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1. Boron and gadolinium neutron capture therapy for cancer treatment
by Hosmane, Narayan S
2012, ISBN 9789814338677, xxiii, 246
Boron-neutron capture therapy | Boron Neutron Capture Therapy | methods | radiotherapy | Gadolinium-neutron capture therapy | Gadolinium | therapeutic use | Neoplasms
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2. Full Text Tetrakis(p-Carboranylthio-Tetrafluorophenyl)Chlorin (TPFC): Application for Photodynamic Therapy and Boron Neutron Capture Therapy
by Hiramatsu, Ryo and Kawabata, Shinji and Tanaka, Hiroki and Sakurai, Yoshinori and Suzuki, Minoru and Ono, Koji and Miyatake, Shin-Ichi and Kuroiwa, Toshihiko and Hao, Erhong and Vicente, M. Graça H
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2015, Volume 104, Issue 3, pp. 962 - 970
Carboranyl-containing chlorins have emerged as promising dual sensitizers for use in both photodynamic therapy (PDT) and boron neutron capture therapy (BNCT),... 
PDT | BNCT | blood–brain barrier | CED | absorption | cell culture | boron-containing chlorin | CNS | osmotic pumps | TPFC | boron‐containing chlorin | Cell culture | Absorption | Blood-brain barrier | Osmotic pumps | Boron-containing chlorin | blood-brain barrier | CHEMISTRY, MEDICINAL | BRAIN TUMOR-MODELS | PHOTOSENSITIZING PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | P-BORONOPHENYLALANINE | EPIDERMAL-GROWTH-FACTOR | IN-VIVO | MALIGNANT GLIOMAS | PHARMACOLOGY & PHARMACY | L-ASPARTYL CHLORIN-E6 | CONVECTION-ENHANCED DELIVERY | REAL-TIME | Porphyrins - administration & dosage | Phenylalanine - analogs & derivatives | Phenylalanine - pharmacology | Photochemotherapy - methods | Rats, Inbred F344 | Brain Neoplasms - pathology | Male | Porphyrins - pharmacokinetics | Radiation-Sensitizing Agents - pharmacokinetics | Boron Compounds - administration & dosage | Photosensitizing Agents - administration & dosage | Tissue Distribution | Photosensitizing Agents - pharmacology | Radiation-Sensitizing Agents - administration & dosage | Boron Compounds - chemical synthesis | Glioma - pathology | Glioma - therapy | Radiation-Sensitizing Agents - chemical synthesis | Photosensitizing Agents - chemical synthesis | Boron Compounds - pharmacology | Cell Survival - drug effects | Radiation-Sensitizing Agents - pharmacology | Porphyrins - chemical synthesis | Boron Compounds - pharmacokinetics | Porphyrins - pharmacology | Cell Survival - radiation effects | Boron Neutron Capture Therapy - methods | Animals | Brain Neoplasms - therapy | Cell Line, Tumor | Photosensitizing Agents - pharmacokinetics | Microscopy, Fluorescence
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3. Full Text Neutron Capture Therapy
: Principles and Applications
by Sauerwein, Wolfgang A.G and Moss, Raymond and Nakagawa, Yoshinobu and Wittig, Andrea
2012, 1. Aufl., ISBN 3642313337, Volume 9783642313349, 544
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and... 
Boron-neutron capture therapy | Clinical & internal medicine | Fast neutrons | Therapeutic use
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4. Full Text Nanomaterials: Applications in Cancer Imaging and Therapy
by Barreto, José A and O’Malley, William and Kubeil, Manja and Graham, Bim and Stephan, Holger and Spiccia, Leone
Advanced Materials, ISSN 0935-9648, 03/2011, Volume 23, Issue 12, pp. H18 - H40
The application of nanomaterials (NMs) in biomedicine is increasing rapidly and offers excellent prospects for the development of new non‐invasive strategies... 
synthesis | cancer | nanoparticles | imaging | therapy | IRON-OXIDE NANOPARTICLES | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | DRUG-DELIVERY SYSTEM | IN-VIVO EFFICACY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | UP-CONVERSION LUMINESCENCE | COATED MAGNETITE NANOPARTICLES | NEUTRON-CAPTURE THERAPY | HOLLOW GOLD NANOSPHERES | TUMOR VASCULAR-PERMEABILITY | SEMICONDUCTOR QUANTUM RODS | POLYMER HYBRID NANOPARTICLES | Neoplasms - metabolism | Drug Carriers - metabolism | Neoplasms - therapy | Animals | Humans | Nanostructures - chemistry | Molecular Imaging - methods | Neoplasms - blood supply | Neoplasms - pathology | Drug Carriers - chemistry | Therapy | Imaging | Nanomaterials | Diagnosis | Object recognition | Active control | Cancer | Tumors
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5. Full Text Folate-Targeted Therapies for Cancer
by Xia, Wei and Low, Philip S
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2010, Volume 53, Issue 19, pp. 6811 - 6824
VINCA ALKALOID CONJUGATE | GROWTH-FACTOR RECEPTOR | CHEMISTRY, MEDICINAL | RECEPTOR-MEDIATED ENDOCYTOSIS | NEUTRON-CAPTURE THERAPY | IN-VIVO | HUMAN OVARIAN-CARCINOMA | CULTURED KB CELLS | MONOCLONAL-ANTIBODIES | FOLIC-ACID | POSITIVE TUMOR-CELLS | Neoplasms - metabolism | Genetic Therapy | Up-Regulation | Folate Receptors, GPI-Anchored | Humans | Antineoplastic Agents - therapeutic use | Oligoribonucleotides, Antisense - pharmacology | Drug Carriers | Nanoparticles | Radiopharmaceuticals - metabolism | Neoplasms - therapy | Immunotherapy | Antineoplastic Agents - pharmacology | Receptors, Cell Surface - biosynthesis | Oligoribonucleotides, Antisense - therapeutic use | Radiopharmaceuticals - chemistry | Carrier Proteins - biosynthesis | RNA, Small Interfering - pharmacology | Antineoplastic Agents - chemistry | Neoplasms - diagnostic imaging | Oligoribonucleotides, Antisense - chemistry | Animals | Radionuclide Imaging | Folic Acid - metabolism | Ligands
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6. Full Text l -Boronophenylalanine-Mediated Boron Neutron Capture Therapy for Malignant Glioma Progressing After External Beam Radiation Therapy: A Phase I Study
by Kankaanranta, Leena, M.D and Seppälä, Tiina, Ph.D and Koivunoro, Hanna, M.Sci and Välimäki, Petteri, M.Sci and Beule, Annette, M.D and Collan, Juhani, M.D and Kortesniemi, Mika, Ph.D and Uusi-Simola, Jouni, Ph.D and Kotiluoto, Petri, Ph.D and Auterinen, Iiro, M.Sci and Serèn, Tom, Lic.Tech and Paetau, Anders, M.D and Saarilahti, Kauko, M.D and Savolainen, Sauli, Ph.D and Joensuu, Heikki, M.D
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 80, Issue 2, pp. 369 - 376
Purpose To investigate the safety of boronophenylalanine-mediated boron neutron capture therapy (BNCT) in the treatment of malignant gliomas that progress... 
Radiology | Hematology, Oncology and Palliative Medicine | Brain tumor | Boronophenylalanine | Anaplastic astrocytoma | Boron neutron capture therapy | Glioblastoma | CRITERIA | TRIALS | BNCT | GLIOBLASTOMA-MULTIFORME | CANCER | ADJUVANT TEMOZOLOMIDE | BRAIN-TUMORS | BPA | ONCOLOGY | CONCOMITANT | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Astrocytoma - radiotherapy | Boron Neutron Capture Therapy - mortality | Humans | Middle Aged | Brain Neoplasms - pathology | Boron Neutron Capture Therapy - adverse effects | Male | Boron Compounds - administration & dosage | Glioblastoma - radiotherapy | Brain Neoplasms - surgery | Radiation-Sensitizing Agents - therapeutic use | Young Adult | Astrocytoma - pathology | Adult | Female | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Astrocytoma - mortality | Radiotherapy Dosage | Fructose - adverse effects | Radiation-Sensitizing Agents - adverse effects | Disease Progression | Fructose - therapeutic use | Glioblastoma - surgery | Boron Neutron Capture Therapy - methods | Fructose - analogs & derivatives | Maximum Tolerated Dose | Glioblastoma - pathology | Boron Compounds - adverse effects | Aged | Glioblastoma - mortality | Boron Compounds - therapeutic use | Fructose - administration & dosage | Astrocytoma - surgery | Antimitotic agents | Care and treatment | Antineoplastic agents | Gliomas | Boron-neutron capture therapy | Radiation | Boron | Side effects | Glioma | Toxicity | Brain tumors | Surgery | Neutrons | Radiotherapy | Survival | Astrocytoma | Index Medicus | SEMIMETALS | BORON | NERVOUS SYSTEM | NEUTRON CAPTURE THERAPY | INFUSION | MEDICINE | ELEMENTS | NERVOUS SYSTEM DISEASES | FRUCTOSE | THERAPY | AMINO ACIDS | RADIOLOGY AND NUCLEAR MEDICINE | BRAIN | RADIOLOGY | GLIOMAS | SACCHARIDES | NEOPLASMS | ORGANIC COMPOUNDS | INTAKE | ORGANIC ACIDS | CENTRAL NERVOUS SYSTEM | NUCLEAR MEDICINE | HEXOSES | KETONES | ORGANS | MONOSACCHARIDES | DISEASES | ALANINES | NEUTRON THERAPY | CARBOXYLIC ACIDS | BODY | CARBOHYDRATES
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7. Full Text Boron Neutron Capture Therapy in the Treatment of Locally Recurred Head-and-Neck Cancer: Final Analysis of a Phase I/II Trial
by Kankaanranta, Leena, M.D and Seppälä, Tiina, Ph.D and Koivunoro, Hanna, M.Sci and Saarilahti, Kauko, M.D and Atula, Timo, M.D and Collan, Juhani, M.D and Salli, Eero, Ph.D and Kortesniemi, Mika, Ph.D and Uusi-Simola, Jouni, Ph.D and Välimäki, Petteri, M.Sci and Mäkitie, Antti, M.D and Seppänen, Marko, M.D and Minn, Heikki, M.D and Revitzer, Hannu, M.Sci and Kouri, Mauri, M.D and Kotiluoto, Petri, Ph.D and Seren, Tom, Lic. Tech and Auterinen, Iiro, M.Sci and Savolainen, Sauli, Ph.D and Joensuu, Heikki, M.D
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 1, pp. e67 - e75
Purpose To investigate the efficacy and safety of boron neutron capture therapy (BNCT) in the treatment of inoperable head-and-neck cancers that recur locally... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Radiotherapy | Boronophenylalanine | Boron neutron capture therapy | Neoplasm Recurrence, Local - radiotherapy | Confidence Intervals | Prospective Studies | Phenylalanine - analogs & derivatives | Humans | Middle Aged | Fatigue - etiology | Boron Neutron Capture Therapy - adverse effects | Male | Carcinoma, Squamous Cell - radiotherapy | Neoplasm Recurrence, Local - mortality | Osteoradionecrosis - etiology | Carcinoma, Squamous Cell - mortality | Pain - etiology | Adult | Female | Phenylalanine - therapeutic use | Sarcoma - radiotherapy | Radiotherapy Dosage | Boron Neutron Capture Therapy - methods | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Mouth Diseases - etiology | Carcinoma, Adenoid Cystic - mortality | Mucositis - etiology | Aged | Carcinoma, Adenoid Cystic - radiotherapy | Head and Neck Neoplasms - mortality | Xerostomia - etiology | Boron Compounds - therapeutic use | Clinical trials | Care and treatment | Boron-neutron capture therapy | Nuclear radiation | Cancer | Index Medicus | SURGERY | HEAD | PATIENTS | BORON | SAFETY | FATIGUE | OSTEORADIONECROSIS | PHOTONS | NEUTRON CAPTURE THERAPY | EVALUATION | RADIATION DOSES | TOXICITY | CHEMOTHERAPY | IRRADIATION | FRUCTOSE | PAIN | SURVIVAL TIME | SARCOMAS | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | NECK
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8. Full Text Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme—Study design and current status report
by Kawabata, Shinji and Miyatake, Shin-Ichi and Hiramatsu, Ryo and Hirota, Yuki and Miyata, Shiro and Takekita, Yoko and Kuroiwa, Toshihiko and Kirihata, Mitsunori and Sakurai, Yoshinori and Maruhashi, Akira and Ono, Koji
Applied Radiation and Isotopes, ISSN 0969-8043, 2011, Volume 69, Issue 12, pp. 1796 - 1799
Recently, we reported our clinical experiences of boron neutron capture therapy (BNCT) for the newly diagnosed glioblastoma. The major differences of our... 
Temozolomide | Phase II clinical study | Fractionated X-ray irradiation | Boron neutron capture therapy | Glioblastoma | SURVIVAL BENEFIT | BRAIN-TUMORS | CHEMISTRY, INORGANIC & NUCLEAR | BORONOPHENYLALANINE | NUCLEAR SCIENCE & TECHNOLOGY | MALIGNANT GLIOMAS | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Dacarbazine - therapeutic use | Boron Neutron Capture Therapy | Humans | Dacarbazine - analogs & derivatives | Antineoplastic Agents - therapeutic use | Combined Modality Therapy | Brain Neoplasms - drug therapy | Brain Neoplasms - radiotherapy | Glioblastoma - drug therapy | Glioblastoma - radiotherapy | Medical research | Care and treatment | Boron-neutron capture therapy | Medicine, Experimental | Clinical trials | Glioblastoma multiforme
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9. Full Text Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer
by Barth, Rolf F and Vicente, M Graca H and Harling, Otto K and Kiger III, W S and Riley, Kent J and Binns, Peter J and Wagner, Franz M and Suzuki, Minoru and Aihara, Teruhito and Kato, Itsuro and Kawabata, Shinji
Radiation Oncology, ISSN 1748-717X, 08/2012, Volume 7, Issue 1, pp. 146 - 146
Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the nuclear capture and fission reactions that occur when... 
Head and neck cancer | Radiation therapy | Gliomas | Boron neutron capture therapy | EPITHERMAL NEUTRON | DIAGNOSED GLIOBLASTOMA-MULTIFORME | COMPUTATIONAL DOSIMETRY | I CLINICAL-TRIAL | BRAIN-TUMORS | ADJUVANT TEMOZOLOMIDE | MALIGNANT GLIOMA | ONCOLOGY | AMINO-ACIDS | EPIDERMAL-GROWTH-FACTOR | INTERNATIONAL DOSIMETRY EXCHANGE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Neoplasm Recurrence, Local - radiotherapy | Boron Neutron Capture Therapy - instrumentation | Humans | Boron Compounds - administration & dosage | Glioma - radiotherapy | Drug Delivery Systems | Head and Neck Neoplasms - pathology | Boron Neutron Capture Therapy - methods | Head and Neck Neoplasms - radiotherapy | Neoplasm Grading | Models, Biological | Glioma - pathology | Boron Compounds - supply & distribution | Boron Neutron Capture Therapy - trends | Medical research | Relapse | Phenylalanine | Boron-neutron capture therapy | Japan | Melanoma | Radiation | Antineoplastic agents | Natural disasters | Diseases | Antimitotic agents | Medicine, Experimental | Nuclear reactors | Nuclear facilities | Brain | Brain cancer | Colleges & universities | Amino acids | Oncology | Derivatives | Cancer therapies | Manuscripts | Molecular weight | Maxillofacial surgery | Boron | Surgery | Head & neck cancer | Laboratory animals | Tumors | Index Medicus
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