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Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2015, Volume 104, Issue 3, pp. 962 - 970
Carboranyl-containing chlorins have emerged as promising dual sensitizers for use in both photodynamic therapy (PDT) and boron neutron capture therapy (BNCT),... 
PDT | BNCT | blood–brain barrier | CED | absorption | cell culture | boron-containing chlorin | CNS | osmotic pumps | TPFC | boron‐containing chlorin | Cell culture | Absorption | Blood-brain barrier | Osmotic pumps | Boron-containing chlorin | blood-brain barrier | CHEMISTRY, MEDICINAL | BRAIN TUMOR-MODELS | PHOTOSENSITIZING PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | P-BORONOPHENYLALANINE | EPIDERMAL-GROWTH-FACTOR | IN-VIVO | MALIGNANT GLIOMAS | PHARMACOLOGY & PHARMACY | L-ASPARTYL CHLORIN-E6 | CONVECTION-ENHANCED DELIVERY | REAL-TIME | Porphyrins - administration & dosage | Phenylalanine - analogs & derivatives | Phenylalanine - pharmacology | Photochemotherapy - methods | Rats, Inbred F344 | Brain Neoplasms - pathology | Male | Porphyrins - pharmacokinetics | Radiation-Sensitizing Agents - pharmacokinetics | Boron Compounds - administration & dosage | Photosensitizing Agents - administration & dosage | Tissue Distribution | Photosensitizing Agents - pharmacology | Radiation-Sensitizing Agents - administration & dosage | Boron Compounds - chemical synthesis | Glioma - pathology | Glioma - therapy | Radiation-Sensitizing Agents - chemical synthesis | Photosensitizing Agents - chemical synthesis | Boron Compounds - pharmacology | Cell Survival - drug effects | Radiation-Sensitizing Agents - pharmacology | Porphyrins - chemical synthesis | Boron Compounds - pharmacokinetics | Porphyrins - pharmacology | Cell Survival - radiation effects | Boron Neutron Capture Therapy - methods | Animals | Brain Neoplasms - therapy | Cell Line, Tumor | Photosensitizing Agents - pharmacokinetics | Microscopy, Fluorescence
Journal Article
2012, 1. Aufl., ISBN 3642313337, Volume 9783642313349, 544
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and... 
Boron-neutron capture therapy | Clinical & internal medicine | Fast neutrons | Therapeutic use
eBook
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 80, Issue 2, pp. 369 - 376
Purpose To investigate the safety of boronophenylalanine-mediated boron neutron capture therapy (BNCT) in the treatment of malignant gliomas that progress... 
Radiology | Hematology, Oncology and Palliative Medicine | Brain tumor | Boronophenylalanine | Anaplastic astrocytoma | Boron neutron capture therapy | Glioblastoma | CRITERIA | TRIALS | BNCT | GLIOBLASTOMA-MULTIFORME | CANCER | ADJUVANT TEMOZOLOMIDE | BRAIN-TUMORS | BPA | ONCOLOGY | CONCOMITANT | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Astrocytoma - radiotherapy | Boron Neutron Capture Therapy - mortality | Humans | Middle Aged | Brain Neoplasms - pathology | Boron Neutron Capture Therapy - adverse effects | Male | Boron Compounds - administration & dosage | Glioblastoma - radiotherapy | Brain Neoplasms - surgery | Radiation-Sensitizing Agents - therapeutic use | Young Adult | Astrocytoma - pathology | Adult | Female | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Astrocytoma - mortality | Radiotherapy Dosage | Fructose - adverse effects | Radiation-Sensitizing Agents - adverse effects | Disease Progression | Fructose - therapeutic use | Glioblastoma - surgery | Boron Neutron Capture Therapy - methods | Fructose - analogs & derivatives | Maximum Tolerated Dose | Glioblastoma - pathology | Boron Compounds - adverse effects | Aged | Glioblastoma - mortality | Boron Compounds - therapeutic use | Fructose - administration & dosage | Astrocytoma - surgery | Antimitotic agents | Care and treatment | Antineoplastic agents | Gliomas | Boron-neutron capture therapy | Radiation | Boron | Side effects | Glioma | Toxicity | Brain tumors | Surgery | Neutrons | Radiotherapy | Survival | Astrocytoma | Index Medicus | SEMIMETALS | BORON | NERVOUS SYSTEM | NEUTRON CAPTURE THERAPY | INFUSION | MEDICINE | ELEMENTS | NERVOUS SYSTEM DISEASES | FRUCTOSE | THERAPY | AMINO ACIDS | RADIOLOGY AND NUCLEAR MEDICINE | BRAIN | RADIOLOGY | GLIOMAS | SACCHARIDES | NEOPLASMS | ORGANIC COMPOUNDS | INTAKE | ORGANIC ACIDS | CENTRAL NERVOUS SYSTEM | NUCLEAR MEDICINE | HEXOSES | KETONES | ORGANS | MONOSACCHARIDES | DISEASES | ALANINES | NEUTRON THERAPY | CARBOXYLIC ACIDS | BODY | CARBOHYDRATES
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 1, pp. e67 - e75
Purpose To investigate the efficacy and safety of boron neutron capture therapy (BNCT) in the treatment of inoperable head-and-neck cancers that recur locally... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Radiotherapy | Boronophenylalanine | Boron neutron capture therapy | Neoplasm Recurrence, Local - radiotherapy | Confidence Intervals | Prospective Studies | Phenylalanine - analogs & derivatives | Humans | Middle Aged | Fatigue - etiology | Boron Neutron Capture Therapy - adverse effects | Male | Carcinoma, Squamous Cell - radiotherapy | Neoplasm Recurrence, Local - mortality | Osteoradionecrosis - etiology | Carcinoma, Squamous Cell - mortality | Pain - etiology | Adult | Female | Phenylalanine - therapeutic use | Sarcoma - radiotherapy | Radiotherapy Dosage | Boron Neutron Capture Therapy - methods | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Mouth Diseases - etiology | Carcinoma, Adenoid Cystic - mortality | Mucositis - etiology | Aged | Carcinoma, Adenoid Cystic - radiotherapy | Head and Neck Neoplasms - mortality | Xerostomia - etiology | Boron Compounds - therapeutic use | Clinical trials | Care and treatment | Boron-neutron capture therapy | Nuclear radiation | Cancer | Index Medicus | SURGERY | HEAD | PATIENTS | BORON | SAFETY | FATIGUE | OSTEORADIONECROSIS | PHOTONS | NEUTRON CAPTURE THERAPY | EVALUATION | RADIATION DOSES | TOXICITY | CHEMOTHERAPY | IRRADIATION | FRUCTOSE | PAIN | SURVIVAL TIME | SARCOMAS | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | NECK
Journal Article
Journal Article
Radiation Oncology, ISSN 1748-717X, 08/2012, Volume 7, Issue 1, pp. 146 - 146
Journal Article