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Pediatrics, ISSN 0031-4005, 08/2009, Volume 124, Issue 2, pp. 747 - 757
The therapeutic approach to childhood nephrotic syndrome is based on a series of studies that began with an international collaborative effort sponsored by the... 
Kidney disease | Nephrosis | Pediatric | Proteinuria | LONG-TERM | MINIMAL CHANGE | STEROID-RESISTANT | proteinuria | kidney disease | INITIAL TREATMENT | RANDOMIZED-TRIAL | NEPHROLOGY STUDY-GROUP | pediatric | PEDIATRICS | nephrosis | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | STANDARD PREDNISONE THERAPY | MYCOPHENOLATE-MOFETIL | THROMBOEMBOLIC COMPLICATIONS | Glucocorticoids - therapeutic use | Kidney - pathology | Humans | Immunosuppressive Agents - therapeutic use | Antineoplastic Agents - therapeutic use | Nephrotic Syndrome - drug therapy | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Kidney Function Tests | Dose-Response Relationship, Drug | Antineoplastic Agents - adverse effects | Nephrosis, Lipoid - drug therapy | Drug Therapy, Combination | Child | Nephrotic Syndrome - diagnosis | Drug Resistance | Glucocorticoids - adverse effects | Nephrosis, Lipoid - diagnosis | Prednisone - adverse effects | Drug Administration Schedule | Nephrotic Syndrome - pathology | Combined Modality Therapy | Cyclosporine - therapeutic use | Mycophenolic Acid - adverse effects | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Nephrosis, Lipoid - pathology | Biopsy | Cyclosporine - adverse effects | Immunosuppressive Agents - adverse effects | Nephrosis, Lipoid - classification | Nephrotic Syndrome - classification | Prednisone - therapeutic use | Care and treatment | Demographic aspects | Nephrotic syndrome | Research | Children | Diseases | Pediatrics | Nephrology | Disease management | Kidney diseases | Children & youth | Index Medicus | Abridged Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 12/2011, Volume 80, Issue 12, pp. 1328 - 1338
The mechanism of selective albuminuria in minimal change nephrotic syndrome, in which glomerular capillaries are diffusely covered by effaced podocyte foot... 
glomerular filtration barrier | NADPH oxidase | nephrotic syndrome | podocyte | reactive oxygen species | nephritic syndrome | AMINONUCLEOSIDE NEPHROSIS | GLOMERULAR-BASEMENT-MEMBRANE | PERMEABILITY | SLIT DIAPHRAGM | NEPHRIN | DIABETIC-NEPHROPATHY | MASSIVE PROTEINURIA | FILTRATION BARRIER | UROLOGY & NEPHROLOGY | KIDNEY | PROXIMAL TUBULE | Immunohistochemistry | Immunoprecipitation | Reactive Oxygen Species - metabolism | Humans | Receptors, Fc - metabolism | NADPH Oxidases - metabolism | Podocytes - enzymology | Rats, Inbred Lew | Nephrosis, Lipoid - enzymology | Nephrosis, Lipoid - urine | Male | Green Fluorescent Proteins - genetics | Puromycin | Histocompatibility Antigens Class I - metabolism | Biological Transport | Acetophenones - pharmacology | Nephrosis, Lipoid - drug therapy | Albuminuria - urine | Disease Models, Animal | Albuminuria - pathology | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Microscopy, Electron, Scanning | Rats, Transgenic | Endocytosis - drug effects | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Albuminuria - prevention & control | Rats, Sprague-Dawley | Albuminuria - enzymology | Microscopy, Confocal | Podocytes - ultrastructure | Animals | Nephrosis, Lipoid - pathology | Podocytes - drug effects | Albuminuria - chemically induced | Nephrosis, Lipoid - chemically induced | Kinetics | Oxidative Stress - drug effects | Serum Albumin - metabolism | Index Medicus
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 2015, Volume 10, Issue 4, pp. 592 - 600
Background and objectives Steroid-resistant nephrotic syndrome is a rare kidney disease involving either immune-mediated or genetic alterations of podocyte... 
UROLOGY & NEPHROLOGY | PATTERNS | THERAPY | MUTATIONS | CYCLOPHOSPHAMIDE | NPHS2 | Recurrence | Age Distribution | Prospective Studies | Glomerulosclerosis, Focal Segmental - genetics | Humans | Immunosuppressive Agents - therapeutic use | Nephrosis, Lipoid - epidemiology | Child, Preschool | Infant | Male | Nephrotic Syndrome - genetics | Nephrotic Syndrome - congenital | Young Adult | DNA Mutational Analysis | Female | Registries | Nephrotic Syndrome - therapy | Retrospective Studies | Child | Nephrotic Syndrome - diagnosis | Infant, Newborn | Latin America - epidemiology | Genetic Predisposition to Disease | Nephrosis, Lipoid - diagnosis | Glomerulosclerosis, Focal Segmental - epidemiology | Risk Factors | Europe - epidemiology | Treatment Outcome | Kidney Transplantation | Nephrosis, Lipoid - therapy | Genetic Markers | Nephrosis, Lipoid - genetics | Glomerulonephritis, Membranoproliferative - therapy | Remission Induction | Glomerulosclerosis, Focal Segmental - diagnosis | Glomerulonephritis, Membranoproliferative - genetics | Middle East - epidemiology | Phenotype | Biopsy | Adolescent | Age of Onset | Nephrotic Syndrome - epidemiology | Glomerulonephritis, Membranoproliferative - diagnosis | Glomerulosclerosis, Focal Segmental - therapy | Mutation | Glomerulonephritis, Membranoproliferative - epidemiology | Index Medicus | podocytopathies | nephrin | children | WT1 | Original | podocin
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 04/2013, Volume 83, Issue 4, pp. 749 - 756
The Nephrotic Syndrome Study Network (NEPTUNE) is a North American multicenter collaborative consortium established to develop a translational research... 
clinical trial | focal segmental glomerulosclerosis | membranous nephropathy | nephrotic syndrome | CLINICAL SPECTRUM | BIOLOGY | UROLOGY & NEPHROLOGY | GENETIC-HETEROGENEITY | CLASSIFICATION | RENAL-DISEASE | IDIOPATHIC MEMBRANOUS NEPHROPATHY | Predictive Value of Tests | Glomerulonephritis - therapy | Prognosis | Prospective Studies | Age Factors | Glomerulosclerosis, Focal Segmental - genetics | Humans | Nephrosis, Lipoid - epidemiology | Glomerulonephritis, Membranous - genetics | Glomerulonephritis, Membranous - epidemiology | Nephrotic Syndrome - genetics | Systems Biology | Time Factors | Adult | Registries | Surveys and Questionnaires | Nephrotic Syndrome - therapy | Translational Medical Research - methods | Child | Glomerulonephritis, Membranous - therapy | Glomerulonephritis - epidemiology | Glomerulosclerosis, Focal Segmental - epidemiology | Glomerulonephritis, Membranous - pathology | Risk Factors | Glomerulonephritis - genetics | Cooperative Behavior | Nephrotic Syndrome - pathology | Genotype | Nephrosis, Lipoid - therapy | Nephrosis, Lipoid - genetics | Phenotype | Pilot Projects | Nephrosis, Lipoid - pathology | Biopsy | Glomerulonephritis - pathology | Nephrotic Syndrome - epidemiology | Glomerulosclerosis, Focal Segmental - therapy | North America - epidemiology | Longitudinal Studies | Research Design | Glomerulosclerosis, Focal Segmental - pathology | Index Medicus
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 2017, Volume 12, Issue 4, pp. 614 - 623
Background and objectives Large-scale, contemporary studies exploring glomerular disease epidemiology in the United States are lacking. We aimed to determine... 
Glomerulonephritis | Demography | Humans | Middle Aged | Hispanic Americans | African Americans | Antibodies | Male | Lupus nephritis | Nephrosis | Histopathology | Renal biopsy | Glomerular disease | Adult | Lipoid | Cross-Sectional Studies | Diabetic Nephropathies | MeSH Browser: Southeastern United States Southeastern United States | European Continental Ancestry Group | Environmental Exposure | Clinical epidemiology | Biopsy | Aged | Antineutrophil Cytoplasmic | Kidney Glomerulus | GLOMERULONEPHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | CHANGING INCIDENCE | ADULTS | UROLOGY & NEPHROLOGY | IGA NEPHROPATHY | CLASSIFICATION | PREVALENCE | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | RENAL BIOPSY | Nephrosis, Lipoid - epidemiology | Child, Preschool | Infant | Glomerulonephritis, Membranous - epidemiology | Incidence | Young Adult | Time Factors | Female | Lupus Nephritis - epidemiology | Child | Glomerulonephritis, IGA - epidemiology | Glomerulonephritis - epidemiology | Glomerulonephritis, IGA - pathology | Lupus Nephritis - pathology | Glomerulonephritis, Membranoproliferative - pathology | Diabetic Nephropathies - pathology | Glomerulosclerosis, Focal Segmental - epidemiology | Glomerulonephritis, Membranous - pathology | Southeastern United States - epidemiology | Kidney Glomerulus - pathology | Nephrosis, Lipoid - pathology | Glomerulonephritis - pathology | Adolescent | Diabetic Nephropathies - epidemiology | Glomerulonephritis, Membranoproliferative - epidemiology | Glomerulosclerosis, Focal Segmental - pathology | Index Medicus | renal biopsy | histopathology | glomerular disease | Antibodies, Antineutrophil Cytoplasmic | clinical epidemiology | lupus nephritis | Nephrosis, Lipoid | glomerulonephritis | Original
Journal Article
Nephrology, ISSN 1320-5358, 09/2016, Volume 21, Issue 9, pp. 765 - 773
LMX1B mutations known to cause nail‐patella syndrome were recently identified in patients with nail‐patella‐like disease and in patients with herediary FSGS... 
LMX1B | autosomal dominant | nail‐patella syndrome | podocin | whole exome sequencing | nail-patella syndrome | PROJECT | PHENOTYPE | PODOCYTES | KIDNEYS | ANNOTATION | UROLOGY & NEPHROLOGY | SEGMENTAL DUPLICATIONS | SEQUENCING DATA | HUMAN-GENOME | EXPRESSION | Kidney - pathology | Glomerulosclerosis, Focal Segmental - genetics | Humans | Child, Preschool | Infant | Male | Proteinuria - pathology | Young Adult | Kidney - metabolism | Time Factors | DNA Mutational Analysis | Kidney Failure, Chronic - pathology | Adult | Female | Child | Kidney - physiopathology | Nephrosis, Lipoid - metabolism | Kidney Failure, Chronic - physiopathology | Genetic Predisposition to Disease | Nephrosis - pathology | Genetic Markers | Nephrosis - genetics | Proteinuria - genetics | Transcription Factors - genetics | Nephrosis, Lipoid - genetics | Disease Progression | Glomerulosclerosis, Focal Segmental - metabolism | Proteinuria - physiopathology | Kidney Failure, Chronic - genetics | Collagen - metabolism | LIM-Homeodomain Proteins - genetics | Phenotype | Nephrosis - physiopathology | Nephrosis, Lipoid - pathology | Biopsy | Pedigree | Adolescent | Fluorescent Antibody Technique | Heterozygote | Mutation | Glomerulosclerosis, Focal Segmental - pathology | Medical research | Chronic kidney failure | Collagen | Genetic research | Medicine, Experimental | Development and progression | Genetic aspects | Index Medicus
Journal Article
Journal Article