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PLoS Pathogens, ISSN 1553-7366, 05/2015, Volume 11, Issue 5, pp. e1004929 - e1004929
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 10, pp. 3841 - 3846
The S100A8/S100A9 heterodime/calprotectin (CP) functions in the host response to pathogens through a mechanism termed "nutritional immunity." CP binds Mn²⁺ and... 
Proteins | Pathogens | Antimicrobials | Superoxides | Neutrophils | Bacteria | Infections | Titration | Immunity | Crystal structure | Bacterial pathogenesis | Isothermal titration calorimetry | Protein crystal structure | Staphylococcus aureus | Antibiotic resistance | CALCIUM-BINDING PROTEINS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | protein crystal structure | ESCHERICHIA-COLI | PSORIASIN S100A7 | isothermal titration calorimetry | STRUCTURE VALIDATION | antibiotic resistance | STAPHYLOCOCCUS-AUREUS | METAL | bacterial pathogenesis | SUPEROXIDE-DISMUTASE | ZINC-BINDING | EF-HAND PROTEINS | Zinc - metabolism | Humans | Protein Multimerization | Crystallography, X-Ray | Calgranulin A - genetics | Leukocyte L1 Antigen Complex - immunology | Host-Pathogen Interactions - immunology | Calgranulin A - chemistry | Calgranulin B - immunology | Calgranulin B - genetics | Leukocyte L1 Antigen Complex - pharmacology | Calgranulin A - immunology | Binding Sites | Calgranulin B - chemistry | Mutagenesis, Site-Directed | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Immunity, Innate | Manganese - metabolism | Recombinant Proteins - immunology | Leukocyte L1 Antigen Complex - chemistry | Leukocyte L1 Antigen Complex - genetics | Staphylococcus aureus - immunology | Histidine - chemistry | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Amino Acid Substitution | Molecular dynamics | Host-parasite relationships | Immune response | Research | Health aspects | Manganese compounds | Bacterial infections | Binding sites | Medical immunity | Index Medicus | Biological Sciences
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 03/2012, Volume 11, Issue 3, pp. 227 - 239
Journal Article
PLoS Pathogens, ISSN 1553-7366, 12/2012, Volume 8, Issue 12, pp. e1003068 - e1003068
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 06/2016, Volume 19, Issue 6, pp. 814 - 825
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 04/2003, Volume 111, Issue 7, pp. 1011 - 1020
The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the pulmonary failure that leads to sepsis-related death. In this... 
MEDICINE, RESEARCH & EXPERIMENTAL | BACTERIAL LIPOPOLYSACCHARIDE | CELLS | RECRUITMENT | ENDOTOXIN | P-SELECTIN | MICE | NF-KAPPA-B | EXPRESSION | TLR4 | CUTTING EDGE
Journal Article