents - therapeutic use | Vero Cells | Molecular Targeted Therapy - methods | Trypanocidal Agents - metabolism | Sesquiterpenes - chemistry | Enzyme Inhibitors - metabolism | Quinuclidines - pharmacology | Enzyme Inhibitors - pharmacology | Models, Molecular | Diphosphonates - metabolism | Enzyme Inhibitors - therapeutic use | Polyisoprenyl Phosphates - metabolism | Farnesyl-Diphosphate Farnesyltransferase - metabolism | Animals | Trypanocidal Agents - pharmacology | Farnesyl-Diphosphate Farnesyltransferase - antagonists & inhibitors | Diphosphonates - chemistry | Chagas Disease - drug therapy | Protein Binding | Quinuclidines - chemistry | Quinuclidines - metabolism | Diphosphonates - pharmacology | Phosphonates | Physiological aspects | Squalene | Chagas' disease | Diagnosis | Research | Drug therapy | Health aspects | Index Medicus | Research & development | Protozoa | R&D | Disease | Sterols | Ligands | Biosynthesis | Parasites | Tropical diseases | Cholesterol
Journal Article
Transactions of The Royal Society of Tropical Medicine and Hygiene, ISSN 0035-9203, 06/2016, Volume 110, Issue 6, pp. 319 - 320
Journal Article
Journal of Drug Targeting, ISSN 1061-186X, 08/2019, Volume 27, Issue 7, pp. 767 - 779
Neglected tropical diseases caused by protozoan parasites affect the life of millions of people worldwide, causing mortality, morbidity and high economic and... 
drugs | photodynamic therapy | Heme | trypanosomiasis | neglected diseases | heme-oxygenase | malaria | leishmaniasis
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e84981 - e84981
Placental malaria is a major health problem for both pregnant women and their fetuses in malaria endemic regions. It is triggered by the accumulation of... 
ADHESION | PREGNANCY-ASSOCIATED MALARIA | FALCIPARUM-INFECTED ERYTHROCYTES | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULINS | MEMBRANE PROTEIN-1 | CHONDROITIN SULFATE-A | INHIBITORY ANTIBODIES | PLACENTAL MALARIA | EPITOPES | Immunoglobulin Heavy Chains - biosynthesis | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Chondroitin Sulfates - metabolism | Humans | Immunoglobulin Heavy Chains - chemistry | Molecular Sequence Data | Peptide Library | Plasmodium falciparum - immunology | Recombinant Proteins - biosynthesis | Single-Domain Antibodies - immunology | Epitopes - immunology | Immunoglobulin Heavy Chains - immunology | Plasmodium falciparum - chemistry | Amino Acid Sequence | Antigens, Protozoan - chemistry | Recombinant Proteins - chemistry | Chondroitin Sulfates - chemistry | Camelids, New World | Sequence Alignment | Animals | Recombinant Proteins - immunology | Single-Domain Antibodies - chemistry | Malaria, Falciparum - immunology | Protein Binding | Epitopes - chemistry | Erythrocytes - parasitology | Single-Domain Antibodies - biosynthesis | Plasmodium falciparum | Malaria | Pregnant women | Immunoglobulin G | Vaccines | Sulfates | Antigenic determinants | Protein binding | Erythrocytes | Antibodies | Chains | Accumulation | Proteins | Red blood cells | Immunology | Technology | Libraries | Vector-borne diseases | Antigens | Parasitology | Immunoglobulins | Immune response | Anemia | Fetuses | Epitopes | Adhesion | Pregnancy | Immune systems | Hospitals | Placenta | Infectious diseases | Immunogenicity | Lymphocytes B | Chondroitin sulfate | Sulfate | Laboratory animals | Binding sites | Index Medicus
Journal Article