X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
neuroserpin (198) 198
humans (103) 103
index medicus (103) 103
animals (95) 95
neurosciences (64) 64
serpins - metabolism (61) 61
serpins - genetics (52) 52
neuropeptides - metabolism (50) 50
biochemistry & molecular biology (47) 47
mice (42) 42
neuropeptides - genetics (42) 42
tissue-plasminogen activator (39) 39
expression (37) 37
neurons (37) 37
tissue plasminogen activator (34) 34
male (32) 32
serpins - chemistry (32) 32
mutation (30) 30
serpin (30) 30
brain (29) 29
rats (29) 29
dementia (28) 28
proteins (28) 28
polymerization (27) 27
tissue plasminogen activator - metabolism (26) 26
cell biology (25) 25
female (25) 25
familial encephalopathy (24) 24
neuroserpin inclusion-bodies (23) 23
brain - metabolism (22) 22
inhibitor (22) 22
conformational disease (21) 21
ischemia (21) 21
neuropeptides - chemistry (21) 21
protein conformation (21) 21
serpins (21) 21
stroke (21) 21
amino acid sequence (20) 20
analysis (20) 20
cells, cultured (20) 20
forms polymers (20) 20
protease inhibitors (20) 20
clinical neurology (19) 19
gene expression (19) 19
long-term potentiation (19) 19
multidisciplinary sciences (19) 19
encephalopathy (18) 18
gene (18) 18
models, molecular (18) 18
neurons - metabolism (18) 18
proteinase-inhibitor (18) 18
serine-protease inhibitor (18) 18
molecular sequence data (17) 17
proteases (17) 17
alzheimer's disease (16) 16
crystal-structure (16) 16
protein folding (16) 16
aged (15) 15
middle aged (15) 15
nervous-system (15) 15
neuroprotection (15) 15
protects neurons (15) 15
tissue plasminogen activator - antagonists & inhibitors (15) 15
blood-brain-barrier (14) 14
endoplasmic-reticulum (14) 14
focal cerebral-ischemia (14) 14
immunohistochemistry (14) 14
mechanism (14) 14
nervous system (14) 14
plasminogen-activator (14) 14
receptor-related protein (14) 14
serine proteinase inhibitors - metabolism (14) 14
alpha-antitrypsin (13) 13
alzheimers-disease (13) 13
antitrypsin (13) 13
polymers (13) 13
proteolysis (13) 13
research article (13) 13
serine (13) 13
serpins - pharmacology (13) 13
thrombin (13) 13
tpa (13) 13
apoptosis (12) 12
brain - pathology (12) 12
central-nervous-system (12) 12
disease models, animal (12) 12
endoplasmic reticulum (12) 12
genetic aspects (12) 12
genetics & heredity (12) 12
in-vitro (12) 12
mice lacking (12) 12
mice, inbred c57bl (12) 12
neurons - drug effects (12) 12
neuroscience (12) 12
plasminogen-activator inhibitor-1 (12) 12
research (12) 12
serine proteinase (12) 12
t-plasminogen activator (12) 12
accumulation (11) 11
fenib (11) 11
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Neurobiology of Disease, ISSN 0969-9961, 2017, Volume 103, pp. 32 - 44
Abstract The serpinopathies are human pathologies caused by mutations that promote polymerisation and intracellular deposition of proteins of the serpin... 
Neurology | Oxidative stress | Neurodegeneration | Neurons | Familial encephalopathy with neuroserpin inclusion bodies | Neural progenitor cells | Neuroserpin | Protein conformational disease | Serpin polymers | HUMAN BRAIN | PROTEIN | NEUROSCIENCES | ENCEPHALOPATHY | GENE | GLUTATHIONE | PATHWAY | DISEASE | DEGRADATION | ACCUMULATION | ASSOCIATION | Neurons - pathology | Heredodegenerative Disorders, Nervous System - pathology | Humans | Oxidative Stress - physiology | Cerebral Cortex - pathology | Epilepsies, Myoclonic - metabolism | Epilepsies, Myoclonic - pathology | Cerebral Cortex - metabolism | Dementia - metabolism | Neuropeptides - toxicity | Neurons - metabolism | Cerebral Cortex - drug effects | Neurons - drug effects | Cell Survival - physiology | Cell Survival - drug effects | Dementia - pathology | Cells, Cultured | Mice, Transgenic | Epilepsies, Myoclonic - chemically induced | Animals | Dementia - chemically induced | Serpins - toxicity | Polymers - toxicity | Mice | Heredodegenerative Disorders, Nervous System - chemically induced | Heredodegenerative Disorders, Nervous System - metabolism | Oxidative Stress - drug effects | Proteins | RNA sequencing | Fluorescence | Genetic engineering | Polymer industry | Dementia | Analysis | Index Medicus | NFκB, nuclear factor κB | A1AT, alpha1 antitrypsin | unfolded protein response, UPR | Aldh, aldehyde dehydrogenase | Prdx6, peroxiredoxin 6 | NS, neuroserpin | FENIB, familial encephalopathy with neuroserpin inclusion bodies | SOD, superoxide dismutase | HRP, horseradish peroxidase | GPx, glutathione peroxidase | wild type, WT | GST, glutathione transferase | ER, endoplasmic reticulum | MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide | ApoE, apolipoprotein E | Scara, scavenger receptor class A
Journal Article
Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 02/2016, Volume 75, Issue 2, pp. 121 - 133
Journal Article
Journal Article
Cardiovascular and Hematological Disorders - Drug Targets, ISSN 1871-529X, 2013, Volume 13, Issue 2, pp. 123 - 132
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0123932
Journal Article
Cellular physiology and biochemistry, ISSN 1421-9778, 2016, Volume 38, Issue 4, pp. 1472 - 1482
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2016, Volume 65, Issue 2, pp. 413 - 424
Journal Article