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Prostaglandins, leukotrienes and essential fatty acids, ISSN 0952-3278, 2010, Volume 82, Issue 1, pp. 27 - 34
Abstract Retinal pigment epithelial (RPE) cells, derived from the neuroectoderm, biosynthesize the novel lipid mediator neuroprotectin D1 (NPD1... 
Endocrinology & Metabolism | Advanced Basic Science | Binding | Photoreceptors | Inflammation | Mediators | Neuroprotectin | Resolution | SURVIVAL | APOPTOSIS | MEDIATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLVIN-E1 | RECEPTOR | CELL BIOLOGY | ANTIINFLAMMATORY PROPERTIES | PROTECTIN-D1 | DOCOSAHEXAENOIC ACID | ENDOCRINOLOGY & METABOLISM | ASSIGNMENTS | BRAIN | Epoxy Compounds - metabolism | Retinal Pigment Epithelium - metabolism | Apoptosis - drug effects | Antioxidants - metabolism | Eicosapentaenoic Acid - analogs & derivatives | Humans | Isomerism | Neuroprotective Agents - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Neuroprotective Agents - pharmacology | Eicosapentaenoic Acid - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Neutrophils - metabolism | Retinal Pigment Epithelium - drug effects | Binding, Competitive | Hydrogen Peroxide - toxicity | Cell Line | Docosahexaenoic Acids - chemical synthesis | Docosahexaenoic Acids - chemistry | Neutrophils - drug effects | Eicosapentaenoic Acid - metabolism | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Tumor Necrosis Factor-alpha - toxicity | Docosahexaenoic Acids - pharmacology | Neuroprotective Agents - chemical synthesis | Epoxy Compounds - chemistry | Kinetics | Oxidative Stress - drug effects | Lipoxins - metabolism | Docosahexaenoic Acids - metabolism | Unsaturated fatty acids | Animal pigments | Chemical properties | Analgesics | Omega-3 fatty acids
Journal Article
Experimental neurology, ISSN 0014-4886, 2012, Volume 236, Issue 1, pp. 122 - 130
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 36, pp. 6818 - 6823
Protectin D1 is a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models... 
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 2014, Volume 12, Issue 3, pp. 432 - 437
Journal Article
Journal Article
Tetrahedron letters, ISSN 0040-4039, 04/2012, Volume 53, Issue 14, pp. 1695 - 1698
Neuroprotectin D1/Protectin D1, a potent anti-inflammatory, proresolving, and neuroprotective lipid mediator derived biosynthetically from docosahexaenoic acid, was prepared in an enantiomerically... 
Neuroprotectin D1/protectin D1 | Aspirin | Docosahexaenoic acid | Anti-inflammatory | Total synthesis | DOCOSATRIENES | PIGMENT EPITHELIAL-CELLS | INFLAMMATION | CHEMISTRY, ORGANIC | BRAIN | Unsaturated fatty acids | Synthesis | Analgesics | Chemical synthesis | Fatty acids | Omega-3 fatty acids | Organic compounds | Synthesis (chemistry) | Precursors | Olefins | Isomerization | Lipids | Strategy | Alkynes | Protectin D1 | Neuroprotectin D1
Journal Article
Molecular medicine reports, ISSN 1791-2997, 08/2013, Volume 8, Issue 2, pp. 543 - 550
Neuroprotectin D1 (NPD1) may serve an endogenous neuroprotective role in brain ischemic injury, yet the underlying mechanism involved is poorly understood... 
Neuroprotection | CREB | Neuroprotectin D1 | Rat | Middle cerebral artery occlusion | TrpC | MEDICINE, RESEARCH & EXPERIMENTAL | rat | MECHANISMS | PROTEOLYSIS | neuroprotectin D1 | CELL-DEATH | STROKE | TRPC CHANNELS | ISCHEMIC-INJURY | ONCOLOGY | neuroprotection | DOCOSAHEXAENOIC ACID | GROWTH | DEGRADATION | middle cerebral artery occlusion
Journal Article
Biochimie, ISSN 0300-9084, 04/2014, Volume 99, Issue 1, pp. 1 - 7
.... Among them, protectin D1 (PD1), an endogenous dihydroxylated and non-cyclic docosatriene made through lipoxygenation and hydrolysis of an epoxide intermediate, shows appealing biological effects... 
Protectin | Inflammation | Maresin | Docosatrienes | PUFA metabolites | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | LIPID MEDIATORS | OMEGA-3-DERIVED MEDIATORS | NEUROPROTECTIN D1 | RESOLVINS | DOCOSAHEXAENOIC ACID | POLYUNSATURATED FATTY-ACIDS | HUMAN BLOOD | Animals | Hydroxylation | Docosahexaenoic Acids - physiology | Stereoisomerism | Humans | Hydrolysis | Unsaturated fatty acids | Metabolites | Diastereomers | Omega-3 fatty acids | Organic chemistry | Chemical Sciences
Journal Article