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nf-at1 protein (53) 53
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Journal Article
PLoS Biology, ISSN 1544-9173, 01/2018, Volume 16, Issue 1, p. e2004111
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 8/2018, Volume 144, Issue 8, pp. 1445 - 1462
It has been reported that PI3K/AKT pathway is altered in various cancers and AKT isoforms specifically regulate cell growth and metastasis of cancer cells;... 
PHLPP2 | TIS21 /BTG2 | Medicine & Public Health | Hematology | mTORc1, mTORc2 | Oncology | Cancer Research | Internal Medicine | AKT1 | NFAT1 | Triple negative breast cancer | TIS21
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2015, Volume 10, Issue 1, p. e0116575
G-protein-coupled receptor (GPCR) signaling modulates the expression of cytokines that are drug targets for immune disorders. However, although GPCRs are... 
Cell Line | Promoter Regions, Genetic | RNA, Small Interfering - genetics | GTP-Binding Protein gamma Subunits - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Receptors, Antigen, T-Cell - metabolism | Calcium - metabolism | Humans | NFATC Transcription Factors - metabolism | RNA, Messenger - genetics | GTP-Binding Protein beta Subunits - antagonists & inhibitors | Gene Silencing | GTP-Binding Protein gamma Subunits - antagonists & inhibitors | RNA, Messenger - metabolism | Protein Transport | Gene Expression Regulation - drug effects | T-Lymphocytes, Helper-Inducer - drug effects | Interleukin-2 - genetics | Signal Transduction - drug effects | Time Factors | Transcription, Genetic | GTP-Binding Protein beta Subunits - metabolism | Xanthenes - pharmacology | Potentiation | Drugs | Transcription factors | G protein-coupled receptors | Transcription | Laboratories | Leukemia | Interleukin | Helper cells | NF-AT protein | Kinases | Proteins | T-cell receptor | Cell activation | Interleukin 2 | Lymphocytes | Fibroblasts | Inhibition | Localization | Drug dosages | Adenosine | Memory cells | Calcium (intracellular) | Cytokines | RNA-mediated interference | T cell receptors | siRNA | Ribonucleic acid--RNA | CD4 antigen | Signaling | NF-AT1 protein | Plasmids | Rheumatoid arthritis | Autoimmune diseases | Chemokines | Cancer | mRNA stability | RNA | Ribonucleic acid
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 14
Store-operated Ca2+ entry, involving endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels, is a widespread and evolutionary... 
Transcription factors | Calcium channels | Low concentrations | STIM1 protein | Orai1 protein | NF-AT protein | Calcium influx | Recruitment | Signal transduction | NF-AT1 protein | Evolutionary conservation | Clusters | Transduction | Endoplasmic reticulum | c-Fos protein | Calcium ions | Calcium (reticular)
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e30915
Background: Ca2+ handling machinery modulates the activation of cardiac transcription pathways involved in heart failure (HF). The present study investigated... 
MYOCARDIUM | CARDIOMYOCYTE HYPERTROPHY | MYOCYTES | CARDIAC-HYPERTROPHY | IN-VIVO | BIOLOGY | CALCINEURIN | DILATED CARDIOMYOPATHY | CA2+/CALMODULIN-DEPENDENT PROTEIN-KINASE | EXPRESSION | INSIGHTS | Calcium - metabolism | Heart Failure - enzymology | Humans | Middle Aged | Male | Heterochromatin - ultrastructure | Heterochromatin - metabolism | Sodium-Calcium Exchanger - metabolism | Myocardium - metabolism | Ultrasonography | Electrocardiography | Female | Transcription, Genetic | Heart Failure - diagnostic imaging | Heart Failure - etiology | MEF2 Transcription Factors | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Calmodulin - metabolism | GATA4 Transcription Factor - metabolism | Myogenic Regulatory Factors - genetics | MADS Domain Proteins - genetics | NFATC Transcription Factors - metabolism | Myogenic Regulatory Factors - metabolism | Heart Failure - genetics | Myocardium - pathology | Signal Transduction - genetics | Blotting, Western | Protein Transport | MADS Domain Proteins - metabolism | Myocytes, Cardiac - pathology | Myocytes, Cardiac - metabolism | Myocytes, Cardiac - ultrastructure | Subcellular Fractions - enzymology | Calcineurin - metabolism | NFATC Transcription Factors - genetics | Heart failure | Heart | Materials handling | Genetic aspects | Transplantation | Equipment and supplies | Genetic transcription | DNA binding proteins | Health aspects | Fluorescence microscopy | Calmodulin | Cardiac arrhythmia | Transcription factors | Biomedical research | Calcium | Cardiomyopathy | Calcineurin | Genomics | Fluorescence | NF-AT protein | Kinases | Machinery | Western blotting | Proteins | Pathways | Myocyte-specific enhancer-binding factor 2 | Ischemia | Rodents | Calcium-binding protein | Transcription activation | Cardiology | Heart diseases | Translocation | Enzymes | Medical imaging | Heart transplantation | Cardiomyocytes | Electron microscopy | Gene expression | Nuclear transport | Studies | NF-AT1 protein | Handling
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 01/2018, Volume 200, Issue 2, pp. 880 - 880
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e92176
Background: Plasma membrane Ca2+-ATPases (PMCA) extrude Ca2+ ions out of the cell and contribute to generation of calcium oscillations. Calcium signaling is... 
PLASMA-MEMBRANE CA2+-ATPASE | ACTIVATED T-CELLS | MULTIDISCIPLINARY SCIENCES | ADRENAL CHROMAFFIN CELLS | CARDIAC-HYPERTROPHY | NUCLEAR FACTOR | PC12 CELLS | OSTEOCLAST DIFFERENTIATION | TRANSCRIPTIONAL REGULATION | CATECHOLAMINE SECRETION | HIPPOCAMPAL-NEURONS | Luciferases - metabolism | Plasma Membrane Calcium-Transporting ATPases - genetics | Vesicle-Associated Membrane Protein 2 - genetics | PC12 Cells | Plasma Membrane Calcium-Transporting ATPases - metabolism | Calcineurin - genetics | Chromatin Immunoprecipitation | Pheochromocytoma - pathology | Real-Time Polymerase Chain Reaction | Adrenal Gland Neoplasms - pathology | Calcium Signaling | Dopamine - metabolism | Pheochromocytoma - metabolism | Signal Transduction | NFATC Transcription Factors - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Cell Communication | Rats | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Animals | Adrenal Gland Neoplasms - metabolism | Pheochromocytoma - genetics | Vesicle-Associated Membrane Protein 1 - genetics | Vesicle-Associated Membrane Protein 2 - metabolism | Adrenal Gland Neoplasms - genetics | Calcineurin - metabolism | Vesicle-Associated Membrane Protein 1 - metabolism | NFATC Transcription Factors - genetics | Chromatin | Dopamine | Phosphatases | Genes | Phenols | DNA binding proteins | T cells | Adenosine triphosphatase | Membrane proteins | Cell culture | Transcription factors | Complex formation | Immunoprecipitation | Peptides | Calcium | Calcineurin | Gene regulation | Oscillations | SNAP receptors | Intracellular signalling | Activation | Biochemistry | Biology | NF-AT protein | Ca2+-transporting ATPase | Calcium signalling | Proteins | Reduction | Lymphocytes | Cell cycle | Localization | Neurochemistry | Secretion | Gene silencing | NF-AT1 protein | Pheochromocytoma cells | Alzheimers disease | Apoptosis
Journal Article
International Immunopharmacology, ISSN 1567-5769, 03/2018, Volume 56, p. 1
The aim of the work was to investigate the effect and possible mechanism of MENK on the growth of rat C6 glioma in vivo or in vitro. Our findings showed that... 
Bax protein | Bcl-2 protein | Transcription | Brain cancer | Activation | NF-AT protein | Caspase-3 | Receptors | Glioma cells | Translocation | Cell survival | Opioid receptors | Methionine | Rats | Caspase | Caspase-8 | Chemotherapy | NF-AT1 protein | FasL protein | Enkephalins | Caspase-9 | In vivo methods and tests | Nuclei (cytology) | Viability | Cytoplasm | Apoptosis | Tumors
Journal Article
Plos One, ISSN 1932-6203, 2012, Volume 7, Issue 4, pp. e34140 - e34140
Virus host evasion genes are ready-made tools for gene manipulation and therapy. In this work we have assessed the impact in vivo of the evasion gene A238L of... 
CELLS | TARGETED DISRUPTION | CELLULAR PHOSPHATASE CALCINEURIN | TRANSCRIPTIONAL COACTIVATORS | NUCLEAR-FACTOR | IMMUNE-RESPONSES | P300 | BIOLOGY | EVASION | NF-KAPPA-B | MICE LACKING | Blotting, Southern | Thymocytes - metabolism | Molecular Sequence Data | DNA Primers - genetics | Gene Expression Profiling | Neovascularization, Pathologic - virology | Viral Proteins - metabolism | T-Lymphocytes - virology | Flow Cytometry | Histological Techniques | Cell Transformation, Neoplastic - genetics | Base Sequence | Plasmids - genetics | Neovascularization, Pathologic - physiopathology | T-Lymphocytes - pathology | Gene Transfer Techniques | NFATC Transcription Factors - metabolism | Mice, Transgenic | Gene Dosage | Cell Transformation, Neoplastic - metabolism | Sequence Analysis, DNA | CD8 Antigens - metabolism | Animals | Fluorescent Antibody Technique | Mice | CD4 Antigens - metabolism | Lymphoma - virology | Antimitotic agents | Lymphomas | Genetic aspects | Genetic engineering | Genetic transcription | B cells | T cells | Antineoplastic agents | Transformation | Transcription | CD8 antigen | Positive selection | Viruses | Lymphocytes T | Myc protein | NF-AT protein | Kinases | CD69 antigen | Angiogenesis | Interleukin 2 | Swine | Lymphocytes | Rodents | CD25 antigen | Foxp3 protein | Clonal selection | NF-κB protein | African swine fever | Transgenic mice | T cell receptors | Gene expression | Lymphoma | Fever | CD4 antigen | Itk protein | NF-AT1 protein | RAG1 protein | Transformations | Livestock | Gene manipulation | Tumors
Journal Article