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1. Full Text Consensus guidelines for the management and treatment of neuroendocrine tumors
by Kunz, Pamela L and Reidy-Lagunes, Diane and Anthony, Lowell B and Bertino, Erin M and Brendtro, Kari and Chan, Jennifer A and Chen, Herbert and Jensen, Robert T and Kim, Michelle Kang and Klimstra, David S and Kulke, Matthew H and Liu, Eric H and Metz, David C and Phan, Alexandria T and Sippel, Rebecca S and Strosberg, Jonathan R and Yao, James C and North American Neuroendocrine Tumor Society
Pancreas, ISSN 0885-3177, 05/2013, Volume 42, Issue 4, pp. 557 - 577
Neuroendocrine tumors are a heterogeneous group of tumors originating in various anatomic locations. The management of this disease poses a significant... 
pheochromocytoma | neuroendocrine/diagnosis | neuroendocrine/pathology | carcinoid | neuroendocrine/treatment | neuroendocrine tumors | SURVIVAL | DIAGNOSIS | HEPATIC METASTASES | EVEROLIMUS | CARCINOMAS | GASTROENTEROLOGY & HEPATOLOGY | Neuroendocrine Tumors - pathology | Societies, Medical | Neuroendocrine Tumors - metabolism | Humans | Biomarkers, Tumor - metabolism | Neuroendocrine Tumors - therapy | Molecular Targeted Therapy | North America | treatment | neuroendocrine | pathology | diagnosis | Neuroendocrine tumors
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2. Full Text A Practical Approach to the Classification of WHO Grade 3 (G3) Well-differentiated Neuroendocrine Tumor (WD-NET) and Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) of the Pancreas
by Tang, Laura H and Basturk, Olca and Sue, Jillian J and Klimstra, David S
The American Journal of Surgical Pathology, ISSN 0147-5185, 06/2016, Volume 40, Issue 9, pp. 1192 - 1202
High-grade neuroendocrine neoplasms (World Health Organization [WHO] G3) of the pancreas include both well-differentiated neuroendocrine tumor (WD-NET) and... 
neuroendocrine carcinoma | neuroendocrine tumor | high grade | pancreas | WHO G3 | SURVIVAL | SYSTEM | SURGERY | PROGNOSTIC-FACTORS | NEOPLASMS | GASTROINTESTINAL-TRACT | DISTINCT | ENDOCRINE TUMORS | PATHOLOGY | PATHWAY | SMALL-CELL | Immunohistochemistry | Neuroendocrine Tumors - pathology | Carcinoma, Neuroendocrine - mortality | Biomarkers, Tumor - analysis | Carcinoma, Neuroendocrine - classification | Humans | Middle Aged | Pancreatic Neoplasms - pathology | Male | Young Adult | Disease-Free Survival | Neoplasm Grading | Neuroendocrine Tumors - classification | Carcinoma, Neuroendocrine - pathology | Adolescent | Neuroendocrine Tumors - mortality | Survival Analysis | Aged, 80 and over | Pancreatic Neoplasms - classification | Adult | Female | Aged | Cell Differentiation | Pancreatic Neoplasms - mortality | Pancreas | Neuroendocrine tumor | Neuroendocrine carcinoma | High grade
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3. Full Text ENETS Consensus Guidelines for High-Grade Gastroenteropancreatic Neuroendocrine Tumors and Neuroendocrine Carcinomas
by Garcia-Carbonero, R and Sorbye, H and Baudin, E and Raymond, E and Wiedenmann, B and Niederle, B and Sedlackova, E and Toumpanakis, C and Anlauf, M and Cwikla, J.B and Caplin, M and O''Toole, D and Perren, A and Vienna Consensus Conference and Vienna Consensus Conference participants and all other Vienna Consensus Conference participants
Neuroendocrinology, ISSN 0028-3835, 04/2016, Volume 103, Issue 2, pp. 186 - 194
ENETS Consensus Guidelines | CELL LUNG-CANCER | PHASE-III TRIAL | ETOPOSIDE | PROGNOSTIC-FACTORS | CISPLATIN | NEOPLASMS | NEURON-SPECIFIC ENOLASE | ENDOCRINOLOGY & METABOLISM | PANCREAS | CHROMOGRANIN-A | NEUROSCIENCES | CHEMOTHERAPY | Stomach Neoplasms - genetics | Carcinoma, Neuroendocrine - diagnosis | Pancreatic Neoplasms - epidemiology | Stomach Neoplasms - diagnosis | Pancreatic Neoplasms - diagnosis | Humans | Stomach Neoplasms - therapy | Carcinoma, Neuroendocrine - epidemiology | Carcinoma, Neuroendocrine - therapy | Carcinoma, Neuroendocrine - genetics | Pancreatic Neoplasms - genetics | Intestinal Neoplasms - epidemiology | Neuroendocrine Tumors - diagnosis | Neuroendocrine Tumors - epidemiology | Neuroendocrine Tumors - genetics | Intestinal Neoplasms - therapy | Stomach Neoplasms - epidemiology | Neuroendocrine Tumors - therapy | Intestinal Neoplasms - diagnosis | Intestinal Neoplasms - genetics | Pancreatic Neoplasms - therapy
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4. Full Text Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
by Janson, Eva Tiensuu and Sorbye, Halfdan and Welin, Staffan and Federspiel, Birgitte and Grønbæk, Henning and Hellman, Per and Ladekarl, Morten and Langer, Seppo W and Mortensen, Jann and Schalin-Jäntti, Camilla and Sundin, Anders and Sundlöv, Anna and Thiis-Evensen, Espen and Knigge, Ulrich and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Enheten för radiologi and Onkologisk endokrinologi and Institutionen för radiologi, onkologi och strålningsvetenskap and Uppsala universitet and Institutionen för medicinska vetenskaper and Endokrinkirurgi and Institutionen för kirurgiska vetenskaper
Acta Oncologica, ISSN 0284-186X, 10/2014, Volume 53, Issue 10, pp. 1284 - 1297
Abstract Background. The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods... 
RADIOLABELED SOMATOSTATIN ANALOG | LIVER METASTASES | INTERFERON-ALPHA | GEP-NETS | HEPATIC METASTASES | PROGNOSTIC-FACTORS | ONCOLOGY | SMALL-CELL CARCINOMA | ENDOCRINE TUMORS | CHROMOGRANIN-A | Y-90 MICROSPHERES | Carcinoma, Neuroendocrine - diagnosis | Pancreatic Neoplasms - chemistry | Gastrointestinal Neoplasms - genetics | Prognosis | Neuroendocrine Tumors - chemistry | Pancreatic Neoplasms - diagnosis | Humans | Carcinoma, Neuroendocrine - therapy | Antineoplastic Agents - therapeutic use | Liver Neoplasms - therapy | Neuroendocrine Tumors - diagnosis | Diagnostic Imaging - methods | Gastrointestinal Neoplasms - pathology | Carcinoma, Neuroendocrine - chemistry | Liver Neoplasms - secondary | Neuroendocrine Tumors - pathology | Biomarkers, Tumor - analysis | Pancreatic Neoplasms - pathology | Carcinoma, Neuroendocrine - genetics | Pancreatic Neoplasms - genetics | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Neuroendocrine Tumors - genetics | Gastrointestinal Neoplasms - chemistry | Liver Neoplasms - diagnosis | Carcinoma, Neuroendocrine - pathology | Neuroendocrine Tumors - therapy | Pancreatic Neoplasms - therapy | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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5. Full Text Grading of Well-differentiated Pancreatic Neuroendocrine Tumors Is Improved by the Inclusion of Both Ki67 Proliferative Index and Mitotic Rate
by McCall, Chad M and Shi, Chanjuan and Cornish, Toby C and Klimstra, David S and Tang, Laura H and Basturk, Olca and Mun, Liew Jun and Ellison, Trevor A and Wolfgang, Christopher L and Choti, Michael A and Schulick, Richard D and Edil, Barish H and Hruban, Ralph H
The American Journal of Surgical Pathology, ISSN 0147-5185, 11/2013, Volume 37, Issue 11, pp. 1671 - 1677
The grading system for pancreatic neuroendocrine tumors (PanNETs) adopted in 2010 by the World Health Organization (WHO) mandates the use of both mitotic rate... 
gastroenteropancreatic neuroendocrine tumor | pancreatic endocrine neoplasm islet cell tumor | pancreatic cancer | pancreas | pancreatic neuroendocrine tumor | endocrine neoplasm | neuroendocrine tumor | Ki67 | SYSTEM | SURGERY | NEOPLASMS | ENDOCRINE TUMORS | MARKERS | PATHOLOGY | BREAST-CANCER | HETEROGENEITY | KI-67 | islet cell tumor | COUNT | pancreatic endocrine neoplasm | Immunohistochemistry | Predictive Value of Tests | Pancreatic Neoplasms - chemistry | Cell Proliferation | Prognosis | Neuroendocrine Tumors - chemistry | Humans | Middle Aged | Male | Young Adult | Neoplasm Grading | Aged, 80 and over | Adult | Female | Cell Differentiation | Pancreatic Neoplasms - mortality | Neuroendocrine Tumors - pathology | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - surgery | Kaplan-Meier Estimate | Proportional Hazards Models | Mitotic Index | Ki-67 Antigen - analysis | Biopsy | Neuroendocrine Tumors - secondary | Adolescent | Neuroendocrine Tumors - mortality | Neuroendocrine Tumors - surgery | Aged
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6. Full Text Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas
by Oronsky, Bryan and Ma, Patrick C and Morgensztern, Daniel and Carter, Corey A
Neoplasia, ISSN 1476-5586, 12/2017, Volume 19, Issue 12, pp. 991 - 1002
This review covers the diverse topic of neuroendocrine neoplasms (NENs), a relatively rare and heterogeneous tumor type, comprising ~2% of all malignancies,... 
CELL LUNG-CANCER | CONSENSUS GUIDELINES | SOMATOSTATIN ANALOGS | INTERFERON-ALPHA | PROGNOSTIC-FACTORS | ONCOLOGY | CLINICAL PRESENTATION | GASTROINTESTINAL-TRACT | RECEPTOR RADIONUCLIDE THERAPY | SYSTEMIC THERAPY | VALVE DISEASE | Carcinoma, Neuroendocrine - diagnosis | Disease Susceptibility | Carcinoma, Neuroendocrine - etiology | Humans | Carcinoma, Neuroendocrine - epidemiology | Carcinoma, Neuroendocrine - therapy | Neuroendocrine Tumors - diagnosis | Neuroendocrine Tumors - epidemiology | Biomarkers, Tumor | Algorithms | Animals | Neoplasm Grading | Disease Management | Neuroendocrine Tumors - therapy | Neuroendocrine Tumors - etiology | Neoplasm Staging
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7. Full Text Exploring the rising incidence of neuroendocrine tumors: A population‐based analysis of epidemiology, metastatic presentation, and outcomes
by Hallet, Julie and Law, Calvin How Lim and Cukier, Moises and Saskin, Refik and Liu, Ning and Singh, Simron
Cancer, ISSN 0008-543X, 02/2015, Volume 121, Issue 4, pp. 589 - 597
BACKGROUND An increased incidence of neuroendocrine tumors (NETs) has been reported worldwide, but the reasons underlying this rise have not been identified.... 
epidemiology | detection | neuroendocrine | carcinoid | incidence | Carcinoid | Detection | Neuroendocrine | Epidemiology | Incidence | ONCOLOGY | CARCINOID-TUMORS | RISK | CANCER | TRENDS | Neuroendocrine Tumors - pathology | Rural Population - statistics & numerical data | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Male | Treatment Outcome | Neuroendocrine Tumors - epidemiology | Neuroendocrine Tumors - mortality | Ontario - epidemiology | Adult | Female | Aged | Neuroendocrine Tumors - therapy | Retrospective Studies | Odds Ratio | Databases, Factual | Poverty - statistics & numerical data | Treatment outcome | Research | Analysis
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8. Full Text NET Blood Transcript Analysis Defines the Crossing of the Clinical Rubicon: When Stable Disease Becomes Progressive
by Pavel, Marianne and Jann, Henning and Prasad, Vikas and Drozdov, Ignat and Modlin, Irvin M and Kidd, Mark
Neuroendocrinology, ISSN 0028-3835, 12/2016, Volume 104, Issue 2, pp. 170 - 182
Background/Aims: A key issue in gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is early identification and prediction of disease progression. Clinical... 
Multianalyte | Polymerase chain reaction | Transcript | Biomarker | Chromogranin | NETest | Carcinoids | Neuroendocrine tumor | Prognostic | SURVIVAL | NEUROENDOCRINE TUMORS | MANAGEMENT | NEOPLASMS | ENETS CONSENSUS GUIDELINES | CHROMOGRANIN-A | NEUROSCIENCES | HEPATIC METASTASES | ENDOCRINOLOGY & METABOLISM | HALLMARKS | CORRELATE | Neuroendocrine Tumors - blood | Gastrointestinal Neoplasms - genetics | Follow-Up Studies | Pancreatic Neoplasms - diagnosis | Humans | Middle Aged | Male | Neuroendocrine Tumors - diagnosis | Gastrointestinal Neoplasms - pathology | Neoplasm Grading | Gastrointestinal Neoplasms - blood | Aged, 80 and over | Adult | Female | Real-Time Polymerase Chain Reaction | Neuroendocrine Tumors - pathology | Pancreatic Neoplasms - blood | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Gastrointestinal Neoplasms - diagnosis | Disease Progression | Neuroendocrine Tumors - genetics | Biomarkers, Tumor - blood | Disease-Free Survival | Aged | Biomarkers, Tumor - genetics
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9. Full Text Recent updates on neuroendocrine tumors from the gastrointestinal and pancreatobiliary tracts
by Kim, Joo Young and Hong, Seung-Mo
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 05/2016, Volume 140, Issue 5, pp. 437 - 448
Context.-Gastrointestinal (GI) and pancreatobiliary tracts contain a variety of neuroendocrine cells that constitute a diffuse endocrine system. Neuroendocrine... 
GANGLIOCYTIC PARAGANGLIOMA | MEDICINE, RESEARCH & EXPERIMENTAL | KI67 PROLIFERATIVE INDEX | RECTAL NEUROENDOCRINE | GASTROENTEROPANCREATIC SYSTEM | PATHOLOGY | ENDOCRINE NEOPLASIA TYPE-1 | PATHOLOGICAL CLASSIFICATION | LYMPH-NODE METASTASIS | IMMUNOHISTOCHEMICAL ANALYSIS | GOBLET-CELL CARCINOIDS | PROGNOSTIC-SIGNIFICANCE | MEDICAL LABORATORY TECHNOLOGY | Education, Medical, Continuing | Carcinoma, Neuroendocrine - diagnosis | Pancreatic Neoplasms - metabolism | Prognosis | Pancreatic Neoplasms - diagnosis | Humans | Neuroendocrine Tumors - diagnosis | Gastrointestinal Tract - pathology | Gastrointestinal Neoplasms - pathology | Mixed Tumor, Malignant - pathology | Neoplasm Grading | Biliary Tract - metabolism | Pathology, Clinical - manpower | Biliary Tract Neoplasms - metabolism | Biomarkers, Tumor - metabolism | Neuroendocrine Cells - metabolism | Mixed Tumor, Malignant - metabolism | Biliary Tract Neoplasms - pathology | Gastrointestinal Neoplasms - metabolism | Carcinoma, Neuroendocrine - metabolism | Neuroendocrine Tumors - pathology | Diagnosis, Differential | Neuroendocrine Cells - pathology | World Health Organization | Neuroendocrine Tumors - metabolism | Mixed Tumor, Malignant - diagnosis | Pancreatic Neoplasms - pathology | Pancreas - pathology | Gastrointestinal Neoplasms - diagnosis | Pancreas - metabolism | Biliary Tract Neoplasms - diagnosis | Gastrointestinal Tract - metabolism | Biliary Tract - pathology | Mitotic Index | Pathology, Clinical - methods | Carcinoma, Neuroendocrine - pathology | Pathology, Clinical - trends | Pathology, Clinical - education | Neoplasm Staging | Practice Guidelines as Topic | Tuberous sclerosis | Cancer
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10. Full Text The clinicopathologic heterogeneity of grade 3 gastroenteropancreatic neuroendocrine neoplasms: Morphological differentiation and proliferation identify different prognostic categories
by Milione, Massimo and Maisonneuve, Patrick and Spada, Francesca and Pellegrinelli, Alessio and Spaggiari, Paola and Albarello, Luca and Pisa, Eleonora and Barberis, Massimo and Vanoli, Alessandro and Buzzoni, Roberto and Pusceddu, Sara and Concas, Laura and Sessa, Fausto and Solcia, Enrico and Capella, Carlo and Fazio, Nicola and La Rosa, Stefano
Neuroendocrinology, ISSN 0028-3835, 11/2016, Volume 104, Issue 1, pp. 85 - 93
Background/Aims: Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are defined as neuroendocrine neoplasms (NENs) with a Ki-67 index > 20%... 
Prognosis | Proliferation | Morphology | Neuroendocrine carcinoma | Classification | SYSTEM | WELL | ENDOCRINOLOGY & METABOLISM | CARCINOMAS | G3 | TUMORS | NEUROSCIENCES | Neuroendocrine Tumors - pathology | Carcinoma, Neuroendocrine - mortality | Cell Proliferation | Carcinoma, Neuroendocrine - drug therapy | Humans | Pancreatic Neoplasms - pathology | Ki-67 Antigen - metabolism | Male | Antineoplastic Agents - therapeutic use | Proto-Oncogene Proteins c-kit - metabolism | Pancreatic Neoplasms - drug therapy | Regression Analysis | Ion Channels - metabolism | Carcinoma, Neuroendocrine - pathology | Neuroendocrine Tumors - mortality | Survival Analysis | Neuroendocrine Tumors - drug therapy | Female | Cell Differentiation | Pancreatic Neoplasms - mortality
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11. Full Text Molecular profiling of neuroendocrine malignancies to identify prognostic and therapeutic markers: A Fox Chase Cancer Center Pilot Study
by Vijayvergia, Namrata and Boland, Patrick M and Handorf, Elizabeth and Gustafson, Karen S and Gong, Yulan and Cooper, Harry S and Sheriff, Fathima and Astsaturov, Igor and Cohen, Steven J and Engstrom, Paul F
British Journal of Cancer, ISSN 0007-0920, 08/2016, Volume 115, Issue 5, pp. 564 - 570
Background: The rarity of neuroendocrine malignancies limits the ability to develop new therapies and thus a better understanding of the underlying biology is... 
neuroendocrine tumours; molecular profiling; next-generation sequencing; genomic landscape; targeted therapy; neuroendocrine carcinoma; neuroendocrine malignancies | genomic landscape | targeted therapy | NANETS CONSENSUS GUIDELINES | MANAGEMENT | EVEROLIMUS | next-generation sequencing | neuroendocrine carcinoma | neuroendocrine malignancies | TUMORS | CAPECITABINE | HIGH-GRADE | ONCOLOGY | CARCINOMAS | neuroendocrine tumours | MUTATIONS | SMALL-CELL | EPIDEMIOLOGY | molecular profiling | Neuroendocrine Tumors - pathology | Prognosis | Humans | Middle Aged | Male | Gene Expression Profiling | Neuroendocrine Tumors - genetics | Pilot Projects | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Aged | Molecular Diagnostics
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12. Full Text Neuroendocrine tumor disease: An evolving landscape
by Frilling, Andrea and Åkerström, Goran and Falconi, Massimo and Pavel, Marianne and Ramos, Jose and Kidd, Mark and Modlin, Irvin Mark and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Endokrinkirurgi and Institutionen för kirurgiska vetenskaper
Endocrine-Related Cancer, ISSN 1351-0088, 10/2012, Volume 19, Issue 5, pp. R163 - R185
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) represent a heterogenous group of tumors arising from a variety of neuroendocrine cell types. The... 
RADIOLABELED SOMATOSTATIN ANALOG | NEOPLASIA TYPE-1 | SINGLE-CENTER EXPERIENCE | PANCREATIC ENDOCRINE TUMORS | LIVER-TRANSPLANTATION | ONCOLOGY | ENETS CONSENSUS GUIDELINES | MIDGUT CARCINOID-TUMORS | ENDOCRINOLOGY & METABOLISM | ISLET-CELL TUMORS | CHROMOGRANIN-A | ZOLLINGER-ELLISON-SYNDROME | Pancreatic Neoplasms - epidemiology | Pancreatic Neoplasms - metabolism | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - diagnosis | Humans | Antineoplastic Agents - therapeutic use | Neuroendocrine Tumors - diagnosis | Neuroendocrine Tumors - epidemiology | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Gastrointestinal Neoplasms - epidemiology | Biomarkers, Tumor - metabolism | Neuroendocrine Tumors - therapy | Gastrointestinal Neoplasms - metabolism | Pancreatic Neoplasms - therapy | dalotuzumab | temozolomide | Ki 67 antigen | Medical and Health Sciences | sorafenib | cancer surgery | antiproliferative activity | capecitabine | thalidomide | review | bevacizumab | cyclophosphamide | neuroendocrine tumor | protein expression | sunitinib | glucagonoma | liver metastasis | midgut neuroendocrine tumor | imatinib | cancer diagnosis | gefitinib | 5 hydroxyindoleacetic acid | vasculotropin antibody | somatostatin derivative | motesanib | cancer epidemiology | insulinoma | octreotide | gastrinoma | molecularly targeted therapy | Medicin och hälsovetenskap | pasireotide | tumor ablation | cancer grading | angiopeptin | delayed diagnosis | everolimus | gastric neuroendocrine tumor | human | vipoma | cancer combination chemotherapy | somatostatin receptor | gastroenteropancreatic neuroendocrine neoplasm | cancer localization | pazopanib | cancer prognosis | streptozocin | temsirolimus | pancreatic neuroendocrine tumor | treatment response | chromogranin A | drug efficacy | positron emission tomography | cancer incidence | lymph node metastasis
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