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PloS one, 2013, Volume 8, Issue 8, p. e73554
The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension... 
Nephrons - cytology | Animals | Bone Morphogenetic Protein 7 - genetics | Cell Differentiation | Kidney - cytology | Mice | Stem Cells - cytology | Bone Morphogenetic Protein 7 - physiology | Apoptosis | Mice, Knockout
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2018, Volume 29, Issue 3, pp. 785 - 805
Human kidney function is underpinned by approximately 1,000,000 nephrons, although the number varies substantially, and low nephron number is linked to... 
CELLS | RENAL PELVIS | PROGENITOR POPULATION | BRANCHING MORPHOGENESIS | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | NEPHRON NUMBER | DIFFERENTIATION | IDENTIFICATION | HYPERTENSION | MICRODISSECTION | nephron | human genetics | kidney development | Basic Research
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 02/2018, Volume 29, Issue 2, pp. 532 - 544
Intrinsic ureteropelvic junction obstruction is the most common cause of congenital hydronephrosis, yet the underlying pathogenesis is undefined. Hedgehog... 
MORPHOGENESIS | SMOOTH-MUSCLE | SHH | SONIC HEDGEHOG | UROLOGY & NEPHROLOGY | PATCHED GENE | INTERMEDIATE MESODERM | MAMMALIAN KIDNEY | MESENCHYME | NEPHRON PROGENITOR POPULATION | EXPRESSION | Index Medicus | kidney development | signaling | obstructive | pediatrics | nephropathy | transgenic mouse | Basic Research
Journal Article
Developmental Biology, ISSN 0012-1606, 2011, Volume 360, Issue 1, pp. 110 - 122
Journal Article
EMBO reports, ISSN 1469-221X, 04/2019, Volume 20, Issue 4, pp. e47483 - n/a
Nephron formation continues throughout kidney morphogenesis in both mice and humans. Lineage tracing studies in mice identified a self‐renewing Six2‐expressing... 
CRSIPR | fate mapping | Cas9 | kidney organoid | lineage tracing | pluripotent stem cell | PROGENITOR POPULATION | DIVERGENT FEATURES | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | GENERATION | CRISPR | Kidneys | Wnt protein | Epithelial cells | Feasibility studies | Mapping | Epithelium | Nephrons | Morphogenesis | Cell fate | Organoids | Stem cells | Mice | Ureter | Pluripotency | Niches | Inhibitory postsynaptic potentials
Journal Article