X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
neoantigens (305) 305
humans (265) 265
index medicus (257) 257
immunotherapy (256) 256
oncology (208) 208
neoantigen (201) 201
cancer (184) 184
immunology (180) 180
animals (124) 124
antigens (106) 106
melanoma (105) 105
mutation (96) 96
pd-1 blockade (95) 95
lymphocytes (91) 91
tumors (89) 89
t cells (88) 88
female (81) 81
expression (71) 71
neoplasms - immunology (70) 70
tumor-infiltrating lymphocytes (68) 68
ctla-4 blockade (66) 66
male (66) 66
t-cells (65) 65
tumor antigens (61) 61
antigens, neoplasm - immunology (59) 59
lymphocytes t (54) 54
article (53) 53
neoplasms - therapy (51) 51
immunotherapy - methods (49) 49
proteins (49) 49
vaccines (49) 49
checkpoint blockade (48) 48
dendritic cells (48) 48
peptides (48) 48
antibodies (45) 45
biochemistry & molecular biology (45) 45
care and treatment (45) 45
immune response (45) 45
review (45) 45
middle aged (44) 44
blockade (43) 43
cancer-immunotherapy (43) 43
identification (43) 43
metastatic melanoma (43) 43
mutations (43) 43
adult (42) 42
cell biology (42) 42
antigen (40) 40
analysis (39) 39
cancer immunotherapy (39) 39
immune checkpoint (39) 39
research (39) 39
tumor (39) 39
therapy (38) 38
exome analysis reveals (37) 37
vaccination (37) 37
chemotherapy (36) 36
immune system (36) 36
sensitivity (36) 36
genetic aspects (35) 35
landscape (35) 35
mice (35) 35
aged (33) 33
biomarkers (33) 33
cells (32) 32
immunity (32) 32
mass-spectrometry (32) 32
vaccine (32) 32
lung cancer (31) 31
neoplasms - genetics (31) 31
nivolumab (31) 31
cancer vaccines (30) 30
genomics (30) 30
immunogenicity (30) 30
medicine, research & experimental (30) 30
metastasis (30) 30
patients (30) 30
gene expression (29) 29
activation (28) 28
apoptosis (28) 28
deoxyribonucleic acid--dna (28) 28
drug therapy (28) 28
rats (28) 28
breast cancer (27) 27
immune checkpoint blockade (27) 27
medical research (27) 27
multidisciplinary sciences (27) 27
neoantigen load (27) 27
pharmacology & pharmacy (27) 27
t-lymphocytes - immunology (27) 27
tumor microenvironment (27) 27
cytotoxicity (26) 26
genetics & heredity (26) 26
health aspects (26) 26
human-melanoma (26) 26
usage (26) 26
antigens, neoplasm - genetics (25) 25
pd-l1 (25) 25
cancer therapies (24) 24
clinical trials (24) 24
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (611) 611
French (7) 7
German (4) 4
Chinese (1) 1
Japanese (1) 1
Persian (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


BLOOD, ISSN 0006-4971, 07/2019, Volume 134, Issue 2, pp. 108 - 109
In this issue of Blood, Schischlik et al describe a streamlined analysis of the granulocyte transcriptome (ie, messenger RNA [mRNA]) of 113 patients with... 
HEMATOLOGY | NEOANTIGENS | MUTATIONS
Journal Article
Bulletin du Cancer, ISSN 0007-4551, 12/2018, Volume 105, pp. S113 - S120
The new vaccine approaches in oncology: The concept of cancer vaccine relies on the induction of an adaptive immune response against antigens presented by... 
Neoantigens | Checkpoints | Adjuvant | Vaccine
Journal Article
Annals of Oncology, ISSN 0923-7534, 01/2018, Volume 29, Issue 1, pp. 271 - 279
Abstract Background Cancer mutations generate novel (neo-)peptides recognised by T cells, but the determinants of recognition are not well characterised. The... 
Neoantigen prediction | Immunotherapy | Peptide immunogenicity | Immunoinformatics | CTLA-4 BLOCKADE | peptide immunogenicity | LANDSCAPE | neoantigen prediction | SENSITIVITY | immunoinformatics | ANTIGEN PRESENTATION | MASS-SPECTROMETRY | CHECKPOINT BLOCKADE | IMMUNOGENICITY | ONCOLOGY | immunotherapy | NEOANTIGENS | MUTATIONS | REVEALS | Original articles | Editor's Choice
Journal Article
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, ISSN 0027-8874, 12/2017, Volume 109, Issue 12
Journal Article
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 4, pp. 934 - 949.e16
Journal Article
Cancer Research, ISSN 0008-5472, 01/2019, Volume 79, Issue 1, pp. 7 - 20
Osteosarcoma is the most common primary bone malignancy, and the lung is the most frequent site of metastasis. The limited understanding of the tumoral... 
MUTATIONAL PROCESSES | SIGNATURES | ONCOLOGY | PATHWAY | TUMOR | PATTERNS | NEOANTIGENS | CHEMOTHERAPY
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2019, Volume 25, Issue 3, pp. 1063 - 1069
Purpose: Tumor mutation burden (TMB) is a biomarker of response to immune checkpoint blockade (ICB). The impact of TMB on outcomes with targeted therapies has... 
CTLA-4 BLOCKADE | FACTOR-RECEPTOR GENE | GEFITINIB | CARBOPLATIN | OSIMERTINIB | ONCOLOGY | LANDSCAPE | ADENOCARCINOMA | SENSITIVITY | NEOANTIGENS | PACLITAXEL
Journal Article
Nature, ISSN 0028-0836, 05/2018, Volume 557, Issue 7706, pp. 575 - 579
Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving to be effective at restoring T cell-mediated immune responses that can... 
HETEROGENEITY | RESPONSES | IMMUNOTHERAPY | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | NEOANTIGENS | PD-1 | ANTITUMOR | EXHAUSTION
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 13, pp. 11009 - 11019
Neoantigens are the main targets of tumor-specific T cells reactivated by immune checkpoint-blocking antibodies or when using tumor-infiltrating T cells for... 
Neoantigens | TCR-engineered T cells | T cell receptor | Neoantigen-specific T cells
Journal Article
by McGranahan, Nicholas and Rosenthal, Rachel and Hiley, Crispin and Hiley, Crispin T and Rowan, Andrew and Rowan, Andrew J and Watkins, Thomas B.K and Wilson, Gareth and Wilson, Gareth A and Birkbak, Nicolai J and Veeriah, Selvaraju and Van Loo, Peter and Herrero, Javier and Swanton, Charles and Jamal-Hanjani, Mariam and Shafi, Seema and Czyzewska-Khan, Justyna and Johnson, Benjamin and Johnson, Diana and Laycock, Joanne and Bosshard-Carter, Leticia and Gorman, Pat and Hynds, Robert E and Horswell, Stuart and Mitter, Richard and Escudero, Mickael and Stewart, Aengus and Xu, Hang and Turajlic, Samra and Abbosh, Christopher and Goldman, Jacki and Stone, Richard Kevin and Denner, Tamara and Matthews, Nik and Matthews, Sue and Elgar, Greg and Ward, Sophia and Costa, Marta and Begum, Sharmin and Phillimore, Ben and Chambers, Tim and Nye, Emma and Graca, Sofia and Al Bakir, Maise and Joshi, Kroopa and Furness, Andrew and Ben Aissa, Assma and Wong, Yien Ning Sophia and Georgiou, Andy and Quezada, Sergio and Hartley, John A and Lowe, Helen L and Lawrence, David and Hayward, Martin and Panagiotopoulos, Nikolaos and Kolvekar, Shyam and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Simeon, Celia and Hector, Gemma and Smith, Amy and Smith, Sean and Smith, Elaine and Aranda, Marie and Novelli, Marco and Oukrif, Dahmane and Janes, Sam M and Thakrar, Ricky and Forster, Martin and Ahmad, Tanya and Lee, Siow Ming and Papadatos-Pastos, Dionysis and Carnell, Dawn and Mendes, Ruheena and George, Jeremy and Navani, Neal and Ahmed, Asia and Taylor, Paul and Taylor, Magali and Choudhary, Junaid and Summers, Yvonne and Califano, Raffaele and Shah, Rajesh and Krysiak, Piotr and Rammohan, Kendadai and Fontaine, Eustace and Booton, Richard and Evison, Matthew and Crosbie, Phil and Moss, Stuart and Idries, Faiza and Joseph, Leena and Bishop, Paul and Chaturved, Anshuman and Quinn, Anne Marie and Doran, Helen and Leek, Angela and Harrison, Phil and Moore, Katrina and ... and TRACERx Consortium
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 6, pp. 1259 - 1271.e11
Journal Article
JOURNAL OF THORACIC ONCOLOGY, ISSN 1556-0864, 05/2017, Volume 12, Issue 5, pp. 791 - 803
Introduction: The interaction of immune cells and cancer cells shapes the immunosuppressive tumor microenvironment. For successful cancer immunotherapy,... 
CELLS | NETMHCPAN | LANDSCAPE | Lung cancer | Transcriptome | SENSITIVITY | Immunogram | DOCETAXEL | Cancer-immunity cycle | ONCOLOGY | RESPIRATORY SYSTEM | NEOANTIGENS | MUTATIONS | BLOCKADE | NIVOLUMAB | BINDING | Neoantigen
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 04/2019, Volume 10, p. 824
Tumor vaccines are an important asset in the field of cancer immunotherapy. Whether prophylactic or therapeutic, these vaccines aim to enhance the T... 
intratumor heterogeneity | tumor vaccines | DENDRITIC CELLS | multiplex neoantigen vaccines | neoantigens | POPULATIONS | INDUCTION | IMMUNOLOGY | NEOANTIGEN VACCINE | EVOLUTION | GENE | IMMUNOTHERAPY | DIVERSITY | personalized vaccines | T-CELLS | ANTIGEN | Vaccines | T cells | Tumor antigens | Vaccination | Tumors
Journal Article
NATURE, ISSN 0028-0836, 02/2019, Volume 566, Issue 7743, pp. 270 - 270
There is growing evidence that tumour neoantigens have important roles in generating spontaneous antitumour immune responses and predicting clinical responses... 
READ ALIGNMENT | CD8(+) | MULTIDISCIPLINARY SCIENCES | NEOANTIGENS | GENERATION | LEUKEMIA | IDENTIFICATION | REVEALS
Journal Article
Science Translational Medicine, ISSN 1946-6234, 12/2018, Volume 10, Issue 470, p. eaau5516
Tumor-specific antigens (TSAs) represent ideal targets for cancer immunotherapy, but few have been identified thus far. We therefore developed a proteogenomic... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | REPERTOIRE | GENE | IMMUNOTHERAPY | FREQUENCY | NEOANTIGENS | DIVERSITY | IDENTIFICATION | MASS-SPECTROMETRY | LYMPHOCYTES | CELL BIOLOGY
Journal Article
Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6349, pp. 409 - 413
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Bioindicators | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis
Journal Article